DE2011330A1 - Vorrichtung zur Entfernung von Harnstoff aus dem Blut eines Kranken durch Dialyse oder Ultrafiltration - Google Patents
Vorrichtung zur Entfernung von Harnstoff aus dem Blut eines Kranken durch Dialyse oder UltrafiltrationInfo
- Publication number
- DE2011330A1 DE2011330A1 DE19702011330 DE2011330A DE2011330A1 DE 2011330 A1 DE2011330 A1 DE 2011330A1 DE 19702011330 DE19702011330 DE 19702011330 DE 2011330 A DE2011330 A DE 2011330A DE 2011330 A1 DE2011330 A1 DE 2011330A1
- Authority
- DE
- Germany
- Prior art keywords
- column
- dialysis
- electrodialyzer
- patient
- urea
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 title claims description 16
- 239000004202 carbamide Substances 0.000 title claims description 16
- 239000008280 blood Substances 0.000 title claims description 7
- 210000004369 blood Anatomy 0.000 title claims description 7
- 238000000502 dialysis Methods 0.000 title claims description 6
- 238000000108 ultra-filtration Methods 0.000 title claims description 6
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 14
- 239000000385 dialysis solution Substances 0.000 claims description 13
- 108010046334 Urease Proteins 0.000 claims description 10
- 150000002500 ions Chemical class 0.000 claims description 9
- 238000010790 dilution Methods 0.000 claims description 7
- 239000012895 dilution Substances 0.000 claims description 7
- 150000001450 anions Chemical class 0.000 claims description 5
- 239000007788 liquid Substances 0.000 claims description 5
- 239000012528 membrane Substances 0.000 claims description 5
- 239000011347 resin Substances 0.000 claims description 5
- 229920005989 resin Polymers 0.000 claims description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 5
- 239000002775 capsule Substances 0.000 claims description 3
- 150000001768 cations Chemical class 0.000 claims description 3
- 238000007654 immersion Methods 0.000 claims description 2
- 239000000463 material Substances 0.000 claims description 2
- 230000002035 prolonged effect Effects 0.000 claims description 2
- DDRJAANPRJIHGJ-UHFFFAOYSA-N creatinine Chemical compound CN1CC(=O)NC1=N DDRJAANPRJIHGJ-UHFFFAOYSA-N 0.000 description 6
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 description 4
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 4
- 238000004140 cleaning Methods 0.000 description 4
- LEHOTFFKMJEONL-UHFFFAOYSA-N Uric Acid Chemical compound N1C(=O)NC(=O)C2=C1NC(=O)N2 LEHOTFFKMJEONL-UHFFFAOYSA-N 0.000 description 3
- TVWHNULVHGKJHS-UHFFFAOYSA-N Uric acid Natural products N1C(=O)NC(=O)C2NC(=O)NC21 TVWHNULVHGKJHS-UHFFFAOYSA-N 0.000 description 3
- 229940109239 creatinine Drugs 0.000 description 3
- 239000012266 salt solution Substances 0.000 description 3
- 229940116269 uric acid Drugs 0.000 description 3
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 description 2
- ATRRKUHOCOJYRX-UHFFFAOYSA-N Ammonium bicarbonate Chemical class [NH4+].OC([O-])=O ATRRKUHOCOJYRX-UHFFFAOYSA-N 0.000 description 2
- 229910019142 PO4 Inorganic materials 0.000 description 2
- 239000001099 ammonium carbonate Substances 0.000 description 2
- 235000012501 ammonium carbonate Nutrition 0.000 description 2
- 239000003957 anion exchange resin Substances 0.000 description 2
- 239000003729 cation exchange resin Substances 0.000 description 2
- 235000021317 phosphate Nutrition 0.000 description 2
- 229910052708 sodium Inorganic materials 0.000 description 2
- 239000011734 sodium Substances 0.000 description 2
- 229910000029 sodium carbonate Inorganic materials 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 150000003467 sulfuric acid derivatives Chemical class 0.000 description 2
- NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 description 1
- LSNNMFCWUKXFEE-UHFFFAOYSA-M Bisulfite Chemical compound OS([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-M 0.000 description 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- -1 NaCl Chemical class 0.000 description 1
- 150000001242 acetic acid derivatives Chemical class 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 125000000129 anionic group Chemical group 0.000 description 1
- 229940023913 cation exchange resins Drugs 0.000 description 1
- 150000003841 chloride salts Chemical class 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 239000003792 electrolyte Substances 0.000 description 1
- 230000002503 metabolic effect Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 150000003013 phosphoric acid derivatives Chemical class 0.000 description 1
- 238000004064 recycling Methods 0.000 description 1
- 238000007665 sagging Methods 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/42—Electrodialysis; Electro-osmosis ; Electro-ultrafiltration; Membrane capacitive deionization
- B01D61/44—Ion-selective electrodialysis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1694—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes with recirculating dialysing liquid
- A61M1/1696—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes with recirculating dialysing liquid with dialysate regeneration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
- A61M1/3472—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
- A61M1/3472—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
- A61M1/3486—Biological, chemical treatment, e.g. chemical precipitation; treatment by absorbents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/42—Electrodialysis; Electro-osmosis ; Electro-ultrafiltration; Membrane capacitive deionization
- B01D61/44—Ion-selective electrodialysis
- B01D61/46—Apparatus therefor
- B01D61/461—Apparatus therefor comprising only a single cell, only one anion or cation exchange membrane or one pair of anion and cation membranes
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Water Supply & Treatment (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Anesthesiology (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- Vascular Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Chemical & Material Sciences (AREA)
- Emergency Medicine (AREA)
- Biodiversity & Conservation Biology (AREA)
- Cell Biology (AREA)
- Molecular Biology (AREA)
- External Artificial Organs (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR6907130A FR2036413A5 (enExample) | 1969-03-13 | 1969-03-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE2011330A1 true DE2011330A1 (de) | 1971-03-18 |
Family
ID=9030579
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19702011330 Pending DE2011330A1 (de) | 1969-03-13 | 1970-03-10 | Vorrichtung zur Entfernung von Harnstoff aus dem Blut eines Kranken durch Dialyse oder Ultrafiltration |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US3617545A (enExample) |
| BE (1) | BE747177A (enExample) |
| DE (1) | DE2011330A1 (enExample) |
| FR (1) | FR2036413A5 (enExample) |
| NL (1) | NL7003109A (enExample) |
Families Citing this family (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4061141A (en) * | 1969-03-21 | 1977-12-06 | Viktor Holger Hyden | Apparatus and method for selectively separating amino acids and defined proteins in blood |
| DE2239254C2 (de) * | 1970-12-30 | 1983-08-04 | Organon Teknika Corp., Oklahoma City, Okla. | "Säule zur Regenerierung einer zirkulierenden Dialysatlösung und Verwendung dieser Säule". |
| FR2129165A5 (enExample) * | 1971-03-17 | 1972-10-27 | Rhone Poulenc Sa | |
| FR2129164A5 (enExample) * | 1971-03-17 | 1972-10-27 | Rhone Poulenc Sa | |
| FR2171934B1 (enExample) * | 1972-02-16 | 1974-09-13 | Rhone Poulenc Sa | |
| JPS5226076B2 (enExample) * | 1972-10-06 | 1977-07-12 | ||
| US3989613A (en) * | 1973-05-16 | 1976-11-02 | The Dow Chemical Company | Continuous balanced flow fixed boundary electrophoresis |
| US4043895A (en) * | 1973-05-16 | 1977-08-23 | The Dow Chemical Company | Electrophoresis apparatus |
| US4094775A (en) * | 1977-02-28 | 1978-06-13 | California Institute Of Technology | Dialysis system |
| NL7703937A (nl) * | 1977-04-12 | 1978-10-16 | Organon Teknika Bv | Inrichting voorzien van een sorbent voor het zuiveren van bloed; een voor orale toepassing geschikt sorbent en een werkwijze voor vervaar- diging van het sorbent. |
| DE3040470A1 (de) * | 1980-10-27 | 1982-06-03 | Siemens AG, 1000 Berlin und 8000 München | Verfahren und vorrichtung zur indirekten oxidation von harnstoff |
| US4473449A (en) * | 1982-09-22 | 1984-09-25 | The Board Of Trustees Of The Leland Stanford Junior University | Flowthrough electrochemical hemodialysate regeneration |
| US4663006A (en) * | 1983-09-08 | 1987-05-05 | The Montefiore Hospital Association Of Western Pennsylvania | Cyclic controlled electrolysis |
| US6579460B1 (en) * | 2001-03-13 | 2003-06-17 | Uop Llc | Process and composition for removing toxins from bodily fluids |
| US7241272B2 (en) | 2001-11-13 | 2007-07-10 | Baxter International Inc. | Method and composition for removing uremic toxins in dialysis processes |
| WO2003080225A1 (en) * | 2002-03-18 | 2003-10-02 | Ionics, Incorporated | Upw treatment and system with organic nitrogen removal |
| US7175606B2 (en) | 2002-05-24 | 2007-02-13 | Baxter International Inc. | Disposable medical fluid unit having rigid frame |
| US7153286B2 (en) | 2002-05-24 | 2006-12-26 | Baxter International Inc. | Automated dialysis system |
| US7238164B2 (en) | 2002-07-19 | 2007-07-03 | Baxter International Inc. | Systems, methods and apparatuses for pumping cassette-based therapies |
| EP1523351B1 (en) | 2002-07-19 | 2010-01-06 | Baxter International Inc. | System for peritoneal dialysis |
| ATE505223T1 (de) | 2002-07-19 | 2011-04-15 | Baxter Int | System für die peritonealdialyse |
| MXPA05000817A (es) | 2002-07-19 | 2005-04-28 | Baxter Int | Sistemas y metodos para realizar dialisis peritoneal. |
| US8029454B2 (en) | 2003-11-05 | 2011-10-04 | Baxter International Inc. | High convection home hemodialysis/hemofiltration and sorbent system |
| EP1701752B1 (en) * | 2003-12-24 | 2016-05-18 | Chemica Technologies, Inc. | Dialysate regeneration system for portable human dialysis |
| US20050262811A1 (en) * | 2004-05-27 | 2005-12-01 | Mahmood Mohiuddin | Sterilization process for iodine-containing antimicrobial topical solutions |
| US9514283B2 (en) | 2008-07-09 | 2016-12-06 | Baxter International Inc. | Dialysis system having inventory management including online dextrose mixing |
| US8057679B2 (en) | 2008-07-09 | 2011-11-15 | Baxter International Inc. | Dialysis system having trending and alert generation |
| US8062513B2 (en) | 2008-07-09 | 2011-11-22 | Baxter International Inc. | Dialysis system and machine having therapy prescription recall |
| US20100051552A1 (en) * | 2008-08-28 | 2010-03-04 | Baxter International Inc. | In-line sensors for dialysis applications |
| WO2010102190A1 (en) | 2009-03-06 | 2010-09-10 | Baxter International Inc. | Hemodialysis and peritoneal dialysis systems having electrodeionization capabilities |
| US9005440B2 (en) | 2009-03-06 | 2015-04-14 | Baxter International Inc. | Hemodialysis and peritoneal dialysis systems having electrodialysis and electrodeionization capabilities |
| US8404091B2 (en) * | 2009-08-27 | 2013-03-26 | Baxter International Inc. | Dialysis treatment devices for removing urea |
| RU2472777C1 (ru) * | 2011-11-23 | 2013-01-20 | Фарид Алекович Батуллин | Способ получения кристаллического карбамида высокой очистки |
| EP2900296B1 (en) * | 2013-03-12 | 2016-10-19 | Baxter International Inc. | Hemodialysis and peritoneal dialysis systems having electrodialysis and electrodeionization capabilities |
| US9884145B2 (en) | 2013-11-26 | 2018-02-06 | Medtronic, Inc. | Parallel modules for in-line recharging of sorbents using alternate duty cycles |
| US10537875B2 (en) | 2013-11-26 | 2020-01-21 | Medtronic, Inc. | Precision recharging of sorbent materials using patient and session data |
| US10357757B2 (en) | 2014-06-24 | 2019-07-23 | Medtronic, Inc. | Stacked sorbent assembly |
| WO2016024217A1 (en) * | 2014-08-11 | 2016-02-18 | Universita' Degli Studi Di Milano - Bicocca | Extracorporeal circuit system for the treatment of hydroelectrolyte and acid-base blood imbalances |
| WO2016190853A1 (en) * | 2015-05-26 | 2016-12-01 | Medtronic, Inc. | Multi-use sorbent cartridge |
| JP2018524718A (ja) | 2015-06-25 | 2018-08-30 | ガンブロ・ルンディア・エービーGambro Lundia Ab | 分散データベースを有する医療装置システム及び方法 |
| US10981148B2 (en) | 2016-11-29 | 2021-04-20 | Medtronic, Inc. | Zirconium oxide module conditioning |
| CA3044724A1 (en) | 2016-12-21 | 2018-06-28 | Gambro Lundia Ab | Medical device system including information technology infrastructure having secure cluster domain supporting external domain |
| US10960381B2 (en) | 2017-06-15 | 2021-03-30 | Medtronic, Inc. | Zirconium phosphate disinfection recharging and conditioning |
| US12285552B2 (en) | 2018-08-14 | 2025-04-29 | Mozarc Medical Us Llc | Precision dialysis therapy based on sorbent effluent analysis |
| US11213616B2 (en) | 2018-08-24 | 2022-01-04 | Medtronic, Inc. | Recharge solution for zirconium phosphate |
| US12397093B2 (en) | 2021-05-18 | 2025-08-26 | Mozarc Medical Us Llc | Sorbent cartridge designs |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3268441A (en) * | 1963-05-21 | 1966-08-23 | Ionics | Water recovery by electrodialysis |
| US3463728A (en) * | 1967-04-28 | 1969-08-26 | Us Health Education & Welfare | Dialysate capacity augmentation process |
-
1969
- 1969-03-13 FR FR6907130A patent/FR2036413A5/fr not_active Expired
-
1970
- 1970-03-04 NL NL7003109A patent/NL7003109A/xx unknown
- 1970-03-10 DE DE19702011330 patent/DE2011330A1/de active Pending
- 1970-03-11 BE BE747177D patent/BE747177A/xx unknown
- 1970-03-12 US US19018A patent/US3617545A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| FR2036413A5 (enExample) | 1970-12-24 |
| NL7003109A (enExample) | 1970-09-15 |
| US3617545A (en) | 1971-11-02 |
| BE747177A (fr) | 1970-09-11 |
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