DE2633492A1 - Derivate von substituierten n-alkylimidazolen und deren herstellung und verwendung - Google Patents

Derivate von substituierten n-alkylimidazolen und deren herstellung und verwendung

Info

Publication number
DE2633492A1
DE2633492A1 DE19762633492 DE2633492A DE2633492A1 DE 2633492 A1 DE2633492 A1 DE 2633492A1 DE 19762633492 DE19762633492 DE 19762633492 DE 2633492 A DE2633492 A DE 2633492A DE 2633492 A1 DE2633492 A1 DE 2633492A1
Authority
DE
Germany
Prior art keywords
imidazole
acid addition
addition salts
chlorophenyl
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
DE19762633492
Other languages
German (de)
English (en)
Other versions
DE2633492C2 (enrdf_load_stackoverflow
Inventor
Keith A M Walker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syntex USA LLC
Original Assignee
Syntex USA LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex USA LLC filed Critical Syntex USA LLC
Publication of DE2633492A1 publication Critical patent/DE2633492A1/de
Application granted granted Critical
Publication of DE2633492C2 publication Critical patent/DE2633492C2/de
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6503—Five-membered rings
    • C07F9/6506—Five-membered rings having the nitrogen atoms in positions 1 and 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DE19762633492 1975-07-28 1976-07-26 Derivate von substituierten n-alkylimidazolen und deren herstellung und verwendung Granted DE2633492A1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US59961875A 1975-07-28 1975-07-28
US66502376A 1976-03-08 1976-03-08

Publications (2)

Publication Number Publication Date
DE2633492A1 true DE2633492A1 (de) 1977-02-24
DE2633492C2 DE2633492C2 (enrdf_load_stackoverflow) 1990-10-25

Family

ID=27083399

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19762633492 Granted DE2633492A1 (de) 1975-07-28 1976-07-26 Derivate von substituierten n-alkylimidazolen und deren herstellung und verwendung

Country Status (14)

Country Link
JP (1) JPS6028820B2 (enrdf_load_stackoverflow)
AU (1) AU505298B2 (enrdf_load_stackoverflow)
CH (2) CH621117A5 (enrdf_load_stackoverflow)
DE (1) DE2633492A1 (enrdf_load_stackoverflow)
ES (2) ES461980A1 (enrdf_load_stackoverflow)
FR (1) FR2319348A1 (enrdf_load_stackoverflow)
GB (1) GB1522717A (enrdf_load_stackoverflow)
HK (1) HK8480A (enrdf_load_stackoverflow)
IE (1) IE43409B1 (enrdf_load_stackoverflow)
MX (1) MX3866E (enrdf_load_stackoverflow)
MY (1) MY8000271A (enrdf_load_stackoverflow)
NL (1) NL183760C (enrdf_load_stackoverflow)
NZ (1) NZ181567A (enrdf_load_stackoverflow)
PH (1) PH14563A (enrdf_load_stackoverflow)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2800755A1 (de) * 1977-01-10 1978-07-13 Syntex Inc 1-eckige klammer auf 2-(halogenphenylthio)-4-(p-chlor- oder -fluorphenyl)-n-butyl eckige klammer zu -imidazole und ihre herstellung
EP0010287A1 (de) * 1978-10-18 1980-04-30 BASF Aktiengesellschaft Gamma-Azolylverbindungen, wachstumsregulierende Mittel, Verfahren zur Herstellung dieser und Verfahren zur Regulierung des Pflanzenwachstums
DE2912288A1 (de) * 1979-03-28 1980-10-09 Bayer Ag Verfahren zur herstellung von hydroxyethyl-azolen
EP0041673A1 (de) * 1980-06-06 1981-12-16 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Imidazolderivate, deren Herstellung sowie diese enthaltende Präparate
EP0105575A1 (en) * 1982-07-12 1984-04-18 G.D. Searle & Co. 1-(1H-imidazolyl), 1-N-morpholinyl and pyridyl compounds, their preparation and pharmaceutical compositions containing them
EP0423524A3 (en) * 1989-09-28 1992-07-08 Maruho Co., Ltd. Propiophenone derivatives and their preparation and pharmaceutical use

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4213991A (en) * 1978-05-30 1980-07-22 Syntex (U.S.A.) Inc. Derivatives of substituted N-alkyl imidazoles and compositions and methods containing the same
DE2963796D1 (en) * 1979-01-22 1982-11-11 Syntex Inc Imidazole derivatives, pharmaceutical compositions containing them and their preparation
JPS55160767A (en) * 1979-05-31 1980-12-13 Idota Yutaka Imidazole derivative
JPS6068220A (ja) * 1983-09-24 1985-04-18 株式会社マキ製作所 フル−ツキヤツプの自動装着方法と装置
JP6229896B2 (ja) * 2013-01-21 2017-11-15 国立大学法人大阪大学 フェノキシアルキルアミン化合物

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1940388A1 (de) * 1968-08-19 1970-02-26 Janssen Pharmaceutica Nv Neue 1-(beta-Aryl)aethylimidazolderivate,ihre Herstellung und Verwendung
DE2063857A1 (de) * 1970-01-13 1971-07-22 Janssen Pharmaceutica, N.V , Beerse (Belgien) Imidazoldenvate
DE2041771A1 (de) * 1970-08-22 1972-02-24 Bayer Ag Neue Phenyl-imidazolyl-alkanyl-Derivate,Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1940388A1 (de) * 1968-08-19 1970-02-26 Janssen Pharmaceutica Nv Neue 1-(beta-Aryl)aethylimidazolderivate,ihre Herstellung und Verwendung
DE2063857A1 (de) * 1970-01-13 1971-07-22 Janssen Pharmaceutica, N.V , Beerse (Belgien) Imidazoldenvate
DE2041771A1 (de) * 1970-08-22 1972-02-24 Bayer Ag Neue Phenyl-imidazolyl-alkanyl-Derivate,Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2800755A1 (de) * 1977-01-10 1978-07-13 Syntex Inc 1-eckige klammer auf 2-(halogenphenylthio)-4-(p-chlor- oder -fluorphenyl)-n-butyl eckige klammer zu -imidazole und ihre herstellung
EP0010287A1 (de) * 1978-10-18 1980-04-30 BASF Aktiengesellschaft Gamma-Azolylverbindungen, wachstumsregulierende Mittel, Verfahren zur Herstellung dieser und Verfahren zur Regulierung des Pflanzenwachstums
DE2912288A1 (de) * 1979-03-28 1980-10-09 Bayer Ag Verfahren zur herstellung von hydroxyethyl-azolen
EP0041673A1 (de) * 1980-06-06 1981-12-16 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Imidazolderivate, deren Herstellung sowie diese enthaltende Präparate
EP0105575A1 (en) * 1982-07-12 1984-04-18 G.D. Searle & Co. 1-(1H-imidazolyl), 1-N-morpholinyl and pyridyl compounds, their preparation and pharmaceutical compositions containing them
EP0423524A3 (en) * 1989-09-28 1992-07-08 Maruho Co., Ltd. Propiophenone derivatives and their preparation and pharmaceutical use

Also Published As

Publication number Publication date
NL7608297A (nl) 1977-02-01
MX3866E (es) 1981-08-26
GB1522717A (en) 1978-08-23
MY8000271A (en) 1980-12-31
AU505298B2 (en) 1979-11-15
HK8480A (en) 1980-03-14
IE43409B1 (en) 1981-02-25
JPS6028820B2 (ja) 1985-07-06
NL183760B (nl) 1988-08-16
AU1622276A (en) 1978-02-02
ES461980A1 (es) 1978-06-01
PH14563A (en) 1981-09-24
NZ181567A (en) 1978-04-28
CH621117A5 (en) 1981-01-15
DE2633492C2 (enrdf_load_stackoverflow) 1990-10-25
JPS5217472A (en) 1977-02-09
IE43409L (en) 1977-01-28
ES461979A1 (es) 1978-12-01
NL183760C (nl) 1989-01-16
FR2319348A1 (fr) 1977-02-25
FR2319348B1 (enrdf_load_stackoverflow) 1979-07-13
CH623040A5 (en) 1981-05-15

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Legal Events

Date Code Title Description
8141 Disposal/no request for examination
8110 Request for examination paragraph 44
D2 Grant after examination
8364 No opposition during term of opposition