DE2013040A1 - Arzneimitteltablette zur oralen Verabreichung - Google Patents
Arzneimitteltablette zur oralen VerabreichungInfo
- Publication number
- DE2013040A1 DE2013040A1 DE19702013040 DE2013040A DE2013040A1 DE 2013040 A1 DE2013040 A1 DE 2013040A1 DE 19702013040 DE19702013040 DE 19702013040 DE 2013040 A DE2013040 A DE 2013040A DE 2013040 A1 DE2013040 A1 DE 2013040A1
- Authority
- DE
- Germany
- Prior art keywords
- tablet according
- tablet
- acidic compound
- pharmacologically active
- carbo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000007513 acids Chemical class 0.000 claims description 12
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 claims description 8
- -1 amino-substituted carboxylic acid Chemical class 0.000 claims description 7
- 150000003839 salts Chemical class 0.000 claims description 7
- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 claims description 6
- 239000004471 Glycine Substances 0.000 claims description 4
- 229940056360 penicillin g Drugs 0.000 claims description 4
- 235000019371 penicillin G benzathine Nutrition 0.000 claims description 3
- 239000004094 surface-active agent Substances 0.000 claims description 3
- 241000845082 Panama Species 0.000 claims description 2
- 150000008051 alkyl sulfates Chemical class 0.000 claims description 2
- 125000000129 anionic group Chemical group 0.000 claims description 2
- 210000001072 colon Anatomy 0.000 claims description 2
- 150000001875 compounds Chemical class 0.000 description 10
- 239000008280 blood Substances 0.000 description 7
- 210000004369 blood Anatomy 0.000 description 7
- 239000006185 dispersion Substances 0.000 description 7
- 239000000203 mixture Substances 0.000 description 7
- 239000002775 capsule Substances 0.000 description 4
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 description 4
- 229930182555 Penicillin Natural products 0.000 description 3
- 150000002960 penicillins Chemical class 0.000 description 3
- 159000000000 sodium salts Chemical class 0.000 description 3
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 238000009472 formulation Methods 0.000 description 2
- 230000002496 gastric effect Effects 0.000 description 2
- 235000019359 magnesium stearate Nutrition 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000000546 pharmaceutical excipient Substances 0.000 description 2
- 235000019333 sodium laurylsulphate Nutrition 0.000 description 2
- 229930186147 Cephalosporin Natural products 0.000 description 1
- WHUUTDBJXJRKMK-UHFFFAOYSA-N Glutamic acid Natural products OC(=O)C(N)CCC(O)=O WHUUTDBJXJRKMK-UHFFFAOYSA-N 0.000 description 1
- QIVBCDIJIAJPQS-VIFPVBQESA-N L-tryptophane Chemical compound C1=CC=C2C(C[C@H](N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-VIFPVBQESA-N 0.000 description 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 1
- 239000004472 Lysine Substances 0.000 description 1
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 description 1
- 239000004141 Sodium laurylsulphate Substances 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- QIVBCDIJIAJPQS-UHFFFAOYSA-N Tryptophan Natural products C1=CC=C2C(CC(N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-UHFFFAOYSA-N 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 235000001014 amino acid Nutrition 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 239000003945 anionic surfactant Substances 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000036765 blood level Effects 0.000 description 1
- 229960003669 carbenicillin Drugs 0.000 description 1
- 239000000969 carrier Substances 0.000 description 1
- 229940124587 cephalosporin Drugs 0.000 description 1
- 150000001780 cephalosporins Chemical class 0.000 description 1
- 239000002552 dosage form Substances 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 210000003736 gastrointestinal content Anatomy 0.000 description 1
- 235000013922 glutamic acid Nutrition 0.000 description 1
- 239000004220 glutamic acid Substances 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- 239000000314 lubricant Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 150000002763 monocarboxylic acids Chemical class 0.000 description 1
- 239000002736 nonionic surfactant Substances 0.000 description 1
- 125000000951 phenoxy group Chemical group [H]C1=C([H])C([H])=C(O*)C([H])=C1[H] 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 239000011241 protective layer Substances 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
- A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1467169A GB1291282A (en) | 1969-03-20 | 1969-03-20 | Improvements in pharmaceutical compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE2013040A1 true DE2013040A1 (de) | 1970-11-26 |
Family
ID=10045477
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19702013040 Pending DE2013040A1 (de) | 1969-03-20 | 1970-03-19 | Arzneimitteltablette zur oralen Verabreichung |
Country Status (6)
| Country | Link |
|---|---|
| BE (1) | BE747657A (enrdf_load_html_response) |
| CA (1) | CA930305A (enrdf_load_html_response) |
| DE (1) | DE2013040A1 (enrdf_load_html_response) |
| ES (1) | ES377723A1 (enrdf_load_html_response) |
| FR (1) | FR2035119B1 (enrdf_load_html_response) |
| GB (1) | GB1291282A (enrdf_load_html_response) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2211019C3 (de) * | 1972-03-08 | 1980-08-28 | Bayer Ag, 5090 Leverkusen | Geschmacksverbessernde Formulierungen oraler Penicilline |
| US4235900A (en) * | 1978-11-15 | 1980-11-25 | E. R. Squibb & Sons, Inc. | Cephradine compositions |
| EP0091502A1 (en) * | 1982-04-13 | 1983-10-19 | Asahi Kasei Kogyo Kabushiki Kaisha | A pharmaceutical preparation of cephalosporin for rectal administration |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB794798A (en) * | 1955-09-22 | 1958-05-07 | Nathaniel Mandel Elias | Pharmaceutical compositions |
-
1969
- 1969-03-20 GB GB1467169A patent/GB1291282A/en not_active Expired
-
1970
- 1970-03-19 DE DE19702013040 patent/DE2013040A1/de active Pending
- 1970-03-19 CA CA077836A patent/CA930305A/en not_active Expired
- 1970-03-19 BE BE747657D patent/BE747657A/xx not_active IP Right Cessation
- 1970-03-20 FR FR7010070A patent/FR2035119B1/fr not_active Expired
- 1970-03-20 ES ES377723A patent/ES377723A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| GB1291282A (en) | 1972-10-04 |
| ES377723A1 (es) | 1972-10-16 |
| FR2035119B1 (enrdf_load_html_response) | 1974-08-30 |
| FR2035119A1 (enrdf_load_html_response) | 1970-12-18 |
| CA930305A (en) | 1973-07-17 |
| BE747657A (fr) | 1970-09-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE69623634T2 (de) | Pharmazeutische zusammensetzung von l-dopa ethyl ester | |
| DE68905096T2 (de) | Niacin und guar-mehl enthaltende zusammensetzung. | |
| DE69109286T2 (de) | Pharmazeutische zusammensetzung. | |
| DE2551280A1 (de) | L-dopa-zubereitung | |
| DE60114475T2 (de) | Arzneizusammensetzung mit schnellem wirkungseintritt | |
| DE2414868A1 (de) | Arzneimittel und verfahren zu seiner herstellung | |
| LU86887A1 (de) | Multimineralstoffpraeparate mit retardwirkung | |
| DD238529A5 (de) | Verfahren zur herstellung einer pharmazeutischen zubereitung mit einem gehalt an ibuprofen | |
| DE2827018A1 (de) | Entzuendungshemmende, analgetische, gelierte salbe | |
| DE60107272T2 (de) | Eisenverbindungen | |
| CH630257A5 (en) | Sustained release formulation | |
| DE3108079A1 (de) | "nutriens-verbindungen und verfahren zu ihrer verabreichung" | |
| DE3751404T2 (de) | Verwendung von heterocyclischen Verbindungen zur Behandlung von Bewusstseinsstörungen. | |
| DE69814850T2 (de) | Paracetamol enthaltende schlickbare tablette | |
| DE69108022T3 (de) | Arzneimittel. | |
| DE2741595C2 (enrdf_load_html_response) | ||
| DE1915798C3 (de) | Antacidum-Präparat in Form einer wäßrigen Suspension | |
| DE1767017C3 (de) | Steckkapsel-Eisenpräparat | |
| DE2507354A1 (de) | Pharmazeutische zubereitung | |
| DE1938709A1 (de) | Neue Antibiotika-haltige Zusammensetzungen | |
| DE2013040A1 (de) | Arzneimitteltablette zur oralen Verabreichung | |
| DE2013039A1 (de) | Arzneimitteltablette zur oralen Verabreichung | |
| DE4216756C2 (de) | 2-Arylpropionsäure-Zubereitungen und Verfahren zu ihrer Herstellung | |
| DE3301328A1 (de) | Arzneimittel zur einleitenden bekaempfung von akuter oder chronischer, myelogener leukaemie | |
| DE2126533A1 (de) | Verfahren zur Herstellung pharma zeutischer Zubereitungen |