DE1802394C2 - Arzneimittel mit antihypertensiver Wirkung, die [(2,6-Dichlorbenzyliden)-amino]-guanidin oder ein Säureadditionssalz davon enthalten - Google Patents

Arzneimittel mit antihypertensiver Wirkung, die [(2,6-Dichlorbenzyliden)-amino]-guanidin oder ein Säureadditionssalz davon enthalten

Info

Publication number
DE1802394C2
DE1802394C2 DE1802394A DE1802394A DE1802394C2 DE 1802394 C2 DE1802394 C2 DE 1802394C2 DE 1802394 A DE1802394 A DE 1802394A DE 1802394 A DE1802394 A DE 1802394A DE 1802394 C2 DE1802394 C2 DE 1802394C2
Authority
DE
Germany
Prior art keywords
dichlorobenzylidene
amino
acid
guanidine
addition salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE1802394A
Other languages
German (de)
English (en)
Other versions
DE1802394A1 (de
Inventor
Thomas Wayne Pa. Baum
William Fausset Havertown Pa. Bruce
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
American Home Products Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Products Corp filed Critical American Home Products Corp
Publication of DE1802394A1 publication Critical patent/DE1802394A1/de
Application granted granted Critical
Publication of DE1802394C2 publication Critical patent/DE1802394C2/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
    • C07C281/16—Compounds containing any of the groups, e.g. aminoguanidine
    • C07C281/18—Compounds containing any of the groups, e.g. aminoguanidine the other nitrogen atom being further doubly-bound to a carbon atom, e.g. guanylhydrazones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/04—Systems containing only non-condensed rings with a four-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/10—Systems containing only non-condensed rings with a five-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE1802394A 1967-10-13 1968-10-10 Arzneimittel mit antihypertensiver Wirkung, die [(2,6-Dichlorbenzyliden)-amino]-guanidin oder ein Säureadditionssalz davon enthalten Expired DE1802394C2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US67502667A 1967-10-13 1967-10-13
GB8629/68A GB1223491A (en) 1967-10-13 1968-02-22 Guanidines
US75449468A 1968-08-21 1968-08-21

Publications (2)

Publication Number Publication Date
DE1802394A1 DE1802394A1 (de) 1969-05-08
DE1802394C2 true DE1802394C2 (de) 1984-06-28

Family

ID=27255238

Family Applications (1)

Application Number Title Priority Date Filing Date
DE1802394A Expired DE1802394C2 (de) 1967-10-13 1968-10-10 Arzneimittel mit antihypertensiver Wirkung, die [(2,6-Dichlorbenzyliden)-amino]-guanidin oder ein Säureadditionssalz davon enthalten

Country Status (13)

Country Link
BE (1) BE722136A (it)
CA (2) CA958018A (it)
CH (2) CH524577A (it)
DE (1) DE1802394C2 (it)
DK (1) DK128350B (it)
FI (1) FI49958C (it)
GB (2) GB1223491A (it)
IE (1) IE32417B1 (it)
IL (1) IL30782A (it)
IT (1) IT1062053B (it)
NL (1) NL166014C (it)
PH (1) PH10262A (it)
SE (1) SE381041B (it)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH523232A (de) * 1968-12-16 1972-05-31 Sandoz Ag Verfahren zur Herstellung eines Benzylidenaminoguanidins
HU182086B (en) * 1979-06-01 1983-12-28 Wellcome Found Process for preparing new 1,2,4-triazine derivatives
JPS5625170A (en) * 1979-06-01 1981-03-10 Wellcome Found Triazine derivative
DE3360148D1 (en) * 1982-02-10 1985-06-05 Beecham Group Plc Guanidine derivatives
FR2669927B1 (fr) * 1990-11-29 1994-04-08 Adir Cie Nouveaux derives de guanidine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
GB2277090A (en) * 1993-04-16 1994-10-19 Shell Int Research Fungicidal tetrahydropyrimidine and imidazoline derivatives
SE9604348D0 (sv) * 1996-11-26 1996-11-26 Wapharm Ab Användning av hydroxyguanidiner
AU7802700A (en) * 1999-10-06 2001-05-10 Melacure Therapeutics Ab Guanidine derivatives and their use in the production of a medicament for blocking xanthine oxidase/dehydrogenase
GB0019357D0 (en) 2000-08-07 2000-09-27 Melacure Therapeutics Ab Novel phenyl guanidines
GB0108631D0 (en) * 2001-04-05 2001-05-30 Melacure Therapeutics Ab Novel benzylideneamino guanidines and their uses as ligands to the melanocortin receptors
DE10149919A1 (de) 2001-10-10 2003-04-24 Biosphings Ag Neue Salze von Guanidinderivaten und pharmazeutische Zubereitungen daraus
FR2893844B1 (fr) * 2005-11-28 2008-02-01 Centre Nat Rech Scient Utilisation du guanabenz et de ses derives pour la fabrication de medicaments pour le traitement de la mucoviscidose et de maladies liees a un defaut d'adressage des proteines dans les cellules
GB0624987D0 (en) 2006-12-14 2007-01-24 Acure Pharma Ab Novel aminoguanidines as melanocortin receptor ligands
GB201300435D0 (en) * 2013-01-10 2013-02-27 Medical Res Council Benzylideneguanidine Derivatives and Therapeutic Use for the Treatment of Protein Misfolding Diseases
DK3280405T3 (da) * 2015-04-08 2021-09-06 Res & Innovation Uk Inhibitorer og anvendelser deraf
EP3109237A1 (en) 2015-06-22 2016-12-28 AnaMar AB Novel 5-ht2 antagonists
US11166464B2 (en) * 2017-03-06 2021-11-09 The United States Of America, As Represented By The Secretary Of Agriculture Self-assembled active agents

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE958832C (de) * 1952-11-14 1957-02-28 Bayer Ag Verfahren zur Herstellung von Guanylhydrazonen
GB1019120A (en) * 1964-03-18 1966-02-02 Shell Int Research Novel hydrazine compounds and compositions containing them

Also Published As

Publication number Publication date
NL6814608A (it) 1969-04-15
IE32417B1 (en) 1973-07-25
NL166014C (nl) 1981-06-15
NL166014B (nl) 1981-01-15
GB1223492A (en) 1971-02-24
FI49958B (it) 1975-07-31
BE722136A (it) 1969-04-10
IE32417L (en) 1969-04-13
CA958018A (en) 1974-11-19
IT1062053B (it) 1983-06-25
IL30782A (en) 1972-08-30
GB1223491A (en) 1971-02-24
PH10262A (en) 1976-10-20
DK128350B (da) 1974-04-16
CH524577A (de) 1972-06-30
CA921829A (en) 1973-02-27
CH560188A5 (it) 1975-03-27
FI49958C (fi) 1975-11-10
DE1802394A1 (de) 1969-05-08
SE381041B (sv) 1975-11-24

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Legal Events

Date Code Title Description
D2 Grant after examination
8364 No opposition during term of opposition