DE2335750C3 - D-6-Methylergolin-derivate, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel - Google Patents

D-6-Methylergolin-derivate, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel

Info

Publication number
DE2335750C3
DE2335750C3 DE2335750A DE2335750A DE2335750C3 DE 2335750 C3 DE2335750 C3 DE 2335750C3 DE 2335750 A DE2335750 A DE 2335750A DE 2335750 A DE2335750 A DE 2335750A DE 2335750 C3 DE2335750 C3 DE 2335750C3
Authority
DE
Germany
Prior art keywords
methyl
chloroform
methylergoline
derivatives
solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE2335750A
Other languages
German (de)
English (en)
Other versions
DE2335750B2 (de
DE2335750A1 (de
Inventor
Nicholas James Bach
James Allen Clemens
Edmund Carl Kornfeld
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of DE2335750A1 publication Critical patent/DE2335750A1/de
Publication of DE2335750B2 publication Critical patent/DE2335750B2/de
Application granted granted Critical
Publication of DE2335750C3 publication Critical patent/DE2335750C3/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE2335750A 1972-07-21 1973-07-13 D-6-Methylergolin-derivate, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel Expired DE2335750C3 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US27390272A 1972-07-21 1972-07-21

Publications (3)

Publication Number Publication Date
DE2335750A1 DE2335750A1 (de) 1974-02-14
DE2335750B2 DE2335750B2 (de) 1978-02-23
DE2335750C3 true DE2335750C3 (de) 1978-10-19

Family

ID=23045910

Family Applications (2)

Application Number Title Priority Date Filing Date
DE2365974A Withdrawn DE2365974A1 (de) 1972-07-21 1973-07-13 D-6-methyl-8-mesyloxymethylergolin und verfahren zu seiner herstellung
DE2335750A Expired DE2335750C3 (de) 1972-07-21 1973-07-13 D-6-Methylergolin-derivate, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE2365974A Withdrawn DE2365974A1 (de) 1972-07-21 1973-07-13 D-6-methyl-8-mesyloxymethylergolin und verfahren zu seiner herstellung

Country Status (24)

Country Link
JP (2) JPS576431B2 (xx)
AR (3) AR206772A1 (xx)
AT (1) AT331425B (xx)
BE (1) BE802531A (xx)
BG (3) BG21410A3 (xx)
CA (1) CA1006159A (xx)
CH (5) CH578564A5 (xx)
CS (1) CS208164B2 (xx)
DD (1) DD107690A5 (xx)
DE (2) DE2365974A1 (xx)
DK (1) DK140986B (xx)
ES (5) ES417078A1 (xx)
FR (1) FR2193606B1 (xx)
GB (1) GB1423065A (xx)
HU (1) HU167274B (xx)
IE (1) IE37936B1 (xx)
IL (3) IL42730A (xx)
NL (1) NL7309969A (xx)
PH (1) PH11229A (xx)
RO (2) RO63792A (xx)
SE (3) SE393111B (xx)
SU (3) SU645581A3 (xx)
YU (1) YU36953B (xx)
ZA (1) ZA734627B (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1517973A (en) * 1974-07-19 1978-07-19 Sandoz Ltd 6-methyl-8alpha-n,n-dimethylsulphamoylaminoergoline i
US3968111A (en) * 1974-12-06 1976-07-06 Eli Lilly And Company 8,8-Disubstituted-6-methylergolines and related compounds
US4166182A (en) * 1978-02-08 1979-08-28 Eli Lilly And Company 6-n-propyl-8-methoxymethyl or methylmercaptomethylergolines and related compounds
AU526764B2 (en) * 1978-09-08 1983-01-27 Farmitalia Carlo Erba S.P.A. Ergoline derivatives
DE3587860D1 (de) * 1984-04-09 1994-07-28 Schering Ag 2-substituierte Ergolin-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel.
HU196598B (en) * 1986-04-25 1988-12-28 Richter Gedeon Vegyeszet Process for producing 1- and/or 8-substituted 2-halogenated ergoline derivatives and pharmaceutics comprising such compounds
DE3620293A1 (de) * 1986-06-16 1987-12-17 Schering Ag 1-und/oder 2-substituierte ergolinderivate
JPH0596382U (ja) * 1992-05-28 1993-12-27 イビデン株式会社 ドアユニット

Also Published As

Publication number Publication date
JPS4985099A (xx) 1974-08-15
IE37936L (en) 1974-01-21
FR2193606A1 (xx) 1974-02-22
FR2193606B1 (xx) 1977-07-15
IL48288A (en) 1976-06-30
AU5792673A (en) 1975-01-16
SU645581A3 (ru) 1979-01-30
IE37936B1 (en) 1977-11-23
CH580626A5 (xx) 1976-10-15
RO71305A (ro) 1982-03-24
DE2335750B2 (de) 1978-02-23
SU584780A3 (ru) 1977-12-15
NL7309969A (xx) 1974-01-23
YU36953B (en) 1984-08-31
ES442885A1 (es) 1977-04-16
CH578564A5 (xx) 1976-08-13
DE2335750A1 (de) 1974-02-14
SE7611467L (sv) 1976-10-15
DK140986B (da) 1979-12-17
GB1423065A (en) 1976-01-28
ES446789A1 (es) 1977-06-01
ZA734627B (en) 1974-06-26
AR206772A1 (es) 1976-08-23
DD107690A5 (xx) 1974-08-12
YU194573A (en) 1982-06-18
DE2365974A1 (de) 1977-03-24
JPS5813541B2 (ja) 1983-03-14
SE393111B (sv) 1977-05-02
DK140986C (xx) 1980-07-21
BG21410A3 (xx) 1976-05-20
AR210072A1 (es) 1977-06-30
JPS5781487A (en) 1982-05-21
BG21411A3 (xx) 1976-05-20
CS208164B2 (en) 1981-08-31
AR206887A1 (es) 1976-08-31
RO63792A (fr) 1978-12-15
CA1006159A (en) 1977-03-01
AT331425B (de) 1976-08-25
BE802531A (fr) 1974-01-21
SE410459B (sv) 1979-10-15
ES417078A1 (es) 1976-05-01
JPS576431B2 (xx) 1982-02-04
IL42730A (en) 1976-06-30
ES442887A1 (es) 1977-05-16
CH581135A5 (xx) 1976-10-29
SU575029A3 (ru) 1977-09-30
SE7611466L (sv) 1976-10-15
HU167274B (xx) 1975-09-27
CH578563A5 (xx) 1976-08-13
ATA643473A (de) 1975-11-15
ES442886A1 (es) 1977-04-16
SE410603B (sv) 1979-10-22
IL48288A0 (en) 1975-12-31
IL42730A0 (en) 1973-10-25
PH11229A (en) 1977-10-28
BG22400A3 (xx) 1977-02-20
CH580625A5 (xx) 1976-10-15

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Legal Events

Date Code Title Description
C3 Grant after two publication steps (3rd publication)
8328 Change in the person/name/address of the agent
8339 Ceased/non-payment of the annual fee