DE2966182D1 - A process for preparing cis-2-aryl-3-aminomethyl-bicyclo (2,2,2) octanes and the compounds 2-aryl-3-aminomethylidene-bicyclo (2,2,2) octanes - Google Patents

A process for preparing cis-2-aryl-3-aminomethyl-bicyclo (2,2,2) octanes and the compounds 2-aryl-3-aminomethylidene-bicyclo (2,2,2) octanes

Info

Publication number
DE2966182D1
DE2966182D1 DE7979301355T DE2966182T DE2966182D1 DE 2966182 D1 DE2966182 D1 DE 2966182D1 DE 7979301355 T DE7979301355 T DE 7979301355T DE 2966182 T DE2966182 T DE 2966182T DE 2966182 D1 DE2966182 D1 DE 2966182D1
Authority
DE
Germany
Prior art keywords
octanes
bicyclo
aryl
aminomethylidene
aminomethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE7979301355T
Other languages
English (en)
Inventor
David Christopher Horwell
Graham Henry Timms
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lilly Industries Ltd
Original Assignee
Lilly Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Industries Ltd filed Critical Lilly Industries Ltd
Application granted granted Critical
Publication of DE2966182D1 publication Critical patent/DE2966182D1/de
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/68Preparation of compounds containing amino groups bound to a carbon skeleton from amines, by reactions not involving amino groups, e.g. reduction of unsaturated amines, aromatisation, or substitution of the carbon skeleton
    • C07C209/70Preparation of compounds containing amino groups bound to a carbon skeleton from amines, by reactions not involving amino groups, e.g. reduction of unsaturated amines, aromatisation, or substitution of the carbon skeleton by reduction of unsaturated amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/26Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
    • C07C211/29Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00Systems containing two condensed rings
    • C07C2602/36Systems containing two condensed rings the rings having more than two atoms in common
    • C07C2602/44Systems containing two condensed rings the rings having more than two atoms in common the bicyclo ring system containing eight carbon atoms
DE7979301355T 1978-07-15 1979-07-11 A process for preparing cis-2-aryl-3-aminomethyl-bicyclo (2,2,2) octanes and the compounds 2-aryl-3-aminomethylidene-bicyclo (2,2,2) octanes Expired DE2966182D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7829988 1978-07-15

Publications (1)

Publication Number Publication Date
DE2966182D1 true DE2966182D1 (en) 1983-10-27

Family

ID=10498451

Family Applications (1)

Application Number Title Priority Date Filing Date
DE7979301355T Expired DE2966182D1 (en) 1978-07-15 1979-07-11 A process for preparing cis-2-aryl-3-aminomethyl-bicyclo (2,2,2) octanes and the compounds 2-aryl-3-aminomethylidene-bicyclo (2,2,2) octanes

Country Status (31)

Country Link
US (1) US4215074A (de)
EP (1) EP0008163B1 (de)
JP (1) JPS5515476A (de)
KR (1) KR820000628B1 (de)
AR (1) AR221885A1 (de)
AT (1) AT366661B (de)
AU (1) AU530973B2 (de)
BE (1) BE877674A (de)
CA (1) CA1131253A (de)
CH (1) CH640821A5 (de)
CS (1) CS215118B2 (de)
DD (1) DD144913A5 (de)
DE (1) DE2966182D1 (de)
DK (1) DK150822C (de)
EG (1) EG14307A (de)
ES (1) ES482462A1 (de)
FI (1) FI65230C (de)
FR (1) FR2430931A1 (de)
GR (1) GR69639B (de)
HU (1) HU181902B (de)
IE (1) IE48773B1 (de)
IL (1) IL57779A (de)
LU (1) LU81498A1 (de)
MX (1) MX5510E (de)
NZ (1) NZ190991A (de)
PH (1) PH15975A (de)
PL (1) PL119592B1 (de)
PT (1) PT69908A (de)
RO (1) RO78312A (de)
YU (1) YU169879A (de)
ZA (1) ZA793518B (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4019782A1 (de) * 1990-06-21 1992-01-02 Basf Ag 9-amino-2-phenylbicyclo (3.3.1.) und 9-amino-2-phenylbicyclo (3.3.1.) non-2-ene und diese enthaltende therapeutische mittel

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT219020B (de) * 1959-08-01 1962-01-10 Merck Ag E Verfahren zur Herstellung von neuen N-substituierten Amino-norcamphanderivaten sowie deren Säureadditionssalzen und quaternären Ammoniumverbindungen
US3148118A (en) * 1962-06-05 1964-09-08 Thesing Jan Analeptically active agents
US3228984A (en) * 1963-11-04 1966-01-11 American Home Prod 1, 4-bis-cyclic and aryl-amino-[2.2.2] bicyclooctane derivatives
US3264351A (en) * 1964-07-08 1966-08-02 American Home Prod 1, 4-diaminobicyclo [2.2.2] octanes
US3515740A (en) * 1967-02-20 1970-06-02 Orville D Frampton Cyano cyclohexenyl compounds
GB1444717A (en) * 1972-11-04 1976-08-04 Lilly Industries Ltd Bicycloalkyl derivatives
GB1549174A (en) * 1975-05-08 1979-08-01 Lilly Industries Ltd Amine derivatives
AT345781B (de) * 1975-05-08 1978-10-10 Lilly Industries Ltd Verfahren zur herstellung von neuen 3- aminomethyl-2-phenylbicyclo (2,2,2) octanen und -octenen sowie deren saeureadditionssalzen

Also Published As

Publication number Publication date
FR2430931A1 (fr) 1980-02-08
FI65230B (fi) 1983-12-30
FI792192A (fi) 1980-01-16
CS215118B2 (en) 1982-07-30
FI65230C (fi) 1984-04-10
US4215074A (en) 1980-07-29
PH15975A (en) 1983-05-11
AU530973B2 (en) 1983-08-04
PL217118A1 (de) 1980-07-01
GR69639B (de) 1982-07-06
CA1131253A (en) 1982-09-07
DK150822C (da) 1988-01-25
HU181902B (en) 1983-11-28
JPS5515476A (en) 1980-02-02
FR2430931B1 (de) 1984-01-20
BE877674A (fr) 1980-01-14
KR820000628B1 (ko) 1982-04-19
EP0008163B1 (de) 1983-09-21
CH640821A5 (fr) 1984-01-31
IE791324L (en) 1980-01-15
IE48773B1 (en) 1985-05-15
PL119592B1 (en) 1982-01-30
EG14307A (en) 1983-09-30
EP0008163A1 (de) 1980-02-20
PT69908A (en) 1979-08-01
DD144913A5 (de) 1980-11-12
DK294079A (da) 1980-01-16
AU4888779A (en) 1980-01-24
MX5510E (es) 1983-09-06
IL57779A0 (en) 1979-11-30
IL57779A (en) 1983-02-23
RO78312A (ro) 1982-04-12
AT366661B (de) 1982-04-26
AR221885A1 (es) 1981-03-31
NZ190991A (en) 1981-04-24
YU169879A (en) 1983-04-30
ES482462A1 (es) 1980-04-01
ZA793518B (en) 1981-02-25
DK150822B (da) 1987-06-29
LU81498A1 (fr) 1981-02-03
ATA484179A (de) 1981-09-15

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Legal Events

Date Code Title Description
8328 Change in the person/name/address of the agent

Free format text: TUERK, D., DIPL.-CHEM. DR.RER.NAT. GILLE, C., DIPL.-ING., PAT.-ANW., 4000 DUESSELDORF

8339 Ceased/non-payment of the annual fee