SE7700665L - PROCEDURE FOR PREPARING A PHARMACEUTICAL COMPOSITION - Google Patents

PROCEDURE FOR PREPARING A PHARMACEUTICAL COMPOSITION

Info

Publication number
SE7700665L
SE7700665L SE7700665A SE7700665A SE7700665L SE 7700665 L SE7700665 L SE 7700665L SE 7700665 A SE7700665 A SE 7700665A SE 7700665 A SE7700665 A SE 7700665A SE 7700665 L SE7700665 L SE 7700665L
Authority
SE
Sweden
Prior art keywords
hereinafter defined
pellet
preparing
procedure
pharmaceutical composition
Prior art date
Application number
SE7700665A
Other languages
Swedish (sv)
Other versions
SE442950B (en
Inventor
J H Bell
Original Assignee
Fisons Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB260676A external-priority patent/GB1569611A/en
Application filed by Fisons Ltd filed Critical Fisons Ltd
Publication of SE7700665L publication Critical patent/SE7700665L/en
Publication of SE442950B publication Critical patent/SE442950B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/24—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

BA 2606/76 MEDICAMENT COMPOSITION IN SOFT PELLET OR GRANULE FORM There is described a medicament in pellet or granule form, wherein the pellet or granule is soft, is from 10 to 1,000, preferably 30 to 500, microns in diameter and comprises an agglomeration of individual medicament particles, at least 90% and preferably at least 95% by weight of which have a diameter of less than 10 microns, characterised in that the pellets or granules have (i) a 'Total Transmitted Load Reduction' (as hereinafter defined) of greater than 100 gms, or (ii) a product of 'Total Transmitted Load Reduction' (as hereinafter defined) and 'Response Lag' (as hereinafter defined) of greater than 30 g/cms, or (iii) a 'Response Lag' (as hereinafter defined) of at least 0.3 cms. The pellets and granules are particularly suitable for inhalation, e.g. in the treatment of asthma or hay fever.
SE7700665A 1976-01-23 1977-01-21 PROCEDURE FOR THE PREPARATION OF A MEDICINAL PRODUCT IN THE FORM OF SOFT PELLET CELLS OR GRANULES SE442950B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB260876 1976-01-23
GB260676A GB1569611A (en) 1976-01-23 1976-01-23 Pelletised or granular medicament formulation

Publications (2)

Publication Number Publication Date
SE7700665L true SE7700665L (en) 1977-07-24
SE442950B SE442950B (en) 1986-02-10

Family

ID=26237614

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7700665A SE442950B (en) 1976-01-23 1977-01-21 PROCEDURE FOR THE PREPARATION OF A MEDICINAL PRODUCT IN THE FORM OF SOFT PELLET CELLS OR GRANULES

Country Status (12)

Country Link
JP (1) JPS5294413A (en)
AU (1) AU506878B2 (en)
CA (1) CA1116516A (en)
DK (1) DK27177A (en)
ES (1) ES455273A1 (en)
FI (1) FI67663C (en)
FR (1) FR2361104A2 (en)
IE (1) IE45260B1 (en)
LU (1) LU76618A1 (en)
NO (1) NO148542C (en)
SE (1) SE442950B (en)
ZA (1) ZA77327B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3268533D1 (en) * 1981-07-24 1986-02-27 Fisons Plc Inhalation drugs, methods for their production and pharmaceutical formulations containing them
US6102036A (en) * 1994-04-12 2000-08-15 Smoke-Stop Breath activated inhaler

Also Published As

Publication number Publication date
DK27177A (en) 1977-07-24
ES455273A1 (en) 1978-04-01
JPS5294413A (en) 1977-08-09
FI67663B (en) 1985-01-31
AU2158977A (en) 1978-08-03
IE45260L (en) 1977-07-23
FR2361104B2 (en) 1982-09-17
LU76618A1 (en) 1977-08-12
CA1116516A (en) 1982-01-19
NO770198L (en) 1977-07-26
FI67663C (en) 1985-05-10
IE45260B1 (en) 1982-07-28
FR2361104A2 (en) 1978-03-10
NO148542B (en) 1983-07-25
NO148542C (en) 1983-11-02
FI770070A (en) 1977-07-24
SE442950B (en) 1986-02-10
AU506878B2 (en) 1980-01-24
ZA77327B (en) 1977-12-28
JPS6228124B2 (en) 1987-06-18

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