DE19527140A1 - Sprühbare Lösungen mit blutdrucksenkender Wirkung und Verfahren zu ihrer Herstellung sowie ihre Verwendung - Google Patents

Sprühbare Lösungen mit blutdrucksenkender Wirkung und Verfahren zu ihrer Herstellung sowie ihre Verwendung

Info

Publication number
DE19527140A1
DE19527140A1 DE19527140A DE19527140A DE19527140A1 DE 19527140 A1 DE19527140 A1 DE 19527140A1 DE 19527140 A DE19527140 A DE 19527140A DE 19527140 A DE19527140 A DE 19527140A DE 19527140 A1 DE19527140 A1 DE 19527140A1
Authority
DE
Germany
Prior art keywords
weight
nifedipine
solution
ethyl oleate
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19527140A
Other languages
German (de)
English (en)
Inventor
Geb Kricsfalussy Nagy
Csaba Dr Farsang
Lidia Fedina
Katalin Dr Szemeredi
Gabor Szenasi
Janos Egri
Antal Mosonyi
Borbala Barta
Geb Gyarmati Toth
Ibolya Nyaradi
Frigyes Dr Goergenyi
Zsuzsa Orr
Geza Floris
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Egyt Gyogyszervegyeszeti Gyar
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of DE19527140A1 publication Critical patent/DE19527140A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Detergent Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE19527140A 1994-07-26 1995-07-25 Sprühbare Lösungen mit blutdrucksenkender Wirkung und Verfahren zu ihrer Herstellung sowie ihre Verwendung Withdrawn DE19527140A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU9402193A HU214582B (hu) 1994-07-26 1994-07-26 Porlasztható, vérnyomáscsökkentő hatású gyógyszerkészítmény és eljárás előállítására

Publications (1)

Publication Number Publication Date
DE19527140A1 true DE19527140A1 (de) 1996-02-01

Family

ID=10985460

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19527140A Withdrawn DE19527140A1 (de) 1994-07-26 1995-07-25 Sprühbare Lösungen mit blutdrucksenkender Wirkung und Verfahren zu ihrer Herstellung sowie ihre Verwendung

Country Status (18)

Country Link
JP (1) JPH08169829A (ja)
AT (1) AT402690B (ja)
AU (1) AU699386B2 (ja)
BE (1) BE1011413A4 (ja)
CZ (1) CZ286399B6 (ja)
DE (1) DE19527140A1 (ja)
EE (1) EE9500029A (ja)
FR (1) FR2722988B1 (ja)
GB (1) GB2291593B (ja)
HR (1) HRP950374A2 (ja)
HU (1) HU214582B (ja)
IT (1) IT1277348B1 (ja)
LT (1) LT4042B (ja)
LV (1) LV11026B (ja)
PL (1) PL181069B1 (ja)
SK (1) SK280463B6 (ja)
UA (1) UA39880C2 (ja)
YU (1) YU50795A (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007144082A2 (de) * 2006-06-16 2007-12-21 Lts Lohmann Therapie-Systeme Ag Antihypertonie-kombinationswafer

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030095925A1 (en) * 1997-10-01 2003-05-22 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing drugs for treating metabolic disorders
EP2042161A1 (en) * 1997-10-01 2009-04-01 Novadel Pharma Inc. Propellant-free spray composition comprising anti-emetic agent
US7632517B2 (en) 1997-10-01 2009-12-15 Novadel Pharma Inc. Buccal, polar and non-polar spray containing zolpidem
US8097614B2 (en) * 2005-02-17 2012-01-17 Velcera Pharmaceuticals, Inc. Transmucosal administration of meloxicam compositions for treating and preventing disorders in non-human domesticated animals
FR2906140B1 (fr) * 2006-09-22 2008-12-05 Philippe Perovitch Forme galenique pour l'administration par voie trans-muqueuse de principes actifs

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3307422A1 (de) * 1983-03-03 1984-09-06 Bayer Ag, 5090 Leverkusen Fluessigzubereitungen von dihydropyridinen, ein verfahren zu ihrer herstellung, sowie ihre verwendung bei der bekaempfung von erkrankungen
EP0175671A1 (de) 1984-08-23 1986-03-26 Kuhlemann & Co. Pharmazeutische Zubereitung sowie Verfahren zum Darreichen dieser pharmazeutischen Zubereitung
DE3544692A1 (de) * 1985-12-18 1987-06-19 Bayer Ag Dihydropyridinspray, verfahren zu seiner herstellung und seine pharmazeutische verwendung
ES2038696T3 (es) * 1986-03-10 1996-07-16 Burghart Kurt Procedimiento para producir un preparado farmaceutico.
US4863970A (en) * 1986-11-14 1989-09-05 Theratech, Inc. Penetration enhancement with binary system of oleic acid, oleins, and oleyl alcohol with lower alcohols
DE3779999T2 (de) * 1986-11-14 1992-12-10 Theratech Inc Erhoehung des penetrationsvermoegens mittels eines aus die zellhuelle veraendernden substanzen und kurzkettigen alkoholen bestehenden binaeren systems.
JPS63170316A (ja) * 1986-12-30 1988-07-14 Fujimoto Seiyaku Kk ニフエジピン経皮吸収外用製剤
DE3714402A1 (de) * 1987-04-30 1988-11-10 Kali Chemie Pharma Gmbh Arzneimittelformulierung
GB8828477D0 (en) * 1988-12-06 1989-01-05 Riker Laboratories Inc Medical aerosol formulations
AT391269B (de) * 1988-12-30 1990-09-10 Burghart Kurt Pharmazeutische zubereitung
US5298258A (en) * 1989-12-28 1994-03-29 Nitto Denko Corporation Acrylic oily gel bioadhesive material and acrylic oily gel preparation
HU205249B (en) * 1990-11-09 1992-04-28 Egyt Gyogyszervegyeszeti Gyar Process for producing suspensive aerosole composition

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007144082A2 (de) * 2006-06-16 2007-12-21 Lts Lohmann Therapie-Systeme Ag Antihypertonie-kombinationswafer
WO2007144082A3 (de) * 2006-06-16 2008-04-24 Lohmann Therapie Syst Lts Antihypertonie-kombinationswafer

Also Published As

Publication number Publication date
ITMI951621A1 (it) 1997-01-26
AT402690B (de) 1997-07-25
SK280463B6 (sk) 2000-02-14
AU2326995A (en) 1996-02-08
HUT75457A (en) 1997-05-28
JPH08169829A (ja) 1996-07-02
GB2291593B (en) 1998-03-11
BE1011413A4 (fr) 1999-09-07
YU50795A (sh) 1998-05-15
ATA121495A (de) 1996-12-15
FR2722988B1 (fr) 1999-10-08
SK92295A3 (en) 1996-05-08
HU214582B (hu) 1998-04-28
GB2291593A (en) 1996-01-31
HRP950374A2 (en) 1997-10-31
ITMI951621A0 (it) 1995-07-26
PL309757A1 (en) 1996-02-05
LT95084A (en) 1996-06-25
HU9402193D0 (en) 1994-09-28
LT4042B (en) 1996-09-25
CZ286399B6 (en) 2000-04-12
CZ181195A3 (en) 1996-02-14
PL181069B1 (pl) 2001-05-31
UA39880C2 (uk) 2001-07-16
LV11026A (lv) 1996-02-20
AU699386B2 (en) 1998-12-03
GB9515205D0 (en) 1995-09-20
LV11026B (en) 1996-04-20
IT1277348B1 (it) 1997-11-10
EE9500029A (et) 1996-02-15
FR2722988A1 (fr) 1996-02-02

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Legal Events

Date Code Title Description
8141 Disposal/no request for examination