IL42730A - D-6-methyl-2,8-disubstituted ergolines,their preparation and pharmaceutical compositions containing them - Google Patents

D-6-methyl-2,8-disubstituted ergolines,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL42730A
IL42730A IL42730A IL4273073A IL42730A IL 42730 A IL42730 A IL 42730A IL 42730 A IL42730 A IL 42730A IL 4273073 A IL4273073 A IL 4273073A IL 42730 A IL42730 A IL 42730A
Authority
IL
Israel
Prior art keywords
methyl
compound
chloroform
cyanomethylergoline
ergoline
Prior art date
Application number
IL42730A
Other languages
English (en)
Other versions
IL42730A0 (en
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of IL42730A0 publication Critical patent/IL42730A0/xx
Publication of IL42730A publication Critical patent/IL42730A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL42730A 1972-07-21 1973-07-12 D-6-methyl-2,8-disubstituted ergolines,their preparation and pharmaceutical compositions containing them IL42730A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US27390272A 1972-07-21 1972-07-21

Publications (2)

Publication Number Publication Date
IL42730A0 IL42730A0 (en) 1973-10-25
IL42730A true IL42730A (en) 1976-06-30

Family

ID=23045910

Family Applications (3)

Application Number Title Priority Date Filing Date
IL42730A IL42730A (en) 1972-07-21 1973-07-12 D-6-methyl-2,8-disubstituted ergolines,their preparation and pharmaceutical compositions containing them
IL48288A IL48288A (en) 1972-07-21 1973-07-12 D-6-methyl-8-(mesyloxymethyl)ergoline
IL48288A IL48288A0 (en) 1972-07-21 1975-10-13 A novel d-6-methyl-ergoline derivative

Family Applications After (2)

Application Number Title Priority Date Filing Date
IL48288A IL48288A (en) 1972-07-21 1973-07-12 D-6-methyl-8-(mesyloxymethyl)ergoline
IL48288A IL48288A0 (en) 1972-07-21 1975-10-13 A novel d-6-methyl-ergoline derivative

Country Status (24)

Country Link
JP (2) JPS576431B2 (xx)
AR (3) AR206772A1 (xx)
AT (1) AT331425B (xx)
BE (1) BE802531A (xx)
BG (3) BG21410A3 (xx)
CA (1) CA1006159A (xx)
CH (5) CH581135A5 (xx)
CS (1) CS208164B2 (xx)
DD (1) DD107690A5 (xx)
DE (2) DE2365974A1 (xx)
DK (1) DK140986B (xx)
ES (5) ES417078A1 (xx)
FR (1) FR2193606B1 (xx)
GB (1) GB1423065A (xx)
HU (1) HU167274B (xx)
IE (1) IE37936B1 (xx)
IL (3) IL42730A (xx)
NL (1) NL7309969A (xx)
PH (1) PH11229A (xx)
RO (2) RO71305A (xx)
SE (3) SE393111B (xx)
SU (3) SU645581A3 (xx)
YU (1) YU36953B (xx)
ZA (1) ZA734627B (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1517972A (en) * 1974-07-19 1978-07-19 Sandoz Ltd 6-methyl-8alpha-cyanomethylergoline i
US3968111A (en) * 1974-12-06 1976-07-06 Eli Lilly And Company 8,8-Disubstituted-6-methylergolines and related compounds
US4166182A (en) * 1978-02-08 1979-08-28 Eli Lilly And Company 6-n-propyl-8-methoxymethyl or methylmercaptomethylergolines and related compounds
AU526764B2 (en) * 1978-09-08 1983-01-27 Farmitalia Carlo Erba S.P.A. Ergoline derivatives
ATE107647T1 (de) * 1984-04-09 1994-07-15 Schering Ag 2-substituierte ergolin-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
HU196598B (en) * 1986-04-25 1988-12-28 Richter Gedeon Vegyeszet Process for producing 1- and/or 8-substituted 2-halogenated ergoline derivatives and pharmaceutics comprising such compounds
DE3620293A1 (de) * 1986-06-16 1987-12-17 Schering Ag 1-und/oder 2-substituierte ergolinderivate
JPH0596382U (ja) * 1992-05-28 1993-12-27 イビデン株式会社 ドアユニット

Also Published As

Publication number Publication date
SE7611467L (sv) 1976-10-15
IE37936L (en) 1974-01-21
BG21410A3 (xx) 1976-05-20
CH578563A5 (xx) 1976-08-13
FR2193606B1 (xx) 1977-07-15
YU194573A (en) 1982-06-18
CA1006159A (en) 1977-03-01
CH580626A5 (xx) 1976-10-15
AR206772A1 (es) 1976-08-23
SU645581A3 (ru) 1979-01-30
ZA734627B (en) 1974-06-26
ES442887A1 (es) 1977-05-16
AR210072A1 (es) 1977-06-30
DD107690A5 (xx) 1974-08-12
DK140986C (xx) 1980-07-21
ES442885A1 (es) 1977-04-16
HU167274B (xx) 1975-09-27
BG21411A3 (xx) 1976-05-20
AU5792673A (en) 1975-01-16
NL7309969A (xx) 1974-01-23
SE7611466L (sv) 1976-10-15
ES417078A1 (es) 1976-05-01
ATA643473A (de) 1975-11-15
IL48288A (en) 1976-06-30
IE37936B1 (en) 1977-11-23
RO63792A (fr) 1978-12-15
GB1423065A (en) 1976-01-28
IL48288A0 (en) 1975-12-31
SE410603B (sv) 1979-10-22
BE802531A (fr) 1974-01-21
CS208164B2 (en) 1981-08-31
CH578564A5 (xx) 1976-08-13
DE2335750B2 (de) 1978-02-23
AT331425B (de) 1976-08-25
CH581135A5 (xx) 1976-10-29
RO71305A (ro) 1982-03-24
CH580625A5 (xx) 1976-10-15
ES442886A1 (es) 1977-04-16
JPS5813541B2 (ja) 1983-03-14
DE2335750A1 (de) 1974-02-14
DE2335750C3 (de) 1978-10-19
SU575029A3 (ru) 1977-09-30
PH11229A (en) 1977-10-28
IL42730A0 (en) 1973-10-25
AR206887A1 (es) 1976-08-31
JPS5781487A (en) 1982-05-21
DK140986B (da) 1979-12-17
SE393111B (sv) 1977-05-02
SU584780A3 (ru) 1977-12-15
JPS4985099A (xx) 1974-08-15
BG22400A3 (xx) 1977-02-20
ES446789A1 (es) 1977-06-01
DE2365974A1 (de) 1977-03-24
JPS576431B2 (xx) 1982-02-04
YU36953B (en) 1984-08-31
SE410459B (sv) 1979-10-15
FR2193606A1 (xx) 1974-02-22

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