DE2021718A1 - Neue steroidale 21-AEtherderivate und Verfahren zu ihrer Herstellung - Google Patents

Neue steroidale 21-AEtherderivate und Verfahren zu ihrer Herstellung

Info

Publication number
DE2021718A1
DE2021718A1 DE19702021718 DE2021718A DE2021718A1 DE 2021718 A1 DE2021718 A1 DE 2021718A1 DE 19702021718 DE19702021718 DE 19702021718 DE 2021718 A DE2021718 A DE 2021718A DE 2021718 A1 DE2021718 A1 DE 2021718A1
Authority
DE
Germany
Prior art keywords
dione
methyl
namely
cyclopentyl
compounds according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE19702021718
Other languages
German (de)
English (en)
Inventor
Edwards John Ansley
Belig Berkoz
Cross Alexander Dennis
Fried John Hans
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Palo Alto LLC
Original Assignee
Roche Palo Alto LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Palo Alto LLC filed Critical Roche Palo Alto LLC
Publication of DE2021718A1 publication Critical patent/DE2021718A1/de
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE19702021718 1969-05-05 1970-05-04 Neue steroidale 21-AEtherderivate und Verfahren zu ihrer Herstellung Pending DE2021718A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US82204969A 1969-05-05 1969-05-05

Publications (1)

Publication Number Publication Date
DE2021718A1 true DE2021718A1 (de) 1970-11-19

Family

ID=25234977

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19702021718 Pending DE2021718A1 (de) 1969-05-05 1970-05-04 Neue steroidale 21-AEtherderivate und Verfahren zu ihrer Herstellung

Country Status (4)

Country Link
DE (1) DE2021718A1 (https=)
FR (1) FR2044764B1 (https=)
GB (1) GB1302572A (https=)
NL (1) NL7005500A (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011029547A3 (en) * 2009-09-11 2011-08-18 Chiesi Farmaceutici S.P.A. Pregnane derivatives condensed in the 16, 17 position with an n-substituted isoxazolidine ring as anti-inflammatory agents

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5446177A (en) * 1984-12-28 1995-08-29 Alcon Laboratories, Inc. Anti-inflammatory compounds for ophthalmic use
US5420120A (en) * 1993-12-17 1995-05-30 Alcon Laboratories, Inc. Anti-inflammatory glucocorticoid compounds for topical ophthalmic use

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2966486A (en) * 1959-03-20 1960-12-27 American Cyanamid Co 16alpha, 17alpha-substituted methylene dioxy ethers of steroids of the pregnane series and method of preparing the same

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011029547A3 (en) * 2009-09-11 2011-08-18 Chiesi Farmaceutici S.P.A. Pregnane derivatives condensed in the 16, 17 position with an n-substituted isoxazolidine ring as anti-inflammatory agents
JP2013504524A (ja) * 2009-09-11 2013-02-07 シエシー ファルマセウティチィ ソシエタ ペル アチオニ イソオキサゾリジン誘導体
US8637662B2 (en) 2009-09-11 2014-01-28 Chiesi Farmaceutici S.P.A. Isoxazolidine derivatives
AU2010294598B2 (en) * 2009-09-11 2016-09-01 Chiesi Farmaceutici S.P.A. Pregnane derivatives condensed in the 16, 17 position with an n-substituted isoxazolidine ring as anti-inflammatory agents
EA025191B1 (ru) * 2009-09-11 2016-11-30 КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А. Производные прегнана, конденсированные по положению 16,17 с n-замещенным изоксалидиновым кольцом, в качестве противовоспалительных агентов

Also Published As

Publication number Publication date
GB1302572A (https=) 1973-01-10
FR2044764B1 (https=) 1974-04-12
NL7005500A (https=) 1970-11-09
FR2044764A1 (https=) 1971-02-26

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