DE2652677C2 - Antibiotica 890A↓1↓ und 890A↓3↓, Verfahren zu ihrer Herstellung und diese Antibiotika enthaltende antibakterielle Mittel - Google Patents

Antibiotica 890A↓1↓ und 890A↓3↓, Verfahren zu ihrer Herstellung und diese Antibiotika enthaltende antibakterielle Mittel

Info

Publication number
DE2652677C2
DE2652677C2 DE2652677A DE2652677A DE2652677C2 DE 2652677 C2 DE2652677 C2 DE 2652677C2 DE 2652677 A DE2652677 A DE 2652677A DE 2652677 A DE2652677 A DE 2652677A DE 2652677 C2 DE2652677 C2 DE 2652677C2
Authority
DE
Germany
Prior art keywords
antibiotic
fractions
solution
molar
medium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE2652677A
Other languages
German (de)
English (en)
Other versions
DE2652677A1 (de
Inventor
Patrick Joseph Rahway N.J. Cassidy
Robert Thomas Linden N.J. Goegelman
Sebastian Madrid Hernandez
Edward Olley Metuchen N.J. Stapley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of DE2652677A1 publication Critical patent/DE2652677A1/de
Application granted granted Critical
Publication of DE2652677C2 publication Critical patent/DE2652677C2/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/182—Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system
    • C12P17/184—Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system containing a beta-lactam ring, e.g. thienamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE2652677A 1975-11-21 1976-11-19 Antibiotica 890A↓1↓ und 890A↓3↓, Verfahren zu ihrer Herstellung und diese Antibiotika enthaltende antibakterielle Mittel Expired DE2652677C2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US63430075A 1975-11-21 1975-11-21

Publications (2)

Publication Number Publication Date
DE2652677A1 DE2652677A1 (de) 1977-06-02
DE2652677C2 true DE2652677C2 (de) 1985-05-23

Family

ID=24543234

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2652677A Expired DE2652677C2 (de) 1975-11-21 1976-11-19 Antibiotica 890A↓1↓ und 890A↓3↓, Verfahren zu ihrer Herstellung und diese Antibiotika enthaltende antibakterielle Mittel

Country Status (8)

Country Link
JP (1) JPS5265293A (xx)
CH (1) CH625553A5 (xx)
DE (1) DE2652677C2 (xx)
DK (1) DK143712C (xx)
FR (1) FR2332017A1 (xx)
GB (1) GB1561109A (xx)
NL (1) NL7612933A (xx)
SE (1) SE426845B (xx)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK145504C (da) * 1976-04-28 1983-04-25 Merck & Co Inc Fremgangsmaade til fremstilling af det antibiotiske stof 890a2og/eller det antibiotiske stof 890a5 og farmaceutisk acceptable salte deraf
DK488077A (da) * 1976-11-19 1978-05-20 Merck & Co Inc Fremgangsmaade til fremstilling af 3-(2-aminoethylthio)-6(-1-hydroxyethyl)-7-oxo-1-azabicyclo (3.2.0) hept-2-en-2-carboxylsyre
DE2808563A1 (de) * 1977-03-05 1978-09-07 Beecham Group Ltd Derivate der 3-thio-6-(1-hydroxyaethyl)-7-oxo-1-aza-bicyclo eckige klammer auf 3.2.0 eckige klammer zu hept-2-en- 2-carbonsaeure, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US4162323A (en) * 1977-04-18 1979-07-24 Merck & Co., Inc. Antibiotic N-acetyl-dehydro-thienamycin
NZ190994A (en) 1978-07-24 1981-10-19 Merck & Co Inc Z-2-acylamino-3-monosubstituted propenoates

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NICHTS-ERMITTELT

Also Published As

Publication number Publication date
SE7612293L (sv) 1977-05-22
DK143712C (da) 1982-03-22
JPS6253157B2 (xx) 1987-11-09
DK143712B (da) 1981-09-28
JPS5265293A (en) 1977-05-30
DK497176A (da) 1977-05-22
FR2332017B1 (xx) 1980-04-25
NL7612933A (nl) 1977-05-24
SE426845B (sv) 1983-02-14
DE2652677A1 (de) 1977-06-02
CH625553A5 (en) 1981-09-30
FR2332017A1 (fr) 1977-06-17
GB1561109A (en) 1980-02-13

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
8125 Change of the main classification

Ipc: C12P 1/06

D2 Grant after examination
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee