IE45690L - High density sodium cromoglycate - Google Patents
High density sodium cromoglycateInfo
- Publication number
- IE45690L IE45690L IE771927A IE192777A IE45690L IE 45690 L IE45690 L IE 45690L IE 771927 A IE771927 A IE 771927A IE 192777 A IE192777 A IE 192777A IE 45690 L IE45690 L IE 45690L
- Authority
- IE
- Ireland
- Prior art keywords
- pref
- esp
- degrees
- water
- drying
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/24—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
Abstract
Disodium cromoglycate (I) of apparent density >0.45g/ml (by BS No. 1460 (1967)) is new. Apparent density is pref. 0.5-0.7, esp. 0.53-0.66 g/ml and (I) is pref. in the form of hard granules. Pref. (I) contains 5, esp. 1 wt. % (partic. 0%) other cpds., except for water. Pref. 20 wt. % particles are of dia. >250 mu and is not >60 wt. % are 60 mu (esp. pref. are 20 wt. % at >200 mu and is not >60 wt. % at 90 mu), and 20% are 60 mu (45 mu). Granular (I) may be prepd. by passing (I) of water content 15-35 (esp. 22-24) wt. % through a sieve (4-30 holes inch), then drying to 5-8 wt. % humidity. Pref. water is added prior to sieving at 2 wt. %/min. (0.5-1.5%), pref. by spraying. Granulation is pref. at 50 degrees C and drying is at 60-100 degrees C esp. 75-85 degrees C. (I) is known for use in treating asthma and gastro-intestinal troubles associated with allergic or immunological reactions. The granular form can be encapsulated, easily without the need for flowing aids (i.e. lactose), lubricants etc. The dosage forms are useful in treating e.g. allergy to milk (at 5-250mg) or hay fever (at 1-10mg).
[FR2365565A1]
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB39619/76A GB1549229A (en) | 1976-09-23 | 1976-09-23 | High density sodium cromoglycate |
GB4305476 | 1976-10-16 |
Publications (2)
Publication Number | Publication Date |
---|---|
IE45690L true IE45690L (en) | 1978-03-23 |
IE45690B1 IE45690B1 (en) | 1982-10-20 |
Family
ID=26264184
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IE1927/77A IE45690B1 (en) | 1976-09-23 | 1977-09-21 | High density sodium cromoglycate |
Country Status (8)
Country | Link |
---|---|
JP (1) | JPS5340776A (en) |
AU (1) | AU508134B2 (en) |
DE (1) | DE2741202A1 (en) |
FR (1) | FR2365565A1 (en) |
IE (1) | IE45690B1 (en) |
IL (1) | IL52961A (en) |
NL (1) | NL186219C (en) |
NZ (1) | NZ185240A (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5657540A (en) * | 1979-10-15 | 1981-05-20 | Sanyo Denki Seisakusho:Kk | Fare annunciator for bus provided with controlling function |
JPS634660Y2 (en) * | 1986-10-02 | 1988-02-06 | ||
JPH09152290A (en) * | 1995-11-29 | 1997-06-10 | Sanyo Electric Co Ltd | Absorption refrigerating machine |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2535258C2 (en) * | 1974-08-10 | 1993-06-03 | Fisons Plc, Ipswich, Suffolk | Inhalable drug in pellet form |
GB1520247A (en) * | 1974-08-10 | 1978-08-02 | Fisons Ltd | Pelletised medicament formulations |
-
1977
- 1977-09-13 DE DE19772741202 patent/DE2741202A1/en active Granted
- 1977-09-20 IL IL52961A patent/IL52961A/en unknown
- 1977-09-20 FR FR7728250A patent/FR2365565A1/en active Granted
- 1977-09-21 IE IE1927/77A patent/IE45690B1/en not_active IP Right Cessation
- 1977-09-21 AU AU28983/77A patent/AU508134B2/en not_active Expired
- 1977-09-22 JP JP11343377A patent/JPS5340776A/en active Granted
- 1977-09-22 NL NLAANVRAGE7710382,A patent/NL186219C/en not_active IP Right Cessation
- 1977-09-27 NZ NZ185240A patent/NZ185240A/en unknown
Also Published As
Publication number | Publication date |
---|---|
NL186219C (en) | 1990-10-16 |
DE2741202A1 (en) | 1978-03-30 |
FR2365565A1 (en) | 1978-04-21 |
NL7710382A (en) | 1978-03-29 |
AU508134B2 (en) | 1980-03-13 |
AU2898377A (en) | 1979-03-29 |
IL52961A (en) | 1981-02-27 |
DE2741202C2 (en) | 1987-09-10 |
JPS5340776A (en) | 1978-04-13 |
NL186219B (en) | 1990-05-16 |
JPH0137369B2 (en) | 1989-08-07 |
IE45690B1 (en) | 1982-10-20 |
NZ185240A (en) | 1979-08-31 |
IL52961A0 (en) | 1977-11-30 |
FR2365565B1 (en) | 1980-06-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MK9A | Patent expired |