DE2529521C2 - Verfahren zur Gewinnung von 3-Hydroxysteroiden und 3-Oxosteroiden - Google Patents

Verfahren zur Gewinnung von 3-Hydroxysteroiden und 3-Oxosteroiden

Info

Publication number
DE2529521C2
DE2529521C2 DE2529521A DE2529521A DE2529521C2 DE 2529521 C2 DE2529521 C2 DE 2529521C2 DE 2529521 A DE2529521 A DE 2529521A DE 2529521 A DE2529521 A DE 2529521A DE 2529521 C2 DE2529521 C2 DE 2529521C2
Authority
DE
Germany
Prior art keywords
methyl isobutyl
calcium bromide
isobutyl ketone
mixture
adduct
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE2529521A
Other languages
German (de)
English (en)
Other versions
DE2529521A1 (de
Inventor
Johannes Dr. Kurzidim
Rudolf Dr. 1000 Berlin Müller
Alfred Dr. Weber
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Priority to DE2529521A priority Critical patent/DE2529521C2/de
Priority to DK285076A priority patent/DK144377C/da
Priority to US05/699,790 priority patent/US4057541A/en
Priority to CH817976A priority patent/CH598286A5/xx
Priority to DD193602A priority patent/DD124989A5/xx
Priority to HU76SCHE571A priority patent/HU173782B/hu
Priority to NL7607150A priority patent/NL7607150A/xx
Priority to GB27191/76A priority patent/GB1555968A/en
Priority to FR7619925A priority patent/FR2316247A1/fr
Priority to JP51077698A priority patent/JPS6019320B2/ja
Publication of DE2529521A1 publication Critical patent/DE2529521A1/de
Application granted granted Critical
Publication of DE2529521C2 publication Critical patent/DE2529521C2/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0018—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa
    • C07J1/0022—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa the substituent being an OH group free esterified or etherified

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE2529521A 1975-06-30 1975-06-30 Verfahren zur Gewinnung von 3-Hydroxysteroiden und 3-Oxosteroiden Expired DE2529521C2 (de)

Priority Applications (10)

Application Number Priority Date Filing Date Title
DE2529521A DE2529521C2 (de) 1975-06-30 1975-06-30 Verfahren zur Gewinnung von 3-Hydroxysteroiden und 3-Oxosteroiden
DK285076A DK144377C (da) 1975-06-30 1976-06-24 Fremgangsmaade til isolering af 3-hydroxysteroider og 3-oxosteroider
CH817976A CH598286A5 (US07709020-20100504-C00032.png) 1975-06-30 1976-06-25
US05/699,790 US4057541A (en) 1975-06-30 1976-06-25 Method for isolation of 3-hydroxy steroids and 3-keto steroids
DD193602A DD124989A5 (US07709020-20100504-C00032.png) 1975-06-30 1976-06-28
HU76SCHE571A HU173782B (hu) 1975-06-30 1976-06-29 Sposob razdelenija 3 - gidroksi - steroidov i/ili 3 - okso - steroidov
NL7607150A NL7607150A (nl) 1975-06-30 1976-06-30 Werkwijze voor het isoleren van 3-hydroxy- steroiden en 3-oxosteroiden.
GB27191/76A GB1555968A (en) 1975-06-30 1976-06-30 Process for the isolation of 3-hydroxy steroids and 3-oxo teroids
FR7619925A FR2316247A1 (fr) 1975-06-30 1976-06-30 Procede pour isoler des 3-hydroxysteroides et des 3-oxosteroides de melanges contenant ces composes
JP51077698A JPS6019320B2 (ja) 1975-06-30 1976-06-30 ３―ヒドロキシステロイド及び３―オクソステロイドの単離法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2529521A DE2529521C2 (de) 1975-06-30 1975-06-30 Verfahren zur Gewinnung von 3-Hydroxysteroiden und 3-Oxosteroiden

Publications (2)

Publication Number Publication Date
DE2529521A1 DE2529521A1 (de) 1977-01-27
DE2529521C2 true DE2529521C2 (de) 1984-11-29

Family

ID=5950507

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2529521A Expired DE2529521C2 (de) 1975-06-30 1975-06-30 Verfahren zur Gewinnung von 3-Hydroxysteroiden und 3-Oxosteroiden

Country Status (10)

Country Link
US (1) US4057541A (US07709020-20100504-C00032.png)
JP (1) JPS6019320B2 (US07709020-20100504-C00032.png)
CH (1) CH598286A5 (US07709020-20100504-C00032.png)
DD (1) DD124989A5 (US07709020-20100504-C00032.png)
DE (1) DE2529521C2 (US07709020-20100504-C00032.png)
DK (1) DK144377C (US07709020-20100504-C00032.png)
FR (1) FR2316247A1 (US07709020-20100504-C00032.png)
GB (1) GB1555968A (US07709020-20100504-C00032.png)
HU (1) HU173782B (US07709020-20100504-C00032.png)
NL (1) NL7607150A (US07709020-20100504-C00032.png)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4226785A (en) * 1979-10-04 1980-10-07 Eastman Kodak Company Process for dehydrogenation of sterols to produce Δ4-3-ketosteroids
US4279828A (en) * 1980-06-13 1981-07-21 Eastman Kodak Company Process for separating 3-hydroxy steroids or sterols from mixtures such as lipids
US4452994A (en) * 1981-03-02 1984-06-05 G. D. Searle & Co. Process for isolating organic compounds and lithium salt complexes useful in said process
US5045242A (en) * 1990-01-11 1991-09-03 Steven Roczniak Removal of cholesterol from edible fats
GB2338234B (en) * 1998-06-10 2000-05-03 Torcan Chemical Ltd Preparation of finasteride
WO2001032683A1 (en) 1999-11-01 2001-05-10 Torcan Chemical Ltd. Production of polymorphic forms i and ii of finasteride by complexation with group i or ii metal salts
CN100387611C (zh) * 2006-02-23 2008-05-14 中国科学院上海有机化学研究所 一类16α-溴代甾体化合物及其合成方法
CN101250211B (zh) * 2008-04-02 2010-12-22 中国科学院上海有机化学研究所 一类孕甾-16-烯-20s-乙酸酯化合物及其合成方法
FR2978452B1 (fr) * 2011-07-28 2015-01-30 Expanscience Lab Extraction liquide / liquide avec un solvant comprenant au moins 5 atomes de carbone et 1 ou 2 atomes d'oxygene

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2568202A (en) * 1941-11-28 1951-09-18 Veenendaalsche Sajet En Vijfsc Process for recovering sterols from mixtures thereof
US3450541A (en) * 1966-06-29 1969-06-17 Us Agriculture Rapid quantitative removal of natural sterols from lipids
NL127423C (US07709020-20100504-C00032.png) * 1967-05-11
US3983147A (en) * 1973-06-12 1976-09-28 Dai-Ichi Kogyo Seiyaku Co., Ltd. Separation of wool fatty acid

Also Published As

Publication number Publication date
CH598286A5 (US07709020-20100504-C00032.png) 1978-04-28
DK144377B (da) 1982-03-01
DK144377C (da) 1982-07-26
DD124989A5 (US07709020-20100504-C00032.png) 1977-03-23
HU173782B (hu) 1979-08-28
DK285076A (da) 1976-12-31
JPS527951A (en) 1977-01-21
FR2316247B1 (US07709020-20100504-C00032.png) 1980-05-09
DE2529521A1 (de) 1977-01-27
US4057541A (en) 1977-11-08
GB1555968A (en) 1979-11-14
FR2316247A1 (fr) 1977-01-28
JPS6019320B2 (ja) 1985-05-15
NL7607150A (nl) 1977-01-03

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
D2 Grant after examination
8364 No opposition during term of opposition