DE2612114A1 - Prostaglandin-derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische oder veterinaermedizinische zusammensetzungen - Google Patents

Prostaglandin-derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische oder veterinaermedizinische zusammensetzungen

Info

Publication number
DE2612114A1
DE2612114A1 DE19762612114 DE2612114A DE2612114A1 DE 2612114 A1 DE2612114 A1 DE 2612114A1 DE 19762612114 DE19762612114 DE 19762612114 DE 2612114 A DE2612114 A DE 2612114A DE 2612114 A1 DE2612114 A1 DE 2612114A1
Authority
DE
Germany
Prior art keywords
pyrrolidinone
hexyl
mixture
octen
isomers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19762612114
Other languages
German (de)
English (en)
Inventor
Pierre Luc Eymard
Alain Jean
Charles Pigerol
Jacques Simiand
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Labaz SA
Original Assignee
Labaz SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Labaz SA filed Critical Labaz SA
Publication of DE2612114A1 publication Critical patent/DE2612114A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/04—Saturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/16—Saturated compounds containing keto groups bound to acyclic carbon atoms containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/377—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups
    • C07C51/38—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups by decarboxylation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/185—Saturated compounds having only one carboxyl group and containing keto groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic Table
    • C07F1/005—Compounds containing elements of Groups 1 or 11 of the Periodic Table without C-Metal linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/54—Quaternary phosphonium compounds
    • C07F9/5407—Acyclic saturated phosphonium compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE19762612114 1975-03-21 1976-03-22 Prostaglandin-derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische oder veterinaermedizinische zusammensetzungen Withdrawn DE2612114A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB12034/75A GB1529852A (en) 1975-03-21 1975-03-21 8-azaprostaglandins and process for the preparation thereof

Publications (1)

Publication Number Publication Date
DE2612114A1 true DE2612114A1 (de) 1976-10-07

Family

ID=9997230

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19762612114 Withdrawn DE2612114A1 (de) 1975-03-21 1976-03-22 Prostaglandin-derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische oder veterinaermedizinische zusammensetzungen

Country Status (26)

Country Link
JP (1) JPS607602B2 (enExample)
AR (1) AR213172A1 (enExample)
AT (1) AT348163B (enExample)
AU (1) AU501105B2 (enExample)
BE (1) BE839761A (enExample)
CA (1) CA1076587A (enExample)
CH (2) CH611604A5 (enExample)
DE (1) DE2612114A1 (enExample)
DK (1) DK140937B (enExample)
ES (2) ES446239A1 (enExample)
FI (1) FI61692C (enExample)
FR (1) FR2304340A1 (enExample)
GB (1) GB1529852A (enExample)
HU (1) HU173348B (enExample)
IE (1) IE42966B1 (enExample)
IT (1) IT1061011B (enExample)
MX (1) MX3301E (enExample)
NL (1) NL7602891A (enExample)
NO (1) NO144147C (enExample)
NZ (1) NZ180251A (enExample)
OA (1) OA05279A (enExample)
PT (1) PT64919B (enExample)
SE (1) SE418290B (enExample)
SU (1) SU614746A3 (enExample)
YU (1) YU73876A (enExample)
ZA (1) ZA761448B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2826096A1 (de) * 1977-06-17 1979-01-04 Upjohn Co Prostaglandinanaloga

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5540618A (en) * 1994-10-28 1996-07-30 National University Of Singapore Passive attenuator for shelter protection against explosions
AU2003211574A1 (en) 2002-03-05 2003-09-16 Ono Pharmaceutical Co., Ltd. 8-azaprostaglandin derivative compounds and drugs containing the compounds as the active ingredient

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2826096A1 (de) * 1977-06-17 1979-01-04 Upjohn Co Prostaglandinanaloga

Also Published As

Publication number Publication date
IT1061011B (it) 1982-10-20
BE839761A (fr) 1976-09-20
FR2304340A1 (fr) 1976-10-15
CA1076587A (en) 1980-04-29
ES458389A1 (es) 1978-02-16
SU614746A3 (ru) 1978-07-05
JPS607602B2 (ja) 1985-02-26
SE418290B (sv) 1981-05-18
AU501105B2 (en) 1979-06-14
AU1189976A (en) 1977-09-15
GB1529852A (en) 1978-10-25
YU73876A (en) 1982-10-31
DK140937B (da) 1979-12-10
AT348163B (de) 1979-02-12
AR213172A1 (es) 1978-12-29
HU173348B (hu) 1979-04-28
PT64919B (en) 1977-08-24
ZA761448B (en) 1977-03-30
NO760994L (enExample) 1976-09-22
OA05279A (fr) 1981-02-28
DK88276A (enExample) 1976-09-22
FI760744A7 (enExample) 1976-09-22
SE7603400L (sv) 1976-09-22
IE42966B1 (en) 1980-11-19
NL7602891A (nl) 1976-09-23
NO144147B (no) 1981-03-23
FI61692C (fi) 1982-09-10
JPS51138671A (en) 1976-11-30
ES446239A1 (es) 1977-07-01
PT64919A (en) 1976-04-01
ATA195676A (de) 1978-06-15
DK140937C (enExample) 1980-05-19
NZ180251A (en) 1978-07-28
FI61692B (fi) 1982-05-31
MX3301E (es) 1980-09-03
NO144147C (no) 1981-07-15
CH611881A5 (en) 1979-06-29
CH611604A5 (en) 1979-06-15
FR2304340B1 (enExample) 1979-06-29
IE42966L (en) 1976-09-21

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Legal Events

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8139 Disposal/non-payment of the annual fee