DE1617627A1 - Verfahren zum Herstellen eines lagerstabilen,kombinierten Impfstoffes gegen Masern und Pocken - Google Patents
Verfahren zum Herstellen eines lagerstabilen,kombinierten Impfstoffes gegen Masern und PockenInfo
- Publication number
- DE1617627A1 DE1617627A1 DE19661617627 DE1617627A DE1617627A1 DE 1617627 A1 DE1617627 A1 DE 1617627A1 DE 19661617627 DE19661617627 DE 19661617627 DE 1617627 A DE1617627 A DE 1617627A DE 1617627 A1 DE1617627 A1 DE 1617627A1
- Authority
- DE
- Germany
- Prior art keywords
- vaccine
- smallpox
- measles
- virus
- combined
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 229960005486 vaccine Drugs 0.000 title claims description 30
- 238000000034 method Methods 0.000 title claims description 10
- 241000700647 Variola virus Species 0.000 title description 10
- 201000005505 Measles Diseases 0.000 title description 8
- 238000002360 preparation method Methods 0.000 title description 7
- 241000700605 Viruses Species 0.000 claims description 14
- 229940083538 smallpox vaccine Drugs 0.000 claims description 9
- 241000712079 Measles morbillivirus Species 0.000 claims description 7
- 241000700626 Cowpox virus Species 0.000 claims description 4
- 241000283973 Oryctolagus cuniculus Species 0.000 claims description 2
- 238000004519 manufacturing process Methods 0.000 claims 1
- 229940041323 measles vaccine Drugs 0.000 description 9
- 239000000203 mixture Substances 0.000 description 6
- 238000004113 cell culture Methods 0.000 description 5
- 241000282412 Homo Species 0.000 description 4
- 238000004458 analytical method Methods 0.000 description 4
- 208000015181 infectious disease Diseases 0.000 description 4
- 241001465754 Metazoa Species 0.000 description 3
- 201000003740 cowpox Diseases 0.000 description 3
- 230000036541 health Effects 0.000 description 3
- 238000002347 injection Methods 0.000 description 3
- 239000007924 injection Substances 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- 210000001519 tissue Anatomy 0.000 description 3
- 241000287828 Gallus gallus Species 0.000 description 2
- 229940124862 Measles virus vaccine Drugs 0.000 description 2
- 244000309466 calf Species 0.000 description 2
- 210000003837 chick embryo Anatomy 0.000 description 2
- 238000011109 contamination Methods 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 238000001035 drying Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 210000002257 embryonic structure Anatomy 0.000 description 2
- 239000012467 final product Substances 0.000 description 2
- 238000004108 freeze drying Methods 0.000 description 2
- 230000005180 public health Effects 0.000 description 2
- 241000283690 Bos taurus Species 0.000 description 1
- 208000032544 Cicatrix Diseases 0.000 description 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 1
- 239000003708 ampul Substances 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 210000000601 blood cell Anatomy 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 230000005802 health problem Effects 0.000 description 1
- 230000003053 immunization Effects 0.000 description 1
- 230000002458 infectious effect Effects 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 210000002751 lymph Anatomy 0.000 description 1
- 238000012792 lyophilization process Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 230000002335 preservative effect Effects 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 230000000644 propagated effect Effects 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 231100000241 scar Toxicity 0.000 description 1
- 230000037387 scars Effects 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 230000000087 stabilizing effect Effects 0.000 description 1
- 238000010254 subcutaneous injection Methods 0.000 description 1
- 239000007929 subcutaneous injection Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
- C12N2710/24134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18411—Morbillivirus, e.g. Measles virus, canine distemper
- C12N2760/18434—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Microbiology (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US48506965A | 1965-09-03 | 1965-09-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE1617627A1 true DE1617627A1 (de) | 1971-03-25 |
Family
ID=23926813
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19661617627 Pending DE1617627A1 (de) | 1965-09-03 | 1966-09-01 | Verfahren zum Herstellen eines lagerstabilen,kombinierten Impfstoffes gegen Masern und Pocken |
Country Status (8)
| Country | Link |
|---|---|
| BE (1) | BE686364A (enrdf_load_stackoverflow) |
| BR (1) | BR6682338D0 (enrdf_load_stackoverflow) |
| DE (1) | DE1617627A1 (enrdf_load_stackoverflow) |
| ES (1) | ES331077A1 (enrdf_load_stackoverflow) |
| GB (1) | GB1134435A (enrdf_load_stackoverflow) |
| IL (1) | IL26389A (enrdf_load_stackoverflow) |
| MY (1) | MY7000001A (enrdf_load_stackoverflow) |
| NL (1) | NL6612365A (enrdf_load_stackoverflow) |
-
1966
- 1966-08-24 BR BR18233866A patent/BR6682338D0/pt unknown
- 1966-08-26 IL IL2638966A patent/IL26389A/xx unknown
- 1966-08-29 ES ES0331077A patent/ES331077A1/es not_active Expired
- 1966-08-30 GB GB3866566A patent/GB1134435A/en not_active Expired
- 1966-09-01 DE DE19661617627 patent/DE1617627A1/de active Pending
- 1966-09-01 NL NL6612365A patent/NL6612365A/xx unknown
- 1966-09-02 BE BE686364D patent/BE686364A/xx unknown
-
1970
- 1970-12-31 MY MY7000001A patent/MY7000001A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BR6682338D0 (pt) | 1973-05-24 |
| BE686364A (enrdf_load_stackoverflow) | 1967-03-02 |
| GB1134435A (en) | 1968-11-20 |
| MY7000001A (en) | 1970-12-31 |
| NL6612365A (enrdf_load_stackoverflow) | 1967-03-06 |
| ES331077A1 (es) | 1967-07-01 |
| IL26389A (en) | 1970-03-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| OHW | Rejection |