DE2954176C2 - Kontaktlinse - Google Patents
KontaktlinseInfo
- Publication number
- DE2954176C2 DE2954176C2 DE2954176A DE2954176A DE2954176C2 DE 2954176 C2 DE2954176 C2 DE 2954176C2 DE 2954176 A DE2954176 A DE 2954176A DE 2954176 A DE2954176 A DE 2954176A DE 2954176 C2 DE2954176 C2 DE 2954176C2
- Authority
- DE
- Germany
- Prior art keywords
- lens
- contact lens
- well
- ester
- eye
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000002148 esters Chemical class 0.000 claims description 55
- VHSHLMUCYSAUQU-UHFFFAOYSA-N 2-hydroxypropyl methacrylate Chemical compound CC(O)COC(=O)C(C)=C VHSHLMUCYSAUQU-UHFFFAOYSA-N 0.000 claims description 17
- 239000003054 catalyst Substances 0.000 claims description 9
- 239000002253 acid Substances 0.000 claims description 6
- 150000002978 peroxides Chemical class 0.000 claims description 6
- 229920003023 plastic Polymers 0.000 claims description 6
- 239000004033 plastic Substances 0.000 claims description 6
- HFCUBKYHMMPGBY-UHFFFAOYSA-N 2-methoxyethyl prop-2-enoate Chemical compound COCCOC(=O)C=C HFCUBKYHMMPGBY-UHFFFAOYSA-N 0.000 claims description 5
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 claims description 5
- YXYJVFYWCLAXHO-UHFFFAOYSA-N 2-methoxyethyl 2-methylprop-2-enoate Chemical compound COCCOC(=O)C(C)=C YXYJVFYWCLAXHO-UHFFFAOYSA-N 0.000 claims description 4
- JHWGFJBTMHEZME-UHFFFAOYSA-N 4-prop-2-enoyloxybutyl prop-2-enoate Chemical compound C=CC(=O)OCCCCOC(=O)C=C JHWGFJBTMHEZME-UHFFFAOYSA-N 0.000 claims description 4
- ULQMPOIOSDXIGC-UHFFFAOYSA-N [2,2-dimethyl-3-(2-methylprop-2-enoyloxy)propyl] 2-methylprop-2-enoate Chemical compound CC(=C)C(=O)OCC(C)(C)COC(=O)C(C)=C ULQMPOIOSDXIGC-UHFFFAOYSA-N 0.000 claims description 4
- 229920001843 polymethylhydrosiloxane Polymers 0.000 claims description 4
- YKXAYLPDMSGWEV-UHFFFAOYSA-N 4-hydroxybutyl 2-methylprop-2-enoate Chemical compound CC(=C)C(=O)OCCCCO YKXAYLPDMSGWEV-UHFFFAOYSA-N 0.000 claims description 3
- FIHBHSQYSYVZQE-UHFFFAOYSA-N 6-prop-2-enoyloxyhexyl prop-2-enoate Chemical compound C=CC(=O)OCCCCCCOC(=O)C=C FIHBHSQYSYVZQE-UHFFFAOYSA-N 0.000 claims description 3
- XXMIOPMDWAUFGU-UHFFFAOYSA-N hexane-1,6-diol Chemical compound OCCCCCCO XXMIOPMDWAUFGU-UHFFFAOYSA-N 0.000 claims description 3
- 238000007334 copolymerization reaction Methods 0.000 claims description 2
- XOJWAAUYNWGQAU-UHFFFAOYSA-N 4-(2-methylprop-2-enoyloxy)butyl 2-methylprop-2-enoate Chemical compound CC(=C)C(=O)OCCCCOC(=O)C(C)=C XOJWAAUYNWGQAU-UHFFFAOYSA-N 0.000 claims 1
- LYCAIKOWRPUZTN-UHFFFAOYSA-N ethylene glycol Natural products OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 claims 1
- -1 polysiloxane Polymers 0.000 description 45
- 239000000463 material Substances 0.000 description 32
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 31
- 238000005266 casting Methods 0.000 description 28
- 229920000642 polymer Polymers 0.000 description 28
- 235000013870 dimethyl polysiloxane Nutrition 0.000 description 25
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 description 25
- 229920001296 polysiloxane Polymers 0.000 description 25
- 150000001875 compounds Chemical class 0.000 description 24
- 239000000203 mixture Substances 0.000 description 24
- 239000004205 dimethyl polysiloxane Substances 0.000 description 23
- 238000000034 method Methods 0.000 description 19
- 229920001577 copolymer Polymers 0.000 description 18
- 230000035699 permeability Effects 0.000 description 17
- 229920001897 terpolymer Polymers 0.000 description 17
- 230000001179 pupillary effect Effects 0.000 description 16
- 238000009736 wetting Methods 0.000 description 16
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 15
- 238000010521 absorption reaction Methods 0.000 description 15
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 14
- 210000004087 cornea Anatomy 0.000 description 14
- 239000012530 fluid Substances 0.000 description 14
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 13
- 239000001301 oxygen Substances 0.000 description 13
- 229910052760 oxygen Inorganic materials 0.000 description 13
- 239000000523 sample Substances 0.000 description 13
- 230000005540 biological transmission Effects 0.000 description 11
- 210000000744 eyelid Anatomy 0.000 description 10
- 238000004519 manufacturing process Methods 0.000 description 10
- 239000002904 solvent Substances 0.000 description 10
- 239000007788 liquid Substances 0.000 description 9
- 230000003287 optical effect Effects 0.000 description 9
- WERYXYBDKMZEQL-UHFFFAOYSA-N butane-1,4-diol Chemical compound OCCCCO WERYXYBDKMZEQL-UHFFFAOYSA-N 0.000 description 8
- 239000012528 membrane Substances 0.000 description 8
- 239000000243 solution Substances 0.000 description 8
- 229910002092 carbon dioxide Inorganic materials 0.000 description 7
- 239000001569 carbon dioxide Substances 0.000 description 7
- ZWEHNKRNPOVVGH-UHFFFAOYSA-N 2-Butanone Chemical compound CCC(C)=O ZWEHNKRNPOVVGH-UHFFFAOYSA-N 0.000 description 6
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 6
- 238000004132 cross linking Methods 0.000 description 6
- 230000036571 hydration Effects 0.000 description 6
- 238000006703 hydration reaction Methods 0.000 description 6
- 238000002156 mixing Methods 0.000 description 6
- 230000008569 process Effects 0.000 description 6
- 230000015572 biosynthetic process Effects 0.000 description 5
- 230000029142 excretion Effects 0.000 description 5
- 230000002209 hydrophobic effect Effects 0.000 description 5
- 238000001727 in vivo Methods 0.000 description 5
- 150000002632 lipids Chemical class 0.000 description 5
- 238000006116 polymerization reaction Methods 0.000 description 5
- 150000003254 radicals Chemical class 0.000 description 5
- 239000011347 resin Substances 0.000 description 5
- 229920005989 resin Polymers 0.000 description 5
- 210000003786 sclera Anatomy 0.000 description 5
- 239000004925 Acrylic resin Substances 0.000 description 4
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 4
- OSGAYBCDTDRGGQ-UHFFFAOYSA-L calcium sulfate Chemical compound [Ca+2].[O-]S([O-])(=O)=O OSGAYBCDTDRGGQ-UHFFFAOYSA-L 0.000 description 4
- 230000008859 change Effects 0.000 description 4
- KPUWHANPEXNPJT-UHFFFAOYSA-N disiloxane Chemical class [SiH3]O[SiH3] KPUWHANPEXNPJT-UHFFFAOYSA-N 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 239000000945 filler Substances 0.000 description 4
- 239000000049 pigment Substances 0.000 description 4
- 229920003229 poly(methyl methacrylate) Polymers 0.000 description 4
- 239000004926 polymethyl methacrylate Substances 0.000 description 4
- 238000011417 postcuring Methods 0.000 description 4
- 238000012876 topography Methods 0.000 description 4
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 description 3
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 3
- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 description 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
- 239000004793 Polystyrene Substances 0.000 description 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 description 3
- 238000007792 addition Methods 0.000 description 3
- 238000012644 addition polymerization Methods 0.000 description 3
- 239000002956 ash Substances 0.000 description 3
- 150000005690 diesters Chemical class 0.000 description 3
- 229920001971 elastomer Polymers 0.000 description 3
- 239000000806 elastomer Substances 0.000 description 3
- 239000000839 emulsion Substances 0.000 description 3
- 239000001257 hydrogen Substances 0.000 description 3
- 229910052739 hydrogen Inorganic materials 0.000 description 3
- 238000007654 immersion Methods 0.000 description 3
- 230000004060 metabolic process Effects 0.000 description 3
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 3
- 231100000252 nontoxic Toxicity 0.000 description 3
- 230000003000 nontoxic effect Effects 0.000 description 3
- 239000000377 silicon dioxide Substances 0.000 description 3
- 230000004304 visual acuity Effects 0.000 description 3
- 230000004584 weight gain Effects 0.000 description 3
- 235000019786 weight gain Nutrition 0.000 description 3
- OZAIFHULBGXAKX-UHFFFAOYSA-N 2-(2-cyanopropan-2-yldiazenyl)-2-methylpropanenitrile Chemical compound N#CC(C)(C)N=NC(C)(C)C#N OZAIFHULBGXAKX-UHFFFAOYSA-N 0.000 description 2
- XNWFRZJHXBZDAG-UHFFFAOYSA-N 2-METHOXYETHANOL Chemical compound COCCO XNWFRZJHXBZDAG-UHFFFAOYSA-N 0.000 description 2
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 description 2
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 2
- 229920000178 Acrylic resin Polymers 0.000 description 2
- VYZAMTAEIAYCRO-UHFFFAOYSA-N Chromium Chemical compound [Cr] VYZAMTAEIAYCRO-UHFFFAOYSA-N 0.000 description 2
- 239000004593 Epoxy Substances 0.000 description 2
- ZZSNKZQZMQGXPY-UHFFFAOYSA-N Ethyl cellulose Chemical compound CCOCC1OC(OC)C(OCC)C(OCC)C1OC1C(O)C(O)C(OC)C(CO)O1 ZZSNKZQZMQGXPY-UHFFFAOYSA-N 0.000 description 2
- 239000001856 Ethyl cellulose Substances 0.000 description 2
- PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 description 2
- 241000283973 Oryctolagus cuniculus Species 0.000 description 2
- 229910000831 Steel Inorganic materials 0.000 description 2
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 description 2
- XTXRWKRVRITETP-UHFFFAOYSA-N Vinyl acetate Chemical compound CC(=O)OC=C XTXRWKRVRITETP-UHFFFAOYSA-N 0.000 description 2
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 2
- 238000013019 agitation Methods 0.000 description 2
- 150000001298 alcohols Chemical class 0.000 description 2
- XXROGKLTLUQVRX-UHFFFAOYSA-N allyl alcohol Chemical compound OCC=C XXROGKLTLUQVRX-UHFFFAOYSA-N 0.000 description 2
- INDXRDWMTVLQID-UHFFFAOYSA-N butane-1,4-diol Chemical compound OCCCCO.OCCCCO INDXRDWMTVLQID-UHFFFAOYSA-N 0.000 description 2
- 229920002301 cellulose acetate Polymers 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 229910052804 chromium Inorganic materials 0.000 description 2
- 239000011651 chromium Substances 0.000 description 2
- ZQMIGQNCOMNODD-UHFFFAOYSA-N diacetyl peroxide Chemical compound CC(=O)OOC(C)=O ZQMIGQNCOMNODD-UHFFFAOYSA-N 0.000 description 2
- 239000000428 dust Substances 0.000 description 2
- 229920001249 ethyl cellulose Polymers 0.000 description 2
- 235000019325 ethyl cellulose Nutrition 0.000 description 2
- HJJLDNAELNDBBL-UHFFFAOYSA-N hexane-1,6-diol Chemical compound OCCCCCCO.OCCCCCCO HJJLDNAELNDBBL-UHFFFAOYSA-N 0.000 description 2
- 230000001771 impaired effect Effects 0.000 description 2
- 239000003999 initiator Substances 0.000 description 2
- 238000003780 insertion Methods 0.000 description 2
- 230000037431 insertion Effects 0.000 description 2
- HJOVHMDZYOCNQW-UHFFFAOYSA-N isophorone Chemical compound CC1=CC(=O)CC(C)(C)C1 HJOVHMDZYOCNQW-UHFFFAOYSA-N 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 230000005499 meniscus Effects 0.000 description 2
- 230000002503 metabolic effect Effects 0.000 description 2
- YDKNBNOOCSNPNS-UHFFFAOYSA-N methyl 1,3-benzoxazole-2-carboxylate Chemical compound C1=CC=C2OC(C(=O)OC)=NC2=C1 YDKNBNOOCSNPNS-UHFFFAOYSA-N 0.000 description 2
- 229920000609 methyl cellulose Polymers 0.000 description 2
- 239000001923 methylcellulose Substances 0.000 description 2
- 235000010981 methylcellulose Nutrition 0.000 description 2
- SLCVBVWXLSEKPL-UHFFFAOYSA-N neopentyl glycol Chemical compound OCC(C)(C)CO SLCVBVWXLSEKPL-UHFFFAOYSA-N 0.000 description 2
- 239000012860 organic pigment Substances 0.000 description 2
- 238000012643 polycondensation polymerization Methods 0.000 description 2
- 229920002223 polystyrene Polymers 0.000 description 2
- 238000012805 post-processing Methods 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- YPFDHNVEDLHUCE-UHFFFAOYSA-N propane-1,3-diol Chemical compound OCCCO YPFDHNVEDLHUCE-UHFFFAOYSA-N 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 229920002050 silicone resin Polymers 0.000 description 2
- 239000011780 sodium chloride Substances 0.000 description 2
- 239000010959 steel Substances 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 238000010998 test method Methods 0.000 description 2
- 238000002834 transmittance Methods 0.000 description 2
- 235000015112 vegetable and seed oil Nutrition 0.000 description 2
- 239000008158 vegetable oil Substances 0.000 description 2
- 239000002699 waste material Substances 0.000 description 2
- 230000037303 wrinkles Effects 0.000 description 2
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 description 1
- 229920002818 (Hydroxyethyl)methacrylate Polymers 0.000 description 1
- KJCVRFUGPWSIIH-UHFFFAOYSA-N 1-naphthol Chemical compound C1=CC=C2C(O)=CC=CC2=C1 KJCVRFUGPWSIIH-UHFFFAOYSA-N 0.000 description 1
- JQRBBVRBGGXTLZ-UHFFFAOYSA-N 2-methoxyethanol Chemical compound COCCO.COCCO JQRBBVRBGGXTLZ-UHFFFAOYSA-N 0.000 description 1
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 description 1
- 229910000851 Alloy steel Inorganic materials 0.000 description 1
- 239000004342 Benzoyl peroxide Substances 0.000 description 1
- OMPJBNCRMGITSC-UHFFFAOYSA-N Benzoylperoxide Chemical compound C=1C=CC=CC=1C(=O)OOC(=O)C1=CC=CC=C1 OMPJBNCRMGITSC-UHFFFAOYSA-N 0.000 description 1
- 206010056476 Corneal irritation Diseases 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 235000002918 Fraxinus excelsior Nutrition 0.000 description 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 1
- WOBHKFSMXKNTIM-UHFFFAOYSA-N Hydroxyethyl methacrylate Chemical compound CC(=C)C(=O)OCCO WOBHKFSMXKNTIM-UHFFFAOYSA-N 0.000 description 1
- YIVJZNGAASQVEM-UHFFFAOYSA-N Lauroyl peroxide Chemical compound CCCCCCCCCCCC(=O)OOC(=O)CCCCCCCCCCC YIVJZNGAASQVEM-UHFFFAOYSA-N 0.000 description 1
- 206010027646 Miosis Diseases 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- 206010047571 Visual impairment Diseases 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 150000001253 acrylic acids Chemical class 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 239000012736 aqueous medium Substances 0.000 description 1
- IRERQBUNZFJFGC-UHFFFAOYSA-L azure blue Chemical compound [Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Al+3].[Al+3].[Al+3].[Al+3].[Al+3].[Al+3].[S-]S[S-].[O-][Si]([O-])([O-])[O-].[O-][Si]([O-])([O-])[O-].[O-][Si]([O-])([O-])[O-].[O-][Si]([O-])([O-])[O-].[O-][Si]([O-])([O-])[O-].[O-][Si]([O-])([O-])[O-] IRERQBUNZFJFGC-UHFFFAOYSA-L 0.000 description 1
- 235000015241 bacon Nutrition 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 235000019400 benzoyl peroxide Nutrition 0.000 description 1
- 230000004397 blinking Effects 0.000 description 1
- MTAZNLWOLGHBHU-UHFFFAOYSA-N butadiene-styrene rubber Chemical compound C=CC=C.C=CC1=CC=CC=C1 MTAZNLWOLGHBHU-UHFFFAOYSA-N 0.000 description 1
- 239000001273 butane Substances 0.000 description 1
- 125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 230000003197 catalytic effect Effects 0.000 description 1
- 239000007795 chemical reaction product Substances 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 235000019506 cigar Nutrition 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 230000005494 condensation Effects 0.000 description 1
- 230000002354 daily effect Effects 0.000 description 1
- XJOBOFWTZOKMOH-UHFFFAOYSA-N decanoyl decaneperoxoate Chemical compound CCCCCCCCCC(=O)OOC(=O)CCCCCCCCC XJOBOFWTZOKMOH-UHFFFAOYSA-N 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000006735 deficit Effects 0.000 description 1
- 238000004512 die casting Methods 0.000 description 1
- 125000000118 dimethyl group Chemical group [H]C([H])([H])* 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 238000005886 esterification reaction Methods 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000011888 foil Substances 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 150000004678 hydrides Chemical class 0.000 description 1
- 229920001477 hydrophilic polymer Polymers 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000001746 injection moulding Methods 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- 238000011545 laboratory measurement Methods 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 230000001404 mediated effect Effects 0.000 description 1
- 239000000155 melt Substances 0.000 description 1
- 230000007102 metabolic function Effects 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 239000012778 molding material Substances 0.000 description 1
- 230000006855 networking Effects 0.000 description 1
- 229910052759 nickel Inorganic materials 0.000 description 1
- VIKNJXKGJWUCNN-XGXHKTLJSA-N norethisterone Chemical compound O=C1CC[C@@H]2[C@H]3CC[C@](C)([C@](CC4)(O)C#C)[C@@H]4[C@@H]3CCC2=C1 VIKNJXKGJWUCNN-XGXHKTLJSA-N 0.000 description 1
- 150000001451 organic peroxides Chemical class 0.000 description 1
- 239000007800 oxidant agent Substances 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 229920001084 poly(chloroprene) Polymers 0.000 description 1
- 229920000306 polymethylpentene Polymers 0.000 description 1
- 239000011116 polymethylpentene Substances 0.000 description 1
- 235000020004 porter Nutrition 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 238000005086 pumping Methods 0.000 description 1
- 210000001747 pupil Anatomy 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 239000012763 reinforcing filler Substances 0.000 description 1
- 102000012498 secondary active transmembrane transporter activity proteins Human genes 0.000 description 1
- 108040003878 secondary active transmembrane transporter activity proteins Proteins 0.000 description 1
- 235000012239 silicon dioxide Nutrition 0.000 description 1
- 229920002379 silicone rubber Polymers 0.000 description 1
- 238000002791 soaking Methods 0.000 description 1
- 238000002798 spectrophotometry method Methods 0.000 description 1
- 230000005477 standard model Effects 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 229920003002 synthetic resin Polymers 0.000 description 1
- 239000000057 synthetic resin Substances 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 229920001169 thermoplastic Polymers 0.000 description 1
- 239000004416 thermosoftening plastic Substances 0.000 description 1
- 239000004408 titanium dioxide Substances 0.000 description 1
- 235000013799 ultramarine blue Nutrition 0.000 description 1
- 229920002554 vinyl polymer Polymers 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K5/00—Use of organic ingredients
- C08K5/04—Oxygen-containing compounds
- C08K5/10—Esters; Ether-esters
- C08K5/101—Esters; Ether-esters of monocarboxylic acids
- C08K5/103—Esters; Ether-esters of monocarboxylic acids with polyalcohols
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29D—PRODUCING PARTICULAR ARTICLES FROM PLASTICS OR FROM SUBSTANCES IN A PLASTIC STATE
- B29D11/00—Producing optical elements, e.g. lenses or prisms
- B29D11/00009—Production of simple or compound lenses
- B29D11/00038—Production of contact lenses
- B29D11/00125—Auxiliary operations, e.g. removing oxygen from the mould, conveying moulds from a storage to the production line in an inert atmosphere
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F283/00—Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G
- C08F283/12—Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G on to polysiloxanes
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F283/00—Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G
- C08F283/12—Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G on to polysiloxanes
- C08F283/124—Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G on to polysiloxanes on to polysiloxanes having carbon-to-carbon double bonds
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G77/00—Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
- C08G77/42—Block-or graft-polymers containing polysiloxane sequences
- C08G77/442—Block-or graft-polymers containing polysiloxane sequences containing vinyl polymer sequences
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K5/00—Use of organic ingredients
- C08K5/04—Oxygen-containing compounds
- C08K5/10—Esters; Ether-esters
- C08K5/11—Esters; Ether-esters of acyclic polycarboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L83/00—Compositions of macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon only; Compositions of derivatives of such polymers
- C08L83/04—Polysiloxanes
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B1/00—Optical elements characterised by the material of which they are made; Optical coatings for optical elements
- G02B1/04—Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
- G02B1/041—Lenses
- G02B1/043—Contact lenses
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G77/00—Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
- C08G77/04—Polysiloxanes
- C08G77/12—Polysiloxanes containing silicon bound to hydrogen
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G77/00—Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
- C08G77/04—Polysiloxanes
- C08G77/20—Polysiloxanes containing silicon bound to unsaturated aliphatic groups
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G77/00—Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
- C08G77/42—Block-or graft-polymers containing polysiloxane sequences
- C08G77/445—Block-or graft-polymers containing polysiloxane sequences containing polyester sequences
Description
9. Kontaktlinse nach Anspruch 1, dadurch gekennzeichnet, daß sie aus einem Copolymeren hergestellt ist,
10. Kontaktlinse nach Anspruch 1, dadurch gekennzeichnet, daß sie aus einem Copolymeren hergestellt ist, in welchem der Ester aus Neopentylglykoldimethacrylat in einer Menge von etwa 3 Gew.-% besteht.
Fig. 2-4 sind Querschnitte durch erfindungsgemäß ausgebildete Kontaktlinsen.
HOCH2Ch2CH2CH2OH
(Propylenglykolmonomethacrylat)
O
O
O
CH3
Nr.
O
Besonders bevorzugte Ester für die Copolymer- und Terpolymerkombinationen sind:
ASTM- | Bereich | Mittelwert |
Prüfverfahren | ||
D7.85 | etwa 15-95 | 32 |
D1505 | etwa 0,95-1,04 | 1,02 |
D882 | etwa 0,7-7 | 5,6-6,5 |
D882 | etwa 120-250 | 150 |
D1004 | etwa 4,5-13,6 | 11,3 |
D57O | etwa 0-3 | 0,5 |
Gasdurchlässigkeit | etwa 29-62 x 10"9 | 50 x 10"9 |
(h cm3) (cm Wandstärke) | etwa 180-315 x 10"' | 30OX 10"9 |
(see) (s cm Fläche) (cm Hg Druckabfall) | etwa 1,390-1,50 | 1,409 ±0,01 |
O-rDurchlässigkeit D1434 | ||
CO2-Durchlässigkeit D1434 | ||
Brechzahl D542 | ||
nach der
Erfindung
Zur Erzielung voller Hydratisierung benötigte Immersionszeit |
Abweisung von Mukoiden, Lipiden und teilchenfbrm. Schmutz |
14 Tage | schlecht |
7 Tage | annehmbar |
48 Stunden | gut |
29 Stunden | gut |
12-18 Stunden | gut |
12-18 Stunden | gut |
12-18 Stunden | gut |
12-18 Stunden | aii9PP7pir-hnpt |
99,9 99,8 99,5 99,0 98,0 97,0 95,0
Zusammensetzung | (Gew.-0/,) | 2-ΪΪΡΜΑ | Haltbarkeitsdauer |
Föiysiioxan | 0 | des Films | |
a | 100 | 0,1 | 20- 50 Minuten |
b | 99,0 | 0,2 | 35- 65 Minuten |
C | 99,2 | 0,5 | 120-150 Minuten |
d | 99,5 | 1,0 | 140-180 Minuten |
e | 99,0 | 2,0 | 160-180 Sekunden |
f | 98,0 | 3,0 | 160-180 Sekunden |
g | 97,0 | 5,0 | 160-180 Sekunden |
h | 95,0 | 150-180 Sekunden | |
Zusammensetzung | des | Oberfläche | Oberfläche | Oberfläche | |
Copolymeren | hydrophil | lipophil | mueophob | ||
2-HMPA | DMPSrtv | ||||
a | 0,0 | 100,0 | schlecht | ausgez. | ausgez. |
b | 0,1 | 99,9 | annehmb. | sehr gut | sehr gut |
0,2 | 99,8 | gut | gut | gut | |
d | 0,3 | 99,7 | gut | annehmb. | annehmb. |
e | 0,5 | 99,5 | ausgez. | schlecht | schlecht |
f | 1,0 | 99,0 | ausgez. | schlecht | schlecht |
g | 2,0 | 98,0 | ausgez. | schlecht | schlecht |
h | 3,0 | 97,0 | ausgez. | schlecht | schlecht |
i | 5,0 | 95,0 | ausgez. | schlecht | schlecht |
Prozentsatz der bedeckt | Bewertung |
gebliebenen Rasterquadrate | |
2% oder weniger | ausgezeichnet |
2 bis 5% | sehr gut |
5 bis 7% | gut |
7 bis 10% | annehmbar |
mehr als 10% | schlecht |
Estermenge | 15 | 0,2 | Lichtdurch |
0,5 | lässigkeit | ||
(Gew.-%) | 1,0 | % | |
20 2,0 | |||
3,0 | 90 | ||
90 | |||
88 | |||
leichter Schleier | |||
Schleier, opak |
Eigensch.
30 | Estermenge | Lichtdurch | Dehnung | Benetzung | Antistat. | H2O |
lässigkeit | Eigensch. | Absorption | ||||
(Gew.-%) | % | % | % | |||
35 | 0,2 | über 90 | schlecht | |||
0,5 | über 90 | annehmbar | ||||
1,0 | über 90 | gut | ||||
2,0 | 60 | ausgezeichnet | gut | |||
40 | 3,0 | ausgezeichnet | ||||
4,0 | ausgezeichnet | |||||
5,0 | ausgezeichnet | |||||
7,5 | So | ausgezeichnet | ||||
45 |
Estermenge | 55 | 0,2 | Lichtdurch |
0,5 | lässigkeit | ||
(Gew.-%) | 1,0 | % | |
60 2,0 | |||
3,0 | |||
4,0 | |||
5,0 | 89 | ||
65 7,5 | 89 | ||
89 | |||
85 | |||
70 | |||
opak |
Eigensch.
Eigensch.
Absorption
0,2 | 88 |
0,5 | klar |
1,0 | klar |
2,0 | klar |
3,0 | klar |
4,0 | klar |
5,0 | klar |
6,0 | klar |
7,5 | |
10,0 | |
schlecht | gut |
schlecht | |
ausgezeichnet | gut |
ausgezeichnet | |
ausgezeichnet | schlecht |
gut | |
gut | |
gut | |
ausgezeichnet | |
Eigensch.
schlecht | schlecht |
schlecht | schlecht |
gut |
Eigensch.
Absorption
0,2 | 91 |
0,5 | 91 |
1,0 | 91 |
2,0 | 91 |
3,0 | 91 |
4,0 | 91 |
5,0 | 91 |
7,5 | 91 |
12,5 | 91 |
annehmbar | annehmbar |
annehmbar | annehmbar |
gut | |
annehmbar | |
annehmbar | |
annehmbar | |
schlecht | |
gut | |
gut |
5 | I | 30 | I | 55 | Estermenge | 29 54 176 | Dehnung Benetzung | annehmbar | Antistat. H2O | Polydimethylsiloxancopolymer mit 1.4-Butandioldimeihacrylat | Dehnung Benetzung | schlecht | Antistat. H2O | schlecht | Dehnung Benetzung | schlecht | Antistat. H2O | schlecht | |
I | Beispiel 7 | annehmbar | Eigensch. Absorption | Lichtdurch | annehmbar | Eigensch. Absorption | schlecht | Eigensch. Absorptioi | schlecht | ||||||||||
(Gew.-%) | % | gut | % | lässigkeit | % | gut | % | gut | % | annehmbar | II/ /<> |
annehmbar | |||||||
10 | IC | 60 | 0,2 | gut | % | gut | ausgezeichnet | schlecht | |||||||||||
Jj | 65 | 0,5 | Polydimethylsiloxancopolymer mit 1.4-Butandioldiacrylat | ausgezeichnet | gut | ausgezeichnet | gut | ||||||||||||
1,0 | Lichtdurch | ausgezeichnet | ausgezeichnet | gut | |||||||||||||||
40 | 2,0 | lässigkeit | Beispiel 8 | 90 | ausgezeichnet | ausgezeichnet | gut | ||||||||||||
15 | 3,0 | % | Beispiel 9 | ausgezeichnet | gut | ||||||||||||||
4,0 | 90 | 90 | leichter Schleier ausgezeichnet | gut | |||||||||||||||
90 | Polydimethylsiloxancopolymer mit Neopentylglykoldiacrylat | ||||||||||||||||||
20 | 45 | 90 | Lichtdurch | ||||||||||||||||
90 | lässigkeit | ||||||||||||||||||
Estermenge | 88 | % | |||||||||||||||||
85 | 90 | ||||||||||||||||||
(Gew.-%) | 90 | 16 | |||||||||||||||||
0,2 | 90 | ||||||||||||||||||
0,5 | |||||||||||||||||||
1,0 | 90 | ||||||||||||||||||
2,0 | 89 | ||||||||||||||||||
3,0 | 89 | ||||||||||||||||||
4,0 | 88 | ||||||||||||||||||
5,0 | |||||||||||||||||||
Estermenge | |||||||||||||||||||
(Gew.-%) | |||||||||||||||||||
0,2 | |||||||||||||||||||
0,5 | |||||||||||||||||||
1,0 | |||||||||||||||||||
2,0 | |||||||||||||||||||
3,0 | |||||||||||||||||||
4,0 | |||||||||||||||||||
5,0 | |||||||||||||||||||
7,5 | |||||||||||||||||||
Polydimethylsiloxancopolymer mit Neopcntyiglykolmeihacrylat
bslermenge | II | Lichtdurch- Dehnung | % | Benetzung | Antistat. | Ester II | 1.4-Butandioldimethacry lat | annehmbar | Antistat. | H2O |
0,5 | lässigkeit | Eigensch. | Dehnung Benetzung | gut | Eigensch. | Absorption | ||||
(Gew.-"/!,) | 1,0 | % | gut | % | ||||||
0,2 | 1,0 | klar | schlecht | % | gut | |||||
0,5 | 2,0 | 90 | schlecht | 45 | ||||||
1,0 | 1,0 | 90 | schlecht | annehmbar | 40 | |||||
2,0 | 90 | annehmbar | gut | 40 | ||||||
3,0 | 90 | annehmbar | gut | 40 | ||||||
4,0 | 90 | annehmbar | gut | |||||||
5,0 | 90 | ausgezeichnet | gut | |||||||
7,5 | 90 | gut | ||||||||
10,0 | 90 | gut | ||||||||
Beispiel 11 | ||||||||||
Polydimethylsiloxanterpolymer mit Ester I 2-Hydroxypropylmethacrylat | ||||||||||
Kstcrmcnge | H2O | |||||||||
(Gew.-%) | Absorption | |||||||||
I | % | |||||||||
0,5 | ||||||||||
1,0 | ||||||||||
2,0 | ||||||||||
1,0 | ||||||||||
3,0 | ||||||||||
und 1 | ||||||||||
Lichtdurch | ||||||||||
lässigkeit | ||||||||||
% | ||||||||||
90 | ||||||||||
90 | ||||||||||
90 | ||||||||||
90 | ||||||||||
Schleier | ||||||||||
II | Beispiel 12 | Dehnung Benetzung Antistat. | % | H2O | |
0,5 | Polydimethylsiloxanterpolymer mit Ester I 2-Hydroxypropylmethacrylat | Eigensch. | 40 annehmbar | Absorption | |
1,0 | und Ester II 1.4-Butandioldiacrylat | 38 gut | % | ||
listermenge | 1,0 | Lichtdurch | 38 gut | ||
(GCW.-%) | 2,0 | lässigkeit | |||
1 | 1,0 | % | |||
0,5 | 90 | ||||
1,0 | 89 | ||||
2,0 | 88 | ||||
1,0 | Schleier | ||||
3,0 | Schleier | ||||
0,5 | 0,5 | 91 | 50 | gut |
ι,ο | ι,ο | 91 | 48 | gut |
2,0 | 1,0 | 91 | 45 | gut |
ι,ο | 2,0 | 90 | 45 | gut |
3,0 | 2,0 | leichter Schleier | 40 | gut |
2,0 | 3,0 | 86 | 40 | gut |
Linse | Anmerkung | Ester Nr. | Gew.-% |
Nr. | (aus | ||
Tabelle 1) | |||
1 | 9 | 1,0 | |
2 | 10 | 1,0 | |
3 | 7 | 1,0 | |
Terpolymer | |||
1 | 1,0 | ||
4 | 6 | 3,5 | |
Terpolymer | |||
1 | 1,0 | ||
5 | 6 | 5,0 | |
6 | 6 | 4,0 | |
7 | 6 | 3,0 | |
8 | 6 | 2,0 | |
9 | 6 | 7,0 | |
10 | 6 | 3,0 | |
11 | 6 | 1,0 | |
12 | 1 | 1,0 | |
13 | 1 | 1,0 | |
14 | 1 | 1,0 | |
15 | 1 | 1,0 | |
Terpolymer | |||
7 | 1,0 | ||
16 | 7 | 1,0 | |
17 | 3 | 1,0 | |
18 | 4 | 1,0 | |
19 | 5 | 1,0 |
Linse | Anmerkung | lister Nr. | Uew.-'V·. |
Nr. | (au- | ||
Tabelle I) | |||
20 | 1 | 1,0 | |
21 | 6 | 1,0 | |
Terpolymer | |||
1 | 1,0 | ||
22 | 6 | 1,0 | |
23 | 1 | 1,0 | |
Terpolymer | |||
8 | 1,0 | ||
24 | 8 | 1,0 | |
25 | 10 | 2,0 | |
26 | 9 | 2,0 | |
27 | 10 | 3,0 | |
Hierzu 6 Blatt | Zeichnungen |
Claims (1)
ίο c) 1.6-Hexandioldimethacrylat,
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/973,818 US4245069A (en) | 1978-12-28 | 1978-12-28 | Polysiloxane composition |
Publications (1)
Publication Number | Publication Date |
---|---|
DE2954176C2 true DE2954176C2 (de) | 1986-06-12 |
Family
ID=25521255
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE19792941264 Ceased DE2941264A1 (de) | 1978-12-28 | 1979-10-11 | Polymeres fuer kontaktlinsen u.dgl., kontaktlinse und verfahren zur herstellung einer solchen |
DE2954176A Expired DE2954176C2 (de) | 1978-12-28 | 1979-10-11 | Kontaktlinse |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE19792941264 Ceased DE2941264A1 (de) | 1978-12-28 | 1979-10-11 | Polymeres fuer kontaktlinsen u.dgl., kontaktlinse und verfahren zur herstellung einer solchen |
Country Status (6)
Country | Link |
---|---|
US (1) | US4245069A (de) |
CA (1) | CA1134983A (de) |
CH (1) | CH648049A5 (de) |
DE (2) | DE2941264A1 (de) |
FR (1) | FR2445353B1 (de) |
GB (1) | GB2039932A (de) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4423195A (en) * | 1976-04-15 | 1983-12-27 | Danker Laboratories, Inc. | Ocular membrane and method for preparation thereof |
EP0076131B1 (de) * | 1981-09-28 | 1986-04-09 | Hitachi, Ltd. | Feuchtigkeitssensor und Verfahren zur Herstellung eines Feuchtigkeitssensors |
US4395496A (en) * | 1981-11-16 | 1983-07-26 | Uco Optics, Inc. | Cured cellulose ester, method of curing same, and use thereof |
US4616045A (en) * | 1983-06-23 | 1986-10-07 | Gbf, Inc. | Process of preparing an oxygen permeable, styrene based, contact lens material |
US4528301A (en) * | 1983-06-23 | 1985-07-09 | Gbf, Inc. | Oxygen permeable, styrene based, contact lens material |
DE3440652A1 (de) * | 1984-11-07 | 1986-05-07 | Schott Glaswerke, 6500 Mainz | Optische formkoerper |
US20050021137A1 (en) * | 1987-08-24 | 2005-01-27 | Blake Larry W. | Aspheric soft lens |
US5244981A (en) * | 1990-04-10 | 1993-09-14 | Permeable Technologies, Inc. | Silicone-containing contact lens polymers, oxygen permeable contact lenses and methods for making these lenses and treating patients with visual impairment |
US5314960A (en) * | 1990-04-10 | 1994-05-24 | Permeable Technologies, Inc. | Silicone-containing polymers, oxygen permeable hydrophilic contact lenses and methods for making these lenses and treating patients with visual impairment |
US5371147A (en) * | 1990-10-11 | 1994-12-06 | Permeable Technologies, Inc. | Silicone-containing acrylic star polymers, block copolymers and macromonomers |
US5158717A (en) * | 1990-11-27 | 1992-10-27 | Bausch & Lomb Incorporated | Method of molding shaped polymeric articles |
DE4213217C2 (de) * | 1992-04-22 | 1999-11-25 | Geesthacht Gkss Forschung | Membran auf Basis von Pfropfcopolymeren, Pfropfcopolymene und Verfahren zur Herstellung |
US5760100B1 (en) | 1994-09-06 | 2000-11-14 | Ciba Vision Corp | Extended wear ophthalmic lens |
US7468398B2 (en) * | 1994-09-06 | 2008-12-23 | Ciba Vision Corporation | Extended wear ophthalmic lens |
US6467903B1 (en) * | 2000-03-31 | 2002-10-22 | Ocular Sciences, Inc. | Contact lens having a uniform horizontal thickness profile |
US7628485B2 (en) * | 2000-03-31 | 2009-12-08 | Coopervision International Holding Company, Lp | Contact lens having a uniform horizontal thickness profile |
US6774178B2 (en) * | 2001-01-05 | 2004-08-10 | Novartis Ag | Tinted, high Dk ophthalmic molding and a method for making same |
RU2555704C2 (ru) * | 2009-09-15 | 2015-07-10 | Новартис Аг | Преполимеры, применимые для изготовления поглощающих ультрафиолетовое излучение контактных линз |
PT2598937T (pt) | 2010-07-30 | 2016-10-04 | Novartis Ag | Pré-polímeros de polissiloxano anfifílicos e suas utilizações |
NZ606787A (en) | 2010-10-06 | 2014-11-28 | Novartis Ag | Water-processable silicone-containing prepolymers and uses thereof |
US8835525B2 (en) | 2010-10-06 | 2014-09-16 | Novartis Ag | Chain-extended polysiloxane crosslinkers with dangling hydrophilic polymer chains |
US8993651B2 (en) | 2010-10-06 | 2015-03-31 | Novartis Ag | Polymerizable chain-extended polysiloxanes with pendant hydrophilic groups |
US20130204364A1 (en) * | 2010-10-18 | 2013-08-08 | University Of Utah Research Foundation | Vision correction system |
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GB1068020A (en) * | 1965-03-12 | 1967-05-10 | Ass Elect Ind | Silicone elastomers |
DE2713444A1 (de) * | 1976-04-15 | 1977-11-03 | Covington W S | Okularmembran, verfahren und zusammensetzung fuer die herstellung derselben |
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US2560498A (en) * | 1948-08-17 | 1951-07-10 | Corning Glass Works | Copolymeric siloxane elastomers and methods of producing them |
BE553159A (de) * | 1955-12-05 | |||
US2976576A (en) * | 1956-04-24 | 1961-03-28 | Wichterle Otto | Process for producing shaped articles from three-dimensional hydrophilic high polymers |
US2970150A (en) * | 1957-12-17 | 1961-01-31 | Union Carbide Corp | Processes for the reaction of silanic hydrogen-bonded siloxanes with unsaturated organic compounds with a platinum catalyst |
US3228741A (en) * | 1962-06-29 | 1966-01-11 | Mueller Welt Contact Lenses In | Corneal contact lens fabricated from transparent silicone rubber |
BE756792A (fr) * | 1969-09-29 | 1971-03-29 | Stauffer Wacker Silicone Corp | Poly-organosiloxanes modifies et leur preparation |
CA939443A (en) * | 1970-09-08 | 1974-01-01 | Dow Corning Corporation | Siloxane-acrylate copolymers |
US3663650A (en) * | 1970-12-28 | 1972-05-16 | Gen Electric | Substantially transparent polydimethylsiloxane - polyalkylmethacrylate compositions and method for making same |
NZ177276A (en) * | 1974-05-06 | 1978-04-03 | Bausch & Lomb | Separated interpenetrating hydrophilic and hydrophobic polymeric network: contact lens |
US4182723A (en) * | 1976-04-15 | 1980-01-08 | Permavision | Ocular membrane and method for preparation thereof |
FR2365606A2 (fr) * | 1976-09-27 | 1978-04-21 | Bausch & Lomb | Corps solide forme d'un polymere a reseaux a interpenetration simultanee et procede pour sa production |
US4136250A (en) * | 1977-07-20 | 1979-01-23 | Ciba-Geigy Corporation | Polysiloxane hydrogels |
-
1978
- 1978-12-28 US US05/973,818 patent/US4245069A/en not_active Expired - Lifetime
-
1979
- 1979-10-11 DE DE19792941264 patent/DE2941264A1/de not_active Ceased
- 1979-10-11 DE DE2954176A patent/DE2954176C2/de not_active Expired
- 1979-10-29 FR FR7926743A patent/FR2445353B1/fr not_active Expired
- 1979-12-18 CA CA000342119A patent/CA1134983A/en not_active Expired
- 1979-12-21 GB GB7944190A patent/GB2039932A/en not_active Withdrawn
- 1979-12-28 CH CH11526/79A patent/CH648049A5/de not_active IP Right Cessation
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
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GB1068020A (en) * | 1965-03-12 | 1967-05-10 | Ass Elect Ind | Silicone elastomers |
DE2713444A1 (de) * | 1976-04-15 | 1977-11-03 | Covington W S | Okularmembran, verfahren und zusammensetzung fuer die herstellung derselben |
Also Published As
Publication number | Publication date |
---|---|
DE2941264A1 (de) | 1980-07-17 |
CH648049A5 (de) | 1985-02-28 |
FR2445353A1 (fr) | 1980-07-25 |
CA1134983A (en) | 1982-11-02 |
US4245069A (en) | 1981-01-13 |
GB2039932A (en) | 1980-08-20 |
FR2445353B1 (fr) | 1986-04-18 |
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