DE2504045C3 - 16,17 Dihydro-apovincaminsäure-2hydroxypropylester, deren Salze, Verfahren zu ihrer Herstellung und Arzneimittel - Google Patents

16,17 Dihydro-apovincaminsäure-2hydroxypropylester, deren Salze, Verfahren zu ihrer Herstellung und Arzneimittel

Info

Publication number
DE2504045C3
DE2504045C3 DE2504045A DE2504045A DE2504045C3 DE 2504045 C3 DE2504045 C3 DE 2504045C3 DE 2504045 A DE2504045 A DE 2504045A DE 2504045 A DE2504045 A DE 2504045A DE 2504045 C3 DE2504045 C3 DE 2504045C3
Authority
DE
Germany
Prior art keywords
acid
dihydro
general formula
salts
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE2504045A
Other languages
German (de)
English (en)
Other versions
DE2504045B2 (de
DE2504045A1 (de
Inventor
Monique Plat Geb. Berry
Michel Marie Rene Plat
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo SA filed Critical Synthelabo SA
Publication of DE2504045A1 publication Critical patent/DE2504045A1/de
Publication of DE2504045B2 publication Critical patent/DE2504045B2/de
Application granted granted Critical
Publication of DE2504045C3 publication Critical patent/DE2504045C3/de
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D461/00Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE2504045A 1974-01-31 1975-01-31 16,17 Dihydro-apovincaminsäure-2hydroxypropylester, deren Salze, Verfahren zu ihrer Herstellung und Arzneimittel Expired DE2504045C3 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7403167A FR2259612B1 (US20040232935A1-20041125-M00001.png) 1974-01-31 1974-01-31

Publications (3)

Publication Number Publication Date
DE2504045A1 DE2504045A1 (de) 1975-08-07
DE2504045B2 DE2504045B2 (de) 1977-10-06
DE2504045C3 true DE2504045C3 (de) 1978-06-01

Family

ID=9134254

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2504045A Expired DE2504045C3 (de) 1974-01-31 1975-01-31 16,17 Dihydro-apovincaminsäure-2hydroxypropylester, deren Salze, Verfahren zu ihrer Herstellung und Arzneimittel

Country Status (18)

Country Link
US (1) US3987049A (US20040232935A1-20041125-M00001.png)
JP (1) JPS5312520B2 (US20040232935A1-20041125-M00001.png)
BE (1) BE825088A (US20040232935A1-20041125-M00001.png)
CA (1) CA1039284A (US20040232935A1-20041125-M00001.png)
CH (1) CH603650A5 (US20040232935A1-20041125-M00001.png)
DE (1) DE2504045C3 (US20040232935A1-20041125-M00001.png)
DK (1) DK32075A (US20040232935A1-20041125-M00001.png)
ES (1) ES434304A1 (US20040232935A1-20041125-M00001.png)
FI (1) FI750277A (US20040232935A1-20041125-M00001.png)
FR (1) FR2259612B1 (US20040232935A1-20041125-M00001.png)
GB (1) GB1445956A (US20040232935A1-20041125-M00001.png)
HU (1) HU170634B (US20040232935A1-20041125-M00001.png)
IL (1) IL46539A0 (US20040232935A1-20041125-M00001.png)
LU (1) LU71776A1 (US20040232935A1-20041125-M00001.png)
NL (1) NL7501172A (US20040232935A1-20041125-M00001.png)
NO (1) NO750294L (US20040232935A1-20041125-M00001.png)
SE (1) SE7500949L (US20040232935A1-20041125-M00001.png)
ZA (1) ZA75661B (US20040232935A1-20041125-M00001.png)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU171163B (hu) * 1974-09-27 1977-11-28 Richter Gedeon Vegyeszet Sposob poluchenija proizvodnykh trans eburnamenina
HU171663B (hu) * 1975-09-01 1978-02-28 Richter Gedeon Vegyeszet Sposob poluchenija novykh proizvodnykh 14-skobka-zamehhennogo metil-skobka zakryta-vinkana
FR2459799A1 (fr) * 1979-06-22 1981-01-16 Synthelabo Synthese de la ()-vincamine
YU41200B (en) * 1980-02-29 1986-12-31 Lek Tovarna Farmacevtskih Process for preparing vincamine acid esters and derivatives thereof
JPS56161388A (en) * 1980-05-16 1981-12-11 Nippon Zoki Pharmaceut Co Ltd Novel vincamine derivative
IT1148733B (it) * 1980-11-14 1986-12-03 Medea Res Srl Derivati della vincamina,metodo per la sua preparazione e composizione farmaceutiche che lo contengono
JPS5820471U (ja) * 1981-07-31 1983-02-08 ソニー株式会社 電池の逆接続防止装置
JPS5820472U (ja) * 1981-07-31 1983-02-08 ソニー株式会社 電池の逆装填防止装置
HU198207B (en) * 1985-04-19 1989-08-28 Richter Gedeon Vegyeszet Process for production of derivatives of eburnamenin and medical compositions containing them
JPS62142154U (US20040232935A1-20041125-M00001.png) * 1986-03-01 1987-09-08
CN114249721B (zh) * 2021-11-29 2023-10-17 南京中医药大学 长春胺peg衍生物与在制备治疗糖尿病周围神经病变、糖尿病足及肺纤维化药物中的应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3770724A (en) * 1970-03-31 1973-11-06 Roussel Uclaf Process for preparing pentacyclic alkaloids
BE790837A (fr) * 1971-11-03 1973-02-15 Richter Gedeon Vegeon Vegyesze Nouveaux esters alcaloides utiles comme vasodilatateurs cerebraux et leur procede de preparation
FR2179620B1 (US20040232935A1-20041125-M00001.png) * 1972-04-14 1975-12-26 Roussel Uclaf
US3852453A (en) * 1972-05-26 1974-12-03 Synthelabo Method of enhancing vincamine compositions

Also Published As

Publication number Publication date
CA1039284A (en) 1978-09-26
HU170634B (US20040232935A1-20041125-M00001.png) 1977-07-28
CH603650A5 (US20040232935A1-20041125-M00001.png) 1978-08-31
AU7777175A (en) 1976-08-05
FR2259612A1 (US20040232935A1-20041125-M00001.png) 1975-08-29
DK32075A (US20040232935A1-20041125-M00001.png) 1975-09-29
LU71776A1 (US20040232935A1-20041125-M00001.png) 1975-12-09
ZA75661B (en) 1976-01-28
FI750277A (US20040232935A1-20041125-M00001.png) 1975-08-01
DE2504045B2 (de) 1977-10-06
ES434304A1 (es) 1976-12-01
JPS5312520B2 (US20040232935A1-20041125-M00001.png) 1978-05-01
DE2504045A1 (de) 1975-08-07
SE7500949L (US20040232935A1-20041125-M00001.png) 1975-08-01
US3987049A (en) 1976-10-19
FR2259612B1 (US20040232935A1-20041125-M00001.png) 1977-09-09
JPS50112399A (US20040232935A1-20041125-M00001.png) 1975-09-03
GB1445956A (en) 1976-08-11
NL7501172A (nl) 1975-08-04
BE825088A (fr) 1975-07-31
IL46539A0 (en) 1975-04-25
NO750294L (US20040232935A1-20041125-M00001.png) 1975-08-25

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Legal Events

Date Code Title Description
C3 Grant after two publication steps (3rd publication)
EHJ Ceased/non-payment of the annual fee