DE2514912A1 - Cephalosporine mit alpha-acyloxyessigsaeureseitenkette - Google Patents

Cephalosporine mit alpha-acyloxyessigsaeureseitenkette

Info

Publication number
DE2514912A1
DE2514912A1 DE19752514912 DE2514912A DE2514912A1 DE 2514912 A1 DE2514912 A1 DE 2514912A1 DE 19752514912 DE19752514912 DE 19752514912 DE 2514912 A DE2514912 A DE 2514912A DE 2514912 A1 DE2514912 A1 DE 2514912A1
Authority
DE
Germany
Prior art keywords
formula
group
hydrogen
hydroxy
salts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE19752514912
Other languages
German (de)
English (en)
Inventor
Hans Dr Bickel
Karoly Dr Kocsis
Heinrich Dr Peter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of DE2514912A1 publication Critical patent/DE2514912A1/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/50—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/557—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. orotic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/06—1,2,4-Triazines
    • C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
    • C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D253/075—Two hetero atoms, in positions 3 and 5

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE19752514912 1974-04-11 1975-04-05 Cephalosporine mit alpha-acyloxyessigsaeureseitenkette Pending DE2514912A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH517974 1974-04-11

Publications (1)

Publication Number Publication Date
DE2514912A1 true DE2514912A1 (de) 1975-10-23

Family

ID=4289231

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19752514912 Pending DE2514912A1 (de) 1974-04-11 1975-04-05 Cephalosporine mit alpha-acyloxyessigsaeureseitenkette

Country Status (12)

Country Link
US (1) US4067979A (enExample)
JP (1) JPS50142590A (enExample)
AT (1) ATA271875A (enExample)
AU (1) AU7998475A (enExample)
BE (1) BE827783A (enExample)
DE (1) DE2514912A1 (enExample)
DK (1) DK155175A (enExample)
FR (1) FR2274306A1 (enExample)
IL (1) IL47069A0 (enExample)
NL (1) NL7504354A (enExample)
SE (1) SE7503274L (enExample)
ZA (1) ZA752295B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0010313A1 (en) * 1978-10-24 1980-04-30 Fujisawa Pharmaceutical Co., Ltd. 3,7-Disubstituted-2- or -3-cephem-4-carboxylic acid compounds, pharmaceutical compositions containing them and processes for the preparation thereof

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04133653U (ja) * 1991-05-29 1992-12-11 株式会社日本アレフ カードストツカ
US9573908B2 (en) 2012-02-27 2017-02-21 The Trustees Of Princeton University Broad spectrum pro-quorum-sensing molecules as inhibitors of virulence in vibrios

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3812116A (en) * 1971-07-02 1974-05-21 Fujisawa Pharmaceutical Co 7-acylated 3-substituted cephalosporin compounds
US4000133A (en) * 1973-06-06 1976-12-28 Fujisawa Pharmaceutical Co., Ltd. Substituted 7-styryl-carbonyloxy-acetamido cephalosporanic
US4006138A (en) * 1975-04-11 1977-02-01 Eli Lilly And Company Crystalline form of sodium O-formylcefamandole

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0010313A1 (en) * 1978-10-24 1980-04-30 Fujisawa Pharmaceutical Co., Ltd. 3,7-Disubstituted-2- or -3-cephem-4-carboxylic acid compounds, pharmaceutical compositions containing them and processes for the preparation thereof

Also Published As

Publication number Publication date
AU7998475A (en) 1976-10-14
ZA752295B (en) 1976-03-31
NL7504354A (nl) 1975-10-14
DK155175A (enExample) 1975-10-12
ATA271875A (de) 1976-12-15
SE7503274L (sv) 1975-10-13
BE827783A (fr) 1975-10-10
IL47069A0 (en) 1975-06-25
US4067979A (en) 1978-01-10
JPS50142590A (enExample) 1975-11-17
FR2274306A1 (fr) 1976-01-09

Similar Documents

Publication Publication Date Title
EP0064740B1 (de) Cephalosporinderivate und Verfahren zu ihrer Herstellung
DE2520561A1 (de) Cephalosporine mit alpha-acylaminoessigsaeureseitenkette
US4464367A (en) Cephalosporin derivatives, process for preparation thereof and drugs containing said derivatives usable as antibiotics
CH630923A5 (de) Verfahren zur herstellung von neuen cephalosporinderivaten.
DE2347533A1 (de) Neue derivate der penam-3-carbonsaeure und cephem-4-carbonsaeure und verfahren zu ihrer herstellung
DE2744135A1 (de) Cephalosporinderivate, verfahren zu deren herstellung und diese enthaltende arzneimittel
DD210279A5 (de) Verfahren zur herstellung von cephalosporinverbindungen
DE2462376A1 (de) Antibiotika und verfahren zu ihrer herstellung
EP0137441A2 (de) Cephalosporinderivate und Verfahren zu ihrer Herstellung
DE2758001A1 (de) Cephalosporinderivate und verfahren zu ihrer herstellung
CH647784A5 (de) Cephalosporinantibiotika.
EP0111934A2 (de) Cephalosporinderivate und Verfahren zu ihrer Herstellung
EP0000392B1 (de) Cephalosporin und Penicillin-derivate, Verfahren zu deren Herstellung, und deren pharmazeutische Präparate
DE3247614A1 (de) Cephalosporinderivate und verfahren zu ihrer herstellung
DE2514912A1 (de) Cephalosporine mit alpha-acyloxyessigsaeureseitenkette
DE2313667A1 (de) Neue derivate der penam-3-carbonsaeure und cephem-4-carbonsaeure und verfahren zu ihrer herstellung
CH649557A5 (de) Cephalosporinantibiotika.
CH637139A5 (de) Verfahren zur herstellung von cephalosporinverbindungen.
AT391319B (de) Verfahren zur herstellung von neuen cephalosporinverbindungen
EP0008343B1 (de) Cephalosporinderivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Präparate
EP0064256B1 (de) Cephemderivate und Verfahren zu ihrer Herstellung
CH644867A5 (de) In der 3- und 7-stellung substituierte cephemcarbonsaeuren.
US3953439A (en) Substituted phenylglycylcephalosporins
US4154831A (en) Cephalosporins having an α-acylaminoacetic acid side chain
EP0000005A1 (de) Neue Cephalosporinderivate, Verfahren zu ihrer Herstellung und pharmazeutische Präparate