DE2701407A1 - Verfahren zur herstellung halbsynthetischer penicillinantibiotika - Google Patents

Verfahren zur herstellung halbsynthetischer penicillinantibiotika

Info

Publication number
DE2701407A1
DE2701407A1 DE19772701407 DE2701407A DE2701407A1 DE 2701407 A1 DE2701407 A1 DE 2701407A1 DE 19772701407 DE19772701407 DE 19772701407 DE 2701407 A DE2701407 A DE 2701407A DE 2701407 A1 DE2701407 A1 DE 2701407A1
Authority
DE
Germany
Prior art keywords
compound
apa
formula
chloride
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19772701407
Other languages
German (de)
English (en)
Inventor
Gino Cotti
Marco Croci
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Laboratories Ltd
Original Assignee
Glaxo Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Laboratories Ltd filed Critical Glaxo Laboratories Ltd
Publication of DE2701407A1 publication Critical patent/DE2701407A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
DE19772701407 1976-01-15 1977-01-14 Verfahren zur herstellung halbsynthetischer penicillinantibiotika Withdrawn DE2701407A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT47642/76A IT1053312B (it) 1976-01-15 1976-01-15 Procedimento per la produzione di antibiotici di penicillina semisintetici

Publications (1)

Publication Number Publication Date
DE2701407A1 true DE2701407A1 (de) 1977-07-21

Family

ID=11261615

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19772701407 Withdrawn DE2701407A1 (de) 1976-01-15 1977-01-14 Verfahren zur herstellung halbsynthetischer penicillinantibiotika

Country Status (14)

Country Link
JP (1) JPS5287190A (enExample)
AU (1) AU512149B2 (enExample)
BE (1) BE850381A (enExample)
CH (1) CH628635A5 (enExample)
DE (1) DE2701407A1 (enExample)
DK (1) DK143705C (enExample)
ES (1) ES455025A1 (enExample)
FR (1) FR2338278A1 (enExample)
GB (1) GB1569426A (enExample)
IT (1) IT1053312B (enExample)
NL (1) NL7700395A (enExample)
SE (1) SE7700392L (enExample)
YU (1) YU9177A (enExample)
ZA (1) ZA77194B (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0953569A1 (en) * 1998-04-29 1999-11-03 Gist-Brocades B.V. Preparation of beta-lactam antibiotics in the presence of urea or amide

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1205103B (de) * 1962-10-17 1965-11-18 Beecham Group Ltd Verfahren zur Herstellung eines 3-Dichlorphenyl-5-methylisoxazolyl-(4)-penicillins
AT251760B (de) * 1962-03-13 1967-01-25 Beecham Group Ltd Verfahren zur Herstellung von Penicillinen
DE1545897A1 (de) * 1964-05-28 1969-12-11 Glaxo Lab Ltd Verfahren zur Acylierung von Verbindungen der Cephalosporinreihe
DE1670641A1 (de) * 1966-11-23 1970-08-06 Lilly Co Eli Verfahren zur Herstellung von Cephalosporinantibiotica

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2220531A1 (en) * 1973-03-06 1974-10-04 Aries Robert Synthesis of penicillins from 6-amino penicillanic acid - by acylation with acid chlorides using hexamethylphosphotriamide as solvent
GB1472746A (en) * 1973-07-05 1977-05-04 Glaxo Lab Ltd Cephalosporin compounds
GB1459807A (en) * 1975-05-27 1976-12-31 Proter Spa Process for the production of 7-d-a-amino-phenyl-acetamido-3- desacetoxy-cephalosporanic acid

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT251760B (de) * 1962-03-13 1967-01-25 Beecham Group Ltd Verfahren zur Herstellung von Penicillinen
DE1205103B (de) * 1962-10-17 1965-11-18 Beecham Group Ltd Verfahren zur Herstellung eines 3-Dichlorphenyl-5-methylisoxazolyl-(4)-penicillins
DE1545897A1 (de) * 1964-05-28 1969-12-11 Glaxo Lab Ltd Verfahren zur Acylierung von Verbindungen der Cephalosporinreihe
DE1670641A1 (de) * 1966-11-23 1970-08-06 Lilly Co Eli Verfahren zur Herstellung von Cephalosporinantibiotica

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
BEILSTEIN: 4. Ergänzungswerk, Bd. 2, Teil 1, 1975, S.404 *
J. Med. Chem., 12, 1969, 703-705 *

Also Published As

Publication number Publication date
IT1053312B (it) 1981-08-31
JPS6135995B2 (enExample) 1986-08-15
DK13877A (da) 1977-07-16
SE7700392L (sv) 1977-07-16
CH628635A5 (en) 1982-03-15
ZA77194B (en) 1977-11-30
JPS5287190A (en) 1977-07-20
AU2133977A (en) 1978-07-20
AU512149B2 (en) 1980-09-25
NL7700395A (nl) 1977-07-19
BE850381A (fr) 1977-07-14
DK143705B (da) 1981-09-28
ES455025A1 (es) 1977-12-16
GB1569426A (en) 1980-06-18
YU9177A (en) 1982-06-30
DK143705C (da) 1982-03-08
FR2338278B1 (enExample) 1981-06-12
FR2338278A1 (fr) 1977-08-12

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
8139 Disposal/non-payment of the annual fee