DE1593026A1 - Substituierte Gonadien-Verbindungen und Verfahren zu ihrer Herstellung - Google Patents

Substituierte Gonadien-Verbindungen und Verfahren zu ihrer Herstellung

Info

Publication number
DE1593026A1
DE1593026A1 DE19661593026 DE1593026A DE1593026A1 DE 1593026 A1 DE1593026 A1 DE 1593026A1 DE 19661593026 DE19661593026 DE 19661593026 DE 1593026 A DE1593026 A DE 1593026A DE 1593026 A1 DE1593026 A1 DE 1593026A1
Authority
DE
Germany
Prior art keywords
solution
gona
water
reaction mixture
methoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE19661593026
Other languages
German (de)
English (en)
Inventor
Patchett Arthur Allan
Windholz Thomas Bela
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of DE1593026A1 publication Critical patent/DE1593026A1/de
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/566—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol having an oxo group in position 17, e.g. estrone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/14—Topical contraceptives and spermacides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
DE19661593026 1965-06-01 1966-05-25 Substituierte Gonadien-Verbindungen und Verfahren zu ihrer Herstellung Pending DE1593026A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US460505A US3370071A (en) 1965-06-01 1965-06-01 3-keto-13beta-alkyl-17beta-acetyl-gona-4, 9-dienes and process

Publications (1)

Publication Number Publication Date
DE1593026A1 true DE1593026A1 (de) 1970-10-22

Family

ID=23828981

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19661593026 Pending DE1593026A1 (de) 1965-06-01 1966-05-25 Substituierte Gonadien-Verbindungen und Verfahren zu ihrer Herstellung

Country Status (6)

Country Link
US (1) US3370071A (enExample)
BR (1) BR6680056D0 (enExample)
CH (1) CH467254A (enExample)
DE (1) DE1593026A1 (enExample)
GB (1) GB1138694A (enExample)
NL (1) NL6607589A (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989002490A1 (en) * 1987-09-16 1989-03-23 Eltech Systems Corporation Composite cell bottom for aluminum electrowinning

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3086027A (en) * 1960-01-22 1963-04-16 Lilly Co Eli 19-nor-4, 9(10)-steroids and process
US3243433A (en) * 1961-08-04 1966-03-29 Squibb & Sons Inc Steroids of the 19-norpregnane series
US3102125A (en) * 1961-09-26 1963-08-27 Syntex Corp delta5(10)-pregnene compounds
US3300518A (en) * 1961-10-04 1967-01-24 Merck & Co Inc 17alpha-trifluorovinyl androstenes
US3189528A (en) * 1963-07-25 1965-06-15 American Home Prod Resolution of racemic delta4-3-keto-13beta-alkyl steroids by using corynebacterium siplex
NL125068C (enExample) * 1964-06-01

Also Published As

Publication number Publication date
BR6680056D0 (pt) 1973-12-26
GB1138694A (en) 1969-01-01
CH467254A (de) 1969-01-15
US3370071A (en) 1968-02-20
NL6607589A (enExample) 1966-12-02

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