DE2040580A1 - Thiazolderivate - Google Patents

Thiazolderivate

Info

Publication number
DE2040580A1
DE2040580A1 DE19702040580 DE2040580A DE2040580A1 DE 2040580 A1 DE2040580 A1 DE 2040580A1 DE 19702040580 DE19702040580 DE 19702040580 DE 2040580 A DE2040580 A DE 2040580A DE 2040580 A1 DE2040580 A1 DE 2040580A1
Authority
DE
Germany
Prior art keywords
general formula
compound
given above
solution
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE19702040580
Other languages
German (de)
English (en)
Inventor
John Dowding
Leeds William George
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
May and Baker Ltd
Original Assignee
May and Baker Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by May and Baker Ltd filed Critical May and Baker Ltd
Publication of DE2040580A1 publication Critical patent/DE2040580A1/de
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38Nitrogen atoms
    • C07D277/44Acylated amino or imino radicals
    • C07D277/46Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38Nitrogen atoms
    • C07D277/42Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38Nitrogen atoms
    • C07D277/44Acylated amino or imino radicals
    • C07D277/48Acylated amino or imino radicals by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof, e.g. carbonylguanidines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DE19702040580 1969-08-15 1970-08-14 Thiazolderivate Pending DE2040580A1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB4086869 1969-08-15
GB348870 1970-01-23

Publications (1)

Publication Number Publication Date
DE2040580A1 true DE2040580A1 (de) 1971-04-22

Family

ID=26238346

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19702040580 Pending DE2040580A1 (de) 1969-08-15 1970-08-14 Thiazolderivate

Country Status (10)

Country Link
BE (1) BE754783A (xx)
CA (1) CA932335A (xx)
CH (1) CH525611A (xx)
DD (1) DD102055A5 (xx)
DE (1) DE2040580A1 (xx)
FR (1) FR2063138A1 (xx)
IE (1) IE34465B1 (xx)
IL (1) IL35109A0 (xx)
NL (1) NL7011738A (xx)
OA (1) OA03551A (xx)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4535088A (en) * 1982-12-21 1985-08-13 Shionogi & Co., Ltd. Propynylaminothiazole derivatives
WO2000026203A1 (en) * 1998-10-30 2000-05-11 Pharmacia & Upjohn S.P.A. 2-ureido-thiazole derivatives, process for their preparation, and their use as antitumor agents
US7598391B2 (en) 2004-01-06 2009-10-06 Novo Nordisk A/S Heteroaryl-ureas and their use as glucokinase activators
US7884210B2 (en) 2005-07-14 2011-02-08 Novo Nordisk A/S Ureido-thiazole glucokinase activators
US7897628B2 (en) 2002-06-27 2011-03-01 Novo Nordisk A/S Aryl carbonyl derivatives as therapeutic agents
US7999114B2 (en) 2005-07-08 2011-08-16 Novo Nordisk A/S Dicycloalkylcarbamoyl ureas as glucokinase activators
US8138185B2 (en) 2007-01-09 2012-03-20 Novo Nordisk A/S Urea glucokinase activators
US8318778B2 (en) 2007-01-11 2012-11-27 Novo Nordisk A/S Urea glucokinase activators
US11833136B2 (en) 2018-06-12 2023-12-05 Vtv Therapeutics Llc Therapeutic uses of glucokinase activators in combination with insulin or insulin analogs

Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4535088A (en) * 1982-12-21 1985-08-13 Shionogi & Co., Ltd. Propynylaminothiazole derivatives
WO2000026203A1 (en) * 1998-10-30 2000-05-11 Pharmacia & Upjohn S.P.A. 2-ureido-thiazole derivatives, process for their preparation, and their use as antitumor agents
US8063081B2 (en) 2002-06-27 2011-11-22 Novo Nordisk A/S Aryl carbonyl derivatives as therapeutic agents
US7897628B2 (en) 2002-06-27 2011-03-01 Novo Nordisk A/S Aryl carbonyl derivatives as therapeutic agents
US7872139B2 (en) 2004-01-06 2011-01-18 Novo Nordisk A/S Heteroaryl-ureas and their use as glucokinase activators
US7851636B2 (en) 2004-01-06 2010-12-14 Novo Nordisk A/S Heteroaryl-ureas and their use as glucokinase activators
US7598391B2 (en) 2004-01-06 2009-10-06 Novo Nordisk A/S Heteroaryl-ureas and their use as glucokinase activators
US8263634B2 (en) 2004-01-06 2012-09-11 Novo Nordisk A/S Heteroaryl-ureas and their use as glucokinase activators
USRE45183E1 (en) 2004-01-06 2014-10-07 Novo Nordisk A/S Heteroaryl-ureas and their use as glucokinase activators
US7999114B2 (en) 2005-07-08 2011-08-16 Novo Nordisk A/S Dicycloalkylcarbamoyl ureas as glucokinase activators
US7884210B2 (en) 2005-07-14 2011-02-08 Novo Nordisk A/S Ureido-thiazole glucokinase activators
US8586614B2 (en) 2005-07-14 2013-11-19 Novo Nordisk A/S Urea glucokinase activators
US8138185B2 (en) 2007-01-09 2012-03-20 Novo Nordisk A/S Urea glucokinase activators
US8318778B2 (en) 2007-01-11 2012-11-27 Novo Nordisk A/S Urea glucokinase activators
US8362049B2 (en) 2007-01-11 2013-01-29 Novo Nordisk A/S Urea glucokinase activators
US11833136B2 (en) 2018-06-12 2023-12-05 Vtv Therapeutics Llc Therapeutic uses of glucokinase activators in combination with insulin or insulin analogs
US11974989B2 (en) 2018-06-12 2024-05-07 Vtv Therapeutics Llc Therapeutic uses of glucokinase activators in combination with insulin or insulin analogs

Also Published As

Publication number Publication date
BE754783A (fr) 1971-02-12
NL7011738A (xx) 1971-02-17
FR2063138B1 (xx) 1973-01-12
CA932335A (en) 1973-08-21
CH525611A (fr) 1972-07-31
IL35109A0 (en) 1970-10-30
OA03551A (fr) 1971-03-30
IE34465L (en) 1971-02-15
FR2063138A1 (en) 1971-07-09
DD102055A5 (xx) 1973-12-05
IE34465B1 (en) 1975-05-14

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