AU7998475A - Process for the manufacture of cephalosporins having an alpha-acyloxyacetic acid side chain - Google Patents

Process for the manufacture of cephalosporins having an alpha-acyloxyacetic acid side chain

Info

Publication number
AU7998475A
AU7998475A AU79984/75A AU7998475A AU7998475A AU 7998475 A AU7998475 A AU 7998475A AU 79984/75 A AU79984/75 A AU 79984/75A AU 7998475 A AU7998475 A AU 7998475A AU 7998475 A AU7998475 A AU 7998475A
Authority
AU
Australia
Prior art keywords
cephalosporins
alpha
manufacture
side chain
acid side
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU79984/75A
Other languages
English (en)
Inventor
Hans Bickel
Karoly Kocsis
Heinrich Peter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of AU7998475A publication Critical patent/AU7998475A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/50—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/557—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. orotic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/06—1,2,4-Triazines
    • C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
    • C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D253/075—Two hetero atoms, in positions 3 and 5

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU79984/75A 1974-04-11 1975-04-09 Process for the manufacture of cephalosporins having an alpha-acyloxyacetic acid side chain Expired AU7998475A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH517974 1974-04-11

Publications (1)

Publication Number Publication Date
AU7998475A true AU7998475A (en) 1976-10-14

Family

ID=4289231

Family Applications (1)

Application Number Title Priority Date Filing Date
AU79984/75A Expired AU7998475A (en) 1974-04-11 1975-04-09 Process for the manufacture of cephalosporins having an alpha-acyloxyacetic acid side chain

Country Status (12)

Country Link
US (1) US4067979A (enExample)
JP (1) JPS50142590A (enExample)
AT (1) ATA271875A (enExample)
AU (1) AU7998475A (enExample)
BE (1) BE827783A (enExample)
DE (1) DE2514912A1 (enExample)
DK (1) DK155175A (enExample)
FR (1) FR2274306A1 (enExample)
IL (1) IL47069A0 (enExample)
NL (1) NL7504354A (enExample)
SE (1) SE7503274L (enExample)
ZA (1) ZA752295B (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4327093A (en) * 1978-10-24 1982-04-27 Fujisawa Pharmaceutical Co., Ltd. 3,7-Disubstituted-2 or 3-cephem-4-carboxylic acid compounds
JPH04133653U (ja) * 1991-05-29 1992-12-11 株式会社日本アレフ カードストツカ
WO2014092751A1 (en) * 2012-02-27 2014-06-19 The Trustees Of Princeton University Broad spectrum pro-quorum-sensing molecules as inhibitors of virulence in vibrios

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3812116A (en) * 1971-07-02 1974-05-21 Fujisawa Pharmaceutical Co 7-acylated 3-substituted cephalosporin compounds
US4000133A (en) * 1973-06-06 1976-12-28 Fujisawa Pharmaceutical Co., Ltd. Substituted 7-styryl-carbonyloxy-acetamido cephalosporanic
US4006138A (en) * 1975-04-11 1977-02-01 Eli Lilly And Company Crystalline form of sodium O-formylcefamandole

Also Published As

Publication number Publication date
NL7504354A (nl) 1975-10-14
BE827783A (fr) 1975-10-10
FR2274306A1 (fr) 1976-01-09
US4067979A (en) 1978-01-10
ZA752295B (en) 1976-03-31
ATA271875A (de) 1976-12-15
IL47069A0 (en) 1975-06-25
DK155175A (enExample) 1975-10-12
DE2514912A1 (de) 1975-10-23
SE7503274L (sv) 1975-10-13
JPS50142590A (enExample) 1975-11-17

Similar Documents

Publication Publication Date Title
YU39941B (en) Process for obtaining clavulanic acid
GB1520798A (en) Process for the production of 2 - aryl - 2h - benzotriazoles
YU96075A (en) Process for the manufacture of thienyl and thiethyl compounds
YU43130B (en) Process for producing 7-d-/-/-alpha-amino-alpha-/p-hydroxy-phenylacetamido/dezacetoxy cephalosporanic acid
CA1030556A (en) Process for the production of hydroxy-pivaldehyde
IL48639A0 (en) Process for the production of carbonylaldiminomethanephosphonates
GB1484231A (en) Process for the preparation of 7-amino-cephalosporanic acids
IL47550A0 (en) The production of phosphoric acid
ZA754972B (en) Process for the manufacture of bromine
YU143875A (en) Process for producing 6-d-(-)-delta-amino-delta-(p-acetoxyphenylacetamido)-penicillanic acid
CH613971A5 (en) Process for the purification of 7-acylamido- or 7-amino-3-(substituted)-3-cephemcarboxylic acids
ZA754863B (en) Process for the manufacture of resorcinol
ZA755177B (en) Process for the preparation of cephalosporins
ZA752065B (en) Process for the manufacture of salts of poly-alpha- hydroxyacrylic acid
ZA752295B (en) Process for the manufacture of cephalosporins having an alpha-acyloxyacetic acid side chain
IE40460B1 (en) Process for the production of phosphorus pentachloride
ZA757523B (en) Process for the production of jodophors
YU35875B (en) Process for the manufacture of a substituted s-alkyl-thiocarbamate
ZA75920B (en) Process for the manufacture of 5-sulfamoyl-anthranilic acids
ZA755031B (en) Process for making cephalosporins
IL46646A0 (en) The production of cephem compounds
ZA75188B (en) Process for the manufacture of beer
GB1522477A (en) Process for the manufacture of rho-hydroxybenzyl cyanide
KE2800A (en) Process for the manufacture of 6-id(-)-alpha-aminophenylacetamido/-penicillanic acid
JPS51125045A (en) Process for manufacture of pgf betaaprostaglandins