DE2623100C2 - Diagnostisches Gerät - Google Patents

Diagnostisches Gerät

Info

Publication number
DE2623100C2
DE2623100C2 DE2623100A DE2623100A DE2623100C2 DE 2623100 C2 DE2623100 C2 DE 2623100C2 DE 2623100 A DE2623100 A DE 2623100A DE 2623100 A DE2623100 A DE 2623100A DE 2623100 C2 DE2623100 C2 DE 2623100C2
Authority
DE
Germany
Prior art keywords
layer
metal
transparent
diagnostic device
substrate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE2623100A
Other languages
German (de)
English (en)
Other versions
DE2623100A1 (de
Inventor
Ivar Schenectady N.Y. Giaever
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
General Electric Co
Original Assignee
General Electric Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by General Electric Co filed Critical General Electric Co
Publication of DE2623100A1 publication Critical patent/DE2623100A1/de
Application granted granted Critical
Publication of DE2623100C2 publication Critical patent/DE2623100C2/de
Expired legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • G01N33/553—Metal or metal coated
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/41—Refractivity; Phase-affecting properties, e.g. optical path length
    • G01N21/45—Refractivity; Phase-affecting properties, e.g. optical path length using interferometric methods; using Schlieren methods
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/26—Web or sheet containing structurally defined element or component, the element or component having a specified physical dimension
    • Y10T428/263—Coating layer not in excess of 5 mils thick or equivalent
    • Y10T428/264—Up to 3 mils
    • Y10T428/265—1 mil or less

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE2623100A 1975-05-27 1976-05-22 Diagnostisches Gerät Expired DE2623100C2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/580,603 US3979184A (en) 1975-05-27 1975-05-27 Diagnostic device for visually detecting presence of biological particles

Publications (2)

Publication Number Publication Date
DE2623100A1 DE2623100A1 (de) 1976-12-09
DE2623100C2 true DE2623100C2 (de) 1985-02-14

Family

ID=24321759

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2623100A Expired DE2623100C2 (de) 1975-05-27 1976-05-22 Diagnostisches Gerät

Country Status (5)

Country Link
US (1) US3979184A (enrdf_load_stackoverflow)
JP (1) JPS51148015A (enrdf_load_stackoverflow)
DE (1) DE2623100C2 (enrdf_load_stackoverflow)
FR (1) FR2312224A1 (enrdf_load_stackoverflow)
GB (1) GB1533286A (enrdf_load_stackoverflow)

Families Citing this family (82)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4054646A (en) * 1973-07-30 1977-10-18 General Electric Method and apparatus for detection of antibodies and antigens
FR2334106A1 (fr) * 1975-12-02 1977-07-01 Pasteur Institut Gel magnetique convenant pour dosages immunoenzymatiques
US4070246A (en) * 1976-04-09 1978-01-24 Abbott Laboratories Reactive matrices
US4090849A (en) * 1976-12-20 1978-05-23 General Electric Company Diagnostic device and manufacture thereof
US4066646A (en) * 1976-12-23 1978-01-03 General Electric Company Diagnostic device and housing therefor
US4108975A (en) * 1977-03-04 1978-08-22 Becton, Dickinson And Company Radioimmunoassay system
US4219335A (en) * 1978-09-18 1980-08-26 E. I. Du Pont De Nemours And Company Immunochemical testing using tagged reagents
US4222743A (en) * 1978-07-20 1980-09-16 Wang Wei Kung Method and apparatus for detecting biological particles by fluorescent stain
US4181501A (en) * 1979-03-26 1980-01-01 General Electric Company Method and apparatus for measuring antibody levels
US4394391A (en) * 1980-02-19 1983-07-19 Thorell Jan Ivan Radioimmunoassay reagents
US4353886A (en) * 1980-05-05 1982-10-12 Irt Corporation Method for detecting organic vapors
US4612281A (en) * 1980-12-03 1986-09-16 Palo Alto Medical Foundation Research Institute Immunoassay for detecting immunoglobulins and test kit
US4442204A (en) * 1981-04-10 1984-04-10 Miles Laboratories, Inc. Homogeneous specific binding assay device and preformed complex method
US4447526A (en) * 1981-04-20 1984-05-08 Miles Laboratories, Inc. Homogeneous specific binding assay with carrier matrix incorporating specific binding partner
DE3176524D1 (en) * 1981-06-22 1987-12-17 Battelle Memorial Institute A method for determining bioactive substances
DE3215484A1 (de) * 1982-04-26 1983-11-03 Sagax Instrument AB, 18302 Täby Aus mehreren schichten bestehender schichtkoerper und verfahren zum nachweis und/oder messen der konzentration einer chemischen substanz, insbesondere biologischer herkunft
AU570425B2 (en) * 1982-12-21 1988-03-17 Applied Research Systems Ars Holding N.V. Assay technique
US5041373A (en) * 1984-01-31 1991-08-20 The Board Of Trustees Of The University Of Illinois Method for determining periodontal disease
IL74191A0 (en) * 1984-01-31 1985-04-30 Univ Illinois Method and kit for determining periodontal disease
US4647544A (en) * 1984-06-25 1987-03-03 Nicoli David F Immunoassay using optical interference detection
US6060237A (en) * 1985-02-26 2000-05-09 Biostar, Inc. Devices and methods for optical detection of nucleic acid hybridization
GB8509492D0 (en) * 1985-04-12 1985-05-15 Plessey Co Plc Optical assay
US5482830A (en) * 1986-02-25 1996-01-09 Biostar, Inc. Devices and methods for detection of an analyte based upon light interference
GB8618133D0 (en) * 1986-07-24 1986-09-03 Pa Consulting Services Biosensors
CA1317206C (en) * 1986-09-22 1993-05-04 Takeyuki Kawaguchi Method for detecting a component of a biological system and detection device and kit therefor
JPS6378051A (ja) * 1986-09-22 1988-04-08 Teijin Ltd 免疫検出用簡易デバイス及び免疫検出方法
GB8705650D0 (en) * 1987-03-10 1987-04-15 Pa Consulting Services Assay technique
JPS6432150A (en) * 1987-07-29 1989-02-02 Teijin Ltd Reflection color measuring instrument
JPH073388B2 (ja) * 1987-08-10 1995-01-18 帝人株式会社 膜厚変化測定装置
DE3808253A1 (de) * 1988-03-12 1989-09-21 Harting Elektronik Gmbh Warenautomat
JP2708590B2 (ja) * 1988-03-28 1998-02-04 スライトル・ウーウェ・ベー 生物学的に活性な分子が固定化された酵素膜，ｅｌｉｓａ膜，センサ膜
GB2217447A (en) * 1988-04-21 1989-10-25 Atomic Energy Authority Uk Bonding to metal surfaces
US5089387A (en) * 1988-07-07 1992-02-18 Adeza Biomedical Corporation Dna probe diffraction assay and reagents
CA1337173C (en) * 1989-04-28 1995-10-03 Westaim Biomedical Corp. Thin film diagnostic device
US5541057A (en) * 1989-09-18 1996-07-30 Biostar, Inc. Methods for detection of an analyte
US5639671A (en) * 1989-09-18 1997-06-17 Biostar, Inc. Methods for optimizing of an optical assay device
US5102883A (en) * 1989-10-31 1992-04-07 Du Pont Merck Pharmaceutical Company Pyrimidine biosynthesis inhibitors useful as immunosuppressive agents
US5008077A (en) * 1989-12-26 1991-04-16 Miles Inc. Easy handling reagent strip
NL9001052A (nl) * 1990-05-02 1991-12-02 Tno Werkwijze voor het bepalen van een specifiek ligand in een vloeibaar monster met behulp van een evanescent veld, alsook een daarvoor geschikt onderdeel van de benodigde meetinrichting.
US5550063A (en) * 1991-02-11 1996-08-27 Biostar, Inc. Methods for production of an optical assay device
US5955377A (en) * 1991-02-11 1999-09-21 Biostar, Inc. Methods and kits for the amplification of thin film based assays
US5837552A (en) * 1991-07-22 1998-11-17 Medifor, Ltd. Surface-enhanced analytical procedures and substrates
US5418136A (en) * 1991-10-01 1995-05-23 Biostar, Inc. Devices for detection of an analyte based upon light interference
EP0727038B1 (en) * 1992-07-31 2005-12-14 Thermo Biostar, Inc. Devices and methods for detection of an analyte based upon light interference
US5494829A (en) * 1992-07-31 1996-02-27 Biostar, Inc. Devices and methods for detection of an analyte based upon light interference
US5552272A (en) * 1993-06-10 1996-09-03 Biostar, Inc. Detection of an analyte by fluorescence using a thin film optical device
US5413939A (en) * 1993-06-29 1995-05-09 First Medical, Inc. Solid-phase binding assay system for interferometrically measuring analytes bound to an active receptor
US6660233B1 (en) * 1996-01-16 2003-12-09 Beckman Coulter, Inc. Analytical biochemistry system with robotically carried bioarray
US5679579A (en) * 1996-01-29 1997-10-21 First Medical, Inc. Immunofluorescence measurement of analytes bound to a substrate and apparatus therefor
US6437563B1 (en) 1997-11-21 2002-08-20 Quantum Design, Inc. Method and apparatus for making measurements of accumulations of magnetically susceptible particles combined with analytes
US7167615B1 (en) 1999-11-05 2007-01-23 Board Of Regents, The University Of Texas System Resonant waveguide-grating filters and sensors and methods for making and using same
FR2818378B1 (fr) * 2000-12-14 2003-06-13 Commissariat Energie Atomique Dispositif de renforcement de fluorescence large bande a faibles pertes et capteur optique biologique ou chimique l'utilisant
US20020168756A1 (en) * 2001-03-23 2002-11-14 Fuji Photo Film Co., Ltd. Particle size variable reactor
US7077982B2 (en) * 2001-03-23 2006-07-18 Fuji Photo Film Co., Ltd. Molecular electric wire, molecular electric wire circuit using the same and process for producing the molecular electric wire circuit
US7018795B2 (en) * 2001-03-23 2006-03-28 Fuji Photo Film Co., Ltd. Hybridization probe and target nucleic acid detecting kit, target nucleic acid detecting apparatus and target nucleic acid detecting method using the same
US20030003476A1 (en) * 2001-03-23 2003-01-02 Fuji Photo Film Co., Ltd. Waste water inspecting agent and waste water inspecting apparatus using the same
US20020168667A1 (en) * 2001-03-23 2002-11-14 Fuji Photo Film Co., Ltd. Antigen detecting agent and antigen detecting kit, antigen detecting apparatus and antigen detecting method using the same
US20020168291A1 (en) * 2001-03-23 2002-11-14 Fuji Photo Film Co., Ltd. Agent for health inspection and health inspection apparatus using the same
US20030108726A1 (en) * 2001-10-18 2003-06-12 Schembri Carol T. Chemical arrays
US20030179381A1 (en) * 2002-03-18 2003-09-25 Fuji Photo Film Co., Ltd. Sensor, color sensor and apparatus for inspection using the same
US7449146B2 (en) * 2002-09-30 2008-11-11 3M Innovative Properties Company Colorimetric sensor
US20040062682A1 (en) * 2002-09-30 2004-04-01 Rakow Neal Anthony Colorimetric sensor
US7390457B2 (en) * 2002-10-31 2008-06-24 Agilent Technologies, Inc. Integrated microfluidic array device
US20040086869A1 (en) * 2002-10-31 2004-05-06 Schembri Carol T. Device having multiple molecular arrays
US20040087009A1 (en) * 2002-10-31 2004-05-06 Schembri Carol T. Array substrates having protective layer
US7364896B2 (en) 2002-10-31 2008-04-29 Agilent Technologies, Inc. Test strips including flexible array substrates and method of hybridization
JP4294946B2 (ja) * 2002-12-13 2009-07-15 富士フイルム株式会社 標的検出装置及び標的検出方法並びに標的検出用基材
US7076127B2 (en) * 2003-01-14 2006-07-11 Fuji Photo Film Co., Ltd. Optical switch and safety apparatus using the same
JP2004279196A (ja) * 2003-03-14 2004-10-07 Dainippon Printing Co Ltd バイオマイクロアレイ用基板およびバイオマイクロアレイ
WO2006135097A1 (en) 2005-06-14 2006-12-21 Fujifilm Corporation Sensor, multichannel sensor, sensing apparatus, and sensing method
US7767143B2 (en) 2006-06-27 2010-08-03 3M Innovative Properties Company Colorimetric sensors
US8697437B1 (en) 2008-08-29 2014-04-15 University Of South Florida Magnetic metabolite and diagnostic transfer disks
US9459212B2 (en) * 2009-12-17 2016-10-04 University Of Maryland, Baltimore County Mixed-metal substrates for metal-enhanced fluorescence
DE102011109338B3 (de) * 2011-08-03 2013-01-31 Dietrich Reichwein Vorrichtung zur Speicherung elektromagnetischer Energie
JP2014169955A (ja) 2013-03-05 2014-09-18 Seiko Epson Corp 分析装置、分析方法、これらに用いる光学素子および電子機器、並びに光学素子の設計方法
JP6365817B2 (ja) 2014-02-17 2018-08-01 セイコーエプソン株式会社 分析装置、及び電子機器
JP2015215178A (ja) 2014-05-08 2015-12-03 セイコーエプソン株式会社 電場増強素子、分析装置及び電子機器
CN107764991B (zh) * 2016-08-22 2019-11-12 苏州偲聚生物材料有限公司 能够提高检测灵敏度的固相载体及检测器件
CN111699255B (zh) * 2018-02-09 2024-03-08 首尔大学校产学协力团 基于生物反应器的生物样品分析方法、分析芯片及分析系统
CN109709073B (zh) * 2019-01-10 2021-10-22 苏州市东挺河智能科技发展有限公司 一种纳米小球膜层数检测装置
CN109632711B (zh) * 2019-01-10 2021-10-01 山东拓步教育科技有限公司 一种ps小球层数检测装置
WO2021119814A1 (en) 2019-12-20 2021-06-24 Sn Biomedical Inc. Optical interference diagnostic apparatus and methods of use

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3271179A (en) * 1962-09-24 1966-09-06 Temescal Metallurgical Corp Method for the manufacture of an optical filter
US3530055A (en) * 1968-08-26 1970-09-22 Ibm Formation of layers of solids on substrates
US3691045A (en) * 1971-03-15 1972-09-12 Corning Glass Works Method of making photochromic films on glass substrates
CA1025772A (en) * 1972-06-26 1978-02-07 Ivar Giaever Method and apparatus for detection and purification of proteins and antibodies
US3853467A (en) * 1973-08-15 1974-12-10 Gen Electric Method and apparatus for immunological detection of biological particles
US3926564A (en) * 1974-02-25 1975-12-16 Gen Electric Substrate for immunological tests and method of fabrication thereof

Also Published As

Publication number Publication date
DE2623100A1 (de) 1976-12-09
JPS51148015A (en) 1976-12-18
FR2312224B1 (enrdf_load_stackoverflow) 1982-10-29
GB1533286A (en) 1978-11-22
FR2312224A1 (fr) 1976-12-24
JPS6137581B2 (enrdf_load_stackoverflow) 1986-08-25
US3979184A (en) 1976-09-07

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