DE2557870A1 - Verfahren und vorrichtung zum tiefgefrieren von biologischen substanzen - Google Patents

Verfahren und vorrichtung zum tiefgefrieren von biologischen substanzen

Info

Publication number
DE2557870A1
DE2557870A1 DE19752557870 DE2557870A DE2557870A1 DE 2557870 A1 DE2557870 A1 DE 2557870A1 DE 19752557870 DE19752557870 DE 19752557870 DE 2557870 A DE2557870 A DE 2557870A DE 2557870 A1 DE2557870 A1 DE 2557870A1
Authority
DE
Germany
Prior art keywords
cooling medium
container
bio
control unit
containers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19752557870
Other languages
German (de)
English (en)
Inventor
Horst Dr Ing Chmiel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Linde GmbH
Original Assignee
Linde GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Linde GmbH filed Critical Linde GmbH
Priority to DE19752557870 priority Critical patent/DE2557870A1/de
Priority to AT124976A priority patent/AT351679B/de
Priority to JP51152159A priority patent/JPS6048481B2/ja
Priority to GB53220/76A priority patent/GB1519710A/en
Priority to BE6045802A priority patent/BE849649A/xx
Priority to AU20753/76A priority patent/AU503476B2/en
Priority to CH1600976A priority patent/CH624830A5/de
Priority to NL7614151A priority patent/NL7614151A/xx
Priority to DK573976A priority patent/DK573976A/da
Priority to FR7638269A priority patent/FR2338467A1/fr
Priority to CA268,399A priority patent/CA1058522A/en
Priority to US05/752,930 priority patent/US4107937A/en
Publication of DE2557870A1 publication Critical patent/DE2557870A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
    • F25D29/00—Arrangement or mounting of control or safety devices
    • F25D29/001—Arrangement or mounting of control or safety devices for cryogenic fluid systems

Landscapes

  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Combustion & Propulsion (AREA)
  • Physics & Mathematics (AREA)
  • Mechanical Engineering (AREA)
  • Thermal Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
DE19752557870 1975-12-22 1975-12-22 Verfahren und vorrichtung zum tiefgefrieren von biologischen substanzen Withdrawn DE2557870A1 (de)

Priority Applications (12)

Application Number Priority Date Filing Date Title
DE19752557870 DE2557870A1 (de) 1975-12-22 1975-12-22 Verfahren und vorrichtung zum tiefgefrieren von biologischen substanzen
AT124976A AT351679B (de) 1975-12-22 1976-02-23 Verfahren und vorrichtung zum tiefgefrieren von biologischen substanzen
JP51152159A JPS6048481B2 (ja) 1975-12-22 1976-12-20 生体物質の低温冷凍方法及び装置
GB53220/76A GB1519710A (en) 1975-12-22 1976-12-20 Deep-freezing of biological materials
BE6045802A BE849649A (fr) 1975-12-22 1976-12-20 Procede et dispositif de congelation profonde de substances biologiques
AU20753/76A AU503476B2 (en) 1975-12-22 1976-12-20 Procedure and device for deep-freezing biological specimens
CH1600976A CH624830A5 (enExample) 1975-12-22 1976-12-20
NL7614151A NL7614151A (nl) 1975-12-22 1976-12-20 Werkwijze en inrichting voor het diep invriezen van biologische stoffen.
DK573976A DK573976A (da) 1975-12-22 1976-12-20 Fremgangsmade og apparat til dybfrysning af biologiske stoffer
FR7638269A FR2338467A1 (fr) 1975-12-22 1976-12-20 Procede et dispositif de congelation profonde de substances biologiques
CA268,399A CA1058522A (en) 1975-12-22 1976-12-21 Method of and apparatus for the deep freezing of biological substances
US05/752,930 US4107937A (en) 1975-12-22 1976-12-21 Method of and apparatus for the deep freezing of biological substances

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19752557870 DE2557870A1 (de) 1975-12-22 1975-12-22 Verfahren und vorrichtung zum tiefgefrieren von biologischen substanzen

Publications (1)

Publication Number Publication Date
DE2557870A1 true DE2557870A1 (de) 1977-06-23

Family

ID=5965207

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19752557870 Withdrawn DE2557870A1 (de) 1975-12-22 1975-12-22 Verfahren und vorrichtung zum tiefgefrieren von biologischen substanzen

Country Status (12)

Country Link
US (1) US4107937A (enExample)
JP (1) JPS6048481B2 (enExample)
AT (1) AT351679B (enExample)
AU (1) AU503476B2 (enExample)
BE (1) BE849649A (enExample)
CA (1) CA1058522A (enExample)
CH (1) CH624830A5 (enExample)
DE (1) DE2557870A1 (enExample)
DK (1) DK573976A (enExample)
FR (1) FR2338467A1 (enExample)
GB (1) GB1519710A (enExample)
NL (1) NL7614151A (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006033098A1 (de) * 2006-07-14 2008-01-24 Rebholz, Erich, Dr. Verfahren und Einrichtung zum Zwischenlagern von Mikroben

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US4771392A (en) * 1978-01-30 1988-09-13 Edmund F. Bard Programmable time varying control system and method
US4327799A (en) * 1979-06-18 1982-05-04 Helmholtz-Institut Fur Biomedizinische Technik Process and apparatus for freezing living cells
US4304293A (en) * 1979-06-18 1981-12-08 Helmholtz-Institut Fur Biomedizinische Technik Process and apparatus for freezing living cells
FR2460460A1 (fr) * 1979-06-28 1981-01-23 Rivoire Jacques Dispositif cryogenique stable et precis
US4336691A (en) * 1979-12-13 1982-06-29 The Board Of Trustees Of The Leland Stanford Junior University Cryojet rapid freezing apparatus
DE3015672A1 (de) * 1980-04-23 1981-10-29 Drabert Söhne Minden (Westf.), 4950 Minden Verfahren und vorrichtung zum verbessern der qualitaet von bahnfoermigen materialien
US4346754A (en) * 1980-04-30 1982-08-31 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Heating and cooling system
US4407136A (en) * 1982-03-29 1983-10-04 Halliburton Company Downhole tool cooling system
JPS6056B2 (ja) * 1983-01-14 1985-01-05 株式会社 ほくさん 受精卵、精子等の凍結装置
AU584312B2 (en) * 1984-01-17 1989-05-25 Hoxan Corporation Method of fabricating frozen fine liver pieces for artificial liver, apparatus for freezing the same, and freezing vessel
US4531373A (en) * 1984-10-24 1985-07-30 The Regents Of The University Of California Directional solidification for the controlled freezing of biomaterials
GB2168798B (en) * 1984-12-19 1989-05-17 Charles Raymond Micallef A method and apparatus for cooling beverage in a bottle
DE3639760A1 (de) * 1985-11-28 1987-06-04 Mitsubishi Electric Corp Kuehlmittelbehaelter
USRE33567E (en) * 1986-02-25 1991-04-09 Micromeritics Instrument Corporation Temperature controlling apparatus for use with pore volume and surface area analyzers
DE3610563A1 (de) * 1986-03-27 1987-10-01 Messer Griesheim Gmbh Vorrichtung zum gefrieren von auf einem hordewagen befindlichen lebensmitteln
US4963489A (en) * 1987-04-14 1990-10-16 Marrow-Tech, Inc. Three-dimensional cell and tissue culture system
US5160490A (en) * 1986-04-18 1992-11-03 Marrow-Tech Incorporated Three-dimensional cell and tissue culture apparatus
US4721096A (en) * 1986-04-18 1988-01-26 Marrow-Tech Incorporated Process for replicating bone marrow in vitro and using the same
US5266480A (en) * 1986-04-18 1993-11-30 Advanced Tissue Sciences, Inc. Three-dimensional skin culture system
US5032508A (en) * 1988-09-08 1991-07-16 Marrow-Tech, Inc. Three-dimensional cell and tissue culture system
US5863531A (en) * 1986-04-18 1999-01-26 Advanced Tissue Sciences, Inc. In vitro preparation of tubular tissue structures by stromal cell culture on a three-dimensional framework
US5510254A (en) * 1986-04-18 1996-04-23 Advanced Tissue Sciences, Inc. Three dimensional cell and tissue culture system
DE3619788A1 (de) * 1986-06-12 1987-12-17 Messer Griesheim Gmbh Vorrichtung zum abkuehlen von gummierten grossbehaeltern mit fluessigem stickstoff
US4967382A (en) * 1987-01-09 1990-10-30 Hall Burness C Programmable time varying control system and method
US4790141A (en) * 1987-12-14 1988-12-13 Industrial Gas And Supply Company Apparatus and process for quick freezing of blood plasma
DE8717091U1 (de) * 1987-12-30 1988-03-10 Colora Messtechnik Gmbh, 7073 Lorch Gerät zum Schockgefrieren von Blutplasma
JPH07122619B2 (ja) * 1988-10-13 1995-12-25 セイコー電子工業株式会社 分析装置
US5087617A (en) * 1989-02-15 1992-02-11 Board Of Regents, The University Of Texas System Methods and compositions for treatment of cancer using oligonucleotides
US5248671A (en) * 1989-02-15 1993-09-28 Board Of Regents, The University Of Texas System Methods and compositions for treatment of cancer using oligonucleotides
US4934151A (en) * 1989-07-07 1990-06-19 Kyokujitsu Company., Ltd. Continuous multistage thermal processing apparatus, freezing control method for use by the apparatus, and apparatus for preparing a recording medium for the control method
US5003787A (en) * 1990-01-18 1991-04-02 Savant Instruments Cell preservation system
US5100676A (en) * 1990-02-02 1992-03-31 Biosurface Technology, Inc. Cool storage of cultured epithelial sheets
ATE161408T1 (de) * 1990-04-24 1998-01-15 Mark Eisenberg Zusammengesetztes äquivalent der lebenden haut
US5328821A (en) * 1991-12-12 1994-07-12 Robyn Fisher Cold and cryo-preservation methods for human tissue slices
US5533343A (en) * 1994-07-07 1996-07-09 Tyson Holding Company Freezing system
DE4437091C2 (de) * 1994-10-17 2003-07-03 Andreas Sputtek Friercontainer
US5689961A (en) * 1996-01-30 1997-11-25 Organogenesis Inc. Ice seeding apparatus for cryopreservation systems
US5827729A (en) * 1996-04-23 1998-10-27 Advanced Tissue Sciences Diffusion gradient bioreactor and extracorporeal liver device using a three-dimensional liver tissue
DE59805560D1 (de) * 1997-01-13 2002-10-24 Daniel Studer Probenhalter für wasserhaltige Proben sowie Verfahren zu deren Verwendung
US6293048B1 (en) * 1999-06-07 2001-09-25 Clay Boulter Hydroponic feeder and cooler
DE10015773A1 (de) * 2000-03-30 2001-10-04 Leica Mikrosysteme Gmbh Wien Probenhalter für wasserhaltige Präparate und Verfahren zu dessen Verwendung sowie Hochdruckgefriereinrichtung für den Probenhalter
US6631616B2 (en) 2001-05-22 2003-10-14 Richard Wisniewski Cryopreservation system with controlled dendritic freezing front velocity
US6945056B2 (en) * 2001-11-01 2005-09-20 Integrated Biosystems, Inc. Systems and methods for freezing, mixing and thawing biopharmaceutical material
US6684646B2 (en) 2001-05-22 2004-02-03 Integrated Biosystems, Inc. Systems and methods for freezing, storing and thawing biopharmaceutical material
US6635414B2 (en) 2001-05-22 2003-10-21 Integrated Biosystems, Inc. Cryopreservation system with controlled dendritic freezing front velocity
US6698213B2 (en) * 2001-05-22 2004-03-02 Integrated Biosystems, Inc. Systems and methods for freezing and storing biopharmaceutical material
EP1665931A3 (en) * 2001-11-01 2006-06-14 Integrated Biosystems, Inc. System and methods for freezing and storing biopharmaceutical material
DK1441586T3 (da) * 2001-11-01 2006-10-23 Integrated Biosystems Inc Apparat og fremgangsmåde til frysning og lagring af biofarmaceutisk materiale
US7104074B2 (en) 2001-11-01 2006-09-12 Integrated Biosystems, Inc. Systems and methods for freezing, storing, transporting and thawing biopharmaceutical material
DE10346793B4 (de) * 2003-10-08 2007-04-19 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Kühleinrichtung zur Kryokonservierung und entsprechendes Betriebsverfahren
IL158599A0 (en) * 2003-10-26 2004-05-12 Yeda Res & Dev Methods of modulating hematopoiesis
CA2547292A1 (en) * 2003-11-28 2005-06-09 Snow Factories Sa Snow making method and apparatus
US8028532B2 (en) * 2006-03-06 2011-10-04 Sartorius Stedim North America Inc. Systems and methods for freezing, storing and thawing biopharmaceutical materials
US20090094995A1 (en) * 2006-06-15 2009-04-16 Air Liquide Industrial U.S. Lp System and method for processing food products with fluid recirculation and chilling
EP2063706A2 (en) * 2006-09-11 2009-06-03 I.M.T. Interface Multigrad Technology Ltd. Systems, devices and methods for freezing and thawing biological materials
ES2400410T3 (es) * 2007-11-09 2013-04-09 Praxair Technology, Inc. Método y sistema para la congelación a velocidad controlada de material biológico
CN101939631A (zh) * 2008-01-17 2011-01-05 库克泌尿科学公司万斯产品公司 用于玻璃化的快速冷却设备
WO2012138944A1 (en) * 2011-04-06 2012-10-11 Celltronix Method and scalable devices for hyper-fast cooling
EP2710347B1 (en) 2011-05-18 2020-08-26 Biocision, LLC Ventilation assisted passive cell freezing device
US10098685B2 (en) 2013-10-30 2018-10-16 Medtronic Cryocath Lp Feedback system for cryoablation of cardiac tissue
FR3023714A1 (fr) * 2014-07-18 2016-01-22 Lab Francais Du Fractionnement Emballage de medicament de therapie innovante
EP4067860B1 (en) 2021-03-31 2024-07-24 FEI Company Method of preparing a cryogenic sample with improved cooling characteristics
CN113142193B (zh) * 2021-05-27 2024-01-30 上海理工大学 一种细胞程序冷冻方法、系统、设备、介质及装置
CN113803924B (zh) * 2021-09-17 2023-08-18 山东中科赛奥生物科技有限公司 一种防止细胞污染的细胞冷藏箱
WO2023178029A1 (en) * 2022-03-14 2023-09-21 Tff Pharmaceuticals, Inc. Large scale synthesis of pharmaceutical and biologic formulations using thin film freezing

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US3347745A (en) * 1963-12-06 1967-10-17 Union Carbide Corp Process for freezing erythrocytes
US3758382A (en) * 1968-07-26 1973-09-11 Us Navy Ve agent process of freezing blood using a hydroxyalkyl starch as cryoprotecti

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GB668450A (en) * 1949-11-24 1952-03-19 Ateliers Et Chantiers Loire Sa Method and device for the congelation of liquids
US2662520A (en) * 1951-02-06 1953-12-15 Little Inc A Preservation and storage of biological materials
DE1186207B (de) * 1958-06-04 1965-01-28 Krauss Maffei Ag Heiz- und Kuehlvorrichtung fuer thermoplastische Kunststoffe verarbeitende Schneckenpressen
FR1278211A (fr) * 1960-11-08 1961-12-08 Union Carbide Corp Conservation de substances biologiques, en particulier du sang
US3753357A (en) * 1970-12-14 1973-08-21 Ovitron Res Corp Method and apparatus for the preservation of cells and tissues
GB1418400A (en) * 1973-03-14 1975-12-17 Nippon Kokan Kk Method and apparatus for cooling steel
US3940943A (en) * 1975-01-22 1976-03-02 The Curators Of The University Of Missouri Multistage freezing system for preservation of biological materials

Patent Citations (2)

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US3347745A (en) * 1963-12-06 1967-10-17 Union Carbide Corp Process for freezing erythrocytes
US3758382A (en) * 1968-07-26 1973-09-11 Us Navy Ve agent process of freezing blood using a hydroxyalkyl starch as cryoprotecti

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Title
Chemie-Ing.-Technik 47, Nr.8, (1975), S.345 *
PATAT F. u. KIRCHNER K.: Praktikum der technischenChemie W. de Gruyter, Berlin, 1963, S.207-210 *
VDI-Bericht Nr.232 (1975), S.42-50 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006033098A1 (de) * 2006-07-14 2008-01-24 Rebholz, Erich, Dr. Verfahren und Einrichtung zum Zwischenlagern von Mikroben

Also Published As

Publication number Publication date
GB1519710A (en) 1978-08-02
FR2338467A1 (fr) 1977-08-12
US4107937A (en) 1978-08-22
BE849649A (fr) 1977-06-20
NL7614151A (nl) 1977-06-24
JPS5290619A (en) 1977-07-30
JPS6048481B2 (ja) 1985-10-28
AT351679B (de) 1979-08-10
AU2075376A (en) 1978-06-29
ATA124976A (de) 1979-01-15
CH624830A5 (enExample) 1981-08-31
AU503476B2 (en) 1979-09-06
FR2338467B1 (enExample) 1980-06-27
DK573976A (da) 1977-06-23
CA1058522A (en) 1979-07-17

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OD Request for examination
8139 Disposal/non-payment of the annual fee