DE2548883C3 - Verfahren zur photochemischen Isomerisierung von Vitamin A-Verbindungen - Google Patents

Verfahren zur photochemischen Isomerisierung von Vitamin A-Verbindungen

Info

Publication number
DE2548883C3
DE2548883C3 DE2548883A DE2548883A DE2548883C3 DE 2548883 C3 DE2548883 C3 DE 2548883C3 DE 2548883 A DE2548883 A DE 2548883A DE 2548883 A DE2548883 A DE 2548883A DE 2548883 C3 DE2548883 C3 DE 2548883C3
Authority
DE
Germany
Prior art keywords
cis
vitamin
trans
isomerization
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE2548883A
Other languages
German (de)
English (en)
Other versions
DE2548883B2 (de
DE2548883A1 (de
Inventor
Hansjörg Dr. Reinach Stoller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of DE2548883A1 publication Critical patent/DE2548883A1/de
Publication of DE2548883B2 publication Critical patent/DE2548883B2/de
Application granted granted Critical
Publication of DE2548883C3 publication Critical patent/DE2548883C3/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/06—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms
    • C07C403/08—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms by hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/06—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms
    • C07C403/10—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms by etherified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/06—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms
    • C07C403/12—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms by esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/14—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by doubly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/20—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by carboxyl groups or halides, anhydrides, or (thio)esters thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/09—Geometrical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S204/00—Chemistry: electrical and wave energy
    • Y10S204/90—Effecting a change in isomerization by wave energy

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE2548883A 1974-11-12 1975-10-31 Verfahren zur photochemischen Isomerisierung von Vitamin A-Verbindungen Expired DE2548883C3 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1508774A CH605724A5 (enExample) 1974-11-12 1974-11-12

Publications (3)

Publication Number Publication Date
DE2548883A1 DE2548883A1 (de) 1976-05-13
DE2548883B2 DE2548883B2 (de) 1981-08-06
DE2548883C3 true DE2548883C3 (de) 1982-05-13

Family

ID=4406232

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2548883A Expired DE2548883C3 (de) 1974-11-12 1975-10-31 Verfahren zur photochemischen Isomerisierung von Vitamin A-Verbindungen

Country Status (9)

Country Link
US (1) US4026778A (enExample)
JP (1) JPS5915907B2 (enExample)
AT (1) AT350743B (enExample)
BE (1) BE835334A (enExample)
CH (1) CH605724A5 (enExample)
DE (1) DE2548883C3 (enExample)
FR (1) FR2291191A1 (enExample)
GB (1) GB1527909A (enExample)
NL (1) NL7512152A (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4843096A (en) * 1985-06-26 1989-06-27 Stiefel Laboratories, Inc. Treatment of acne
TW252974B (enExample) * 1993-03-23 1995-08-01 Takeda Dharm Industry Co Ltd
WO1994022818A1 (en) * 1993-04-05 1994-10-13 Pfizer Inc. Method for the preparation of 9-cis retinoic acid
IT1274494B (it) * 1995-05-12 1997-07-17 Lab Mag Spa Procedimento fotochimico per la preparazione dell'acido 13-cis-retinoico
US5910594A (en) * 1997-02-13 1999-06-08 Roche Vitamins Inc. Process for the manufacture of 5-cyano-4-lower alkyl-oxazoles
US5908957A (en) * 1997-02-14 1999-06-01 Roche Vitamins Inc. Isomerization process
DE10344207B3 (de) 2003-09-22 2004-12-23 Schott Ag Vorrichtung und Verfahren zum Konfektionieren optischer Fasern
CN102424662B (zh) * 2011-09-28 2014-04-02 集美大学 维生素a棕榈酸酯的分离纯化方法
JP7714474B2 (ja) 2019-06-07 2025-07-29 ビーエーエスエフ ソシエタス・ヨーロピア 多価不飽和非芳香族化合物の異性化
CN119176771B (zh) * 2024-11-25 2025-01-28 济南康和医药科技有限公司 一种维生素a棕榈酸酯3种顺式异构体杂质对照品的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1053574A (enExample) * 1964-04-24
DE1468764B1 (de) * 1964-06-06 1970-01-22 Pfizer & Co C Verfahren zur Herstellung thermostabiler Gemische von Vitamin A-Isomeren und deren Estern
DE2210800C2 (de) * 1972-03-07 1974-02-21 Basf Ag, 6700 Ludwigshafen Verfahren zur photochemischen Isomerisierung von cis-Isomeren von Vitamin-A-Verbindungen und deren Derivate

Also Published As

Publication number Publication date
BE835334A (fr) 1976-05-07
DE2548883B2 (de) 1981-08-06
CH605724A5 (enExample) 1978-10-13
GB1527909A (en) 1978-10-11
US4026778A (en) 1977-05-31
DE2548883A1 (de) 1976-05-13
ATA857875A (de) 1978-11-15
AT350743B (de) 1979-06-11
FR2291191A1 (fr) 1976-06-11
JPS5915907B2 (ja) 1984-04-12
FR2291191B1 (enExample) 1978-08-18
JPS5170749A (en) 1976-06-18
NL7512152A (nl) 1976-05-14

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Legal Events

Date Code Title Description
C3 Grant after two publication steps (3rd publication)
8339 Ceased/non-payment of the annual fee