DE2746383A1 - Neue mikroorganismusmutanten und verwendung derselben bei der herstellung von androst-4-en-3,17-dion - Google Patents

Neue mikroorganismusmutanten und verwendung derselben bei der herstellung von androst-4-en-3,17-dion

Info

Publication number
DE2746383A1
DE2746383A1 DE19772746383 DE2746383A DE2746383A1 DE 2746383 A1 DE2746383 A1 DE 2746383A1 DE 19772746383 DE19772746383 DE 19772746383 DE 2746383 A DE2746383 A DE 2746383A DE 2746383 A1 DE2746383 A1 DE 2746383A1
Authority
DE
Germany
Prior art keywords
steroid
androst
dione
carbon atoms
dsm
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
DE19772746383
Other languages
German (de)
English (en)
Other versions
DE2746383C2 (sk
Inventor
Candice Brenda Biggs
Merle Gene Wovcha
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of DE2746383A1 publication Critical patent/DE2746383A1/de
Application granted granted Critical
Publication of DE2746383C2 publication Critical patent/DE2746383C2/de
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003Androstane derivatives
    • C07J1/0011Androstane derivatives substituted in position 17 by a keto group
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00Preparation of steroids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00Preparation of steroids
    • C12P33/005Degradation of the lateral chains at position 17

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE19772746383 1976-10-22 1977-10-14 Neue mikroorganismusmutanten und verwendung derselben bei der herstellung von androst-4-en-3,17-dion Granted DE2746383A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US73507576A 1976-10-22 1976-10-22

Publications (2)

Publication Number Publication Date
DE2746383A1 true DE2746383A1 (de) 1978-04-27
DE2746383C2 DE2746383C2 (sk) 1987-02-12

Family

ID=24954263

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19772746383 Granted DE2746383A1 (de) 1976-10-22 1977-10-14 Neue mikroorganismusmutanten und verwendung derselben bei der herstellung von androst-4-en-3,17-dion

Country Status (3)

Country Link
JP (2) JPS5356389A (sk)
DE (1) DE2746383A1 (sk)
NL (1) NL189865C (sk)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0008214A1 (en) * 1978-08-07 1980-02-20 The Upjohn Company Microorganisms and their use in producing androst-4-ene-3,17-dione

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL6513718A (sk) * 1965-10-22 1967-04-24
US3684657A (en) * 1970-05-11 1972-08-15 Searle & Co Selective microbiological degradation of steroidal 17-alkyls
US3759791A (en) * 1970-12-10 1973-09-18 Searle & Co Selective microbiological preparation of androst-4-ene-3,17-dione
DE2703645C3 (de) * 1976-03-01 1981-11-12 The Upjohn Co., 49001 Kalamazoo, Mich. Verfahren zur Herstellung eines Gemischs aus Androsta-1,4-dien-3,17-dion und Androst-4-en-3,17-dion

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NICHTS-ERMITTELT *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0008214A1 (en) * 1978-08-07 1980-02-20 The Upjohn Company Microorganisms and their use in producing androst-4-ene-3,17-dione

Also Published As

Publication number Publication date
JPS61205480A (ja) 1986-09-11
JPS6231906B2 (sk) 1987-07-10
NL189865B (nl) 1993-03-16
NL189865C (nl) 1993-08-16
DE2746383C2 (sk) 1987-02-12
JPS5356389A (en) 1978-05-22
JPS6117478B2 (sk) 1986-05-07
NL7711087A (nl) 1978-04-25

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Legal Events

Date Code Title Description
8128 New person/name/address of the agent

Representative=s name: HENKEL, G., DR.PHIL. FEILER, L., DR.RER.NAT. HAENZ

8110 Request for examination paragraph 44
D2 Grant after examination
8364 No opposition during term of opposition