DE2741202A1 - Dinatriumcromoglycat mit besonderer massendichte - Google Patents
Dinatriumcromoglycat mit besonderer massendichteInfo
- Publication number
- DE2741202A1 DE2741202A1 DE19772741202 DE2741202A DE2741202A1 DE 2741202 A1 DE2741202 A1 DE 2741202A1 DE 19772741202 DE19772741202 DE 19772741202 DE 2741202 A DE2741202 A DE 2741202A DE 2741202 A1 DE2741202 A1 DE 2741202A1
- Authority
- DE
- Germany
- Prior art keywords
- disodium cromoglycate
- disodium
- cromoglycate
- granular
- particles
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 title 1
- 229910052708 sodium Inorganic materials 0.000 title 1
- 239000011734 sodium Substances 0.000 title 1
- IMZMKUWMOSJXDT-UHFFFAOYSA-N cromoglycic acid Chemical group O1C(C(O)=O)=CC(=O)C2=C1C=CC=C2OCC(O)COC1=CC=CC2=C1C(=O)C=C(C(O)=O)O2 IMZMKUWMOSJXDT-UHFFFAOYSA-N 0.000 claims description 35
- 229960000265 cromoglicic acid Drugs 0.000 claims description 33
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 16
- 239000002245 particle Substances 0.000 claims description 15
- 239000002775 capsule Substances 0.000 claims description 13
- QXNVGIXVLWOKEQ-UHFFFAOYSA-N Disodium Chemical compound [Na][Na] QXNVGIXVLWOKEQ-UHFFFAOYSA-N 0.000 claims description 5
- 239000000314 lubricant Substances 0.000 claims description 3
- 239000000463 material Substances 0.000 claims description 3
- 238000004519 manufacturing process Methods 0.000 claims description 2
- 238000000034 method Methods 0.000 claims description 2
- 239000003814 drug Substances 0.000 description 7
- 239000008187 granular material Substances 0.000 description 6
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 5
- 229940079593 drug Drugs 0.000 description 5
- 239000002552 dosage form Substances 0.000 description 4
- 238000005469 granulation Methods 0.000 description 3
- 230000003179 granulation Effects 0.000 description 3
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 2
- 239000011362 coarse particle Substances 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000035475 disorder Diseases 0.000 description 2
- 238000009826 distribution Methods 0.000 description 2
- 238000001035 drying Methods 0.000 description 2
- 210000001035 gastrointestinal tract Anatomy 0.000 description 2
- 239000008101 lactose Substances 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 239000008194 pharmaceutical composition Substances 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 208000035285 Allergic Seasonal Rhinitis Diseases 0.000 description 1
- 108010010803 Gelatin Proteins 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 208000009793 Milk Hypersensitivity Diseases 0.000 description 1
- 201000010859 Milk allergy Diseases 0.000 description 1
- 238000013019 agitation Methods 0.000 description 1
- 239000013566 allergen Substances 0.000 description 1
- 208000026935 allergic disease Diseases 0.000 description 1
- 230000000172 allergic effect Effects 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 208000010668 atopic eczema Diseases 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- 238000004040 coloring Methods 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 229940109248 cromoglycate Drugs 0.000 description 1
- -1 e.g. Substances 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 229920000159 gelatin Polymers 0.000 description 1
- 239000008273 gelatin Substances 0.000 description 1
- 239000007903 gelatin capsule Substances 0.000 description 1
- 235000019322 gelatine Nutrition 0.000 description 1
- 235000011852 gelatine desserts Nutrition 0.000 description 1
- 230000008105 immune reaction Effects 0.000 description 1
- 239000000543 intermediate Substances 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 238000005029 sieve analysis Methods 0.000 description 1
- 238000007873 sieving Methods 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/24—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB39619/76A GB1549229A (en) | 1976-09-23 | 1976-09-23 | High density sodium cromoglycate |
| GB4305476 | 1976-10-16 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE2741202A1 true DE2741202A1 (de) | 1978-03-30 |
| DE2741202C2 DE2741202C2 (enrdf_load_stackoverflow) | 1987-09-10 |
Family
ID=26264184
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19772741202 Granted DE2741202A1 (de) | 1976-09-23 | 1977-09-13 | Dinatriumcromoglycat mit besonderer massendichte |
Country Status (8)
| Country | Link |
|---|---|
| JP (1) | JPS5340776A (enrdf_load_stackoverflow) |
| AU (1) | AU508134B2 (enrdf_load_stackoverflow) |
| DE (1) | DE2741202A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2365565A1 (enrdf_load_stackoverflow) |
| IE (1) | IE45690B1 (enrdf_load_stackoverflow) |
| IL (1) | IL52961A (enrdf_load_stackoverflow) |
| NL (1) | NL186219C (enrdf_load_stackoverflow) |
| NZ (1) | NZ185240A (enrdf_load_stackoverflow) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5657540A (en) * | 1979-10-15 | 1981-05-20 | Sanyo Denki Seisakusho:Kk | Fare annunciator for bus provided with controlling function |
| JPS634660Y2 (enrdf_load_stackoverflow) * | 1986-10-02 | 1988-02-06 | ||
| JPH09152290A (ja) * | 1995-11-29 | 1997-06-10 | Sanyo Electric Co Ltd | 吸収式冷凍機 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2535258C2 (de) * | 1974-08-10 | 1993-06-03 | Fisons Plc, Ipswich, Suffolk | Inhalierbares Medikament in Pelletform |
| GB1520247A (en) * | 1974-08-10 | 1978-08-02 | Fisons Ltd | Pelletised medicament formulations |
-
1977
- 1977-09-13 DE DE19772741202 patent/DE2741202A1/de active Granted
- 1977-09-20 FR FR7728250A patent/FR2365565A1/fr active Granted
- 1977-09-20 IL IL52961A patent/IL52961A/xx unknown
- 1977-09-21 AU AU28983/77A patent/AU508134B2/en not_active Expired
- 1977-09-21 IE IE1927/77A patent/IE45690B1/en not_active IP Right Cessation
- 1977-09-22 JP JP11343377A patent/JPS5340776A/ja active Granted
- 1977-09-22 NL NLAANVRAGE7710382,A patent/NL186219C/xx not_active IP Right Cessation
- 1977-09-27 NZ NZ185240A patent/NZ185240A/xx unknown
Non-Patent Citations (3)
| Title |
|---|
| Chem. Abstr. 75, 1971, 3872 * |
| J. Pharm. Sci. 60, 1971, S.1458-1465 * |
| Toxicology Appl. Pharmacol. 17, 1970, S.699-707 * |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2898377A (en) | 1979-03-29 |
| AU508134B2 (en) | 1980-03-13 |
| NL7710382A (nl) | 1978-03-29 |
| NZ185240A (en) | 1979-08-31 |
| FR2365565B1 (enrdf_load_stackoverflow) | 1980-06-06 |
| JPS5340776A (en) | 1978-04-13 |
| JPH0137369B2 (enrdf_load_stackoverflow) | 1989-08-07 |
| IL52961A (en) | 1981-02-27 |
| FR2365565A1 (fr) | 1978-04-21 |
| IL52961A0 (en) | 1977-11-30 |
| NL186219B (nl) | 1990-05-16 |
| NL186219C (nl) | 1990-10-16 |
| IE45690L (en) | 1978-03-23 |
| IE45690B1 (en) | 1982-10-20 |
| DE2741202C2 (enrdf_load_stackoverflow) | 1987-09-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8110 | Request for examination paragraph 44 | ||
| 8125 | Change of the main classification |
Ipc: C07D311/24 |
|
| 8127 | New person/name/address of the applicant |
Owner name: FISONS PLC, IPSWICH, SUFFOLK, GB |
|
| 8128 | New person/name/address of the agent |
Representative=s name: WUESTHOFF, F., DR.-ING. FRHR. VON PECHMANN, E., DI |
|
| D2 | Grant after examination | ||
| 8381 | Inventor (new situation) |
Free format text: TAYLOR, JAMES EDWARD STEVENSON, NEIL ARTHUR, LOUGHBOROUGH, LEICESTERSHIRE, GB |
|
| 8363 | Opposition against the patent | ||
| 8365 | Fully valid after opposition proceedings | ||
| 8380 | Miscellaneous part iii |
Free format text: ES ERFOLGT ERGAENZUNGSDRUCK NACH UNBESCHRAENKTES AUFRECHTERHALTUNG |