DE2511599C3 - 3,7-Dihydro-5-phenyl-6-methyl- pyrrole [3,4-e] [1,4] diazepin-2 (lH)-one, Verfahren zu ihrer Herstellung und Arzneimittel - Google Patents

3,7-Dihydro-5-phenyl-6-methyl- pyrrole [3,4-e] [1,4] diazepin-2 (lH)-one, Verfahren zu ihrer Herstellung und Arzneimittel

Info

Publication number
DE2511599C3
DE2511599C3 DE2511599A DE2511599A DE2511599C3 DE 2511599 C3 DE2511599 C3 DE 2511599C3 DE 2511599 A DE2511599 A DE 2511599A DE 2511599 A DE2511599 A DE 2511599A DE 2511599 C3 DE2511599 C3 DE 2511599C3
Authority
DE
Germany
Prior art keywords
dihydro
diazepin
ones
phenyl
methylpyrroles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE2511599A
Other languages
German (de)
English (en)
Other versions
DE2511599A1 (de
DE2511599B2 (de
Inventor
Luigi Fontanella
Luigi Mariani
Giorgio Rom Tarzia
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gruppo Lepetit SpA
Original Assignee
Gruppo Lepetit SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruppo Lepetit SpA filed Critical Gruppo Lepetit SpA
Publication of DE2511599A1 publication Critical patent/DE2511599A1/de
Publication of DE2511599B2 publication Critical patent/DE2511599B2/de
Application granted granted Critical
Publication of DE2511599C3 publication Critical patent/DE2511599C3/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
DE2511599A 1974-03-20 1975-03-17 3,7-Dihydro-5-phenyl-6-methyl- pyrrole [3,4-e] [1,4] diazepin-2 (lH)-one, Verfahren zu ihrer Herstellung und Arzneimittel Expired DE2511599C3 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1238875A GB1433103A (en) 1974-03-20 1974-03-20 Pharmacologically active pyrrolodiazepines

Publications (3)

Publication Number Publication Date
DE2511599A1 DE2511599A1 (de) 1975-09-25
DE2511599B2 DE2511599B2 (de) 1979-08-09
DE2511599C3 true DE2511599C3 (de) 1980-04-10

Family

ID=10003647

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2511599A Expired DE2511599C3 (de) 1974-03-20 1975-03-17 3,7-Dihydro-5-phenyl-6-methyl- pyrrole [3,4-e] [1,4] diazepin-2 (lH)-one, Verfahren zu ihrer Herstellung und Arzneimittel

Country Status (9)

Country Link
US (1) US4022766A (enExample)
JP (1) JPS5333599B2 (enExample)
BE (1) BE826925A (enExample)
CA (1) CA1063106A (enExample)
DE (1) DE2511599C3 (enExample)
DK (1) DK140372B (enExample)
FR (1) FR2264546B1 (enExample)
GB (1) GB1433103A (enExample)
NL (1) NL162077C (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR76455B (enExample) * 1981-06-04 1984-08-10 Lepetit Spa
IT1167788B (it) * 1981-06-08 1987-05-13 Lepetit Spa Derivati pirrolo-diazepinici
JPS58110158U (ja) * 1982-01-22 1983-07-27 第一技建株式会社 開閉窓のロツク装置
US4508730A (en) * 1982-09-08 1985-04-02 Gruppo Lepetit S.P.A. 1,7-Dihydro-pyrrolo[3,4-e][1,4]diazepin-2(3H)-one derivatives a process for preparing them and their use as anticonvulsant and anti-anxiety agents
US4517195A (en) * 1984-07-02 1985-05-14 Hoechst-Roussel Pharmaceuticals Inc. Pyrrolo[1,2-b][1,2,5]triazepines and pharmaceutical compositions thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3202699A (en) * 1961-07-11 1965-08-24 Hoffmann La Roche Carbobenzoxyglycylamino-benzophenones
US3534021A (en) * 1968-05-20 1970-10-13 Hoffmann La Roche Methylation of 1,4-benzodiazepines
US3682892A (en) * 1970-12-23 1972-08-08 Hoffmann La Roche 7-hydroxy lower alkyl benzodiazepines
US3764688A (en) * 1972-07-27 1973-10-09 Abbott Lab 4,6-DIHYDRO-1,3-DIMETHYL-8-PHENYL-4-PROPARGYL-PYRAZOLO {8 4,3-e{9 {0 DIAZEPIN-5 (1H) ONE IN TREATING INFLAMMATION

Also Published As

Publication number Publication date
JPS50135094A (enExample) 1975-10-25
FR2264546B1 (enExample) 1978-07-28
FR2264546A1 (enExample) 1975-10-17
CA1063106A (en) 1979-09-25
DK140372C (enExample) 1980-01-14
JPS5333599B2 (enExample) 1978-09-14
DE2511599A1 (de) 1975-09-25
BE826925A (fr) 1975-07-16
NL162077C (nl) 1980-04-15
US4022766A (en) 1977-05-10
DK111475A (enExample) 1975-09-21
NL7503253A (nl) 1975-09-23
GB1433103A (en) 1976-04-22
DK140372B (da) 1979-08-13
DE2511599B2 (de) 1979-08-09

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Legal Events

Date Code Title Description
C3 Grant after two publication steps (3rd publication)
8339 Ceased/non-payment of the annual fee