DE2952373A1 - Verfahren zur bildung eines isolierten immunologischen lectin-konjugates - Google Patents

Verfahren zur bildung eines isolierten immunologischen lectin-konjugates

Info

Publication number
DE2952373A1
DE2952373A1 DE19792952373 DE2952373A DE2952373A1 DE 2952373 A1 DE2952373 A1 DE 2952373A1 DE 19792952373 DE19792952373 DE 19792952373 DE 2952373 A DE2952373 A DE 2952373A DE 2952373 A1 DE2952373 A1 DE 2952373A1
Authority
DE
Germany
Prior art keywords
lectin
sugar
conjugate
insolubilized
component
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19792952373
Other languages
German (de)
English (en)
Inventor
Albert E Chu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
E-Y Laboratories Inc
Original Assignee
E-Y Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by E-Y Laboratories Inc filed Critical E-Y Laboratories Inc
Publication of DE2952373A1 publication Critical patent/DE2952373A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/385—Haptens or antigens, bound to carriers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/44—Antibodies bound to carriers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/961—Chemistry: molecular biology and microbiology including a step of forming, releasing, or exposing the antigen or forming the hapten-immunogenic carrier complex or the antigen per se
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/827—Lectins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
DE19792952373 1978-12-26 1979-12-24 Verfahren zur bildung eines isolierten immunologischen lectin-konjugates Withdrawn DE2952373A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/972,921 US4371515A (en) 1978-12-26 1978-12-26 Method for forming an isolated lectin-immunological conjugate

Publications (1)

Publication Number Publication Date
DE2952373A1 true DE2952373A1 (de) 1980-07-10

Family

ID=25520293

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19792952373 Withdrawn DE2952373A1 (de) 1978-12-26 1979-12-24 Verfahren zur bildung eines isolierten immunologischen lectin-konjugates

Country Status (3)

Country Link
US (1) US4371515A (https=)
JP (1) JPS5593064A (https=)
DE (1) DE2952373A1 (https=)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0033437A1 (de) * 1980-02-02 1981-08-12 MERCK PATENT GmbH Verfahren und Mittel zur Bestimmung einer Komponente aus einer Gruppe bestehend aus spezifisch bindende Rezeptoren und Substanzen, die von diesen Rezeptoren spezifisch gebunden werden können
EP0041426A1 (fr) * 1980-05-22 1981-12-09 Institut Pasteur Produit de couplage entre une lectine et un ligand spécifique, obtention et application dans le domaine biologique
EP0043359A3 (en) * 1980-06-30 1982-01-20 Pharmacia Diagnostics Ab Determination of terminal saccharide groups in glycoprotein
EP0089939A1 (en) * 1982-03-22 1983-09-28 BioCarp AB Compositions for therapeutic or diagnostic use containing oligosaccharides
EP0177191A1 (en) * 1984-09-05 1986-04-09 Serono Diagnostics Partners (A Massachusetts Limited Partnership) Methods of assay
AT382080B (de) * 1981-10-01 1987-01-12 Otsuka Pharma Co Ltd Verfahren zur herstellung von glykoverwandtem antigen
EP0123300A3 (en) * 1983-04-20 1988-01-20 Enzo Biochem, Inc. Complexing of biologically active or functional compounds and methods of preparing and utilizing same
EP0628315A1 (en) * 1986-03-20 1994-12-14 Dana-Farber Cancer Institute, Inc. Lectin complex and probe and method for making same

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4450104A (en) * 1980-09-30 1984-05-22 Cutter Laboratories, Inc. Water insoluble gel matrix containing lectin bound to antithrombin
US4446314A (en) * 1980-09-30 1984-05-01 Cutter Laboratories, Inc. Fractionation of heparin
IL63855A (en) * 1981-09-16 1984-10-31 Teva Pharma Method and kit for detecting pregnancy
US4530900A (en) * 1982-09-13 1985-07-23 Seragen Diagnostics Inc. Soluble insoluble polymers in enzymeimmunoassay
FR2534030A1 (fr) * 1982-10-01 1984-04-06 Pasteur Institut Procede de detection et de dosage d'une substance biologique par erythroadsorption
US4470967A (en) * 1982-10-05 1984-09-11 Iowa State University Research Foundation Lectin-containing anti-viral vaccines for domestic animals and method of preparation
US4608246A (en) * 1983-03-10 1986-08-26 Immucor, Inc. Testing for a blood group immunological reaction
FI852545A7 (fi) * 1984-06-29 1985-12-30 Ortho Diagnostic Systems Inc Vasta-aine-lektiini kerrosanalyysi.
US4737453A (en) * 1984-12-12 1988-04-12 Immunomedics, Inc. Sandwich immunoassay utilizing a separation specific binding substance
US4780409A (en) * 1985-05-02 1988-10-25 Genetic Systems Corporation Thermally induced phase separation immunoassay
US4935339A (en) * 1985-05-07 1990-06-19 Nichols Institute Diagnostics Delayed solid phase immunologic assay
US5395924A (en) * 1986-03-20 1995-03-07 Dana-Farber Cancer Institute, Inc. Blocked lectins; methods and affinity support for making the same using affinity ligands; and method of killing selected cell populations having reduced non-selective cytotoxicity
US5239062A (en) * 1986-03-20 1993-08-24 Dana-Farber Cancer Institute, Inc. Blocked lectins, methods and affinity support for making same using affinity ligands, and method of killing selected cell populations having reduced nonselective cytotoxicity
US5173407A (en) * 1986-12-16 1992-12-22 Konica Corporation Method for measuring glycosyltransferase
US5494800A (en) * 1987-01-29 1996-02-27 Cytosignet, Inc. Analyte detection in particulate-containing samples
JPH0734015B2 (ja) * 1988-04-25 1995-04-12 和光純薬工業株式会社 微量成分の新規測定法
DE3900639A1 (de) * 1988-12-23 1990-06-28 Boehringer Mannheim Gmbh Verfahren zum nachweis von kohlenhydrathaltigen verbindungen und dazu geeignetes reagenz
US5474772A (en) * 1989-08-02 1995-12-12 Cobe Laboratories, Inc. Method of treatment with medical agents
US6165710A (en) * 1989-10-23 2000-12-26 Robinson; James E. Method for immobilizing viral glycoproteins for use in solid-phase immunoassays
US5252743A (en) * 1989-11-13 1993-10-12 Affymax Technologies N.V. Spatially-addressable immobilization of anti-ligands on surfaces
EP0502060A4 (en) * 1989-11-13 1993-05-05 Affymax Technologies N.V. Spatially-addressable immobilization of anti-ligands on surfaces
JP2994739B2 (ja) * 1990-11-29 1999-12-27 和光純薬工業株式会社 微量成分の迅速測定方法
SE9100142L (sv) 1991-01-17 1992-07-18 Bengt Sandberg En metod och ett system foer foerbaettrad in vivo reducering av diagnostiska och/eller terapeutiska substanser medelst extrakorporeal borttagning, och anvaendandet av naemnda substanser foer detta aendamaal
US5766552A (en) * 1993-04-20 1998-06-16 Actimed Laboratories, Inc. Apparatus for red blood cell separation
US5660798A (en) * 1993-04-20 1997-08-26 Actimed Laboratories, Inc. Apparatus for red blood cell separation
US5652148A (en) * 1993-04-20 1997-07-29 Actimed Laboratories, Inc. Method and apparatus for red blood cell separation
US6103237A (en) * 1993-07-22 2000-08-15 Hybritech Incorporated Stable variant hK2 polypeptide
US5516639A (en) * 1993-07-22 1996-05-14 Mayo Foundation For Medical Education And Research Antibodies specific for human prostate glandular kallkrein
US20040259113A1 (en) * 1993-07-22 2004-12-23 Mayo Foundation For Medical Education And Research, Hybritech Incorporated Method for detection of metastatic prostate cancer
EP0653640B1 (en) * 1993-11-16 2000-01-19 Wako Pure Chemical Industries Ltd Process for separating and measuring glycoprotein
WO1995030758A1 (en) * 1994-05-10 1995-11-16 Mayo Foundation For Medical Education And Research Recombinant hk2 polypeptide
US6479263B1 (en) 1996-11-14 2002-11-12 Baylor College Of Medicine Method for detection of micrometastatic prostate cancer
AU8259798A (en) 1997-06-20 1999-01-04 George G Klee Method for detection of breast cancer
US6150123A (en) * 1998-09-03 2000-11-21 Centre Integre De Recherches Biocliniques Sur Le Sida (Cirbs) Affinity biotinylation
US20080280310A1 (en) * 2007-05-09 2008-11-13 Louis Panagopoulos Testing for Blood Group Immunological Reaction Without the Use of Anti-Human Globulin
WO2021235521A1 (ja) 2020-05-22 2021-11-25 キッコーマン株式会社 容器詰組成物及びその使用並びに容器詰加工食品

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3994870A (en) * 1974-01-31 1976-11-30 The Community Blood Council Of Greater New York, Inc. Purification of hepatitis B surface antigen
US4041146A (en) * 1975-05-01 1977-08-09 General Electric Company Method for detection of biological particles
US4289747A (en) * 1978-12-26 1981-09-15 E-Y Laboratories, Inc. Immunological determination using lectin

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0033437A1 (de) * 1980-02-02 1981-08-12 MERCK PATENT GmbH Verfahren und Mittel zur Bestimmung einer Komponente aus einer Gruppe bestehend aus spezifisch bindende Rezeptoren und Substanzen, die von diesen Rezeptoren spezifisch gebunden werden können
EP0041426A1 (fr) * 1980-05-22 1981-12-09 Institut Pasteur Produit de couplage entre une lectine et un ligand spécifique, obtention et application dans le domaine biologique
EP0043359A3 (en) * 1980-06-30 1982-01-20 Pharmacia Diagnostics Ab Determination of terminal saccharide groups in glycoprotein
WO1982000204A1 (en) * 1980-06-30 1982-01-21 Cerven E Lectin immunoassay for the determination of terminal saccharide groups in glycoprotein
AT382080B (de) * 1981-10-01 1987-01-12 Otsuka Pharma Co Ltd Verfahren zur herstellung von glykoverwandtem antigen
EP0089939A1 (en) * 1982-03-22 1983-09-28 BioCarp AB Compositions for therapeutic or diagnostic use containing oligosaccharides
EP0123300A3 (en) * 1983-04-20 1988-01-20 Enzo Biochem, Inc. Complexing of biologically active or functional compounds and methods of preparing and utilizing same
EP0177191A1 (en) * 1984-09-05 1986-04-09 Serono Diagnostics Partners (A Massachusetts Limited Partnership) Methods of assay
EP0628315A1 (en) * 1986-03-20 1994-12-14 Dana-Farber Cancer Institute, Inc. Lectin complex and probe and method for making same

Also Published As

Publication number Publication date
US4371515A (en) 1983-02-01
JPS6343710B2 (https=) 1988-09-01
JPS5593064A (en) 1980-07-15

Similar Documents

Publication Publication Date Title
DE2952373A1 (de) Verfahren zur bildung eines isolierten immunologischen lectin-konjugates
DE69325747T2 (de) Schnelle, verbesserte Immunoassays durch Verwendung einer neuen Immunkomplextransfer-Technik
DE2951678A1 (de) Immunologische bestimmung mit hilfe von lectin
DE3650513T2 (de) Verzögerter immunologischer Test in fester Phase
EP0023989B1 (de) Enzym-Immuntest zum Nachweis von Erreger-spezifischen Antikörpern und Testsatz für die Durchführung dieses Tests
DE2654723C2 (de) Magnetischer Festphasenträger für immunologische Bestimmungen sowie ein Verfahren zu dessen Herstellung
DE2743444C3 (de) Immunchemisches Meßverfahren und Reagens zu seiner Durchführung
DE2953449A1 (de) Verfahren und ausruestung fuer die enzym-immunoassay von biologischen substanzen
DE2902676A1 (de) Immunoassays unter verwendung von f(ab') tief 2 -untergruppen
DE2744835B2 (de) Immunchemisches Meßverfahren
DE2206103B2 (de) Verfahren zum Nachweisen und Bestimmen einer Komponente der Reaktion zwischen spezifisch bindenden Proteinen und den Substanzen, die von diesen Proteinen spezifisch gebunden werden
DE2744836A1 (de) Immunchemisches messverfahren
EP0544869B2 (de) Immunologisches bestimmungsverfahren zur bestimmung von antikörpern in biologischen flüssigkeiten sowie kit zur durchführung des verfahrens
DE19524572A1 (de) Verfahren zur Herstellung eines synthetischen Kalibrators für den Einsatz in Immunoassays, bestehend aus den Analyten oder Teilsequenzen davon, die an inerten Trägermoleküle konjugiert sind
EP0943098B1 (de) Rezeptorbindungsassay zum nachweis von tsh-rezeptor-autoantikörpern
DE69204718T2 (de) CA-195 ähnliches immunreaktives Antigen von menschlicher Amnionflüssigkeit.
EP0291086A2 (de) Verfahren zur Bestimmung eines Antikörpers in menschlichen Körperflüssigkeiten
DE69619257T2 (de) Die konjugation von liganden an immobilisierte proteine in einem organischen lösungsmittel
EP0379216B1 (de) Verfahren und Reagenz zur Bestimmung von immunologisch nachweisbaren Substanzen
DE3877032T2 (de) Diagnostischer immunoassay fuer digoxin mit festphasetrennung.
DE4218257A1 (de) Verfahren zur immunchemischen Bestimmung eines Analyten
DE69229960T2 (de) Agglutierungsassays und kolloide farbstoffe verwendende testsätze
DE2533701A1 (de) Immunologische diagnoseprodukte
DE2616984B2 (de) Verfahren zur Isolierung und Reinigung eines plazentenspezifischen Glycoproteins
DE2905154C2 (https=)

Legal Events

Date Code Title Description
8139 Disposal/non-payment of the annual fee