IE45690L - High density sodium cromoglycate - Google Patents

High density sodium cromoglycate

Info

Publication number
IE45690L
IE45690L IE771927A IE192777A IE45690L IE 45690 L IE45690 L IE 45690L IE 771927 A IE771927 A IE 771927A IE 192777 A IE192777 A IE 192777A IE 45690 L IE45690 L IE 45690L
Authority
IE
Ireland
Prior art keywords
pref
esp
degrees
water
drying
Prior art date
Application number
IE771927A
Other versions
IE45690B1 (en
Original Assignee
Fisons Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26264184&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IE45690(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB39619/76A external-priority patent/GB1549229A/en
Application filed by Fisons Ltd filed Critical Fisons Ltd
Publication of IE45690L publication Critical patent/IE45690L/en
Publication of IE45690B1 publication Critical patent/IE45690B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/24—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)

Abstract

Disodium cromoglycate (I) of apparent density >0.45g/ml (by BS No. 1460 (1967)) is new. Apparent density is pref. 0.5-0.7, esp. 0.53-0.66 g/ml and (I) is pref. in the form of hard granules. Pref. (I) contains 5, esp. 1 wt. % (partic. 0%) other cpds., except for water. Pref. 20 wt. % particles are of dia. >250 mu and is not >60 wt. % are 60 mu (esp. pref. are 20 wt. % at >200 mu and is not >60 wt. % at 90 mu), and 20% are 60 mu (45 mu). Granular (I) may be prepd. by passing (I) of water content 15-35 (esp. 22-24) wt. % through a sieve (4-30 holes inch), then drying to 5-8 wt. % humidity. Pref. water is added prior to sieving at 2 wt. %/min. (0.5-1.5%), pref. by spraying. Granulation is pref. at 50 degrees C and drying is at 60-100 degrees C esp. 75-85 degrees C. (I) is known for use in treating asthma and gastro-intestinal troubles associated with allergic or immunological reactions. The granular form can be encapsulated, easily without the need for flowing aids (i.e. lactose), lubricants etc. The dosage forms are useful in treating e.g. allergy to milk (at 5-250mg) or hay fever (at 1-10mg). [FR2365565A1]
IE1927/77A 1976-09-23 1977-09-21 High density sodium cromoglycate IE45690B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB39619/76A GB1549229A (en) 1976-09-23 1976-09-23 High density sodium cromoglycate
GB4305476 1976-10-16

Publications (2)

Publication Number Publication Date
IE45690L true IE45690L (en) 1978-03-23
IE45690B1 IE45690B1 (en) 1982-10-20

Family

ID=26264184

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1927/77A IE45690B1 (en) 1976-09-23 1977-09-21 High density sodium cromoglycate

Country Status (8)

Country Link
JP (1) JPS5340776A (en)
AU (1) AU508134B2 (en)
DE (1) DE2741202A1 (en)
FR (1) FR2365565A1 (en)
IE (1) IE45690B1 (en)
IL (1) IL52961A (en)
NL (1) NL186219C (en)
NZ (1) NZ185240A (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5657540A (en) * 1979-10-15 1981-05-20 Sanyo Denki Seisakusho:Kk Fare annunciator for bus provided with controlling function
JPS634660Y2 (en) * 1986-10-02 1988-02-06
JPH09152290A (en) * 1995-11-29 1997-06-10 Sanyo Electric Co Ltd Absorption refrigerating machine

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1520247A (en) * 1974-08-10 1978-08-02 Fisons Ltd Pelletised medicament formulations
DE2535258C2 (en) * 1974-08-10 1993-06-03 Fisons Plc, Ipswich, Suffolk Inhalable drug in pellet form

Also Published As

Publication number Publication date
JPH0137369B2 (en) 1989-08-07
NL186219C (en) 1990-10-16
FR2365565B1 (en) 1980-06-06
JPS5340776A (en) 1978-04-13
AU508134B2 (en) 1980-03-13
AU2898377A (en) 1979-03-29
NZ185240A (en) 1979-08-31
IL52961A (en) 1981-02-27
IE45690B1 (en) 1982-10-20
DE2741202A1 (en) 1978-03-30
FR2365565A1 (en) 1978-04-21
DE2741202C2 (en) 1987-09-10
IL52961A0 (en) 1977-11-30
NL7710382A (en) 1978-03-29
NL186219B (en) 1990-05-16

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Legal Events

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