DK488077A - Fremgangsmaade til fremstilling af 3-(2-aminoethylthio)-6(-1-hydroxyethyl)-7-oxo-1-azabicyclo (3.2.0) hept-2-en-2-carboxylsyre - Google Patents

Fremgangsmaade til fremstilling af 3-(2-aminoethylthio)-6(-1-hydroxyethyl)-7-oxo-1-azabicyclo (3.2.0) hept-2-en-2-carboxylsyre

Info

Publication number
DK488077A
DK488077A DK488077A DK488077A DK488077A DK 488077 A DK488077 A DK 488077A DK 488077 A DK488077 A DK 488077A DK 488077 A DK488077 A DK 488077A DK 488077 A DK488077 A DK 488077A
Authority
DK
Denmark
Prior art keywords
aminoethylthio
azabicyclo
hept
oxo
hydroxyethyl
Prior art date
Application number
DK488077A
Other languages
English (en)
Inventor
B G Christensen
D B R Johnston
S M Schmitt
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of DK488077A publication Critical patent/DK488077A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D477/00Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20Sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/39Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by esterified hydroxy groups
    • C07C205/42Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by esterified hydroxy groups having nitro groups or esterified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D477/00Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/26Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK488077A 1976-11-19 1977-11-02 Fremgangsmaade til fremstilling af 3-(2-aminoethylthio)-6(-1-hydroxyethyl)-7-oxo-1-azabicyclo (3.2.0) hept-2-en-2-carboxylsyre DK488077A (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US74336576A 1976-11-19 1976-11-19
US79207177A 1977-04-28 1977-04-28
US83321077A 1977-09-15 1977-09-15

Publications (1)

Publication Number Publication Date
DK488077A true DK488077A (da) 1978-05-20

Family

ID=27419293

Family Applications (1)

Application Number Title Priority Date Filing Date
DK488077A DK488077A (da) 1976-11-19 1977-11-02 Fremgangsmaade til fremstilling af 3-(2-aminoethylthio)-6(-1-hydroxyethyl)-7-oxo-1-azabicyclo (3.2.0) hept-2-en-2-carboxylsyre

Country Status (7)

Country Link
JP (1) JPS5365892A (da)
DE (1) DE2751597A1 (da)
DK (1) DK488077A (da)
FR (1) FR2424921A1 (da)
GB (1) GB1589896A (da)
NL (1) NL7712093A (da)
SE (1) SE436034B (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4061378A (en) * 1977-10-19 1980-04-17 Merck & Co., Inc. 1-azabicyclo (3.2.0) hept-2-enes
AU531084B2 (en) * 1977-10-19 1983-08-11 Merck & Co., Inc. Azetidine derivatives
EP0002564B1 (en) * 1977-11-12 1984-06-20 Beecham Group Plc Derivatives of 7-oxo-1-azabicyclo(3.2.0)-hept-2-ene-2-carboxylic acid, their preparation, pharmaceutical compositions containing them and intermediates
EP0008888B1 (en) * 1978-08-23 1983-09-21 Beecham Group Plc Beta-lactam antibacterial compounds, their preparation and pharmaceutical compositions containing them
EP0017992A1 (en) * 1979-04-19 1980-10-29 Merck & Co. Inc. 2-Substituted-6-substituted-1-carbadethiapen-2-em-3-carboxylic acids, processes for preparing them, antibiotic pharmaceutical compositions containing same and process for preparing intermediates
DE3071008D1 (en) * 1979-04-27 1985-09-26 Merck & Co Inc Process for the preparation of 3-(1-hydroxyethyl)-azetidinones
EP0028151A1 (en) * 1979-10-29 1981-05-06 Beecham Group Plc Process for the preparation of antibiotics
US4309346A (en) * 1980-03-27 1982-01-05 Merck & Co., Inc. Process for the preparation of 1-carbapenems and intermediates via trithioorthoacetates

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK143712C (da) * 1975-11-21 1982-03-22 Merck & Co Inc Fremgangsmaade til fremstilling af de antibiotiske stoffer 890a1 og 890a3

Also Published As

Publication number Publication date
FR2424921B1 (da) 1982-09-10
GB1589896A (en) 1981-05-20
JPS5365892A (en) 1978-06-12
SE436034B (sv) 1984-11-05
SE7712431L (sv) 1978-05-20
JPS6319514B2 (da) 1988-04-22
FR2424921A1 (fr) 1979-11-30
DE2751597A1 (de) 1978-05-24
NL7712093A (nl) 1978-05-23

Similar Documents

Publication Publication Date Title
DK152167C (da) Fremgangsmaade til fremstilling af drageer
DK301077A (da) Fremgangsmade til fremstilling af 6a,10a-transhexahydrodibenzo (b,d) pyran-9-oner
DK147777A (da) Fremgangsmade til fremstilling af acylchromaner
DK148498C (da) Kontinuerlig fremgangsmaade til fremstilling af mikrokapsler.
DK144177A (da) Fremgangsmade til fremstilling af acylayanider
DK153379A (da) Fremgangsmaade til fremstilling af n,n,n!,n!-tetraacetylethylendiamin
DK400381A (da) Fremgansmaade til fremstilling af penicillanoyloxymethyl-penicillanoyloxymethyl-penicillanat-1,1,1!,1!-tetraoxid
DK488077A (da) Fremgangsmaade til fremstilling af 3-(2-aminoethylthio)-6(-1-hydroxyethyl)-7-oxo-1-azabicyclo (3.2.0) hept-2-en-2-carboxylsyre
DK93481A (da) Fremgangsmaade til fremstilling af 7-oxo-1-azabicyclo (3.2.0) hept-2-en-carboxylsyre
DK187577A (da) Fremgangsmade til fremstilling af 1,4-benzodioxsnderivater
DK302777A (da) Fremgangsmade til fremstilling af karameller
DK134978A (da) Fremgangsmaade til fremstilling af 1-azolyl-3,3-dimethyl-1-phenoxy-butan-2-oner
DK80777A (da) Fremgangsmade til fremstilling af 2,3-substituerede, 5,6-kondenserede 4(2h)-aminoalkoxypyranoner
DK185977A (da) Fremgangsmade til fremstilling af 1,3-dihydroheteroarylspiro (isobenzofuraner)
DK301277A (da) Fremgangsmade til fremstilling af substituerede 2,6-methano-2h-1-benzoxociner
DK123578A (da) Fremgangsmaade til fremstilling af 3-(2-aminoethylthio-6-ethyl-7-oxo-1-azabicyclo-(3,2,0)hept-2-en-2-carboxylsyre
NO770863L (no) Fremgangsm}te for opparbeidelse av fortynnede ferrosulfatholdige svovelsyreoppl¦sninger.
DK139029B (da) Analogifremgangsmåde til fremstilling af 5-m-tolyloxyuracil.
DK73077A (da) Fremgangsmade til fremstilling af 2,9-dioxatricyclo (4,3,1,03,7) decaner
DK65877A (da) Fremgangsmaade til fremstilling af mikrokapsler
DK196579A (da) Fremgangsmaade til fremstilling af substituerede dibenzylethere
DK40479A (da) Fremgangsmaade til fremstilling af monorden
NO771707L (no) Fremgangsm}te til h}rfarging.
DK127179A (da) Fremgangsmaade til fremstilling af monokaryoner
DK263577A (da) Fremgangsmade til fremstilling af substituerede 2-v-nyl-chromoner

Legal Events

Date Code Title Description
AHB Application shelved due to non-payment