DE19956131A1 - Neue für das pfk-Gen codierende Nukleotidsequenzen - Google Patents
Neue für das pfk-Gen codierende NukleotidsequenzenInfo
- Publication number
- DE19956131A1 DE19956131A1 DE19956131A DE19956131A DE19956131A1 DE 19956131 A1 DE19956131 A1 DE 19956131A1 DE 19956131 A DE19956131 A DE 19956131A DE 19956131 A DE19956131 A DE 19956131A DE 19956131 A1 DE19956131 A1 DE 19956131A1
- Authority
- DE
- Germany
- Prior art keywords
- polynucleotide
- sequence
- amino acid
- lysine
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
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- AVKUERGKIZMTKX-NJBDSQKTSA-N ampicillin Chemical compound C1([C@@H](N)C(=O)N[C@H]2[C@H]3SC([C@@H](N3C2=O)C(O)=O)(C)C)=CC=CC=C1 AVKUERGKIZMTKX-NJBDSQKTSA-N 0.000 description 1
- 230000003321 amplification Effects 0.000 description 1
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- 235000003704 aspartic acid Nutrition 0.000 description 1
- 150000007514 bases Chemical class 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- OQFSQFPPLPISGP-UHFFFAOYSA-N beta-carboxyaspartic acid Natural products OC(=O)C(N)C(C(O)=O)C(O)=O OQFSQFPPLPISGP-UHFFFAOYSA-N 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 238000009395 breeding Methods 0.000 description 1
- 230000001488 breeding effect Effects 0.000 description 1
- 229940041514 candida albicans extract Drugs 0.000 description 1
- 239000004202 carbamide Substances 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 235000014633 carbohydrates Nutrition 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 239000013611 chromosomal DNA Substances 0.000 description 1
- 238000010367 cloning Methods 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 235000005822 corn Nutrition 0.000 description 1
- 238000012364 cultivation method Methods 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 238000001212 derivatisation Methods 0.000 description 1
- MNNHAPBLZZVQHP-UHFFFAOYSA-N diammonium hydrogen phosphate Chemical compound [NH4+].[NH4+].OP([O-])([O-])=O MNNHAPBLZZVQHP-UHFFFAOYSA-N 0.000 description 1
- AIUDWMLXCFRVDR-UHFFFAOYSA-N dimethyl 2-(3-ethyl-3-methylpentyl)propanedioate Chemical class CCC(C)(CC)CCC(C(=O)OC)C(=O)OC AIUDWMLXCFRVDR-UHFFFAOYSA-N 0.000 description 1
- ZPWVASYFFYYZEW-UHFFFAOYSA-L dipotassium hydrogen phosphate Chemical compound [K+].[K+].OP([O-])([O-])=O ZPWVASYFFYYZEW-UHFFFAOYSA-L 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 239000003925 fat Substances 0.000 description 1
- 235000019197 fats Nutrition 0.000 description 1
- 230000005021 gait Effects 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 238000010353 genetic engineering Methods 0.000 description 1
- 230000034659 glycolysis Effects 0.000 description 1
- 239000003630 growth substance Substances 0.000 description 1
- 238000002744 homologous recombination Methods 0.000 description 1
- 230000006801 homologous recombination Effects 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 150000002484 inorganic compounds Chemical class 0.000 description 1
- 229910010272 inorganic material Inorganic materials 0.000 description 1
- 230000010354 integration Effects 0.000 description 1
- 230000003834 intracellular effect Effects 0.000 description 1
- 238000004255 ion exchange chromatography Methods 0.000 description 1
- 229910000358 iron sulfate Inorganic materials 0.000 description 1
- BAUYGSIQEAFULO-UHFFFAOYSA-L iron(2+) sulfate (anhydrous) Chemical compound [Fe+2].[O-]S([O-])(=O)=O BAUYGSIQEAFULO-UHFFFAOYSA-L 0.000 description 1
- -1 linoleic acid, alcohols Chemical class 0.000 description 1
- 229910052943 magnesium sulfate Inorganic materials 0.000 description 1
- 235000019341 magnesium sulphate Nutrition 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 239000002609 medium Substances 0.000 description 1
- 239000013028 medium composition Substances 0.000 description 1
- 239000002207 metabolite Substances 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 150000002739 metals Chemical class 0.000 description 1
- 239000013586 microbial product Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 229910000402 monopotassium phosphate Inorganic materials 0.000 description 1
- 235000019796 monopotassium phosphate Nutrition 0.000 description 1
- 238000002703 mutagenesis Methods 0.000 description 1
- 231100000350 mutagenesis Toxicity 0.000 description 1
- ZIUHHBKFKCYYJD-UHFFFAOYSA-N n,n'-methylenebisacrylamide Chemical compound C=CC(=O)NCNC(=O)C=C ZIUHHBKFKCYYJD-UHFFFAOYSA-N 0.000 description 1
- WQEPLUUGTLDZJY-UHFFFAOYSA-N n-Pentadecanoic acid Natural products CCCCCCCCCCCCCCC(O)=O WQEPLUUGTLDZJY-UHFFFAOYSA-N 0.000 description 1
- FEMOMIGRRWSMCU-UHFFFAOYSA-N ninhydrin Chemical compound C1=CC=C2C(=O)C(O)(O)C(=O)C2=C1 FEMOMIGRRWSMCU-UHFFFAOYSA-N 0.000 description 1
- 238000003199 nucleic acid amplification method Methods 0.000 description 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 1
- 235000014593 oils and fats Nutrition 0.000 description 1
- 238000002515 oligonucleotide synthesis Methods 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 235000005985 organic acids Nutrition 0.000 description 1
- 125000001477 organic nitrogen group Chemical group 0.000 description 1
- 238000012261 overproduction Methods 0.000 description 1
- 239000000312 peanut oil Substances 0.000 description 1
- 235000019319 peptone Nutrition 0.000 description 1
- 229940066779 peptones Drugs 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- CWCMIVBLVUHDHK-ZSNHEYEWSA-N phleomycin D1 Chemical compound N([C@H](C(=O)N[C@H](C)[C@@H](O)[C@H](C)C(=O)N[C@@H]([C@H](O)C)C(=O)NCCC=1SC[C@@H](N=1)C=1SC=C(N=1)C(=O)NCCCCNC(N)=N)[C@@H](O[C@H]1[C@H]([C@@H](O)[C@H](O)[C@H](CO)O1)O[C@@H]1[C@H]([C@@H](OC(N)=O)[C@H](O)[C@@H](CO)O1)O)C=1N=CNC=1)C(=O)C1=NC([C@H](CC(N)=O)NC[C@H](N)C(N)=O)=NC(N)=C1C CWCMIVBLVUHDHK-ZSNHEYEWSA-N 0.000 description 1
- PJNZPQUBCPKICU-UHFFFAOYSA-N phosphoric acid;potassium Chemical compound [K].OP(O)(O)=O PJNZPQUBCPKICU-UHFFFAOYSA-N 0.000 description 1
- 102000020233 phosphotransferase Human genes 0.000 description 1
- 238000013492 plasmid preparation Methods 0.000 description 1
- 229920001522 polyglycol ester Polymers 0.000 description 1
- 235000011118 potassium hydroxide Nutrition 0.000 description 1
- 239000002243 precursor Substances 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 230000006798 recombination Effects 0.000 description 1
- 238000005215 recombination Methods 0.000 description 1
- 230000002787 reinforcement Effects 0.000 description 1
- 230000003252 repetitive effect Effects 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 238000007086 side reaction Methods 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 235000011121 sodium hydroxide Nutrition 0.000 description 1
- 239000004455 soybean meal Substances 0.000 description 1
- 239000003549 soybean oil Substances 0.000 description 1
- 235000012424 soybean oil Nutrition 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 239000002600 sunflower oil Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 230000009897 systematic effect Effects 0.000 description 1
- 230000004102 tricarboxylic acid cycle Effects 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 239000012138 yeast extract Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Priority Applications (16)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19956131A DE19956131A1 (de) | 1999-11-23 | 1999-11-23 | Neue für das pfk-Gen codierende Nukleotidsequenzen |
| SK1736-2000A SK17362000A3 (sk) | 1999-11-23 | 2000-11-16 | Nukleotidové sekvencie kódujúce gén pfk |
| AU71665/00A AU7166500A (en) | 1999-11-23 | 2000-11-17 | New nucleotide sequences which code for the pfk gene |
| CA002323750A CA2323750A1 (en) | 1999-11-23 | 2000-11-20 | New nucleotide sequences which code for the pfk gene |
| US09/715,040 US6806068B1 (en) | 1999-11-23 | 2000-11-20 | Nucleotide sequences which encode the pfk gene |
| MXPA00011416A MXPA00011416A (es) | 1999-11-23 | 2000-11-21 | Nuevas secuencias nucleotidas codificantes al gen pfk. |
| JP2000354308A JP2001186895A (ja) | 1999-11-23 | 2000-11-21 | ｐｆｋ−遺伝子をコードする新規ヌクレオチド配列 |
| IDP20001005A ID28421A (id) | 1999-11-23 | 2000-11-22 | RANGKAIAN-RANGKAIAN NUKLEOTIDA YANG MENGKODE GEN pfk |
| HU0004676A HUP0004676A2 (en) | 1999-11-23 | 2000-11-22 | Novel nucleotide sequences coding for the pfk gene |
| KR1020000069629A KR20010051877A (ko) | 1999-11-23 | 2000-11-22 | ｐｆｋ유전자를 암호화하는 신규한 뉴클레오타이드 서열 |
| EP00125528A EP1103613A1 (de) | 1999-11-23 | 2000-11-22 | Für das pfk-Gen codierende Nukleotidsequenzen |
| ZA200006856A ZA200006856B (en) | 1999-11-23 | 2000-11-22 | New nucleotide sequences which code for the pfk gene. |
| PL00344076A PL344076A1 (en) | 1999-11-23 | 2000-11-23 | Polynucleotidic sequence and method of obtaining l-amino acids |
| BR0005543-3A BR0005543A (pt) | 1999-11-23 | 2000-11-23 | Sequências de nucleotédeos que codificam o gene pfk |
| CN00132502A CN1297055A (zh) | 1999-11-23 | 2000-11-23 | 编码pfk基因的新核苷酸序列 |
| US10/926,293 US20070054379A1 (en) | 1999-11-23 | 2004-08-26 | Nucleotide sequences which encode the pfk gene |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19956131A DE19956131A1 (de) | 1999-11-23 | 1999-11-23 | Neue für das pfk-Gen codierende Nukleotidsequenzen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE19956131A1 true DE19956131A1 (de) | 2001-05-31 |
Family
ID=7929914
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19956131A Withdrawn DE19956131A1 (de) | 1999-11-23 | 1999-11-23 | Neue für das pfk-Gen codierende Nukleotidsequenzen |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US6806068B1 (enExample) |
| EP (1) | EP1103613A1 (enExample) |
| JP (1) | JP2001186895A (enExample) |
| KR (1) | KR20010051877A (enExample) |
| CN (1) | CN1297055A (enExample) |
| AU (1) | AU7166500A (enExample) |
| BR (1) | BR0005543A (enExample) |
| CA (1) | CA2323750A1 (enExample) |
| DE (1) | DE19956131A1 (enExample) |
| HU (1) | HUP0004676A2 (enExample) |
| ID (1) | ID28421A (enExample) |
| MX (1) | MXPA00011416A (enExample) |
| PL (1) | PL344076A1 (enExample) |
| SK (1) | SK17362000A3 (enExample) |
| ZA (1) | ZA200006856B (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10112992A1 (de) * | 2001-03-17 | 2002-09-26 | Degussa | Verfahren zur fermentativen Herstellung von L-Aminosäuren unter Verwendung coryneformer Bakterien |
| AU2002345083A1 (en) * | 2001-07-18 | 2003-03-03 | Degussa Ag | Process for the preparation of l-amino acids using strains of the enterobacteriaceae family which contain an enhanced rsea or rsec gene |
| WO2006065967A2 (en) * | 2004-12-15 | 2006-06-22 | General Atomics | Allosteric enzyme coupled immunoassay (aecia) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4517512A (en) | 1982-05-24 | 1985-05-14 | Micro Component Technology, Inc. | Integrated circuit test apparatus test head |
| JPH07121227B2 (ja) | 1986-10-17 | 1995-12-25 | 協和醗酵工業株式会社 | Ｌ−グルタミン酸の製造法 |
| EP1010755B1 (en) | 1998-12-18 | 2010-10-06 | Ajinomoto Co., Inc. | Method for producing L-Glutamic acid by fermentation |
| KR20070087088A (ko) | 1999-06-25 | 2007-08-27 | 바스프 악티엔게젤샤프트 | 탄소 대사 및 에너지 생산과 관련된 단백질을 코딩하는코리네박테리움 글루타미쿰 유전자 |
-
1999
- 1999-11-23 DE DE19956131A patent/DE19956131A1/de not_active Withdrawn
-
2000
- 2000-11-16 SK SK1736-2000A patent/SK17362000A3/sk unknown
- 2000-11-17 AU AU71665/00A patent/AU7166500A/en not_active Abandoned
- 2000-11-20 CA CA002323750A patent/CA2323750A1/en not_active Abandoned
- 2000-11-20 US US09/715,040 patent/US6806068B1/en not_active Expired - Fee Related
- 2000-11-21 JP JP2000354308A patent/JP2001186895A/ja active Pending
- 2000-11-21 MX MXPA00011416A patent/MXPA00011416A/es unknown
- 2000-11-22 EP EP00125528A patent/EP1103613A1/de not_active Withdrawn
- 2000-11-22 KR KR1020000069629A patent/KR20010051877A/ko not_active Withdrawn
- 2000-11-22 HU HU0004676A patent/HUP0004676A2/hu unknown
- 2000-11-22 ID IDP20001005A patent/ID28421A/id unknown
- 2000-11-22 ZA ZA200006856A patent/ZA200006856B/xx unknown
- 2000-11-23 PL PL00344076A patent/PL344076A1/xx unknown
- 2000-11-23 CN CN00132502A patent/CN1297055A/zh active Pending
- 2000-11-23 BR BR0005543-3A patent/BR0005543A/pt not_active IP Right Cessation
-
2004
- 2004-08-26 US US10/926,293 patent/US20070054379A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| BR0005543A (pt) | 2001-08-07 |
| CN1297055A (zh) | 2001-05-30 |
| ID28421A (id) | 2001-05-24 |
| MXPA00011416A (es) | 2002-05-23 |
| EP1103613A1 (de) | 2001-05-30 |
| ZA200006856B (en) | 2001-07-12 |
| KR20010051877A (ko) | 2001-06-25 |
| SK17362000A3 (sk) | 2001-10-08 |
| HU0004676D0 (enExample) | 2001-02-28 |
| AU7166500A (en) | 2001-05-24 |
| HUP0004676A2 (en) | 2002-10-28 |
| PL344076A1 (en) | 2001-06-04 |
| US6806068B1 (en) | 2004-10-19 |
| US20070054379A1 (en) | 2007-03-08 |
| JP2001186895A (ja) | 2001-07-10 |
| CA2323750A1 (en) | 2001-05-23 |
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Legal Events
| Date | Code | Title | Description |
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| 8127 | New person/name/address of the applicant |
Owner name: DEGUSSA AG, 40474 DUESSELDORF, DE |
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| 8139 | Disposal/non-payment of the annual fee |