DE2347220C3 - L-Cystin-bis-[2,2-bis-(2-chloräthyl)-hydrazid] -dihydrobromid, Verfahren zu seiner Herstellung und dieses enthaltende Arzneimittel - Google Patents

L-Cystin-bis-[2,2-bis-(2-chloräthyl)-hydrazid] -dihydrobromid, Verfahren zu seiner Herstellung und dieses enthaltende Arzneimittel

Info

Publication number
DE2347220C3
DE2347220C3 DE2347220A DE2347220A DE2347220C3 DE 2347220 C3 DE2347220 C3 DE 2347220C3 DE 2347220 A DE2347220 A DE 2347220A DE 2347220 A DE2347220 A DE 2347220A DE 2347220 C3 DE2347220 C3 DE 2347220C3
Authority
DE
Germany
Prior art keywords
bis
chloroethyl
cystine
hydrazide
percent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE2347220A
Other languages
German (de)
English (en)
Other versions
DE2347220A1 (de
DE2347220B2 (de
Inventor
Boris Vassilev Dipl.-Ing. Alexiev
Emanuil Alexandrov Dr.Med.Vet. Emanuilov
Evgeni Viktorov Dipl.-Chem. Golovinski
Liljana Stoilova Dr.Med. Maneva
Alexander Vassilev Prof. Spassov
Stoitscho Borissov Dipl.-Ing. Stoev
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
INSTITUT PO BIOCHIMIA PRI BAN SOFIA
Original Assignee
INSTITUT PO BIOCHIMIA PRI BAN SOFIA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by INSTITUT PO BIOCHIMIA PRI BAN SOFIA filed Critical INSTITUT PO BIOCHIMIA PRI BAN SOFIA
Publication of DE2347220A1 publication Critical patent/DE2347220A1/de
Publication of DE2347220B2 publication Critical patent/DE2347220B2/de
Application granted granted Critical
Publication of DE2347220C3 publication Critical patent/DE2347220C3/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • C07C243/24—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids
    • C07C243/26—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C243/34—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of a carbon skeleton further substituted by nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE2347220A 1972-09-26 1973-09-19 L-Cystin-bis-[2,2-bis-(2-chloräthyl)-hydrazid] -dihydrobromid, Verfahren zu seiner Herstellung und dieses enthaltende Arzneimittel Expired DE2347220C3 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BG21479A BG17877A1 (US20100223739A1-20100909-C00025.png) 1972-09-26 1972-09-26

Publications (3)

Publication Number Publication Date
DE2347220A1 DE2347220A1 (de) 1974-04-25
DE2347220B2 DE2347220B2 (de) 1977-10-20
DE2347220C3 true DE2347220C3 (de) 1978-06-08

Family

ID=3898847

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2347220A Expired DE2347220C3 (de) 1972-09-26 1973-09-19 L-Cystin-bis-[2,2-bis-(2-chloräthyl)-hydrazid] -dihydrobromid, Verfahren zu seiner Herstellung und dieses enthaltende Arzneimittel

Country Status (9)

Country Link
US (1) US3897494A (US20100223739A1-20100909-C00025.png)
JP (1) JPS5617342B2 (US20100223739A1-20100909-C00025.png)
BG (1) BG17877A1 (US20100223739A1-20100909-C00025.png)
CH (1) CH609677A5 (US20100223739A1-20100909-C00025.png)
DD (1) DD110035A5 (US20100223739A1-20100909-C00025.png)
DE (1) DE2347220C3 (US20100223739A1-20100909-C00025.png)
GB (1) GB1381833A (US20100223739A1-20100909-C00025.png)
HU (1) HU170709B (US20100223739A1-20100909-C00025.png)
SU (1) SU983125A1 (US20100223739A1-20100909-C00025.png)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4198433A (en) * 1976-02-02 1980-04-15 Ecnpk Po Biologia I Mediko-Biologichni Problemi Pri Ban Anti-transplanted tumor remedy
US5508272A (en) * 1993-06-15 1996-04-16 Bristol-Myers Squibb Company Compounds containing a fused bicycle ring and processes therefor
US5700831A (en) * 1996-03-12 1997-12-23 Uniroyal Chemical Company, Inc. Pesticidal hydrazide derivatives

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1140942B (de) * 1960-10-29 1962-12-13 Hoechst Ag Verfahren zur Herstellung von Bis-(ª‰-carbhydrazidoaethyl)-sulfon
GB955856A (en) * 1961-08-01 1964-04-22 Ici Ltd Hydrazine derivatives

Also Published As

Publication number Publication date
GB1381833A (en) 1975-01-29
DE2347220A1 (de) 1974-04-25
SU983125A1 (ru) 1982-12-23
DD110035A5 (US20100223739A1-20100909-C00025.png) 1974-12-05
DE2347220B2 (de) 1977-10-20
JPS5617342B2 (US20100223739A1-20100909-C00025.png) 1981-04-22
US3897494A (en) 1975-07-29
HU170709B (US20100223739A1-20100909-C00025.png) 1977-08-28
CH609677A5 (US20100223739A1-20100909-C00025.png) 1979-03-15
BG17877A1 (US20100223739A1-20100909-C00025.png) 1974-03-05
JPS5040523A (US20100223739A1-20100909-C00025.png) 1975-04-14

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Legal Events

Date Code Title Description
C3 Grant after two publication steps (3rd publication)
8328 Change in the person/name/address of the agent

Free format text: VON FUENER, A., DIPL.-CHEM. DR.RER.NAT. EBBINGHAUS, D., DIPL.-ING., PAT.-ANW., 8000 MUENCHEN

8339 Ceased/non-payment of the annual fee