DE2128467A1 - Verfahren zur Herstellung von Codein - Google Patents

Verfahren zur Herstellung von Codein

Info

Publication number
DE2128467A1
DE2128467A1 DE19712128467 DE2128467A DE2128467A1 DE 2128467 A1 DE2128467 A1 DE 2128467A1 DE 19712128467 DE19712128467 DE 19712128467 DE 2128467 A DE2128467 A DE 2128467A DE 2128467 A1 DE2128467 A1 DE 2128467A1
Authority
DE
Germany
Prior art keywords
hydroxy
formula
methoxy
halide
isomeric compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE19712128467
Other languages
German (de)
English (en)
Inventor
David Fred Plainfield; Schoenewaldt Erwin Frederick Watchung; N.J. Hinkley (V.StA.)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of DE2128467A1 publication Critical patent/DE2128467A1/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/28—Morphinans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18—Aralkyl radicals
    • C07D217/20—Aralkyl radicals with oxygen atoms directly attached to the aromatic ring of said aralkyl radical, e.g. papaverine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE19712128467 1970-06-09 1971-06-08 Verfahren zur Herstellung von Codein Pending DE2128467A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BE90137 1970-06-09

Publications (1)

Publication Number Publication Date
DE2128467A1 true DE2128467A1 (de) 1971-12-30

Family

ID=3841365

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19712128467 Pending DE2128467A1 (de) 1970-06-09 1971-06-08 Verfahren zur Herstellung von Codein

Country Status (6)

Country Link
CA (1) CA939665A (enrdf_load_stackoverflow)
CH (1) CH560218A5 (enrdf_load_stackoverflow)
DE (1) DE2128467A1 (enrdf_load_stackoverflow)
FR (1) FR2096107A5 (enrdf_load_stackoverflow)
GB (1) GB1330581A (enrdf_load_stackoverflow)
NL (1) NL7107921A (enrdf_load_stackoverflow)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57501083A (enrdf_load_stackoverflow) * 1980-07-03 1982-06-24 Us Commerce
US4368326A (en) 1980-07-03 1983-01-11 Rice Kenner C Short total synthesis of dihydrothebainone, dihydrocodeinone, and nordihydroccodeinone
US4521601A (en) * 1981-05-20 1985-06-04 The United States Of America As Represented By The Department Of Health & Human Services Practical total synthesis unnatural enantiomers of opium-derived morphinans

Also Published As

Publication number Publication date
GB1330581A (en) 1973-09-19
FR2096107A5 (enrdf_load_stackoverflow) 1972-02-11
NL7107921A (enrdf_load_stackoverflow) 1971-12-13
CA939665A (en) 1974-01-08
CH560218A5 (enrdf_load_stackoverflow) 1975-03-27

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