DE2833940C2 - - Google Patents

Info

Publication number
DE2833940C2
DE2833940C2 DE2833940A DE2833940A DE2833940C2 DE 2833940 C2 DE2833940 C2 DE 2833940C2 DE 2833940 A DE2833940 A DE 2833940A DE 2833940 A DE2833940 A DE 2833940A DE 2833940 C2 DE2833940 C2 DE 2833940C2
Authority
DE
Germany
Prior art keywords
sam
monosulfate
disulfate
solution
sulfuric acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE2833940A
Other languages
German (de)
English (en)
Other versions
DE2833940A1 (de
Inventor
Toshihisa Kawahara
Goro Choshi Chiba Jp Motoki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yamasa Shoyu Kk Choshi Chiba Jp
Original Assignee
Yamasa Shoyu Kk Choshi Chiba Jp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP9255277A external-priority patent/JPS5428808A/ja
Priority claimed from JP12153577A external-priority patent/JPS5455598A/ja
Priority claimed from JP15885677A external-priority patent/JPS54109998A/ja
Priority claimed from JP6159778A external-priority patent/JPS54154774A/ja
Application filed by Yamasa Shoyu Kk Choshi Chiba Jp filed Critical Yamasa Shoyu Kk Choshi Chiba Jp
Publication of DE2833940A1 publication Critical patent/DE2833940A1/de
Application granted granted Critical
Publication of DE2833940C2 publication Critical patent/DE2833940C2/de
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16Purine radicals
    • GPHYSICS
    • G11INFORMATION STORAGE
    • G11BINFORMATION STORAGE BASED ON RELATIVE MOVEMENT BETWEEN RECORD CARRIER AND TRANSDUCER
    • G11B27/00Editing; Indexing; Addressing; Timing or synchronising; Monitoring; Measuring tape travel

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE19782833940 1977-08-03 1978-08-02 S-adenosyl-l-methionin enthaltende praeparate, welche gegen eine zersetzung der wirkstoff-komponente stabilisiert sind, und herstellungsverfahren fuer diese praeparate Granted DE2833940A1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP9255277A JPS5428808A (en) 1977-08-03 1977-08-03 Composition containing s-adenoyl-l-methionine and its preparation
JP12153577A JPS5455598A (en) 1977-10-12 1977-10-12 Composition containing s-adensoyl-l-methionine and its preparation
JP15885677A JPS54109998A (en) 1977-12-30 1977-12-30 Composition containing s-adenosyl-l-methionine and its preparation
JP6159778A JPS54154774A (en) 1978-05-25 1978-05-25 S-adenosyl-l-methionine-containing composition and its preparation

Publications (2)

Publication Number Publication Date
DE2833940A1 DE2833940A1 (de) 1979-02-15
DE2833940C2 true DE2833940C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1987-11-19

Family

ID=27464061

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19782833940 Granted DE2833940A1 (de) 1977-08-03 1978-08-02 S-adenosyl-l-methionin enthaltende praeparate, welche gegen eine zersetzung der wirkstoff-komponente stabilisiert sind, und herstellungsverfahren fuer diese praeparate

Country Status (4)

Country Link
US (1) US4242505A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE2833940A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB2001976B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IT (1) IT1106865B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2064523B (en) * 1979-12-04 1983-06-29 Kanegafuchi Chemical Ind Stable composition of s-adenosyl-l-methionine
IT1137892B (it) * 1981-08-24 1986-09-10 Bioresearch Srl Sali stabili della s-adenosilmetionina,processo per la loro preparazione e composizioni terapeutiche che li comprendono come principio attivo
IT1139974B (it) * 1981-09-11 1986-09-24 Bioresearch Srl Derivati della s-adenosilmetionina,processo per la preparazione e composizioni terapeutiche che li contengono come principio attivo
IT1169773B (it) * 1983-08-24 1987-06-03 Bioresearch Spa Processo per la produzione di sali stabili della solfo-adenosil-l-metionina
US4794174A (en) * 1987-02-10 1988-12-27 Southern Research Institute 5'deoxy-5'-substituted adenosines
US5180714A (en) * 1990-10-31 1993-01-19 Health Research, Inc. Adenosine compounds for the treatment of diseases caused by parasitic protozoa
JPH06192109A (ja) * 1992-09-04 1994-07-12 Fuji Kagaku Kogyo Kk 抗腫瘍効果増強剤
DE19632823C1 (de) * 1996-08-14 1997-11-20 Symbio Herborn Group Gmbh & Co Komplexe zwischen S-(+)-Adenosylmethionin und 3'-Azido-2',3'-didesoxynucleosid als potente Inhibitoren der HIV-Replikation
US8642581B1 (en) 2000-02-11 2014-02-04 Brian D. Halevie-Goldman Compositions and methods for the production of S-adenosylmethionine within the body
US6759395B2 (en) 2000-12-18 2004-07-06 Orchid Chemicals & Pharmaceuticals, Ltd. Soft-gelatin capsule comprising S-adenosylmethionine and a method for producing the same
US20040116351A1 (en) * 2002-12-06 2004-06-17 Fast Balance, Inc. Method for enhancing the natural reward system for exercise
EP1758596B9 (en) * 2004-05-26 2010-09-15 Inotek Pharmaceuticals Corporation Purine derivatives as adenosine a1 receptor agonists and methods of use thereof
EP1962597A4 (en) * 2005-11-30 2008-12-17 Inotek Pharmaceuticals Corp PURINE DERIVATIVES AND METHOD OF USE
SG182285A1 (en) 2010-01-11 2012-08-30 Inotek Pharmaceuticals Corp Combination, kit and method of reducing intraocular pressure
BR112012023749A2 (pt) 2010-03-26 2016-08-23 Inotek Pharmaceuticals Corp método para reduzir a pressão intraocular em humanos utilizando n6-ciclopentiladenosina (cpa), derivados de cpa ou pró-fármacos desses
CN104093731B (zh) 2012-01-26 2017-05-24 伊诺泰克制药公司 [(2r,3s,4r,5r)‑5‑(6‑(环戊基氨基)‑9h‑嘌呤‑9‑基)‑3,4‑二羟基四氢呋喃‑2‑基)]甲基硝酸酯的无水多晶型物及其制备方法
WO2014113609A1 (en) 2013-01-16 2014-07-24 Hebert Sam-E Llc Stable indole-3-propionate salts of s-adenosyl-l-methionine
NZ630759A (en) 2013-03-15 2017-07-28 Inotek Pharmaceuticals Corp Ophthalmic formulations comprising an a1 agonist

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE39517B1 (en) * 1973-06-27 1978-10-25 Bioresearch Sas Double salts of s-adenosyl-l-methhionine
AR221676A1 (es) * 1974-07-12 1981-03-13 Bioresearch Sas Procedimiento para la preparacion de sales estables sulfonicas y/o sulfuricas de la s-adenosil-l-metionina,particularmente utiles como donadores especificos de metilo para las reacciones bioquimicas de transferencia del grupo ch3;asi como tambien las reacciones fundamentales en el metabolismo lipilico,protilico y glucidico
DE2646269A1 (de) * 1975-10-16 1977-04-28 Yamasa Shoyu Kk Stabilisierte s-adenosyl-l-methionin- zubereitung und verfahren zur herstellung derselben

Also Published As

Publication number Publication date
DE2833940A1 (de) 1979-02-15
GB2001976B (en) 1982-03-10
IT1106865B (it) 1985-11-18
GB2001976A (en) 1979-02-14
IT7850578A0 (it) 1978-08-02
US4242505A (en) 1980-12-30

Similar Documents

Publication Publication Date Title
DE2833940C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE2430999C2 (de) Neue Doppelsalze von S-Adenosyl-L-methionin mit Schwefel- und p-Toluolsulfonsäure, Verfahren zu ihrer Herstellung und Arzneimittel
DE3612636C2 (de) Nucleosid-Phospholipid-Komplexe
DE2336401C3 (de) Tri-p-toluolsulfonat von S-Adenosyl-L-methionin, Verfahren zu dessen Herstellung und therapeutische Mittel, die es enthalten
EP0056265B1 (de) 5'-Ester von Pyrimidinnucleosiden mit antiviraler Wirksamkeit, Verfahren zur Herstellung und daraus hergestellte Arzneimittel
DE2530898A1 (de) Sulfonsaeuresalze von s-adenosylmethionin, verfahren zu deren herstellung und die genannten salze enthaltende therapeutische zusammensetzungen
DE3045786A1 (de) Stabile s-adenosyl-l-methionin-formulierung und verfahren zu ihrer herstellung
CH634310A5 (de) Verfahren zur herstellung neuer pyrimidonderivate.
DE1803978C2 (de) Verfahren zur Gewinnung von S-Adenosyl-l-methionin und S-Adenosyl-l-ethionin
DE69902624T2 (de) Ein kristall von diuridine tetraphosphat oder ein solches salz und verfahren zu seiner herstellung, verfahren und herstellung der vorgenannten zusammensetzung
CH635344A5 (en) Process for the preparation of d,l-5-methyltetrahydrofolic acid and its salts
DE60021629T2 (de) Dinukleotid-Kristalle
DE2546073A1 (de) Nucleotid-derivate und verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln
DE3044740A1 (de) Nucleosidderivate, ihre herstellung und pharmazeutische mittel
DE2646269A1 (de) Stabilisierte s-adenosyl-l-methionin- zubereitung und verfahren zur herstellung derselben
DE2119964B2 (de) Methyl-n-(n'-methyl-n'-nitrosocarbamoyl)-d-glycosaminid und verfahren zu dessen herstellung
CH620362A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE69717568T2 (de) S-(+)-Adenosylmethionine und 3'-Azido-2',3'-Dideoxy-Nukleosid-Komplexe als potente Inhibitoren von HIV-Replikation
DE2059429C2 (de) Verfahren zur Herstellung von Nucleosiddiphosphatestern
DE3141030C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE69107098T2 (de) 2'-Deoxy-2'-Methylidenecytidin-dihydrat, Verfahren zu ihrer Herstellung und Mischmaterial.
DE2945129C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CH467277A (de) Verfahren zur Herstellung von Cobalticorrinoiden
DE1922172B2 (de) In C8 -Stellung modifizierte Purinribofuranosid-3' zu S'-cyclophosphate
DE2125077A1 (de) Substituierte Purinnbofuranosid 3, 5 cyclophosphate und Verfahren zu ihrer Herstellung

Legal Events

Date Code Title Description
8128 New person/name/address of the agent

Representative=s name: JUNG, E., DIPL.-CHEM. DR.PHIL. SCHIRDEWAHN, J., DI

8110 Request for examination paragraph 44
D2 Grant after examination
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee