DE2457971A1 - Verfahren zur herstellung von 2-acyl4-oxo-pyrazino-isochinolin-derivaten - Google Patents

Verfahren zur herstellung von 2-acyl4-oxo-pyrazino-isochinolin-derivaten

Info

Publication number
DE2457971A1
DE2457971A1 DE19742457971 DE2457971A DE2457971A1 DE 2457971 A1 DE2457971 A1 DE 2457971A1 DE 19742457971 DE19742457971 DE 19742457971 DE 2457971 A DE2457971 A DE 2457971A DE 2457971 A1 DE2457971 A1 DE 2457971A1
Authority
DE
Germany
Prior art keywords
hpi
formula
compounds
radical
carbon atoms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19742457971
Other languages
German (de)
English (en)
Inventor
Juergen Dr Seubert
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Priority to DE19742457971 priority Critical patent/DE2457971A1/de
Priority to FI753416A priority patent/FI753416A7/fi
Priority to NL7514218A priority patent/NL7514218A/xx
Priority to SE7513739A priority patent/SE7513739L/xx
Priority to AT927775A priority patent/AT356109B/de
Priority to CH1588175A priority patent/CH621787A5/de
Priority to DK552675A priority patent/DK552675A/da
Priority to JP50146810A priority patent/JPS5182298A/ja
Publication of DE2457971A1 publication Critical patent/DE2457971A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE19742457971 1974-12-07 1974-12-07 Verfahren zur herstellung von 2-acyl4-oxo-pyrazino-isochinolin-derivaten Withdrawn DE2457971A1 (de)

Priority Applications (8)

Application Number Priority Date Filing Date Title
DE19742457971 DE2457971A1 (de) 1974-12-07 1974-12-07 Verfahren zur herstellung von 2-acyl4-oxo-pyrazino-isochinolin-derivaten
FI753416A FI753416A7 (enExample) 1974-12-07 1975-12-04
NL7514218A NL7514218A (nl) 1974-12-07 1975-12-05 Werkwijze voor het bereiden van 2-acyl-4-oxo-py- razino-isochinolinederivaten.
SE7513739A SE7513739L (sv) 1974-12-07 1975-12-05 Forfarande for framstellning av 2-scyl-4-oxo-pyrazino-isokonolin-derivat
AT927775A AT356109B (de) 1974-12-07 1975-12-05 Verfahren zur herstellung von neuen 2-acyl-4- -oxo-1,2,3,6,7,11b-hexahydro-4h-pyrazino(2,1-a) isochinolin-derivaten, ihre optischen anti- poden, physiologisch unbedenklichen saeure- additionssalzen und quartaeren ammoniumsalzen
CH1588175A CH621787A5 (en) 1974-12-07 1975-12-05 Process for the preparation of 4-acyl-2-oxohexahydro-4H-pyrazinoisoquinoline derivatives
DK552675A DK552675A (da) 1974-12-07 1975-12-05 Fremgangsmade til fremstilling af 2-acyl-4-oxopyrazinoisoquinolinderivater
JP50146810A JPS5182298A (en) 1974-12-07 1975-12-08 22 ashiru 44 okiso pirajino isokinorinjudotainoseizohoho

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19742457971 DE2457971A1 (de) 1974-12-07 1974-12-07 Verfahren zur herstellung von 2-acyl4-oxo-pyrazino-isochinolin-derivaten

Publications (1)

Publication Number Publication Date
DE2457971A1 true DE2457971A1 (de) 1976-06-10

Family

ID=5932835

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19742457971 Withdrawn DE2457971A1 (de) 1974-12-07 1974-12-07 Verfahren zur herstellung von 2-acyl4-oxo-pyrazino-isochinolin-derivaten

Country Status (8)

Country Link
JP (1) JPS5182298A (enExample)
AT (1) AT356109B (enExample)
CH (1) CH621787A5 (enExample)
DE (1) DE2457971A1 (enExample)
DK (1) DK552675A (enExample)
FI (1) FI753416A7 (enExample)
NL (1) NL7514218A (enExample)
SE (1) SE7513739L (enExample)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4195984A (en) * 1979-03-12 1980-04-01 Abbott Laboratories Herbicides derived from dihalo isonicotinoyl derivatives of amino acids
US4217452A (en) * 1974-02-09 1980-08-12 Akzona Incorporated Synthesis for the preparation of tetracyclic compounds
US4254031A (en) * 1974-02-09 1981-03-03 Akzona Incorporated Synthesis for the preparation of tetracyclic compounds
FR2520740A1 (fr) * 1982-01-29 1983-08-05 Sanofi Sa Procede pour la preparation d'acyl-2-hexahydro-1,3,4,6,7,11b-2h-pyrazino (2,1-a) isoquinoleinones-4 et intermediaires
FR2533925A1 (fr) * 1982-09-30 1984-04-06 Sanofi Sa Hexahydro-1,2,3,6,7,10b thieno (3',2' : 3,4) pyrido (1,2-a) pyrazinones-4, et leur procede de preparation ainsi que leur activite anthelmintique
US4497952A (en) * 1982-07-08 1985-02-05 Korea Advanced Institute Of Science And Technology Process for the production of (±)-4-oxo-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinoline derivatives

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8563554B2 (en) 2009-03-17 2013-10-22 Concert Pharmaceuticals, Inc. Deuterated pyrazinoisoquinoline compounds

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4217452A (en) * 1974-02-09 1980-08-12 Akzona Incorporated Synthesis for the preparation of tetracyclic compounds
US4254031A (en) * 1974-02-09 1981-03-03 Akzona Incorporated Synthesis for the preparation of tetracyclic compounds
US4195984A (en) * 1979-03-12 1980-04-01 Abbott Laboratories Herbicides derived from dihalo isonicotinoyl derivatives of amino acids
FR2520740A1 (fr) * 1982-01-29 1983-08-05 Sanofi Sa Procede pour la preparation d'acyl-2-hexahydro-1,3,4,6,7,11b-2h-pyrazino (2,1-a) isoquinoleinones-4 et intermediaires
EP0086678A1 (fr) * 1982-01-29 1983-08-24 Elf Sanofi Procédé pour la préparation d'acyl-2 hexahydro-1,3,4,6,7,11b-2H-pyrazino (2,1-a)isoquinoléinones-4 et intermédiaires
US4497952A (en) * 1982-07-08 1985-02-05 Korea Advanced Institute Of Science And Technology Process for the production of (±)-4-oxo-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinoline derivatives
FR2533925A1 (fr) * 1982-09-30 1984-04-06 Sanofi Sa Hexahydro-1,2,3,6,7,10b thieno (3',2' : 3,4) pyrido (1,2-a) pyrazinones-4, et leur procede de preparation ainsi que leur activite anthelmintique

Also Published As

Publication number Publication date
NL7514218A (nl) 1976-06-09
FI753416A7 (enExample) 1976-06-08
CH621787A5 (en) 1981-02-27
ATA927775A (de) 1979-09-15
DK552675A (da) 1976-06-08
SE7513739L (sv) 1976-06-08
AT356109B (de) 1980-04-10
JPS5182298A (en) 1976-07-19

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Legal Events

Date Code Title Description
8141 Disposal/no request for examination