DE2011679A1 - Diagnostisches Mittel zur Nitritfeststellung - Google Patents
Diagnostisches Mittel zur NitritfeststellungInfo
- Publication number
- DE2011679A1 DE2011679A1 DE19702011679 DE2011679A DE2011679A1 DE 2011679 A1 DE2011679 A1 DE 2011679A1 DE 19702011679 DE19702011679 DE 19702011679 DE 2011679 A DE2011679 A DE 2011679A DE 2011679 A1 DE2011679 A1 DE 2011679A1
- Authority
- DE
- Germany
- Prior art keywords
- nitrite
- naphthyl
- acid
- sulfanilamide
- urine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- IOVCWXUNBOPUCH-UHFFFAOYSA-M Nitrite anion Chemical compound [O-]N=O IOVCWXUNBOPUCH-UHFFFAOYSA-M 0.000 title claims description 28
- 229940039227 diagnostic agent Drugs 0.000 title claims 2
- 239000000032 diagnostic agent Substances 0.000 title claims 2
- HVBSAKJJOYLTQU-UHFFFAOYSA-N 4-aminobenzenesulfonic acid Chemical compound NC1=CC=C(S(O)(=O)=O)C=C1 HVBSAKJJOYLTQU-UHFFFAOYSA-N 0.000 claims description 14
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 12
- 229940124530 sulfonamide Drugs 0.000 claims description 12
- FDDDEECHVMSUSB-UHFFFAOYSA-N sulfanilamide Chemical compound NC1=CC=C(S(N)(=O)=O)C=C1 FDDDEECHVMSUSB-UHFFFAOYSA-N 0.000 claims description 11
- 210000002700 urine Anatomy 0.000 claims description 11
- 239000003795 chemical substances by application Substances 0.000 claims description 10
- 229950000244 sulfanilic acid Drugs 0.000 claims description 7
- 239000011780 sodium chloride Substances 0.000 claims description 6
- 239000002253 acid Substances 0.000 claims description 4
- 238000001514 detection method Methods 0.000 claims description 2
- 150000007524 organic acids Chemical class 0.000 claims description 2
- 238000006243 chemical reaction Methods 0.000 description 17
- 239000000203 mixture Substances 0.000 description 9
- 241000894006 Bacteria Species 0.000 description 8
- 201000004538 Bacteriuria Diseases 0.000 description 7
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 6
- 150000001875 compounds Chemical class 0.000 description 6
- 239000000126 substance Substances 0.000 description 5
- 229910002651 NO3 Inorganic materials 0.000 description 4
- NHNBFGGVMKEFGY-UHFFFAOYSA-N Nitrate Chemical compound [O-][N+]([O-])=O NHNBFGGVMKEFGY-UHFFFAOYSA-N 0.000 description 4
- MZNYWPRCVDMOJG-UHFFFAOYSA-N N-(1-naphthyl)ethylenediamine dihydrochloride Chemical compound [Cl-].[Cl-].C1=CC=C2C([NH2+]CC[NH3+])=CC=CC2=C1 MZNYWPRCVDMOJG-UHFFFAOYSA-N 0.000 description 3
- 239000000987 azo dye Substances 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- NULAJYZBOLVQPQ-UHFFFAOYSA-N N-(1-naphthyl)ethylenediamine Chemical compound C1=CC=C2C(NCCN)=CC=CC2=C1 NULAJYZBOLVQPQ-UHFFFAOYSA-N 0.000 description 2
- 150000001768 cations Chemical class 0.000 description 2
- 238000006193 diazotization reaction Methods 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- ZYECOAILUNWEAL-NUDFZHEQSA-N (4z)-4-[[2-methoxy-5-(phenylcarbamoyl)phenyl]hydrazinylidene]-n-(3-nitrophenyl)-3-oxonaphthalene-2-carboxamide Chemical compound COC1=CC=C(C(=O)NC=2C=CC=CC=2)C=C1N\N=C(C1=CC=CC=C1C=1)/C(=O)C=1C(=O)NC1=CC=CC([N+]([O-])=O)=C1 ZYECOAILUNWEAL-NUDFZHEQSA-N 0.000 description 1
- 125000001637 1-naphthyl group Chemical group [H]C1=C([H])C([H])=C2C(*)=C([H])C([H])=C([H])C2=C1[H] 0.000 description 1
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 description 1
- 241000588767 Proteus vulgaris Species 0.000 description 1
- 241000607142 Salmonella Species 0.000 description 1
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 1
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 244000052616 bacterial pathogen Species 0.000 description 1
- 239000013043 chemical agent Substances 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 238000004040 coloring Methods 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 150000001989 diazonium salts Chemical class 0.000 description 1
- 210000002615 epidermis Anatomy 0.000 description 1
- 230000037406 food intake Effects 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 208000017169 kidney disease Diseases 0.000 description 1
- MJIHNNLFOKEZEW-UHFFFAOYSA-N lansoprazole Chemical compound CC1=C(OCC(F)(F)F)C=CN=C1CS(=O)C1=NC2=CC=CC=C2N1 MJIHNNLFOKEZEW-UHFFFAOYSA-N 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 230000002503 metabolic effect Effects 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- WZRRZVUZWWMSKH-UHFFFAOYSA-N n'-naphthalen-1-ylethane-1,2-diamine;hydrochloride Chemical compound Cl.C1=CC=C2C(NCCN)=CC=CC2=C1 WZRRZVUZWWMSKH-UHFFFAOYSA-N 0.000 description 1
- 201000008383 nephritis Diseases 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 235000021135 plant-based food Nutrition 0.000 description 1
- 229940007042 proteus vulgaris Drugs 0.000 description 1
- 230000001603 reducing effect Effects 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 125000000565 sulfonamide group Chemical group 0.000 description 1
- -1 sulphonamide compound Chemical class 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- 235000015149 toffees Nutrition 0.000 description 1
- 208000019206 urinary tract infection Diseases 0.000 description 1
- 201000009482 yaws Diseases 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
- C12Q1/12—Nitrate to nitrite reducing bacteria
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/84—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving inorganic compounds or pH
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Biophysics (AREA)
- Inorganic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Exhaust Silencers (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE519369A SE330272B (enrdf_load_stackoverflow) | 1969-04-14 | 1969-04-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE2011679A1 true DE2011679A1 (de) | 1970-10-15 |
Family
ID=20265901
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19702011679 Pending DE2011679A1 (de) | 1969-04-14 | 1970-03-12 | Diagnostisches Mittel zur Nitritfeststellung |
Country Status (9)
| Country | Link |
|---|---|
| AT (4) | AT309692B (enrdf_load_stackoverflow) |
| BE (1) | BE747393A (enrdf_load_stackoverflow) |
| CH (1) | CH555543A (enrdf_load_stackoverflow) |
| DE (1) | DE2011679A1 (enrdf_load_stackoverflow) |
| DK (1) | DK132354C (enrdf_load_stackoverflow) |
| GB (1) | GB1282653A (enrdf_load_stackoverflow) |
| NL (1) | NL7004369A (enrdf_load_stackoverflow) |
| NO (1) | NO127027B (enrdf_load_stackoverflow) |
| SE (1) | SE330272B (enrdf_load_stackoverflow) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0160240A2 (en) | 1984-05-02 | 1985-11-06 | TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION | Test piece for detecting nitrite |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2653888B1 (fr) * | 1989-10-27 | 1993-07-09 | Nicoloff Thierry | Procedes et reactifs colorimetriques pour detecter quantitativement des bacteries pathogenes dans l'eau. |
| US6861262B2 (en) | 2000-03-03 | 2005-03-01 | Quest Diagnostics Investments Incorporated | Composition and method for detecting an adulterant in an aqueous sample |
| DE60039505D1 (de) * | 1999-03-04 | 2008-08-28 | Quest Diagnostics Invest Inc | Reagens und verfahren zum nachweis von verfälschungsmitteln in wässrigen proben |
| WO2011017317A1 (en) * | 2009-08-04 | 2011-02-10 | 3M Innovative Properties Company | Method of detecting oxides of nitrogen |
| WO2025019992A1 (zh) * | 2023-07-21 | 2025-01-30 | 深圳先进技术研究院 | 一种检测微量亚硝酸盐的试剂盒、检测系统及其相关方法 |
-
1969
- 1969-04-14 SE SE519369A patent/SE330272B/xx unknown
-
1970
- 1970-03-09 CH CH341270A patent/CH555543A/xx not_active IP Right Cessation
- 1970-03-10 DK DK117670A patent/DK132354C/da active
- 1970-03-12 NO NO88870A patent/NO127027B/no unknown
- 1970-03-12 DE DE19702011679 patent/DE2011679A1/de active Pending
- 1970-03-16 BE BE747393D patent/BE747393A/xx unknown
- 1970-03-20 AT AT646071A patent/AT309692B/de not_active IP Right Cessation
- 1970-03-20 AT AT645971A patent/AT307623B/de not_active IP Right Cessation
- 1970-03-20 AT AT646171A patent/AT309693B/de not_active IP Right Cessation
- 1970-03-20 AT AT261070A patent/AT301761B/de not_active IP Right Cessation
- 1970-03-26 NL NL7004369A patent/NL7004369A/xx unknown
- 1970-03-31 GB GB1530470A patent/GB1282653A/en not_active Expired
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0160240A2 (en) | 1984-05-02 | 1985-11-06 | TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION | Test piece for detecting nitrite |
| EP0160240A3 (en) * | 1984-05-02 | 1987-07-29 | Terumo Kabushiki Kaisha Trading As Terumo Corporation | Test piece for detecting nitrite |
Also Published As
| Publication number | Publication date |
|---|---|
| AT307623B (de) | 1973-05-25 |
| DK132354B (da) | 1975-11-24 |
| AT309693B (de) | 1973-08-27 |
| BE747393A (fr) | 1970-08-31 |
| NL7004369A (enrdf_load_stackoverflow) | 1970-10-16 |
| AT301761B (de) | 1972-09-25 |
| CH555543A (de) | 1974-10-31 |
| DK132354C (da) | 1976-05-03 |
| GB1282653A (en) | 1972-07-19 |
| AT309692B (de) | 1973-08-27 |
| SE330272B (enrdf_load_stackoverflow) | 1970-11-09 |
| NO127027B (enrdf_load_stackoverflow) | 1973-04-24 |
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