DE10338174A1 - Transdermale Arzneimittelzubereitungen mit Wirkstoffkombinationen zur Behandlung der Parkinson-Krankheit - Google Patents
Transdermale Arzneimittelzubereitungen mit Wirkstoffkombinationen zur Behandlung der Parkinson-Krankheit Download PDFInfo
- Publication number
- DE10338174A1 DE10338174A1 DE10338174A DE10338174A DE10338174A1 DE 10338174 A1 DE10338174 A1 DE 10338174A1 DE 10338174 A DE10338174 A DE 10338174A DE 10338174 A DE10338174 A DE 10338174A DE 10338174 A1 DE10338174 A1 DE 10338174A1
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- Prior art keywords
- combination
- group
- active
- pharmaceutical preparation
- dopa
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7092—Transdermal patches having multiple drug layers or reservoirs, e.g. for obtaining a specific release pattern, or for combining different drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (23)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10338174A DE10338174A1 (de) | 2003-08-20 | 2003-08-20 | Transdermale Arzneimittelzubereitungen mit Wirkstoffkombinationen zur Behandlung der Parkinson-Krankheit |
| AT04764129T ATE446744T1 (de) | 2003-08-20 | 2004-08-14 | Transdermale arzneimittelzubereitungen mit wirkstoffkombinationen zur behandlung der parkinson-krankheit |
| RU2005141214/15A RU2397757C2 (ru) | 2003-08-20 | 2004-08-14 | Чрескожный лекарственный препарат для лечения болезни паркинсона, содержащий сочетания действующих веществ |
| DE502004010303T DE502004010303D1 (de) | 2003-08-20 | 2004-08-14 | Transdermale arzneimittelzubereitungen mit wirkstoffkombinationen zur behandlung der parkinson-krankheit |
| CNA2004800225495A CN1832732A (zh) | 2003-08-20 | 2004-08-14 | 用于治疗帕金森氏症的含有活性物质组合的经皮药物制剂 |
| PT04764129T PT1656122E (pt) | 2003-08-20 | 2004-08-14 | Preparações medicamentosas para uma aplicação transdérmica contendo combinações de princípios activos para tratar a doença de parkinson |
| BRPI0412054-0A BRPI0412054A (pt) | 2003-08-20 | 2004-08-14 | preparação farmacêutica transdérmica |
| AU2004266063A AU2004266063B2 (en) | 2003-08-20 | 2004-08-14 | Medicament preparations for transdermal application containing active ingredient combinations for treating parkinson's disease |
| ES04764129T ES2335771T5 (es) | 2003-08-20 | 2004-08-14 | Preparaciones farmacéuticas transdérmicas con combinaciones de principios activos para el tratamiento de la enfermedad de Parkinson |
| MXPA06001815A MXPA06001815A (es) | 2003-08-20 | 2004-08-14 | Preparado farmaceutico transdermico que contiene combinaciones de principios activos para el tratamiento de la enfermedad de parkinson. |
| PL04764129T PL1656122T5 (pl) | 2003-08-20 | 2004-08-14 | Transdermalne preparaty lecznicze zawierające połączenia substancji czynnych do leczenia choroby Parkinsona |
| US10/568,941 US8980308B2 (en) | 2003-08-20 | 2004-08-14 | Transdermal pharmaceutical preparation containing active substance combinations, for treating Parkinson's disease |
| DK04764129.5T DK1656122T4 (da) | 2003-08-20 | 2004-08-14 | Transdermale lægemiddeltilberedninger med kombinationer af aktive stoffer til behandling af Parkinsons syge |
| SI200431317T SI1656122T2 (sl) | 2003-08-20 | 2004-08-14 | Transdermalni farmacevtski pripravki s kombinacijami učinkovin za zdravljenje Parkinsonove bolezni |
| CA2535063A CA2535063C (en) | 2003-08-20 | 2004-08-14 | Medicament preparations for transdermal application containing active ingredient combinations for treating parkinson's disease |
| JP2006523588A JP2007502795A (ja) | 2003-08-20 | 2004-08-14 | パーキンソン病を処置するための活性成分の組み合わせを含有する経皮適用医薬製剤 |
| NZ545593A NZ545593A (en) | 2003-08-20 | 2004-08-14 | Transdermal pharmaceutical preparation comprising L-dopa or a dopamine agonist, and an anticholinerically active substance or an NMDA receptor agonist, for treating ParkinsonÆs disease |
| PCT/EP2004/009136 WO2005018619A1 (de) | 2003-08-20 | 2004-08-14 | Transdermale arzneimittelzubereitungen mit wirkstoffkombinationen zur behandlung der parkinson-krankheit |
| KR1020067003176A KR20060065692A (ko) | 2003-08-20 | 2004-08-14 | 활성 물질 조합을 함유하는 파킨슨씨병 치료용 경피 약학적제제 |
| EP04764129A EP1656122B2 (de) | 2003-08-20 | 2004-08-14 | Transdermale arzneimittelzubereitungen mit wirkstoffkombinationen zur behandlung der parkinson-krankheit |
| ZA200509779A ZA200509779B (en) | 2003-08-20 | 2005-12-02 | Medicament preparations for transdermal application containing active ingredient combinations for treating parkinson's disease |
| IL173712A IL173712A (en) | 2003-08-20 | 2006-02-13 | Transdermal pharmaceutical preparation containing active substance combinations for treating parkinson's disease |
| JP2011275858A JP5827114B2 (ja) | 2003-08-20 | 2011-12-16 | パーキンソン病を処置するための活性成分の組み合わせを含有する経皮適用医薬製剤 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10338174A DE10338174A1 (de) | 2003-08-20 | 2003-08-20 | Transdermale Arzneimittelzubereitungen mit Wirkstoffkombinationen zur Behandlung der Parkinson-Krankheit |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE10338174A1 true DE10338174A1 (de) | 2005-03-24 |
Family
ID=34201721
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE10338174A Withdrawn DE10338174A1 (de) | 2003-08-20 | 2003-08-20 | Transdermale Arzneimittelzubereitungen mit Wirkstoffkombinationen zur Behandlung der Parkinson-Krankheit |
| DE502004010303T Expired - Lifetime DE502004010303D1 (de) | 2003-08-20 | 2004-08-14 | Transdermale arzneimittelzubereitungen mit wirkstoffkombinationen zur behandlung der parkinson-krankheit |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE502004010303T Expired - Lifetime DE502004010303D1 (de) | 2003-08-20 | 2004-08-14 | Transdermale arzneimittelzubereitungen mit wirkstoffkombinationen zur behandlung der parkinson-krankheit |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US8980308B2 (OSRAM) |
| EP (1) | EP1656122B2 (OSRAM) |
| JP (2) | JP2007502795A (OSRAM) |
| KR (1) | KR20060065692A (OSRAM) |
| CN (1) | CN1832732A (OSRAM) |
| AT (1) | ATE446744T1 (OSRAM) |
| AU (1) | AU2004266063B2 (OSRAM) |
| BR (1) | BRPI0412054A (OSRAM) |
| CA (1) | CA2535063C (OSRAM) |
| DE (2) | DE10338174A1 (OSRAM) |
| DK (1) | DK1656122T4 (OSRAM) |
| ES (1) | ES2335771T5 (OSRAM) |
| IL (1) | IL173712A (OSRAM) |
| MX (1) | MXPA06001815A (OSRAM) |
| NZ (1) | NZ545593A (OSRAM) |
| PL (1) | PL1656122T5 (OSRAM) |
| PT (1) | PT1656122E (OSRAM) |
| RU (1) | RU2397757C2 (OSRAM) |
| SI (1) | SI1656122T2 (OSRAM) |
| WO (1) | WO2005018619A1 (OSRAM) |
| ZA (1) | ZA200509779B (OSRAM) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10338174A1 (de) * | 2003-08-20 | 2005-03-24 | Lts Lohmann Therapie-Systeme Ag | Transdermale Arzneimittelzubereitungen mit Wirkstoffkombinationen zur Behandlung der Parkinson-Krankheit |
| US20070191815A1 (en) | 2004-09-13 | 2007-08-16 | Chrono Therapeutics, Inc. | Biosynchronous transdermal drug delivery |
| US8252321B2 (en) | 2004-09-13 | 2012-08-28 | Chrono Therapeutics, Inc. | Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, aids, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like |
| AU2006272978B2 (en) | 2005-07-26 | 2012-06-07 | Bial - Portela & Ca, S.A. | Nitrocatechol derivatives as COMT inhibitors |
| CN101032474B (zh) * | 2006-03-06 | 2011-02-16 | 重庆医药工业研究院有限责任公司 | 一种治疗或预防神经系统疾病的雷沙吉兰透皮贴片及其制备方法 |
| EP1845097A1 (en) | 2006-04-10 | 2007-10-17 | Portela & Ca., S.A. | Oxadiazole derivatives as COMT inhibitors |
| CN101631548B (zh) | 2007-01-31 | 2014-08-27 | 比艾尔-坡特拉有限公司 | Comt抑制剂的单次药物剂量单元和药物组合物 |
| RU2326660C1 (ru) * | 2007-03-14 | 2008-06-20 | Закрытое акционерное общество "Биологические исследования и системы" | Пероральный лекарственный препарат мемантин (варианты) и способ его получения (варианты) |
| ES2521494T3 (es) * | 2007-04-02 | 2014-11-12 | Parkinson's Institute | Métodos y composiciones para la reducción de los efectos secundarios de tratamientos terapéuticos |
| WO2008129043A1 (en) * | 2007-04-24 | 2008-10-30 | Boehringer Ingelheim International Gmbh | Combination with an extended release tablet formulation containing pramipexole or a pharmaceutically acceptable salt thereof |
| ES2723729T3 (es) * | 2008-07-29 | 2019-08-30 | Bial Portela & Ca Sa | Régimen de administración de nitrocatecoles |
| KR102023255B1 (ko) | 2009-04-01 | 2019-09-19 | 바이알 - 포르텔라 앤드 씨에이 에스에이 | 니트로카테콜 유도체를 포함하는 제약 제제 및 그의 제조 방법 |
| KR101292768B1 (ko) * | 2010-04-23 | 2013-08-05 | 아이큐어 주식회사 | 경피 흡수 제제 |
| JP5820469B2 (ja) | 2010-04-30 | 2015-11-24 | テイコク ファーマ ユーエスエー インコーポレーテッド | プロピニルアミノインダンの経皮組成物 |
| DE102010024105A1 (de) * | 2010-06-17 | 2011-12-22 | Grünenthal GmbH | Transdermale Verabreichung von Memantin |
| US20140045900A1 (en) | 2011-02-11 | 2014-02-13 | Bial-Portela & Ca, S.A. | Administration regime for nitrocatechols |
| EP2705842A1 (en) * | 2012-09-05 | 2014-03-12 | Pharnext | Therapeutic approaches for treating parkinson's disease |
| CN103476404B (zh) | 2011-03-24 | 2017-09-29 | 帝国制药美国公司 | 包含活性剂层和活性剂转化层的透皮组合物 |
| US20130017259A1 (en) | 2011-07-06 | 2013-01-17 | The Parkinson's Institute | Compositions and Methods for Treatment of Symptoms in Parkinson's Disease Patients |
| WO2013070526A1 (en) | 2011-11-09 | 2013-05-16 | Teikoku Pharma Usa, Inc. | Methods for the treatment of skin neoplasms |
| BR112014014341A2 (pt) | 2011-12-13 | 2017-08-22 | Bial Portela & Ca Sa | Intermediário metilado, seu método de preparação e seus usos, e composição farmacêutica |
| US20130197023A1 (en) * | 2012-01-27 | 2013-08-01 | California Institute Of Technology | Neuroprotection by pharmacological chaperoning of nicotinic acetylcholine receptors |
| AU2013338243B2 (en) | 2012-11-02 | 2016-09-29 | Teikoku Seiyaku Co., Ltd. | Propynylaminoindan transdermal compositions |
| KR20160026897A (ko) | 2013-06-27 | 2016-03-09 | 세다르스-신나이 메디칼 센터 | 신경퇴행성 질환의 예방 및 치료를 위한 아드레날린 수용체 길항제 |
| CN103622997A (zh) * | 2013-11-22 | 2014-03-12 | 内蒙古医科大学 | 包含谷氨酸受体阻断剂盐酸美金刚或其药学可接受的盐与β受体阻断剂的药物组合物 |
| EP2946775A1 (de) | 2014-05-20 | 2015-11-25 | LTS LOHMANN Therapie-Systeme AG | Lavendelöl enthaltendes transdermales therapeutisches System |
| WO2016083863A1 (en) | 2014-11-28 | 2016-06-02 | Bial - Portela & Ca, S.A. | Medicaments for slowing parkinson's disease |
| CN104510725B (zh) * | 2015-01-22 | 2021-04-27 | 中国药科大学 | 一种普拉克索周效透皮贴剂及其制备方法 |
| WO2016123406A1 (en) | 2015-01-28 | 2016-08-04 | Chrono Therapeutics Inc. | Drug delivery methods and systems |
| EP3267875A4 (en) | 2015-03-12 | 2018-12-05 | Chrono Therapeutics Inc. | Craving input and support system |
| EP3522843B1 (en) * | 2016-10-07 | 2022-09-21 | Transwell Biotech Co., Ltd. | Pramipexole transdermal delivery system and uses thereof |
| WO2018129304A1 (en) | 2017-01-06 | 2018-07-12 | Chrono Therapeutics Inc. | Transdermal drug delivery devices and methods |
| US12459965B2 (en) | 2017-10-09 | 2025-11-04 | Compass Pathfinder Limited | Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use |
| GB2571696B (en) | 2017-10-09 | 2020-05-27 | Compass Pathways Ltd | Large scale method for the preparation of Psilocybin and formulations of Psilocybin so produced |
| CA3101966A1 (en) | 2018-05-29 | 2019-12-05 | Morningside Venture Investments Limited | Drug delivery methods and systems |
| US12397141B2 (en) | 2018-11-16 | 2025-08-26 | Morningside Venture Investments Limited | Thermally regulated transdermal drug delivery system |
| JP2022529781A (ja) | 2019-04-17 | 2022-06-24 | コンパス パスファインダー リミテッド | サイロシビンによるうつ病及び他の様々な障害の治療 |
| US20240299501A1 (en) * | 2023-03-06 | 2024-09-12 | Xygenyx Inc. | Composition and methods of treatment using transdermal hormone supplementation |
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2003
- 2003-08-20 DE DE10338174A patent/DE10338174A1/de not_active Withdrawn
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2004
- 2004-08-14 CN CNA2004800225495A patent/CN1832732A/zh active Pending
- 2004-08-14 PL PL04764129T patent/PL1656122T5/pl unknown
- 2004-08-14 BR BRPI0412054-0A patent/BRPI0412054A/pt not_active IP Right Cessation
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- 2004-08-14 MX MXPA06001815A patent/MXPA06001815A/es active IP Right Grant
- 2004-08-14 US US10/568,941 patent/US8980308B2/en active Active
- 2004-08-14 DE DE502004010303T patent/DE502004010303D1/de not_active Expired - Lifetime
- 2004-08-14 KR KR1020067003176A patent/KR20060065692A/ko not_active Ceased
- 2004-08-14 AU AU2004266063A patent/AU2004266063B2/en not_active Ceased
- 2004-08-14 PT PT04764129T patent/PT1656122E/pt unknown
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- 2004-08-14 ES ES04764129T patent/ES2335771T5/es not_active Expired - Lifetime
- 2004-08-14 DK DK04764129.5T patent/DK1656122T4/da active
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- 2004-08-14 WO PCT/EP2004/009136 patent/WO2005018619A1/de not_active Ceased
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- 2004-08-14 AT AT04764129T patent/ATE446744T1/de active
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