DE2408227A1 - Neue antibiotika und verfahren zu ihrer gewinnung - Google Patents

Neue antibiotika und verfahren zu ihrer gewinnung

Info

Publication number
DE2408227A1
DE2408227A1 DE19742408227 DE2408227A DE2408227A1 DE 2408227 A1 DE2408227 A1 DE 2408227A1 DE 19742408227 DE19742408227 DE 19742408227 DE 2408227 A DE2408227 A DE 2408227A DE 2408227 A1 DE2408227 A1 DE 2408227A1
Authority
DE
Germany
Prior art keywords
antibiotic
formula
antibiotics
derivatives
garamin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19742408227
Other languages
German (de)
English (en)
Inventor
Alan K Mallams
Richard W Tkach
Gerald H Wagman
Marvin J Weinstein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MSD International Holdings GmbH
Original Assignee
Scherico Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scherico Ltd filed Critical Scherico Ltd
Publication of DE2408227A1 publication Critical patent/DE2408227A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/224—Cyclohexane rings substituted by at least two nitrogen atoms with only one saccharide radical directly attached to the cyclohexyl radical, e.g. destomycin, fortimicin, neamine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/863—Mycobacterium

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
DE19742408227 1973-02-23 1974-02-21 Neue antibiotika und verfahren zu ihrer gewinnung Withdrawn DE2408227A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US335185A US3880828A (en) 1973-02-23 1973-02-23 Antibiotics 66-40B and 66-40D from micromonospora inyoensis

Publications (1)

Publication Number Publication Date
DE2408227A1 true DE2408227A1 (de) 1974-08-29

Family

ID=23310657

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19742408227 Withdrawn DE2408227A1 (de) 1973-02-23 1974-02-21 Neue antibiotika und verfahren zu ihrer gewinnung

Country Status (6)

Country Link
US (1) US3880828A (enExample)
BE (1) BE811370A (enExample)
DE (1) DE2408227A1 (enExample)
FR (1) FR2218876B1 (enExample)
GB (1) GB1464599A (enExample)
ZA (1) ZA741149B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014145713A3 (en) * 2013-03-15 2014-11-06 The Board Of Trustees Of The Leland Stanford Junior University Aminoglycoside antibiotics with reduced ototoxicity

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3956068A (en) * 1972-07-14 1976-05-11 Schering Corporation Antibiotic G-52 and method for the production thereof
US3988316A (en) * 1973-12-19 1976-10-26 Schering Corporation Antibiotics sisomicin and verdamicin I and complex containing same
US4009328A (en) * 1975-05-02 1977-02-22 Schering Corporation Aminoglycoside 66-40C, method for its manufacture, method for its use as an intermediate in the preparation of known antibiotics and novel antibacterials
US3978214A (en) * 1975-05-02 1976-08-31 Schering Corporation Novel 4,6-di-o-(aminoglycosyl)-2-deoxystreptamine, method for its manufacture, method for its use as an antiprotozoal agent and compositions useful thereof
US4223022A (en) 1978-01-16 1980-09-16 Schering Corporation Stabilized aminoglycoside antibiotic formulations
FR2452932A1 (fr) * 1979-04-04 1980-10-31 Toyo Jozo Kk Nouveaux antibiotiques aminoglycosides et leur production
JPS5629598A (en) * 1979-08-18 1981-03-24 Toyo Jozo Co Ltd Novel amino sugar antibiotic g-367-2 and its preparation
WO2005080340A1 (en) * 2004-02-18 2005-09-01 Metabolex, Inc. Alpha-(trifluoromethyl-substituted aryloxy, arylamino, arylthio or arylmethyl)-trifluoromethyl-substituted phenylacetic acids and derivatives as antidiabetic agents

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3651042A (en) * 1968-12-24 1972-03-21 Schering Corp Separation of the components of the gentamicin complex
JPS507595B1 (enExample) * 1970-07-29 1975-03-27

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014145713A3 (en) * 2013-03-15 2014-11-06 The Board Of Trustees Of The Leland Stanford Junior University Aminoglycoside antibiotics with reduced ototoxicity
US9238670B2 (en) 2013-03-15 2016-01-19 The Board Of Trustees Of The Leland Stanford Junior University Aminoglycoside antibiotics with reduced ototoxicity

Also Published As

Publication number Publication date
FR2218876B1 (enExample) 1977-01-28
GB1464599A (en) 1977-02-16
BE811370A (fr) 1974-06-17
US3880828A (en) 1975-04-29
AU6584674A (en) 1975-08-21
FR2218876A1 (enExample) 1974-09-20
ZA741149B (en) 1975-01-29

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Legal Events

Date Code Title Description
8139 Disposal/non-payment of the annual fee