DE2505002A1 - Beta-naphthylmethyl-4-piperazine, verfahren zu ihrer herstellung und arzneimittel - Google Patents

Beta-naphthylmethyl-4-piperazine, verfahren zu ihrer herstellung und arzneimittel

Info

Publication number
DE2505002A1
DE2505002A1 DE19752505002 DE2505002A DE2505002A1 DE 2505002 A1 DE2505002 A1 DE 2505002A1 DE 19752505002 DE19752505002 DE 19752505002 DE 2505002 A DE2505002 A DE 2505002A DE 2505002 A1 DE2505002 A1 DE 2505002A1
Authority
DE
Germany
Prior art keywords
piperazine
acid
naphthylmethyl
general formula
chloromethylnaphthalene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
DE19752505002
Other languages
German (de)
English (en)
Inventor
Harlan Ford Hill
John Joseph Lafferty
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlaxoSmithKline LLC
Original Assignee
SmithKline Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Corp filed Critical SmithKline Corp
Publication of DE2505002A1 publication Critical patent/DE2505002A1/de
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/03Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/06Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
    • C07D295/073Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
DE19752505002 1974-02-07 1975-02-06 Beta-naphthylmethyl-4-piperazine, verfahren zu ihrer herstellung und arzneimittel Ceased DE2505002A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US440431A US3919230A (en) 1974-02-07 1974-02-07 {62 -Naphthylmethyl piperazinyl derivatives

Publications (1)

Publication Number Publication Date
DE2505002A1 true DE2505002A1 (de) 1975-08-14

Family

ID=23748733

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19752505002 Ceased DE2505002A1 (de) 1974-02-07 1975-02-06 Beta-naphthylmethyl-4-piperazine, verfahren zu ihrer herstellung und arzneimittel

Country Status (16)

Country Link
US (1) US3919230A (es)
JP (1) JPS50108278A (es)
AU (1) AU501049B2 (es)
BE (1) BE825178A (es)
CA (1) CA1042434A (es)
CH (1) CH616678A5 (es)
DE (1) DE2505002A1 (es)
ES (1) ES434433A1 (es)
FR (1) FR2260353B1 (es)
GB (1) GB1449802A (es)
HU (1) HU171352B (es)
IE (1) IE40593B1 (es)
IL (1) IL46568A (es)
LU (1) LU71803A1 (es)
NL (1) NL7501362A (es)
ZA (1) ZA75160B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4130646A (en) * 1975-07-25 1978-12-19 E. R. Squibb & Sons, Inc. 1,2,3,4-Tetrahydro-2-((4-(phenyl)-1-piperazinyl)methyl)-1-naphthalenols and derivatives and analogs thereof
JPS52133993A (en) * 1976-04-29 1977-11-09 Takeda Chem Ind Ltd 1.2-dihydronaphthalene derivatives and method of preparing the same
US4367335A (en) * 1981-08-03 1983-01-04 Mead Johnson & Company Thiazolidinylalkylene piperazine derivatives
US4620006A (en) * 1982-08-11 1986-10-28 Eastman Kodak Company Acid salts of 1-(cyanoalkyl)-4-guanylpiperazines
WO2000051547A2 (en) * 1999-03-03 2000-09-08 Merck & Co., Inc. Inhibitors of prenyl-protein transferase
CN107652156B (zh) * 2017-11-18 2023-11-10 辽宁科技学院 一种β-甲基萘的结晶方法和装置

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL127996C (es) * 1963-11-19

Also Published As

Publication number Publication date
LU71803A1 (es) 1975-06-24
CH616678A5 (es) 1980-04-15
FR2260353B1 (es) 1980-01-04
HU171352B (hu) 1977-12-28
AU501049B2 (en) 1979-06-07
NL7501362A (nl) 1975-08-11
IE40593B1 (en) 1979-07-04
ZA75160B (en) 1976-01-28
IL46568A (en) 1979-01-31
BE825178A (fr) 1975-08-04
IE40593L (en) 1975-08-07
ES434433A1 (es) 1976-11-16
JPS50108278A (es) 1975-08-26
FR2260353A1 (es) 1975-09-05
IL46568A0 (en) 1975-04-25
GB1449802A (en) 1976-09-15
US3919230A (en) 1975-11-11
AU7784075A (en) 1976-08-05
CA1042434A (en) 1978-11-14

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Legal Events

Date Code Title Description
E77 Valid patent as to the heymanns-index 1977
8110 Request for examination paragraph 44
8131 Rejection