DE2000818A1 - Verfahren zur Herstellung von hochkonzentrierten Nisinkonzentraten - Google Patents
Verfahren zur Herstellung von hochkonzentrierten NisinkonzentratenInfo
- Publication number
- DE2000818A1 DE2000818A1 DE19702000818 DE2000818A DE2000818A1 DE 2000818 A1 DE2000818 A1 DE 2000818A1 DE 19702000818 DE19702000818 DE 19702000818 DE 2000818 A DE2000818 A DE 2000818A DE 2000818 A1 DE2000818 A1 DE 2000818A1
- Authority
- DE
- Germany
- Prior art keywords
- nisin
- foam
- milk
- temperature
- whey
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108010053775 Nisin Proteins 0.000 title claims description 22
- NVNLLIYOARQCIX-MSHCCFNRSA-N Nisin Chemical compound N1C(=O)[C@@H](CC(C)C)NC(=O)C(=C)NC(=O)[C@@H]([C@H](C)CC)NC(=O)[C@@H](NC(=O)C(=C/C)/NC(=O)[C@H](N)[C@H](C)CC)CSC[C@@H]1C(=O)N[C@@H]1C(=O)N2CCC[C@@H]2C(=O)NCC(=O)N[C@@H](C(=O)N[C@H](CCCCN)C(=O)N[C@@H]2C(NCC(=O)N[C@H](C)C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCSC)C(=O)NCC(=O)N[C@H](CS[C@@H]2C)C(=O)N[C@H](CC(N)=O)C(=O)N[C@H](CCSC)C(=O)N[C@H](CCCCN)C(=O)N[C@@H]2C(N[C@H](C)C(=O)N[C@@H]3C(=O)N[C@@H](C(N[C@H](CC=4NC=NC=4)C(=O)N[C@H](CS[C@@H]3C)C(=O)N[C@H](CO)C(=O)N[C@H]([C@H](C)CC)C(=O)N[C@H](CC=3NC=NC=3)C(=O)N[C@H](C(C)C)C(=O)NC(=C)C(=O)N[C@H](CCCCN)C(O)=O)=O)CS[C@@H]2C)=O)=O)CS[C@@H]1C NVNLLIYOARQCIX-MSHCCFNRSA-N 0.000 title claims description 22
- 239000004309 nisin Substances 0.000 title claims description 22
- 235000010297 nisin Nutrition 0.000 title claims description 22
- 238000000034 method Methods 0.000 title claims description 21
- 239000012141 concentrate Substances 0.000 title claims description 16
- 238000004519 manufacturing process Methods 0.000 title description 4
- 238000000855 fermentation Methods 0.000 claims description 21
- 230000004151 fermentation Effects 0.000 claims description 21
- 235000010633 broth Nutrition 0.000 claims description 19
- 239000006260 foam Substances 0.000 claims description 16
- 235000008504 concentrate Nutrition 0.000 claims description 15
- 239000002244 precipitate Substances 0.000 claims description 15
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 claims description 10
- 239000005862 Whey Substances 0.000 claims description 10
- 102000007544 Whey Proteins Human genes 0.000 claims description 10
- 108010046377 Whey Proteins Proteins 0.000 claims description 10
- 239000007788 liquid Substances 0.000 claims description 8
- 235000018102 proteins Nutrition 0.000 claims description 6
- 108090000623 proteins and genes Proteins 0.000 claims description 6
- 102000004169 proteins and genes Human genes 0.000 claims description 6
- 239000000284 extract Substances 0.000 claims description 5
- 239000000706 filtrate Substances 0.000 claims description 5
- 235000013336 milk Nutrition 0.000 claims description 4
- 239000008267 milk Substances 0.000 claims description 4
- 210000004080 milk Anatomy 0.000 claims description 4
- 102000057297 Pepsin A Human genes 0.000 claims description 3
- 108090000284 Pepsin A Proteins 0.000 claims description 3
- 244000061456 Solanum tuberosum Species 0.000 claims description 3
- 235000002595 Solanum tuberosum Nutrition 0.000 claims description 3
- 244000005700 microbiome Species 0.000 claims description 3
- 235000015097 nutrients Nutrition 0.000 claims description 3
- 229940111202 pepsin Drugs 0.000 claims description 3
- 230000000405 serological effect Effects 0.000 claims description 3
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims description 2
- 244000057717 Streptococcus lactis Species 0.000 claims description 2
- 235000014897 Streptococcus lactis Nutrition 0.000 claims description 2
- 238000000605 extraction Methods 0.000 claims description 2
- 239000008103 glucose Substances 0.000 claims description 2
- 235000020183 skimmed milk Nutrition 0.000 claims description 2
- 239000006188 syrup Substances 0.000 claims description 2
- 235000020357 syrup Nutrition 0.000 claims description 2
- 102000014171 Milk Proteins Human genes 0.000 claims 1
- 108010011756 Milk Proteins Proteins 0.000 claims 1
- 235000020186 condensed milk Nutrition 0.000 claims 1
- 235000021239 milk protein Nutrition 0.000 claims 1
- 238000011084 recovery Methods 0.000 claims 1
- 238000000926 separation method Methods 0.000 claims 1
- 239000000725 suspension Substances 0.000 claims 1
- 235000008939 whole milk Nutrition 0.000 claims 1
- 230000000694 effects Effects 0.000 description 8
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 4
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
- 239000005018 casein Substances 0.000 description 3
- 235000021240 caseins Nutrition 0.000 description 3
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 description 1
- 241001112695 Clostridiales Species 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000001110 calcium chloride Substances 0.000 description 1
- 229910001628 calcium chloride Inorganic materials 0.000 description 1
- 244000309466 calf Species 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 235000015140 cultured milk Nutrition 0.000 description 1
- 239000004088 foaming agent Substances 0.000 description 1
- 239000003112 inhibitor Substances 0.000 description 1
- 238000009413 insulation Methods 0.000 description 1
- 229920001184 polypeptide Polymers 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 230000006920 protein precipitation Effects 0.000 description 1
- 229940108461 rennet Drugs 0.000 description 1
- 108010058314 rennet Proteins 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 238000010626 work up procedure Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL13123369A PL68835B1 (enrdf_load_stackoverflow) | 1969-01-17 | 1969-01-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE2000818A1 true DE2000818A1 (de) | 1970-09-03 |
Family
ID=19950338
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19702000818 Pending DE2000818A1 (de) | 1969-01-17 | 1970-01-09 | Verfahren zur Herstellung von hochkonzentrierten Nisinkonzentraten |
Country Status (7)
| Country | Link |
|---|---|
| BG (1) | BG20822A3 (enrdf_load_stackoverflow) |
| CS (1) | CS172321B2 (enrdf_load_stackoverflow) |
| DE (1) | DE2000818A1 (enrdf_load_stackoverflow) |
| GB (1) | GB1295232A (enrdf_load_stackoverflow) |
| PL (1) | PL68835B1 (enrdf_load_stackoverflow) |
| RO (1) | RO60349A (enrdf_load_stackoverflow) |
| SU (1) | SU427516A3 (enrdf_load_stackoverflow) |
-
1969
- 1969-01-17 PL PL13123369A patent/PL68835B1/xx unknown
-
1970
- 1970-01-07 SU SU1393515A patent/SU427516A3/ru active
- 1970-01-08 GB GB1295232D patent/GB1295232A/en not_active Expired
- 1970-01-09 DE DE19702000818 patent/DE2000818A1/de active Pending
- 1970-01-14 CS CS28970A patent/CS172321B2/cs unknown
- 1970-01-15 BG BG1375070A patent/BG20822A3/xx unknown
- 1970-01-17 RO RO6216870A patent/RO60349A/ro unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CS172321B2 (enrdf_load_stackoverflow) | 1976-12-29 |
| RO60349A (enrdf_load_stackoverflow) | 1976-07-15 |
| PL68835B1 (enrdf_load_stackoverflow) | 1973-02-28 |
| SU427516A3 (ru) | 1974-05-05 |
| GB1295232A (enrdf_load_stackoverflow) | 1972-11-08 |
| BG20822A3 (enrdf_load_stackoverflow) | 1975-12-20 |
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