DE2503136A1 - 5-methylthiopyrimidine, die als antidiabetische und hypocholesterinaemische arzneimittel geeignet sind - Google Patents

5-methylthiopyrimidine, die als antidiabetische und hypocholesterinaemische arzneimittel geeignet sind

Info

Publication number
DE2503136A1
DE2503136A1 DE19752503136 DE2503136A DE2503136A1 DE 2503136 A1 DE2503136 A1 DE 2503136A1 DE 19752503136 DE19752503136 DE 19752503136 DE 2503136 A DE2503136 A DE 2503136A DE 2503136 A1 DE2503136 A1 DE 2503136A1
Authority
DE
Germany
Prior art keywords
methylthiopyrimidine
formula
group
parts
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19752503136
Other languages
German (de)
English (en)
Inventor
Jean-Marie Claverie
Georges Mattioda
Rene Dr Millischer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pechiney SA
Original Assignee
Ugine Kuhlmann SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ugine Kuhlmann SA filed Critical Ugine Kuhlmann SA
Publication of DE2503136A1 publication Critical patent/DE2503136A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/56—One oxygen atom and one sulfur atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/60—Three or more oxygen or sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE19752503136 1974-01-29 1975-01-27 5-methylthiopyrimidine, die als antidiabetische und hypocholesterinaemische arzneimittel geeignet sind Withdrawn DE2503136A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7402810A FR2258841B1 (enrdf_load_stackoverflow) 1974-01-29 1974-01-29

Publications (1)

Publication Number Publication Date
DE2503136A1 true DE2503136A1 (de) 1975-07-31

Family

ID=9134107

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19752503136 Withdrawn DE2503136A1 (de) 1974-01-29 1975-01-27 5-methylthiopyrimidine, die als antidiabetische und hypocholesterinaemische arzneimittel geeignet sind

Country Status (6)

Country Link
BE (1) BE824885A (enrdf_load_stackoverflow)
DE (1) DE2503136A1 (enrdf_load_stackoverflow)
FR (1) FR2258841B1 (enrdf_load_stackoverflow)
GB (1) GB1495665A (enrdf_load_stackoverflow)
LU (1) LU71739A1 (enrdf_load_stackoverflow)
NL (1) NL7500613A (enrdf_load_stackoverflow)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999032117A1 (en) * 1997-12-22 1999-07-01 Sibia Neurosciences, Inc. Novel substituted pyridine compounds useful as modulators of acetylcholine receptors
US7470699B2 (en) 2003-07-11 2008-12-30 Arena Pharmaceuticals, Inc. Trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto
US7812159B2 (en) 2005-01-10 2010-10-12 Arena Pharamaceuticals, Inc. Processes for preparing aromatic ethers
US8293751B2 (en) 2003-01-14 2012-10-23 Arena Pharmaceuticals, Inc. 1,2,3-trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto such as diabetes and hyperglycemia
US8362248B2 (en) 2005-01-10 2013-01-29 Arena Pharmaceuticals, Inc. Substituted pyridinyl and pyrimidinyl derivatives as modulators of metabolism and the treatment of disorders related thereto
US10894787B2 (en) 2010-09-22 2021-01-19 Arena Pharmaceuticals, Inc. Modulators of the GPR119 receptor and the treatment of disorders related thereto
US11007175B2 (en) 2015-01-06 2021-05-18 Arena Pharmaceuticals, Inc. Methods of treating conditions related to the S1P1 receptor
US11534424B2 (en) 2017-02-16 2022-12-27 Arena Pharmaceuticals, Inc. Compounds and methods for treatment of primary biliary cholangitis
US11884626B2 (en) 2015-06-22 2024-01-30 Arena Pharmaceuticals, Inc. Crystalline L-arginine salt of (R)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclo-penta [b]indol-3-yl)acetic acid(Compound1) for use in S1P1 receptor-associated disorders
US12156866B2 (en) 2018-06-06 2024-12-03 Arena Pharmaceuticals, Inc. Methods of treating conditions related to the S1P1 receptor

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6632823B1 (en) 1997-12-22 2003-10-14 Merck & Co., Inc. Substituted pyridine compounds useful as modulators of acetylcholine receptors
WO1999032117A1 (en) * 1997-12-22 1999-07-01 Sibia Neurosciences, Inc. Novel substituted pyridine compounds useful as modulators of acetylcholine receptors
US8933083B2 (en) 2003-01-14 2015-01-13 Arena Pharmaceuticals, Inc. 1,2,3-trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto such as diabetes and hyperglycemia
US8293751B2 (en) 2003-01-14 2012-10-23 Arena Pharmaceuticals, Inc. 1,2,3-trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto such as diabetes and hyperglycemia
US8546429B2 (en) 2003-07-11 2013-10-01 Arena Pharmaceuticals, Inc. 1,2,3-trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto
US7470699B2 (en) 2003-07-11 2008-12-30 Arena Pharmaceuticals, Inc. Trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto
US7838525B2 (en) 2003-07-11 2010-11-23 Arena Pharmaceuticals, Inc. Trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto
US8362248B2 (en) 2005-01-10 2013-01-29 Arena Pharmaceuticals, Inc. Substituted pyridinyl and pyrimidinyl derivatives as modulators of metabolism and the treatment of disorders related thereto
US7812159B2 (en) 2005-01-10 2010-10-12 Arena Pharamaceuticals, Inc. Processes for preparing aromatic ethers
US10894787B2 (en) 2010-09-22 2021-01-19 Arena Pharmaceuticals, Inc. Modulators of the GPR119 receptor and the treatment of disorders related thereto
US11007175B2 (en) 2015-01-06 2021-05-18 Arena Pharmaceuticals, Inc. Methods of treating conditions related to the S1P1 receptor
US11884626B2 (en) 2015-06-22 2024-01-30 Arena Pharmaceuticals, Inc. Crystalline L-arginine salt of (R)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclo-penta [b]indol-3-yl)acetic acid(Compound1) for use in S1P1 receptor-associated disorders
US11534424B2 (en) 2017-02-16 2022-12-27 Arena Pharmaceuticals, Inc. Compounds and methods for treatment of primary biliary cholangitis
US12156866B2 (en) 2018-06-06 2024-12-03 Arena Pharmaceuticals, Inc. Methods of treating conditions related to the S1P1 receptor

Also Published As

Publication number Publication date
FR2258841A1 (enrdf_load_stackoverflow) 1975-08-22
NL7500613A (nl) 1975-07-31
LU71739A1 (enrdf_load_stackoverflow) 1975-06-24
FR2258841B1 (enrdf_load_stackoverflow) 1977-11-04
BE824885A (fr) 1975-07-28
GB1495665A (en) 1977-12-21

Similar Documents

Publication Publication Date Title
DE3008056C2 (enrdf_load_stackoverflow)
DE2065636A1 (de) Neue tricyclische verbindungen
DE2503136A1 (de) 5-methylthiopyrimidine, die als antidiabetische und hypocholesterinaemische arzneimittel geeignet sind
DE2631885C2 (de) 1-(4-Phenoxyphenyl)-piperazin-Derivate, ihre Salze, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Zubereitungen
DE2720545C3 (de) Derivate des 2,4-Diamino-6,7-dimethoxychinazolins, ihre Herstellung und pharmazeutische Mittel
CH544066A (de) Verfahren zur Herstellung von Fluorenverbindungen
DE2128375C3 (de) Basische substituierte Alkylidenamino-oxyalkyl-carbonsäureester, deren Säureadditionssalze, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Präparate
DE1695111B1 (de) Indolderivate
DE68912263T2 (de) 4-Methyl-5[2-(4-phenyl-1-piperazinyl)-ethyl]-Thiazolderivate, ihre Herstellung und Zusammenstellungen, die sie enthalten.
DE2845857C2 (de) Benzo [d] thiazolderivate, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittelzubereitungen
DE2348973A1 (de) Phenylpiperazinderivate, verfahren zu ihrer herstellung und ihre verwendung
DE3405727A1 (de) Isoxazol-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE2900288A1 (de) Aminoderivate von pyrazol eckige klammer auf 1,5-a eckige klammer zu s-triazin, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
DE2939914C2 (de) N-(1-Methyl-2-pyrrolidinylmethyl)-2,3-dimethoxy-5-methylsulfamoylbenzamid-Derivate, Verfahren zu ihrer Herstellung und Arzneimittel
DE2944293A1 (de) Alpha , alpha , alpha -trifluor- (aminoaryl)-aethanole, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
DE2800015A1 (de) Neue chromderivate, verfahren zu deren herstellung und diese enthaltende arzneimittel
DE2734270C2 (enrdf_load_stackoverflow)
DE2924880A1 (de) 2-aminooctahydroindolo eckige klammer auf 2,3-a eckige klammer zu chinolizin-verbindungen, verfahren zu deren herstellung und arzneimittel, welche diese enthalten
US4822778A (en) Membrane stabilizing phenoxy-piperidine compounds and pharmaceutical compositions employing such compounds
DE1493922A1 (de) Camarinderivate und Verfahren zu deren Herstellung
AT383806B (de) Verfahren zur herstellung neuer verbindungen von furo-(3,4-c)-pyridinderivaten und von deren salzen
DE2831457A1 (de) Benzamidinderivate, verfahren zu ihrer herstellung und sie enthaltende arzneimittelzubereitungen
DE2166662B2 (de) Dibenzothiazepinderivate, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel
DE2435248A1 (de) 1,3-diamino-2-propanole, ein verfahren zu deren herstellung und ein dieselben enthaltendes mittel
DE1770597C (de) 9 Piperazino 9,10 dihydro-9,10 athanoanthracene und Salze derselben sowie ihre Herstellung und pharma zeutische Zubereitungen

Legal Events

Date Code Title Description
OGA New person/name/address of the applicant
8141 Disposal/no request for examination