SU645581A3 - Способ получени -2-галоид-6- метил-8-цианометил или -2-галоид6-метил-8-карбоксамидометилэрголинов - Google Patents

Способ получени -2-галоид-6- метил-8-цианометил или -2-галоид6-метил-8-карбоксамидометилэрголинов

Info

Publication number
SU645581A3
SU645581A3 SU731948966A SU1948966A SU645581A3 SU 645581 A3 SU645581 A3 SU 645581A3 SU 731948966 A SU731948966 A SU 731948966A SU 1948966 A SU1948966 A SU 1948966A SU 645581 A3 SU645581 A3 SU 645581A3
Authority
SU
USSR - Soviet Union
Prior art keywords
methyl
cyanomethyl
halogen
ergoline
solution
Prior art date
Application number
SU731948966A
Other languages
English (en)
Russian (ru)
Inventor
Аллен Клеменс Джеймс
Карл Корнфельд Эдмунд
Джеймс Бах Николас
Original Assignee
Эли Лилли Энд Компани (Фирма)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Эли Лилли Энд Компани (Фирма) filed Critical Эли Лилли Энд Компани (Фирма)
Application granted granted Critical
Publication of SU645581A3 publication Critical patent/SU645581A3/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SU731948966A 1972-07-21 1973-07-20 Способ получени -2-галоид-6- метил-8-цианометил или -2-галоид6-метил-8-карбоксамидометилэрголинов SU645581A3 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US27390272A 1972-07-21 1972-07-21

Publications (1)

Publication Number Publication Date
SU645581A3 true SU645581A3 (ru) 1979-01-30

Family

ID=23045910

Family Applications (3)

Application Number Title Priority Date Filing Date
SU731948966A SU645581A3 (ru) 1972-07-21 1973-07-20 Способ получени -2-галоид-6- метил-8-цианометил или -2-галоид6-метил-8-карбоксамидометилэрголинов
SU7402080295A SU584780A3 (ru) 1972-07-21 1974-12-04 Способ получени д-2-замещенных-6-метил-8-цианометил8-цианометилэрголинов или их солей
SU7502098198A SU575029A3 (ru) 1972-07-21 1975-01-14 Способ получени д -2,6-диметил-8цианметилэрголина или его солей

Family Applications After (2)

Application Number Title Priority Date Filing Date
SU7402080295A SU584780A3 (ru) 1972-07-21 1974-12-04 Способ получени д-2-замещенных-6-метил-8-цианометил8-цианометилэрголинов или их солей
SU7502098198A SU575029A3 (ru) 1972-07-21 1975-01-14 Способ получени д -2,6-диметил-8цианметилэрголина или его солей

Country Status (24)

Country Link
JP (2) JPS576431B2 (xx)
AR (3) AR206772A1 (xx)
AT (1) AT331425B (xx)
BE (1) BE802531A (xx)
BG (3) BG21410A3 (xx)
CA (1) CA1006159A (xx)
CH (5) CH578564A5 (xx)
CS (1) CS208164B2 (xx)
DD (1) DD107690A5 (xx)
DE (2) DE2365974A1 (xx)
DK (1) DK140986B (xx)
ES (5) ES417078A1 (xx)
FR (1) FR2193606B1 (xx)
GB (1) GB1423065A (xx)
HU (1) HU167274B (xx)
IE (1) IE37936B1 (xx)
IL (3) IL42730A (xx)
NL (1) NL7309969A (xx)
PH (1) PH11229A (xx)
RO (2) RO63792A (xx)
SE (3) SE393111B (xx)
SU (3) SU645581A3 (xx)
YU (1) YU36953B (xx)
ZA (1) ZA734627B (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1517973A (en) * 1974-07-19 1978-07-19 Sandoz Ltd 6-methyl-8alpha-n,n-dimethylsulphamoylaminoergoline i
US3968111A (en) * 1974-12-06 1976-07-06 Eli Lilly And Company 8,8-Disubstituted-6-methylergolines and related compounds
US4166182A (en) * 1978-02-08 1979-08-28 Eli Lilly And Company 6-n-propyl-8-methoxymethyl or methylmercaptomethylergolines and related compounds
AU526764B2 (en) * 1978-09-08 1983-01-27 Farmitalia Carlo Erba S.P.A. Ergoline derivatives
DE3587860D1 (de) * 1984-04-09 1994-07-28 Schering Ag 2-substituierte Ergolin-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel.
HU196598B (en) * 1986-04-25 1988-12-28 Richter Gedeon Vegyeszet Process for producing 1- and/or 8-substituted 2-halogenated ergoline derivatives and pharmaceutics comprising such compounds
DE3620293A1 (de) * 1986-06-16 1987-12-17 Schering Ag 1-und/oder 2-substituierte ergolinderivate
JPH0596382U (ja) * 1992-05-28 1993-12-27 イビデン株式会社 ドアユニット

Also Published As

Publication number Publication date
JPS4985099A (xx) 1974-08-15
IE37936L (en) 1974-01-21
FR2193606A1 (xx) 1974-02-22
FR2193606B1 (xx) 1977-07-15
IL48288A (en) 1976-06-30
AU5792673A (en) 1975-01-16
IE37936B1 (en) 1977-11-23
CH580626A5 (xx) 1976-10-15
RO71305A (ro) 1982-03-24
DE2335750B2 (de) 1978-02-23
SU584780A3 (ru) 1977-12-15
NL7309969A (xx) 1974-01-23
YU36953B (en) 1984-08-31
ES442885A1 (es) 1977-04-16
CH578564A5 (xx) 1976-08-13
DE2335750A1 (de) 1974-02-14
SE7611467L (sv) 1976-10-15
DK140986B (da) 1979-12-17
GB1423065A (en) 1976-01-28
ES446789A1 (es) 1977-06-01
ZA734627B (en) 1974-06-26
AR206772A1 (es) 1976-08-23
DD107690A5 (xx) 1974-08-12
YU194573A (en) 1982-06-18
DE2365974A1 (de) 1977-03-24
JPS5813541B2 (ja) 1983-03-14
SE393111B (sv) 1977-05-02
DK140986C (xx) 1980-07-21
BG21410A3 (xx) 1976-05-20
AR210072A1 (es) 1977-06-30
JPS5781487A (en) 1982-05-21
BG21411A3 (xx) 1976-05-20
CS208164B2 (en) 1981-08-31
AR206887A1 (es) 1976-08-31
RO63792A (fr) 1978-12-15
CA1006159A (en) 1977-03-01
AT331425B (de) 1976-08-25
BE802531A (fr) 1974-01-21
SE410459B (sv) 1979-10-15
ES417078A1 (es) 1976-05-01
JPS576431B2 (xx) 1982-02-04
IL42730A (en) 1976-06-30
ES442887A1 (es) 1977-05-16
DE2335750C3 (de) 1978-10-19
CH581135A5 (xx) 1976-10-29
SU575029A3 (ru) 1977-09-30
SE7611466L (sv) 1976-10-15
HU167274B (xx) 1975-09-27
CH578563A5 (xx) 1976-08-13
ATA643473A (de) 1975-11-15
ES442886A1 (es) 1977-04-16
SE410603B (sv) 1979-10-22
IL48288A0 (en) 1975-12-31
IL42730A0 (en) 1973-10-25
PH11229A (en) 1977-10-28
BG22400A3 (xx) 1977-02-20
CH580625A5 (xx) 1976-10-15

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