DE2322893A1 - Prostaglandin e tief 1 -vorprodukte und verfahren zu ihrer herstellung - Google Patents

Prostaglandin e tief 1 -vorprodukte und verfahren zu ihrer herstellung

Info

Publication number
DE2322893A1
DE2322893A1 DE2322893A DE2322893A DE2322893A1 DE 2322893 A1 DE2322893 A1 DE 2322893A1 DE 2322893 A DE2322893 A DE 2322893A DE 2322893 A DE2322893 A DE 2322893A DE 2322893 A1 DE2322893 A1 DE 2322893A1
Authority
DE
Germany
Prior art keywords
oxo
hydroxy
acid
cyclic
cyclopentanheptanoic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE2322893A
Other languages
German (de)
English (en)
Inventor
David Taub
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of DE2322893A1 publication Critical patent/DE2322893A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE2322893A 1972-05-08 1973-05-07 Prostaglandin e tief 1 -vorprodukte und verfahren zu ihrer herstellung Withdrawn DE2322893A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US251726A US3890351A (en) 1972-05-08 1972-05-08 Loweralkyl esters of 3{62 -{8 tri(lower alkyl)silyloxy{9 -2{60 -(3-oxo or hydroxy-1-octenyl)-5-oxo-1{62 -cyclopentane-heptanoic acid, 5-cyclic ethylene acetal

Publications (1)

Publication Number Publication Date
DE2322893A1 true DE2322893A1 (de) 1973-11-22

Family

ID=22953147

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2322893A Withdrawn DE2322893A1 (de) 1972-05-08 1973-05-07 Prostaglandin e tief 1 -vorprodukte und verfahren zu ihrer herstellung

Country Status (5)

Country Link
US (1) US3890351A (enExample)
CH (1) CH579581A5 (enExample)
DE (1) DE2322893A1 (enExample)
FR (1) FR2189414B1 (enExample)
GB (1) GB1413566A (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4005106A (en) * 1974-01-23 1977-01-25 Merck & Co., Inc. 3β-[(Methoxalyl)oxy]-2α-(3-oxo-1-octenyl)-5-oxo-1β-cyclopentaneheptanoic acid and process
US3992412A (en) * 1974-01-23 1976-11-16 Merck & Co., Inc. 2α-(2-Carboxy-2-oxoethyl)-3β-hydroxy-5-oxo-1β-cyclopentaneheptanoic acid and process
US3991083A (en) * 1974-01-23 1976-11-09 Merck & Co., Inc. 2α-(2-Loweralkanoyloxy-2-carboxyvinyl)-3β-hydroxy-5-oxo-1β-c
US3998849A (en) * 1974-01-23 1976-12-21 Merck & Co., Inc. 2α-(2-Carboxy-2-formylethyl)-3β-hydroxy-5-oxo-β-cyclopentaneheptanoic acid and process
US3992411A (en) * 1974-01-23 1976-11-16 Merck & Co., Inc. 2α-Formyl-3β-[(methoxalyl)oxy]-5-oxo-1β-cyclopentaneheptanoic acid and process
GB1545847A (en) * 1975-04-17 1979-05-16 American Cyanamid Co Cyclic ketals of prostaglandin e analogues
US4045465A (en) * 1976-08-06 1977-08-30 Pfizer Inc. Cyanoprostaglandins
AU529883B2 (en) * 1978-09-04 1983-06-23 Australian National University, The Substituted cyclopentenones

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3736335A (en) * 1970-06-22 1973-05-29 Merck & Co Inc Prostaglandins and methods of making same

Also Published As

Publication number Publication date
CH579581A5 (enExample) 1976-09-15
FR2189414A1 (enExample) 1974-01-25
FR2189414B1 (enExample) 1977-12-30
US3890351A (en) 1975-06-17
GB1413566A (en) 1975-11-12

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