DE2323615C2 - - Google Patents
Info
- Publication number
- DE2323615C2 DE2323615C2 DE2323615A DE2323615A DE2323615C2 DE 2323615 C2 DE2323615 C2 DE 2323615C2 DE 2323615 A DE2323615 A DE 2323615A DE 2323615 A DE2323615 A DE 2323615A DE 2323615 C2 DE2323615 C2 DE 2323615C2
- Authority
- DE
- Germany
- Prior art keywords
- animals
- steroid
- estradiol
- triene
- compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000203 mixture Substances 0.000 claims description 24
- RJKFOVLPORLFTN-LEKSSAKUSA-N Progesterone Chemical compound C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](C(=O)C)[C@@]1(C)CC2 RJKFOVLPORLFTN-LEKSSAKUSA-N 0.000 claims description 12
- VOXZDWNPVJITMN-ZBRFXRBCSA-N 17β-estradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 VOXZDWNPVJITMN-ZBRFXRBCSA-N 0.000 claims description 10
- 229930182833 estradiol Natural products 0.000 claims description 10
- 229960005309 estradiol Drugs 0.000 claims description 8
- 230000001195 anabolic effect Effects 0.000 claims description 6
- 239000000186 progesterone Substances 0.000 claims description 5
- 229960003387 progesterone Drugs 0.000 claims description 5
- UREBDLICKHMUKA-CXSFZGCWSA-N dexamethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-CXSFZGCWSA-N 0.000 claims description 4
- 229960003957 dexamethasone Drugs 0.000 claims description 4
- -1 β- ethoxy- β- ethoxy Chemical group 0.000 claims description 4
- 239000003098 androgen Substances 0.000 claims description 3
- 230000001076 estrogenic effect Effects 0.000 claims description 3
- KNFXXAGQEUUZAZ-UHFFFAOYSA-N ethyl ethaneperoxoate Chemical compound CCOOC(C)=O KNFXXAGQEUUZAZ-UHFFFAOYSA-N 0.000 claims description 3
- 239000003263 anabolic agent Substances 0.000 claims 1
- MEHHPFQKXOUFFV-OWSLCNJRSA-N trenbolone Chemical compound C1CC(=O)C=C2CC[C@@H]([C@H]3[C@@](C)([C@H](CC3)O)C=C3)C3=C21 MEHHPFQKXOUFFV-OWSLCNJRSA-N 0.000 claims 1
- 229960000312 trenbolone Drugs 0.000 claims 1
- 241001465754 Metazoa Species 0.000 description 30
- 239000007943 implant Substances 0.000 description 17
- 150000003431 steroids Chemical class 0.000 description 12
- 229940011871 estrogen Drugs 0.000 description 10
- 239000000262 estrogen Substances 0.000 description 10
- 239000003826 tablet Substances 0.000 description 9
- 244000309466 calf Species 0.000 description 8
- 239000000126 substance Substances 0.000 description 8
- CMRJPMODSSEAPL-FYQPLNBISA-N Trenbolone acetate Chemical compound C1CC2=CC(=O)CCC2=C2[C@@H]1[C@@H]1CC[C@H](OC(=O)C)[C@@]1(C)C=C2 CMRJPMODSSEAPL-FYQPLNBISA-N 0.000 description 7
- 230000000694 effects Effects 0.000 description 7
- 230000003054 hormonal effect Effects 0.000 description 7
- 241000283690 Bos taurus Species 0.000 description 6
- 206010054949 Metaplasia Diseases 0.000 description 6
- 230000015689 metaplastic ossification Effects 0.000 description 6
- 210000002307 prostate Anatomy 0.000 description 6
- 238000010521 absorption reaction Methods 0.000 description 5
- 238000002513 implantation Methods 0.000 description 5
- 239000004480 active ingredient Substances 0.000 description 4
- 229940071886 estradiol 20 mg Drugs 0.000 description 4
- 210000003491 skin Anatomy 0.000 description 4
- 230000004584 weight gain Effects 0.000 description 4
- 235000019786 weight gain Nutrition 0.000 description 4
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 3
- 229920002472 Starch Polymers 0.000 description 3
- 238000009395 breeding Methods 0.000 description 3
- 230000001488 breeding effect Effects 0.000 description 3
- 150000001875 compounds Chemical class 0.000 description 3
- 238000009472 formulation Methods 0.000 description 3
- 231100000508 hormonal effect Toxicity 0.000 description 3
- 239000008101 lactose Substances 0.000 description 3
- 238000003307 slaughter Methods 0.000 description 3
- 229940023144 sodium glycolate Drugs 0.000 description 3
- 239000008107 starch Substances 0.000 description 3
- 235000019698 starch Nutrition 0.000 description 3
- JEJAMASKDTUEBZ-UHFFFAOYSA-N tris(1,1,3-tribromo-2,2-dimethylpropyl) phosphate Chemical compound BrCC(C)(C)C(Br)(Br)OP(=O)(OC(Br)(Br)C(C)(C)CBr)OC(Br)(Br)C(C)(C)CBr JEJAMASKDTUEBZ-UHFFFAOYSA-N 0.000 description 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- GZGZWHKGQNQJDW-UHFFFAOYSA-L C(CCCCCCCCCCCCCCCCC)(=O)[O-].[Mg+2].N1C(CCC1)=O.C(CCCCCCCCCCCCCCCCC)(=O)[O-] Chemical compound C(CCCCCCCCCCCCCCCCC)(=O)[O-].[Mg+2].N1C(CCC1)=O.C(CCCCCCCCCCCCCCCCC)(=O)[O-] GZGZWHKGQNQJDW-UHFFFAOYSA-L 0.000 description 2
- 241000282887 Suidae Species 0.000 description 2
- MUMGGOZAMZWBJJ-DYKIIFRCSA-N Testostosterone Chemical compound O=C1CC[C@]2(C)[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 MUMGGOZAMZWBJJ-DYKIIFRCSA-N 0.000 description 2
- 210000004207 dermis Anatomy 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 229940088597 hormone Drugs 0.000 description 2
- 239000005556 hormone Substances 0.000 description 2
- 230000004060 metabolic process Effects 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 2
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 2
- 239000001267 polyvinylpyrrolidone Substances 0.000 description 2
- 229940022719 progesterone 200 mg Drugs 0.000 description 2
- 239000000583 progesterone congener Substances 0.000 description 2
- 230000000384 rearing effect Effects 0.000 description 2
- MPQOWLNEPUIIBZ-SQNIBIBYSA-N (8s,13s,14s)-13-methyl-1,2,3,6,7,8,14,15,16,17-decahydrocyclopenta[a]phenanthrene Chemical compound C1CC2=CCCCC2=C2[C@@H]1[C@@H]1CCC[C@@]1(C)C=C2 MPQOWLNEPUIIBZ-SQNIBIBYSA-N 0.000 description 1
- GCKMFJBGXUYNAG-UHFFFAOYSA-N 17alpha-methyltestosterone Natural products C1CC2=CC(=O)CCC2(C)C2C1C1CCC(C)(O)C1(C)CC2 GCKMFJBGXUYNAG-UHFFFAOYSA-N 0.000 description 1
- GCKMFJBGXUYNAG-HLXURNFRSA-N Methyltestosterone Chemical compound C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@](C)(O)[C@@]1(C)CC2 GCKMFJBGXUYNAG-HLXURNFRSA-N 0.000 description 1
- 241001494479 Pecora Species 0.000 description 1
- 230000001548 androgenic effect Effects 0.000 description 1
- 229940030486 androgens Drugs 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000001217 buttock Anatomy 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- RGLYKWWBQGJZGM-ISLYRVAYSA-N diethylstilbestrol Chemical compound C=1C=C(O)C=CC=1C(/CC)=C(\CC)C1=CC=C(O)C=C1 RGLYKWWBQGJZGM-ISLYRVAYSA-N 0.000 description 1
- 229960000452 diethylstilbestrol Drugs 0.000 description 1
- 230000001079 digestive effect Effects 0.000 description 1
- 230000008034 disappearance Effects 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 210000000624 ear auricle Anatomy 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 229960001566 methyltestosterone Drugs 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 239000008188 pellet Substances 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 230000000365 steroidogenetic effect Effects 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 229960003604 testosterone Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/168—Steroids
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/184—Hormones
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Polymers & Plastics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Food Science & Technology (AREA)
- Animal Husbandry (AREA)
- Zoology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Feed For Specific Animals (AREA)
- Fodder In General (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7216665A FR2183555B1 (en, 2012) | 1972-05-10 | 1972-05-10 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE2323615A1 DE2323615A1 (de) | 1973-11-22 |
| DE2323615C2 true DE2323615C2 (en, 2012) | 1987-08-13 |
Family
ID=9098276
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE2323615A Granted DE2323615A1 (de) | 1972-05-10 | 1973-05-10 | Zootechnische zusammensetzungen |
Country Status (9)
| Country | Link |
|---|---|
| JP (1) | JPS6017770B2 (en, 2012) |
| CA (1) | CA1001072A (en, 2012) |
| DE (1) | DE2323615A1 (en, 2012) |
| DK (1) | DK156539C (en, 2012) |
| FR (1) | FR2183555B1 (en, 2012) |
| GB (1) | GB1420831A (en, 2012) |
| IE (1) | IE37621B1 (en, 2012) |
| NL (1) | NL180276C (en, 2012) |
| SU (1) | SU545244A3 (en, 2012) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2248029B1 (en, 2012) * | 1973-10-19 | 1977-03-11 | Roussel Uclaf | |
| FR2388560A1 (fr) * | 1977-04-27 | 1978-11-24 | Roussel Uclaf | Nouvelles compositions zootechniques renfermant d'une part le zeranol et d'autre part un steroide 4,9,11 trienique |
| JPS54145819A (en) * | 1978-05-04 | 1979-11-14 | Nippon Denso Co Ltd | Engine control |
| DE10305811A1 (de) | 2003-02-12 | 2004-08-26 | Ethicon Gmbh | Chirurgisches Implantat |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA889253A (en) * | 1971-12-28 | E. Jordan Charles | Method of finishing swine for market | |
| DE1047596B (de) * | 1956-12-31 | 1958-12-24 | Olin Mathieson | Hormonpraeparat zur Aufzucht und zum Maesten von Rindvieh und Schafen |
| NL126395C (en, 2012) * | 1962-03-06 | |||
| FR1380414A (fr) * | 1962-04-20 | 1964-12-04 | Roussel Uclaf | Nouveaux stéroïdes estratriènes et procédé de préparation |
| NL124139C (en, 2012) * | 1964-11-04 | |||
| FR5301M (en, 2012) * | 1966-01-21 | 1967-08-16 | ||
| CA919594A (en) * | 1966-03-02 | 1973-01-23 | C. Bachman Marvin | Composition |
| FR5519M (en, 2012) * | 1966-06-07 | 1967-11-06 |
-
1972
- 1972-05-10 FR FR7216665A patent/FR2183555B1/fr not_active Expired
-
1973
- 1973-05-08 SU SU1916394A patent/SU545244A3/ru active
- 1973-05-08 CA CA170,704A patent/CA1001072A/en not_active Expired
- 1973-05-09 NL NLAANVRAGE7306463,A patent/NL180276C/xx not_active IP Right Cessation
- 1973-05-10 DK DK257673A patent/DK156539C/da not_active IP Right Cessation
- 1973-05-10 DE DE2323615A patent/DE2323615A1/de active Granted
- 1973-05-10 JP JP48051246A patent/JPS6017770B2/ja not_active Expired
- 1973-05-10 GB GB2231873A patent/GB1420831A/en not_active Expired
- 1973-05-10 IE IE743/73A patent/IE37621B1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NL180276C (nl) | 1987-02-02 |
| GB1420831A (en) | 1976-01-14 |
| JPS6017770B2 (ja) | 1985-05-07 |
| IE37621B1 (en) | 1977-08-31 |
| CA1001072A (en) | 1976-12-07 |
| DK156539B (da) | 1989-09-11 |
| DE2323615A1 (de) | 1973-11-22 |
| AU5548273A (en) | 1974-11-14 |
| IE37621L (en) | 1973-11-10 |
| NL7306463A (en, 2012) | 1973-11-13 |
| JPS4947515A (en, 2012) | 1974-05-08 |
| FR2183555B1 (en, 2012) | 1975-06-20 |
| FR2183555A1 (en, 2012) | 1973-12-21 |
| DK156539C (da) | 1990-01-29 |
| SU545244A3 (ru) | 1977-01-30 |
| NL180276B (nl) | 1986-09-01 |
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| Lang | Die Physiologie der Vitamine | |
| DE1047596B (de) | Hormonpraeparat zur Aufzucht und zum Maesten von Rindvieh und Schafen | |
| DE3132817C2 (en, 2012) | ||
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| der verschiedenen Gestagene | H. STEINBECK |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| OD | Request for examination | ||
| 8128 | New person/name/address of the agent |
Representative=s name: ZUMSTEIN SEN., F., DR. ASSMANN, E., DIPL.-CHEM. DR |
|
| D2 | Grant after examination | ||
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |