DE19911421A1 - Laser-kompatible NIR-Marker-Farbstoffe - Google Patents

Laser-kompatible NIR-Marker-Farbstoffe

Info

Publication number
DE19911421A1
DE19911421A1 DE1999111421 DE19911421A DE19911421A1 DE 19911421 A1 DE19911421 A1 DE 19911421A1 DE 1999111421 DE1999111421 DE 1999111421 DE 19911421 A DE19911421 A DE 19911421A DE 19911421 A1 DE19911421 A1 DE 19911421A1
Authority
DE
Germany
Prior art keywords
laser
marker dyes
dyes according
nir marker
compatible nir
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE1999111421
Other languages
German (de)
English (en)
Inventor
Peter Czerney
Frank Lehmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dyomics GmbH
Original Assignee
Dyomics GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dyomics GmbH filed Critical Dyomics GmbH
Priority to DE1999111421 priority Critical patent/DE19911421A1/de
Priority to PCT/DE2000/000802 priority patent/WO2000053678A1/fr
Priority to DE10080558T priority patent/DE10080558B4/de
Publication of DE19911421A1 publication Critical patent/DE19911421A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B23/00—Methine or polymethine dyes, e.g. cyanine dyes
    • C09B23/02—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B23/00—Methine or polymethine dyes, e.g. cyanine dyes
    • C09B23/10—The polymethine chain containing an even number of >CH- groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE1999111421 1999-03-11 1999-03-11 Laser-kompatible NIR-Marker-Farbstoffe Withdrawn DE19911421A1 (de)

Priority Applications (3)

Application Number Priority Date Filing Date Title
DE1999111421 DE19911421A1 (de) 1999-03-11 1999-03-11 Laser-kompatible NIR-Marker-Farbstoffe
PCT/DE2000/000802 WO2000053678A1 (fr) 1999-03-11 2000-03-09 Colorants marqueurs proches de l'infrarouge (nir) compatibles aux lasers
DE10080558T DE10080558B4 (de) 1999-03-11 2000-03-09 Laser-kompatible NIR-Marker-Farbstoffe

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE1999111421 DE19911421A1 (de) 1999-03-11 1999-03-11 Laser-kompatible NIR-Marker-Farbstoffe

Publications (1)

Publication Number Publication Date
DE19911421A1 true DE19911421A1 (de) 2000-10-05

Family

ID=7900996

Family Applications (2)

Application Number Title Priority Date Filing Date
DE1999111421 Withdrawn DE19911421A1 (de) 1999-03-11 1999-03-11 Laser-kompatible NIR-Marker-Farbstoffe
DE10080558T Expired - Fee Related DE10080558B4 (de) 1999-03-11 2000-03-09 Laser-kompatible NIR-Marker-Farbstoffe

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE10080558T Expired - Fee Related DE10080558B4 (de) 1999-03-11 2000-03-09 Laser-kompatible NIR-Marker-Farbstoffe

Country Status (2)

Country Link
DE (2) DE19911421A1 (fr)
WO (1) WO2000053678A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10140469A1 (de) * 2001-08-17 2003-03-20 Infineon Technologies Ag Karte, Dokument oder Banknote mit erhöhter Fälschungssicherheit
US6924372B2 (en) 2002-12-10 2005-08-02 Dyomics Gmbh Benzopyrylo-polymethine-based hydrophilic markers

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040054178A1 (en) * 2000-12-07 2004-03-18 Yves Madaule 1,7, and 1,9-diarylpolymethine salts
FR2827597B1 (fr) * 2001-07-20 2003-10-10 Centre Nat Rech Scient Sels de 1,9-diarylheptamethine
DE10160524A1 (de) * 2001-12-05 2003-06-26 Dyomics Gmbh Neue Fluoreszenzmarker mit großem Stokes-Shift
DE10356130A1 (de) * 2003-11-28 2005-06-23 Dyomics Gmbh Neue Polymethinfarbstoffe auf Cumarin-Basis mit einstellbarem Stokes-Shift
WO2008013543A1 (fr) * 2006-07-28 2008-01-31 Pierce Biotechnology, Inc. Composés de sondes à protéines, compositions et procédés
US7553869B2 (en) 2006-07-28 2009-06-30 Pierce Biotechnology, Inc. Protein probe compounds, compositions, and methods
WO2010138738A1 (fr) 2009-05-27 2010-12-02 Lumicell Diagnostics, Inc. Procédés et systèmes destinés à identifier de manière spatiale des cellules anormales
US9155471B2 (en) 2009-05-27 2015-10-13 Lumicell, Inc'. Methods and systems for spatially identifying abnormal cells
US9314304B2 (en) 2010-12-08 2016-04-19 Lumicell, Inc. Methods and system for image guided cell ablation with microscopic resolution
CN105473051B (zh) 2013-03-14 2019-04-30 卢米切拉有限公司 医学成像设备及使用方法
CN104086536B (zh) * 2014-06-27 2016-08-24 中国科学院化学研究所 一种用于检测pH值的荧光探针及其制备方法与专用检测试剂盒
CN106279124B (zh) * 2016-08-12 2019-04-09 中国科学院化学研究所 一种用于检测酪氨酸酶的荧光探针及其制备方法与应用
CN108997771B (zh) * 2018-06-12 2019-12-06 大连理工大学 一类在近红外区具有强吸收和光热效应的染料及其制备方法与应用
CN114591633B (zh) * 2022-01-23 2023-03-24 大连理工大学 一类氧杂蒽-半花菁近红外荧光染料，其合成方法及应用
CN114874639B (zh) * 2022-05-12 2023-07-14 大连理工大学 一类新型半花菁近红外荧光染料，其合成方法及应用

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE410487C (de) * 1922-06-04 1925-03-10 Farbenfab Vorm Bayer F & Co Verfahren zur Darstellung von Polymethinfarbstoffen
DE415534C (de) * 1924-03-11 1925-06-22 Farbenfab Vorm Bayer F & Co Verfahren zur Darstellung von Polymethinfarbstoffen
DE3912046A1 (de) * 1988-09-02 1990-03-15 Univ Carnegie Mellon Verfahren zum markieren einer komponente einer waessrigen fluessigkeit
WO1993003062A1 (fr) * 1990-05-21 1993-02-18 Coulter Corporation Procede de marquage preferentiel d'une phycobiliproteine a l'aide d'un second colorant pour permettre un dosage a couleurs multiples
WO1996004405A1 (fr) * 1994-07-29 1996-02-15 The Regents Of The University Of California Nouveaux colorants dimeres fluorescents transferant l'energie comprenant des chromophores asymetriques cyanine azole indolenine
US5569766A (en) * 1986-04-18 1996-10-29 Carnegie Mellon University Method for labeling and detecting materials employing arylsulfonate cyanine dyes
DE69215312T2 (de) * 1991-09-20 1997-04-24 Li Cor Inc Sequenzierung von im nahen Infrarot und Infrarot fluoreszierender DNA zur Detektion unter Verwendung von Laser-Dioden
US5627027A (en) * 1986-04-18 1997-05-06 Carnegie Mellon University Cyanine dyes as labeling reagents for detection of biological and other materials by luminescence methods
US5800995A (en) * 1984-03-29 1998-09-01 Li-Cor, Inc. Sequencing near infrared and infrared fluorescence labeled DNA for detecting using laser diodes and suitable labels therefor

Family Cites Families (3)

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Publication number Priority date Publication date Assignee Title
US5880287A (en) * 1990-05-15 1999-03-09 Hyperion, Inc. Polyoxyhydrocarbyl related products and methods for fluorescence assays
US5534416A (en) * 1993-04-13 1996-07-09 Molecular Probes, Inc. Fluorescent viability assay using cyclic-substituted unsymmetrical cyanine dyes
US5658751A (en) * 1993-04-13 1997-08-19 Molecular Probes, Inc. Substituted unsymmetrical cyanine dyes with selected permeability

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE410487C (de) * 1922-06-04 1925-03-10 Farbenfab Vorm Bayer F & Co Verfahren zur Darstellung von Polymethinfarbstoffen
DE415534C (de) * 1924-03-11 1925-06-22 Farbenfab Vorm Bayer F & Co Verfahren zur Darstellung von Polymethinfarbstoffen
US5800995A (en) * 1984-03-29 1998-09-01 Li-Cor, Inc. Sequencing near infrared and infrared fluorescence labeled DNA for detecting using laser diodes and suitable labels therefor
US5569766A (en) * 1986-04-18 1996-10-29 Carnegie Mellon University Method for labeling and detecting materials employing arylsulfonate cyanine dyes
US5627027A (en) * 1986-04-18 1997-05-06 Carnegie Mellon University Cyanine dyes as labeling reagents for detection of biological and other materials by luminescence methods
DE3912046A1 (de) * 1988-09-02 1990-03-15 Univ Carnegie Mellon Verfahren zum markieren einer komponente einer waessrigen fluessigkeit
WO1993003062A1 (fr) * 1990-05-21 1993-02-18 Coulter Corporation Procede de marquage preferentiel d'une phycobiliproteine a l'aide d'un second colorant pour permettre un dosage a couleurs multiples
DE69215312T2 (de) * 1991-09-20 1997-04-24 Li Cor Inc Sequenzierung von im nahen Infrarot und Infrarot fluoreszierender DNA zur Detektion unter Verwendung von Laser-Dioden
WO1996004405A1 (fr) * 1994-07-29 1996-02-15 The Regents Of The University Of California Nouveaux colorants dimeres fluorescents transferant l'energie comprenant des chromophores asymetriques cyanine azole indolenine

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DAEHNE,Siegfried, DEKHTYAR,Marina L.: Molecular Engineering Of Nir Dyes. In: Nato Asi Ser. 3, 52, 1998, S.327-362 *
GOMPPER,R., et.al.: New Nir Dyes Based On The Cyclopentadienylium Chromophore And Related Compounds. In: Nato Asi Ser. 3, 52, 1998, S.363- S.384 *
HARTMANN,K.-H., TROLL,T.: Preparation Of Naphthoquinone Imines As Nir Dyes. In: Tetrahedron, Vol.51, No.16, 1995, S.4655-4664 *
SOPER,Steven A., MATTINGLY,Quincy L.: Steady- State and Picosecond Laser Fluorescence Studies of Nonradiative Pathways in Tricarbocyanine Dyes: Implications to the Design of Near-IR Fluorochromes with High Fluorescence Efficiencies.In: J. Am. Chem. Soc. 1994, 116, S.3744-3752 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10140469A1 (de) * 2001-08-17 2003-03-20 Infineon Technologies Ag Karte, Dokument oder Banknote mit erhöhter Fälschungssicherheit
DE10140469B4 (de) * 2001-08-17 2005-09-22 Infineon Technologies Ag Karte, Dokument oder Banknote mit erhöhter Fälschungssicherheit
US6924372B2 (en) 2002-12-10 2005-08-02 Dyomics Gmbh Benzopyrylo-polymethine-based hydrophilic markers

Also Published As

Publication number Publication date
DE10080558D2 (de) 2001-06-13
WO2000053678A1 (fr) 2000-09-14
DE10080558B4 (de) 2008-09-25

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Legal Events

Date Code Title Description
OM8 Search report available as to paragraph 43 lit. 1 sentence 1 patent law
8143 Withdrawn due to claiming internal priority