DE2555408C2 - - Google Patents

Info

Publication number
DE2555408C2
DE2555408C2 DE2555408A DE2555408A DE2555408C2 DE 2555408 C2 DE2555408 C2 DE 2555408C2 DE 2555408 A DE2555408 A DE 2555408A DE 2555408 A DE2555408 A DE 2555408A DE 2555408 C2 DE2555408 C2 DE 2555408C2
Authority
DE
Germany
Prior art keywords
perfluorinated
emulsion
blood
volume
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE2555408A
Other languages
German (de)
English (en)
Other versions
DE2555408A1 (de
Inventor
Robert Emory Wilmington Del. Us Moore
Leland Charles Ph.D. Cincinnati Ohio Us Clark Jun.
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cincinnati Childrens Hospital Medical Center
Original Assignee
Cincinnati Childrens Hospital Medical Center
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cincinnati Childrens Hospital Medical Center filed Critical Cincinnati Childrens Hospital Medical Center
Publication of DE2555408A1 publication Critical patent/DE2555408A1/de
Application granted granted Critical
Publication of DE2555408C2 publication Critical patent/DE2555408C2/de
Granted legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0026Blood substitute; Oxygen transporting formulations; Plasma extender
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/02Halogenated hydrocarbons
    • A61K31/025Halogenated hydrocarbons carbocyclic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DE19752555408 1974-12-09 1975-12-09 Emulsion einer perfluorierten verbindung in wasser Granted DE2555408A1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US53079174A 1974-12-09 1974-12-09
US57976675A 1975-05-22 1975-05-22

Publications (2)

Publication Number Publication Date
DE2555408A1 DE2555408A1 (de) 1976-06-10
DE2555408C2 true DE2555408C2 (es) 1988-06-23

Family

ID=27063372

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19752555408 Granted DE2555408A1 (de) 1974-12-09 1975-12-09 Emulsion einer perfluorierten verbindung in wasser

Country Status (12)

Country Link
JP (1) JPS5753762B2 (es)
CA (1) CA1058081A (es)
CH (1) CH629938A5 (es)
DE (1) DE2555408A1 (es)
DK (1) DK154605C (es)
FI (1) FI54560C (es)
FR (1) FR2313024A1 (es)
GB (1) GB1531418A (es)
IT (1) IT1050731B (es)
NL (1) NL184995C (es)
NO (1) NO754103L (es)
SE (2) SE7513814L (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2515198A1 (fr) * 1981-10-22 1983-04-29 Centre Nat Rech Scient Microemulsions aqueuses de fluorocarbures indefiniment stables a une temperature donnee, procede d'obtention et application a titre de transporteurs d'oxygene
US4569784A (en) * 1980-11-17 1986-02-11 Adamantech, Inc. Preparation of a gel having gas transporting capability
GB8504916D0 (en) * 1985-02-26 1985-03-27 Isc Chemicals Ltd Emulsions of perfluorocarbons in aqueous media
DE4100059C2 (de) * 1991-01-03 1994-08-25 Adatomed Pharma & Med Behandlungsflüssigkeit zum Wiederanlegen (Entfalten) abgelöster Netzhaut an die Aderhaut des Auges
WO2010077671A2 (en) * 2008-12-08 2010-07-08 University Of Utah Research Foundation Stable perfluorocarbon emulsion for use as an artificial oxygen carrier

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH604490A5 (es) * 1970-09-05 1978-09-15 Green Cross Corp
GB1343870A (en) * 1971-05-19 1974-01-16 Green Cross Corp Emulsions and the preparation thereof
US3911138B1 (en) * 1973-02-26 1996-10-29 Childrens Hosp Medical Center Artificial blood and method for supporting oxygen transport in animals
JPS5331209B2 (es) * 1973-10-05 1978-09-01

Also Published As

Publication number Publication date
SE7513814L (sv) 1976-06-10
FI54560B (fi) 1978-09-29
DK154605B (da) 1988-12-05
FI753442A (es) 1976-06-10
NL184995C (nl) 1990-01-02
SE8300422L (sv) 1983-01-27
CH629938A5 (en) 1982-05-28
FR2313024B1 (es) 1980-05-23
JPS5753762B2 (es) 1982-11-15
NL7514202A (nl) 1976-06-11
GB1531418A (en) 1978-11-08
FI54560C (fi) 1979-01-10
NO754103L (es) 1976-06-10
DK154605C (da) 1989-06-05
DK554675A (da) 1976-06-10
DE2555408A1 (de) 1976-06-10
SE8300422D0 (sv) 1983-01-27
JPS5198318A (es) 1976-08-30
CA1058081A (en) 1979-07-10
IT1050731B (it) 1981-03-20
FR2313024A1 (fr) 1976-12-31
NL184995B (nl) 1989-08-01

Similar Documents

Publication Publication Date Title
DE2404564C3 (de) Als Blutersatzmittel und Perfusionsflüssigkeit geeignete wässrige Emulsion und Verfahren zu ihrer Herstellung
DE69328192T4 (de) Injizierbare Arzneizubereitungen enthaltend Taxanderivate
EP0144069B1 (de) Arzneimittel mit verbesserter Penetration der Gewebsmembran
DE2834308A1 (de) Verfahren zur wasserabspaltung aus einer kolloidalen lipsomen-dispersion
DE2938807A1 (de) Fettemulsion und ihre verwendung
DE2452513B2 (de) Verfahren zur herstellung von emulsionen von fluorierten verbindungen
DE2630586A1 (de) Waessrige emulsion von perfluorkohlenstoffverbindungen mit 9 bis 11 kohlenstoffatomen, verfahren zu ihrer herstellung und ihre verwendung als blutersatzmittel und perfusionsfluessigkeit
DE2555408C2 (es)
DE3435517A1 (de) Vesikel bildende massen
EP0415263B1 (de) Stabilisierung von Perfluorcarbonemulsionen und als emulsionsstabilisierende Zusätze verwendbare perfluorierte heterocyclische Verbindungen
CH641044A5 (de) Prostacyclin und prostacyclin-derivate enthaltende pharmazeutische zubereitung und verfahren zu ihrer herstellung.
DE3303151C2 (de) Perfluorcycloamine und diese Verbindungen enthaltende Blutersatzmittel und Perfusionsflüssigkeiten
DE2743586A1 (de) Injizierbare loesung und verfahren zur herstellung derselben
CH653030A5 (de) Perfluorobicyclo-verbindungen und praeparat aus einer eine perfluorobicyclo-verbindung enthaltenden emulsion.
EP0415264B1 (de) Verfahren zur Herstellung perfluorierter heterocyclischer Verbindungen und nach diesem Verfahren hergestellte Verbindungen
CH651752A5 (de) Zwei-komponenten injektionspraeparat.
DE2224182A1 (de) Verfahren zur Herstellung einer stabilen Emulsion von Fluorkohlenstoffpartikeln
DE3406834C2 (de) Verwendung von Perfluorbromalkylethern als Röntgenkontrastmittel
DE2157400A1 (de) Anaesthetica
DE925375C (de) Verfahren zur Herstellung eines Procain-Penicillin-G-Praeparates
DE2554444C2 (de) Als Blutersatzmittel und Perfusionsflüssigkeit geeignete Emulsion
DE3139401A1 (de) "stabilisieren von polyether- oder polyester-formmassen gegen vorzeitige reaktion"
CH634227A5 (en) Injectable solution and process for the production thereof
Gross et al. Stabile Perfluorcarbon-Emulsionen/Stable Perfluorcarbon-Emulsions
EP0131927A2 (de) Pharmazeutische Zubereitung enthaltend Isosorbiddinitrat

Legal Events

Date Code Title Description
OD Request for examination
8128 New person/name/address of the agent

Representative=s name: STREHL, P., DIPL.-ING. DIPL.-WIRTSCH.-ING. SCHUEBE

D2 Grant after examination
8364 No opposition during term of opposition