DE1595883A1 - Verfahren zur Herstellung von Rifamycin-SV-Derivaten - Google Patents

Verfahren zur Herstellung von Rifamycin-SV-Derivaten

Info

Publication number
DE1595883A1
DE1595883A1 DE19651595883 DE1595883A DE1595883A1 DE 1595883 A1 DE1595883 A1 DE 1595883A1 DE 19651595883 DE19651595883 DE 19651595883 DE 1595883 A DE1595883 A DE 1595883A DE 1595883 A1 DE1595883 A1 DE 1595883A1
Authority
DE
Germany
Prior art keywords
rifamycin
formyl
lower alkyl
ecm
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE19651595883
Other languages
German (de)
English (en)
Inventor
Nicola Maggi
Piero Sensi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gruppo Lepetit SpA
Original Assignee
Lepetit SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB30327/64A external-priority patent/GB1109631A/en
Application filed by Lepetit SpA filed Critical Lepetit SpA
Priority to DE1795567A priority Critical patent/DE1795567C3/de
Priority to DE1795568A priority patent/DE1795568C3/de
Publication of DE1595883A1 publication Critical patent/DE1595883A1/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A47—FURNITURE; DOMESTIC ARTICLES OR APPLIANCES; COFFEE MILLS; SPICE MILLS; SUCTION CLEANERS IN GENERAL
    • A47F—SPECIAL FURNITURE, FITTINGS, OR ACCESSORIES FOR SHOPS, STOREHOUSES, BARS, RESTAURANTS OR THE LIKE; PAYING COUNTERS
    • A47F5/00—Show stands, hangers, or shelves characterised by their constructional features
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • G—PHYSICS
    • G09—EDUCATION; CRYPTOGRAPHY; DISPLAY; ADVERTISING; SEALS
    • G09F—DISPLAYING; ADVERTISING; SIGNS; LABELS OR NAME-PLATES; SEALS
    • G09F5/00—Means for displaying samples

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Theoretical Computer Science (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DE19651595883 1964-07-31 1965-07-28 Verfahren zur Herstellung von Rifamycin-SV-Derivaten Pending DE1595883A1 (de)

Priority Applications (2)

Application Number Priority Date Filing Date Title
DE1795567A DE1795567C3 (de) 1964-07-31 1965-07-28 Rifamycin-SV-Derivate und Verfahren zu ihrer Herstellung
DE1795568A DE1795568C3 (de) 1964-07-31 1965-07-28 3-Hydroxymethyl-rifamycin SV und Verfahren zu seiner Herstellung. Ausscheidung aus: 1595883

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB30327/64A GB1109631A (en) 1964-07-31 1964-07-31 Derivatives of rifamycin sv
FR63914A FR5518M (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1964-07-31 1966-06-02

Publications (1)

Publication Number Publication Date
DE1595883A1 true DE1595883A1 (de) 1970-02-12

Family

ID=26171063

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19651595883 Pending DE1595883A1 (de) 1964-07-31 1965-07-28 Verfahren zur Herstellung von Rifamycin-SV-Derivaten

Country Status (13)

Country Link
US (1) US3342810A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE (1) BE667697A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BR (1) BR6571577D0 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CH (1) CH458353A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE1595883A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK115993B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI45044C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (2) FR5518M (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL23930A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NL (1) NL6509961A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO118375B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SE (3) SE329895B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
YU (2) YU32700B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2227173A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1971-06-24 1972-12-28 Gruppo Lepetit S.P.A., Mailand (Italien)
DE2227087A1 (de) * 1971-06-07 1973-04-12 Lepetit Spa Neue derivate des 3-formyl-rifamycins sv
DE2433105A1 (de) * 1973-07-25 1975-02-06 Archifar Ind Chim Trentino Verfahren zur herstellung von 3iminomethylderivaten von rifamycin sv
EP0944311A4 (en) * 1996-11-19 2001-09-12 Univ Georgetown HEREGULIN ANTAGONISTS AND METHODS OF USE

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1165179A (en) * 1966-10-25 1969-09-24 Lepetit Spa Derivatives of Rifamycin SV
CH536851A (de) * 1966-10-25 1973-05-15 Ciba Geigy Ag Verfahren zur Herstellung neuer antibiotisch wirksamer Verbindungen der Rifamycinreihen
GB1159267A (en) * 1966-11-03 1969-07-23 Lepetit Spa Rifamycin Derivatives
NL145554B (nl) * 1967-06-07 1975-04-15 Lepetit Spa Werkwijze voor het bereiden van een 3-formylrifamycine sv-derivaat
FR2059967A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1969-08-06 1971-06-11 Lepetit Spa
US3933800A (en) * 1971-06-07 1976-01-20 Gruppo Lepetit S.P.A. New 3-formylrifamycin SV derivatives
US4005076A (en) * 1971-06-24 1977-01-25 Gruppo Lepetit S.P.A. Hydrazones of 3-formylrifamycin SV
BE794100A (fr) * 1972-02-23 1973-05-16 Lepetit Spa Derives 3-hydrazonomethyles de rifamycine et leur preparation
AR205434A1 (es) * 1972-03-27 1976-05-07 Lepetit Spa Proceso para la preparacion de 3-acilhidrazonometil rifamicinas sv
GB1478563A (en) * 1975-03-05 1977-07-06 Lepetit Spa Rifamycin derivatives
GB1486118A (en) * 1975-03-05 1977-09-21 Lepetit Spa Rifamycin derivatives
IT1056271B (it) * 1975-05-20 1982-01-30 Archifar Ind Chim Trentino Prodotti derivati dalle amine aromatiche
US4179439A (en) * 1977-07-01 1979-12-18 Intreprinderea De Antibiotice Iasi Rifamycins and method for their preparation
US4150023A (en) * 1977-07-01 1979-04-17 Intreprinderea De Antibiotice Iasi Hydrosoluble rifamycins and process for their preparation
GB1594134A (en) * 1977-11-25 1981-07-30 Holco Investment Inc Rifamycins
IT1090772B (it) * 1977-12-20 1985-06-26 Alfa Farmaceutici Spa Derivati della rifamicina e procedimento per la loro preparazione
IT1090771B (it) * 1977-12-20 1985-06-26 Alfa Farmaceutici Spa Derivati delle 3 carbossirifamicines ed sv e procedimento per la loro preparazione
GB1591697A (en) * 1978-03-09 1981-06-24 Archifar Lab Chim Farm Process for producing 3-amino-rifamycins s and sv
US4220657A (en) * 1978-08-11 1980-09-02 Johnson Lewis A Method for treatment of human eye disease
US4292327A (en) * 1978-08-11 1981-09-29 Johnson Lewis A Method for treatment of human eye disease
AU536524B2 (en) * 1979-06-28 1984-05-10 Gruppo Lepetit S.P.A. Water soluble hydrozones of 3-formylifamyan
US4447432A (en) * 1981-11-17 1984-05-08 Farmitalia Carlo Erba S.P.A. Azino rifamycins
IT1201963B (it) * 1983-03-24 1989-02-02 Prodotti Antibiotici Spa Derivati delle rifamicine e procedimento per la loro preparazione
GB8308166D0 (en) * 1983-03-24 1983-05-05 Erba Farmitalia Preparation of azinomethyl-rifamycins
GB8318072D0 (en) * 1983-07-04 1983-08-03 Lepetit Spa Water-soluble rifampicin derivatives
MC1617A1 (fr) * 1983-09-01 1985-07-18 Ciba Geigy Ag Nouvelles hydrazones polycycliques,procede pour leur preparation
US4681938A (en) * 1984-08-27 1987-07-21 Ciba-Geigy Corporation Novel polycyclic hydrazones of rifamycins, their manufacture, and their pharmaceutical compositions for treating tuberculosis
US4551450A (en) * 1984-08-27 1985-11-05 Ciba-Geigy Corporation Rifamycin hydrazones, pharmaceutical compositions containing them and their use
US4743619A (en) * 1985-08-29 1988-05-10 American Home Products Corporation Method of treating hepatitis
US4631290A (en) * 1985-08-29 1986-12-23 American Home Products Corporation Method of treating hepatitis
HUT47586A (en) * 1985-10-18 1989-03-28 Ciba Geigy Ag Process for production of substituated 3-/4-benzil-piperazinil/-piphamicins
US4876258A (en) * 1987-08-13 1989-10-24 Ciba-Geigy Corporation Biphenylyl compounds
US4916126A (en) * 1987-09-25 1990-04-10 Ciba-Geigy Corporation Diacyl derivatives of 4-(trialkylbenzyl)-piperazinyl compounds
GB8816620D0 (en) * 1988-07-13 1988-08-17 Lepetit Spa Rifapentine hydrohalides
EP1453837A4 (en) * 2001-11-21 2007-11-07 Activbiotics Inc TARGETED THERAPEUTIC AGENTS AND USES THEREOF
US7820652B2 (en) * 2003-09-24 2010-10-26 Activbiotics Pharma, Llc Regimen for the administration of rifamycin-class antibiotics
KR101327635B1 (ko) 2005-08-11 2013-11-12 타간타 테라퓨틱스 인크. 포스폰산화 리파마이신, 및 그의 뼈 및 관절 감염의 저지및 치료 용도
US7678791B2 (en) * 2006-07-12 2010-03-16 Cumbre Ip Ventures, L.P. Nitroheteroaryl-containing rifamycin derivatives
US20090275594A1 (en) * 2008-05-05 2009-11-05 Macielag Mark J 3-hydrazone piperazinyl rifamycin derivatives useful as antimicrobial agents
US8524691B2 (en) 2008-08-13 2013-09-03 The Medicines Company Phosphonated rifamycins and uses thereof for the prevention and treatment of bone and joint infections
RU2591188C2 (ru) 2010-11-04 2016-07-10 Альбирео Аб Ингибиторы ibat для лечения заболеваний печени
US20170202850A1 (en) 2014-07-21 2017-07-20 Hiroaki Serizawa Ophthalmic compositions of rifamycins and uses thereof
EP3534910A4 (en) * 2016-10-04 2020-11-25 Pop Test Oncology LLC THERAPEUTIC METHODS AND AGENTS
US11702443B2 (en) * 2016-10-04 2023-07-18 Pop Test Oncology Llc Therapeutic agents and methods

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2227087A1 (de) * 1971-06-07 1973-04-12 Lepetit Spa Neue derivate des 3-formyl-rifamycins sv
DE2227173A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1971-06-24 1972-12-28 Gruppo Lepetit S.P.A., Mailand (Italien)
DE2433105A1 (de) * 1973-07-25 1975-02-06 Archifar Ind Chim Trentino Verfahren zur herstellung von 3iminomethylderivaten von rifamycin sv
EP0944311A4 (en) * 1996-11-19 2001-09-12 Univ Georgetown HEREGULIN ANTAGONISTS AND METHODS OF USE

Also Published As

Publication number Publication date
DK115993B (da) 1969-12-01
CH458353A (fr) 1968-06-30
SE329895B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1970-10-26
NO118375B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1969-12-22
BE667697A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1965-11-16
YU32700B (en) 1975-06-30
NL6509961A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1966-02-01
YU1168A (en) 1973-08-31
BR6571577D0 (pt) 1973-08-14
FI45044B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1971-11-30
SE329850B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1970-10-26
YU31937B (en) 1974-02-28
YU1268A (en) 1974-12-31
IL23930A (en) 1969-04-30
FR5518M (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1967-11-06
SE329851B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1970-10-26
FR208F (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
US3342810A (en) 1967-09-19
FI45044C (fi) 1972-03-10

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Legal Events

Date Code Title Description
E77 Valid patent as to the heymanns-index 1977