DE2512284A1 - Cephalosporansaeurederivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische mittel - Google Patents

Cephalosporansaeurederivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische mittel

Info

Publication number
DE2512284A1
DE2512284A1 DE19752512284 DE2512284A DE2512284A1 DE 2512284 A1 DE2512284 A1 DE 2512284A1 DE 19752512284 DE19752512284 DE 19752512284 DE 2512284 A DE2512284 A DE 2512284A DE 2512284 A1 DE2512284 A1 DE 2512284A1
Authority
DE
Germany
Prior art keywords
hydrogen
phenyl
compound according
heterocyclic
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19752512284
Other languages
German (de)
English (en)
Inventor
Susumu Horibe
Tadayoshi Takano
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astellas Pharma Inc
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP3608074A external-priority patent/JPS5833236B2/ja
Priority claimed from JP4057774A external-priority patent/JPS5729473B2/ja
Priority claimed from JP4113074A external-priority patent/JPS5729476B2/ja
Priority claimed from JP4151574A external-priority patent/JPS5729475B2/ja
Priority claimed from JP4151674A external-priority patent/JPS5729477B2/ja
Priority claimed from JP4256874A external-priority patent/JPS5833237B2/ja
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Publication of DE2512284A1 publication Critical patent/DE2512284A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
DE19752512284 1974-03-28 1975-03-20 Cephalosporansaeurederivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische mittel Withdrawn DE2512284A1 (de)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP3608074A JPS5833236B2 (ja) 1974-03-28 1974-03-28 ７−（ アルフア − チカンアミノアルカンアミド ）−３− チカン −３− セフエム −４− カルボンサンユウドウタイノ セイゾウホウ
JP4057774A JPS5729473B2 (cg-RX-API-DMAC10.html) 1974-04-09 1974-04-09
JP4113074A JPS5729476B2 (cg-RX-API-DMAC10.html) 1974-04-10 1974-04-10
JP4151574A JPS5729475B2 (cg-RX-API-DMAC10.html) 1974-04-11 1974-04-11
JP4151674A JPS5729477B2 (cg-RX-API-DMAC10.html) 1974-04-11 1974-04-11
JP4256874A JPS5833237B2 (ja) 1974-04-15 1974-04-15 ７−（ アルフア− − チカンアミノアルカンアミド ）−３− チカン −３− セフエム −４− カルボンサンユウドウタイノ セイホウ

Publications (1)

Publication Number Publication Date
DE2512284A1 true DE2512284A1 (de) 1975-10-09

Family

ID=27549794

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19752512284 Withdrawn DE2512284A1 (de) 1974-03-28 1975-03-20 Cephalosporansaeurederivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische mittel

Country Status (4)

Country Link
US (2) US4039536A (cg-RX-API-DMAC10.html)
DE (1) DE2512284A1 (cg-RX-API-DMAC10.html)
FR (1) FR2265390B1 (cg-RX-API-DMAC10.html)
GB (1) GB1488591A (cg-RX-API-DMAC10.html)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4576937A (en) * 1984-02-29 1986-03-18 Smithkline Beckman Corporation 7-D-Mandelamido-3(1-sulfomethyltetrazol-5-yl)thiomethyl-3-cephem-4-carboxylic acid monosodium salt

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2512284A1 (de) * 1974-03-28 1975-10-09 Fujisawa Pharmaceutical Co Cephalosporansaeurederivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische mittel
US4091217A (en) * 1974-05-28 1978-05-23 Toshiyasu Ishimaru 7-((5'-N-Methylthioacetamido)-adipoamido)cephalosporin derivatives
JPS5760345B2 (cg-RX-API-DMAC10.html) * 1974-12-19 1982-12-18 Takeda Chemical Industries Ltd
DK154939C (da) * 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
US4183925A (en) * 1975-03-27 1980-01-15 Pfizer Inc. 7-Aminophenylacetamido-Δ3 -cephem antibacterial agents and method of use
US4171433A (en) * 1975-10-30 1979-10-16 Smithkline Corporation 7-Amino-3-(sulfaminoalkyl substituted tetrazolylthiomethyl)cephalosporin intermediates for preparing 7-acylamino cephalosporins
US4171362A (en) * 1975-10-30 1979-10-16 Smithkline Corporation 7-Acylamino-3-(sulfaminoalkyl substituted tetrazolylthiomethyl)cephalosporins antibacterial compositions containing them and methods of treating bacterial infections with them
US4171368A (en) * 1975-10-30 1979-10-16 Smithkline Corporation 7-Acylamino-3-(sulfaminoalkyl substituted tetrazolylthiomethyl)cephalosporins, antibacterial compositions containing them and methods of treating bacterial infections with them
GB1579532A (en) * 1976-05-21 1980-11-19 Farmaceutici Italia Cephalosporins
DE2724073A1 (de) * 1976-06-03 1977-12-22 Fujisawa Pharmaceutical Co 3,7-disubstituierte 3-cephem-4- carbonsaeuren und sie enthaltende pharmazeutische zubereitungen
CH634848A5 (de) * 1976-08-17 1983-02-28 Fujisawa Pharmaceutical Co Verfahren zur herstellung neuer 7-(n-substituierter 2-phenylglycinamido)-3-substituierte-3-cephem-4-carbonsaeuren.
JPS5874680A (ja) * 1981-10-01 1983-05-06 Kyowa Hakko Kogyo Co Ltd β−ラクタム化合物
IT1265061B1 (it) * 1993-08-06 1996-10-28 Dompe Spa Valilamidi di 7alfa-amino-1, 1-dioxo-cefem

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3222362A (en) * 1961-08-23 1965-12-07 Lilly Co Eli Arylaminoalkyl cephalosporins
FR1438747A (fr) * 1965-06-21 1966-05-13 Acides (pyridine-carbonamido)-7 céphalosporaniques
US3592812A (en) * 1968-12-06 1971-07-13 American Home Prod 7-(1-aminocycloalkylcarboxamido) cephalosporanic acids and related compounds
US3673183A (en) * 1969-11-17 1972-06-27 Squibb & Sons Inc {60 -ureidocephalosporanic acid compounds
US3867380A (en) * 1971-02-18 1975-02-18 Smithkline Corp 3-Heterocyclic thiomethylcephalosporins
US3796801A (en) * 1971-11-04 1974-03-12 Smithkline Corp Method of combating enterobacter infections
BE793191A (fr) * 1971-12-28 1973-06-22 Toyama Chemical Co Ltd Procede pour produire des acides 7-acylamido-3-cephem-4- carboxyliques
US3799923A (en) * 1972-01-03 1974-03-26 Fujisawa Pharmaceutical Co 3-thiolated cephalosporin derivatives and production of same
US3840531A (en) * 1972-03-21 1974-10-08 Lilly Co Eli Process for preparing 7-(alpha-hydroxy-alpha-phenyl)acetamido-3-(1-methyl-1h-tetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid and derivatives thereof
US3966718A (en) * 1973-01-18 1976-06-29 Beecham Group Limited 7-β-Acylamino-ceph-3-ems and salts and esters therefor
DE2512284A1 (de) * 1974-03-28 1975-10-09 Fujisawa Pharmaceutical Co Cephalosporansaeurederivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische mittel
GB1505345A (en) * 1974-04-10 1978-03-30 Beecham Group Ltd Cephalosporins

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4576937A (en) * 1984-02-29 1986-03-18 Smithkline Beckman Corporation 7-D-Mandelamido-3(1-sulfomethyltetrazol-5-yl)thiomethyl-3-cephem-4-carboxylic acid monosodium salt

Also Published As

Publication number Publication date
GB1488591A (en) 1977-10-12
FR2265390A1 (cg-RX-API-DMAC10.html) 1975-10-24
US4039536A (en) 1977-08-02
FR2265390B1 (cg-RX-API-DMAC10.html) 1978-07-28
US4252952A (en) 1981-02-24

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
8139 Disposal/non-payment of the annual fee