DE2501443C2 - Pharmazeutische Mittel mit einem Gehalt an mindestens einer diphenylsubstituierten Verbindung - Google Patents

Pharmazeutische Mittel mit einem Gehalt an mindestens einer diphenylsubstituierten Verbindung

Info

Publication number
DE2501443C2
DE2501443C2 DE2501443A DE2501443A DE2501443C2 DE 2501443 C2 DE2501443 C2 DE 2501443C2 DE 2501443 A DE2501443 A DE 2501443A DE 2501443 A DE2501443 A DE 2501443A DE 2501443 C2 DE2501443 C2 DE 2501443C2
Authority
DE
Germany
Prior art keywords
benzophenone
compounds
diphenyl
tetrahydroxy
chloride
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE2501443A
Other languages
German (de)
English (en)
Other versions
DE2501443A1 (de
Inventor
Jean-Maurice Dr. Paris Gazave
Georges Epernon Grenier
Alain Chartres Rancurel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoires Pharmascience SA
Original Assignee
Laboratoires Pharmascience SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoires Pharmascience SA filed Critical Laboratoires Pharmascience SA
Publication of DE2501443A1 publication Critical patent/DE2501443A1/de
Application granted granted Critical
Publication of DE2501443C2 publication Critical patent/DE2501443C2/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/075—Ethers or acetals
    • A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
    • A61K31/09—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon having two or more such linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
    • C07C37/01—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by replacing functional groups bound to a six-membered aromatic ring by hydroxy groups, e.g. by hydrolysis
    • C07C37/055—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by replacing functional groups bound to a six-membered aromatic ring by hydroxy groups, e.g. by hydrolysis the substituted group being bound to oxygen, e.g. ether group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46—Friedel-Crafts reactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/82—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups
    • C07C49/83—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE2501443A 1974-01-15 1975-01-15 Pharmazeutische Mittel mit einem Gehalt an mindestens einer diphenylsubstituierten Verbindung Expired DE2501443C2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7401228A FR2257272B1 (enExample) 1974-01-15 1974-01-15

Publications (2)

Publication Number Publication Date
DE2501443A1 DE2501443A1 (de) 1975-07-24
DE2501443C2 true DE2501443C2 (de) 1984-06-14

Family

ID=9133467

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2501443A Expired DE2501443C2 (de) 1974-01-15 1975-01-15 Pharmazeutische Mittel mit einem Gehalt an mindestens einer diphenylsubstituierten Verbindung

Country Status (7)

Country Link
US (1) US4015017A (enExample)
BE (1) BE824359A (enExample)
CA (1) CA1038763A (enExample)
DE (1) DE2501443C2 (enExample)
FR (1) FR2257272B1 (enExample)
GB (1) GB1495331A (enExample)
NL (1) NL179872C (enExample)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2377202A2 (fr) * 1977-01-12 1978-08-11 Pharmascience Lab Compositions pharmaceutiques contenant de l'hexahydroxy-2,3,4,3',4',5'-benzophenone
EP0315964B1 (en) * 1987-11-11 1993-01-07 Laboratoires Pharmascience A novel pharmaceutical composition comprising exifone and water-soluble polymer
GB9212673D0 (en) * 1992-06-15 1992-07-29 Celltech Ltd Chemical compounds
GB9222253D0 (en) * 1992-10-23 1992-12-09 Celltech Ltd Chemical compounds
US5622977A (en) * 1992-12-23 1997-04-22 Celltech Therapeutics Limited Tri-substituted (aryl or heteroaryl) derivatives and pharmaceutical compositions containing the same
GB9226830D0 (en) * 1992-12-23 1993-02-17 Celltech Ltd Chemical compounds
DE69418947T2 (de) * 1993-03-10 1999-12-23 Morinaga Milk Industry Co. Ltd., Tokio/Tokyo Stilbenderivate und analoga sowie deren anwendung
GB9304919D0 (en) * 1993-03-10 1993-04-28 Celltech Ltd Chemical compounds
GB9304920D0 (en) * 1993-03-10 1993-04-28 Celltech Ltd Chemical compounds
EP0738268B1 (en) * 1993-12-22 2004-03-03 Celltech R&D Limited Trisubstituted phenyl derivatives, processes for their preparation and their use as phosphodiesterase (type iv) inhibitors
GB9326173D0 (en) * 1993-12-22 1994-02-23 Celltech Ltd Chemical compounds and process
US5786354A (en) * 1994-06-21 1998-07-28 Celltech Therapeutics, Limited Tri-substituted phenyl derivatives and processes for their preparation
US6245774B1 (en) 1994-06-21 2001-06-12 Celltech Therapeutics Limited Tri-substituted phenyl or pyridine derivatives
GB9412573D0 (en) 1994-06-22 1994-08-10 Celltech Ltd Chemical compounds
GB9412571D0 (en) * 1994-06-22 1994-08-10 Celltech Ltd Chemical compounds
GB9412672D0 (en) * 1994-06-23 1994-08-10 Celltech Ltd Chemical compounds
US5977077A (en) * 1995-08-28 1999-11-02 Interlab Corporation Xanthone analogs for the treatment of infectious diseases
GB9523675D0 (en) 1995-11-20 1996-01-24 Celltech Therapeutics Ltd Chemical compounds
GB9526246D0 (en) * 1995-12-21 1996-02-21 Celltech Therapeutics Ltd Chemical compounds
GB9526245D0 (en) * 1995-12-21 1996-02-21 Celltech Therapeutics Ltd Chemical compounds
GB9526243D0 (en) * 1995-12-21 1996-02-21 Celltech Therapeutics Ltd Chemical compounds
GB9608435D0 (en) * 1996-04-24 1996-06-26 Celltech Therapeutics Ltd Chemical compounds
GB9619284D0 (en) * 1996-09-16 1996-10-30 Celltech Therapeutics Ltd Chemical compounds
GB9622363D0 (en) * 1996-10-28 1997-01-08 Celltech Therapeutics Ltd Chemical compounds
GB9625184D0 (en) * 1996-12-04 1997-01-22 Celltech Therapeutics Ltd Chemical compounds
JP2001507349A (ja) 1996-12-23 2001-06-05 セルテック セラピューティックス リミテッド 縮合多環式２−アミノピリミジン誘導体、それらの製造およびたんぱく質チロシンキナーゼ抑制因子としてのそれらの使用
GB9705361D0 (en) * 1997-03-14 1997-04-30 Celltech Therapeutics Ltd Chemical compounds
GB9713087D0 (en) * 1997-06-20 1997-08-27 Celltech Therapeutics Ltd Chemical compounds
GB9914258D0 (en) * 1999-06-18 1999-08-18 Celltech Therapeutics Ltd Chemical compounds
GB9924862D0 (en) * 1999-10-20 1999-12-22 Celltech Therapeutics Ltd Chemical compounds
US6613797B2 (en) 1999-12-02 2003-09-02 Interlab, Inc. Xanthone analogs for treating infectious diseases and complexation of heme and porphyrins
NZ529654A (en) * 2001-05-29 2005-12-23 Schering Ag CDK inhibiting pyrimidines, production thereof and their use as medicaments
CA2517886A1 (en) * 2003-03-05 2004-09-16 Celgene Corporation Diphenylethylene compounds and uses thereof
CN103449998A (zh) * 2013-08-26 2013-12-18 曹庸 非均相合成2,3,4,4′-四羟基二苯甲酮的方法
JP2019504827A (ja) 2015-12-17 2019-02-21 マサチューセッツ インスティテュート オブ テクノロジー ポリヒドロキシ化ベンゾフェノンの組成物及び神経変性障害の処置方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3068151A (en) * 1958-05-19 1962-12-11 Procter & Gamble Hair control composition
BE690791A (enExample) * 1966-12-07 1967-05-16
US3850988A (en) * 1971-09-07 1974-11-26 Gaf Corp Purification of benzophenones
US3862982A (en) * 1972-06-16 1975-01-28 Robins Co Inc A H 2-(Omega-substituted alkoxy) benzophenones

Also Published As

Publication number Publication date
GB1495331A (en) 1977-12-14
NL179872C (nl) 1986-12-01
DE2501443A1 (de) 1975-07-24
NL179872B (nl) 1986-07-01
BE824359A (fr) 1975-05-02
FR2257272B1 (enExample) 1978-08-25
CA1038763A (en) 1978-09-19
NL7500451A (nl) 1975-07-17
US4015017A (en) 1977-03-29
FR2257272A1 (enExample) 1975-08-08

Similar Documents

Publication Publication Date Title
DE2501443C2 (de) Pharmazeutische Mittel mit einem Gehalt an mindestens einer diphenylsubstituierten Verbindung
DE1443429C3 (de) Alpha-Phenylpropionsäure-Derivate und solche Derivate enthaltende Arzneimittel
DE2430251C2 (de) Chalconäther und diese enthaltende Arzneimittel
EP0054168A1 (de) 1,1,2-Triphenyl-but-1-en-Derivate sowie Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
DE2244324C2 (de) 3-Benzoylpropionsäuren mit dreifach substituiertem Benzylrest, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
DE1518002B2 (de) Isoflavane und Isoflavene und Verfahren zu ihrer Herstellung sowie diese enthaltende Arzneimittel
DE3877386T2 (de) Antikrebsverbindungen.
DD144763A5 (de) Verfahren zur herstellung von phenethanolaminen
DE2807623A1 (de) Pyrrolidinderivate, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
DE2164636A1 (de) Phenoxyalkylamine, verfahren zu ihrer herstellung und ihre verwendung
DE2501834C2 (de) Neue Appetitzügler
DE2260138A1 (de) Stoffwechselwirksame bisphenolalkanderivate
AT343104B (de) Verfahren zur herstellung von neuen naphthalinderivaten
DE3102769A1 (de) "bis-moranolinderivate"
DE2350148A1 (de) Thiophenderivate, verfahren zu deren herstellung und diese verbindungen enthaltende pharmazeutische zusammensetzungen
DE69023045T2 (de) Carboxamidderivate.
DE69814471T2 (de) Diol-verbindungen als zwischenverbindungen für die herstellung von antimykotischen verbindungen
DE2944293A1 (de) Alpha , alpha , alpha -trifluor- (aminoaryl)-aethanole, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
DE2237832A1 (de) Verfahren zur herstellung von 4hydroxymethyl-1-keto-1,2-dihydrophthalazin
DE3121175A1 (de) Erythro-1,2,3-triphenyl-1-pentanon-derivate sowie verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE2351292C3 (de) 2,10-Dichlor-6-äthoxycarbonyl-12-methyl-12H-dibenzo[d,g][1,3]dioxocin und Verfahren zu dessen Herstellung sowie diese Verbindung enthaltende Arzneimittel
DE2354931C2 (de) trans-2-Phenylbicyclooctan-Verbindungen, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Zubereitungen
DE2640884A1 (de) Neue entzuendungshemmende l-oxo-isoindolin-derivate und verfahren zu ihrer herstellung
DE2235406B2 (de) 2-Amino-4H-pyrane, Verfahren zu ihrer Herstellung sowie diese Verbindungen enthaltende Arzneimittel
DE3101093A1 (de) 1-phenyl-4-morpholino-but-1-en-3-ol-derivate, verfahren zu ihrer herstellung und sie enthaltende arzneimittel

Legal Events

Date Code Title Description
OD Request for examination
8128 New person/name/address of the agent

Representative=s name: BARTELS, H. HELD, M., DIPL.-ING. DR.-ING., PAT.-AN

D2 Grant after examination
8364 No opposition during term of opposition