DE10334040A1 - Neue N-substituierte Indolyl-3-glyoxylsäureamide, deren Verwendung als Arzneimittel und Verfahren zu deren Herstellung - Google Patents

Neue N-substituierte Indolyl-3-glyoxylsäureamide, deren Verwendung als Arzneimittel und Verfahren zu deren Herstellung Download PDF

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Publication number
DE10334040A1
DE10334040A1 DE10334040A DE10334040A DE10334040A1 DE 10334040 A1 DE10334040 A1 DE 10334040A1 DE 10334040 A DE10334040 A DE 10334040A DE 10334040 A DE10334040 A DE 10334040A DE 10334040 A1 DE10334040 A1 DE 10334040A1
Authority
DE
Germany
Prior art keywords
medicaments
novel
preparation
acid amides
glyoxylic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE10334040A
Other languages
German (de)
English (en)
Inventor
Matthias Gerlach
Tilmann Schuster
Peter Schmidt
Silke Baasner
Eckhard Guenther
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aeterna Zentaris GmbH
Original Assignee
Zentaris AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zentaris AG filed Critical Zentaris AG
Priority to DE10334040A priority Critical patent/DE10334040A1/de
Priority to CA002533433A priority patent/CA2533433A1/en
Priority to MXPA06000995A priority patent/MXPA06000995A/es
Priority to RU2006105708/04A priority patent/RU2317293C9/ru
Priority to AU2004263238A priority patent/AU2004263238A1/en
Priority to KR1020067001636A priority patent/KR20060037398A/ko
Priority to EP04740854A priority patent/EP1651600A2/de
Priority to CNA2004800240832A priority patent/CN1839129A/zh
Priority to YUP-2006/0049A priority patent/RS20060049A/sr
Priority to PCT/EP2004/007573 priority patent/WO2005014542A2/de
Priority to JP2006521430A priority patent/JP2007503376A/ja
Priority to BRPI0412898-2A priority patent/BRPI0412898A/pt
Priority to TW093121509A priority patent/TW200524863A/zh
Priority to ARP040102632A priority patent/AR045928A1/es
Priority to UAA200601216A priority patent/UA83498C2/uk
Publication of DE10334040A1 publication Critical patent/DE10334040A1/de
Priority to IL173335A priority patent/IL173335A0/en
Priority to ZA200601300A priority patent/ZA200601300B/xx
Priority to NO20060697A priority patent/NO20060697L/no
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE10334040A 2003-07-25 2003-07-25 Neue N-substituierte Indolyl-3-glyoxylsäureamide, deren Verwendung als Arzneimittel und Verfahren zu deren Herstellung Withdrawn DE10334040A1 (de)

Priority Applications (18)

Application Number Priority Date Filing Date Title
DE10334040A DE10334040A1 (de) 2003-07-25 2003-07-25 Neue N-substituierte Indolyl-3-glyoxylsäureamide, deren Verwendung als Arzneimittel und Verfahren zu deren Herstellung
PCT/EP2004/007573 WO2005014542A2 (de) 2003-07-25 2004-07-09 Neue n-substituierte indolyl-3-glyoxylsäureamide, deren verwendung als arzneimittel gegen krebs und verfahren zu deren herstellung
JP2006521430A JP2007503376A (ja) 2003-07-25 2004-07-09 新規ｎ−置換インドリル−３−グリオキシル酸アミド、医薬品としてのその使用及びその製造方法
RU2006105708/04A RU2317293C9 (ru) 2003-07-25 2004-07-09 N-замещенные амиды индолил-3-глиоксиловой кислоты противоопухолевого действия, лекарственное средство на их основе, способ их получения и способ лечения опухолевых заболеваний
AU2004263238A AU2004263238A1 (en) 2003-07-25 2004-07-09 Novel N-substituted indolyl-3-glyoxylic acid amides, use thereof as a medicament, and method for the production thereof
KR1020067001636A KR20060037398A (ko) 2003-07-25 2004-07-09 신규한 ｎ-치환된 인돌릴-3-글리옥실산 아미드, 약제로서의이의 용도 및 이의 제조방법
EP04740854A EP1651600A2 (de) 2003-07-25 2004-07-09 Neue n-substituierte indolyl-3-glyoxysäureamide, deren verwendung als arzneimittel gegen krebs und verfahren zu deren herstellung
CNA2004800240832A CN1839129A (zh) 2003-07-25 2004-07-09 新的n－取代吲哚基－3－乙醛酰胺,其作为药物的用途及其制备方法
YUP-2006/0049A RS20060049A (xx) 2003-07-25 2004-07-09 Novi n-supstituisani amidi indolil-3-glioksilne kiseline, njihova upotreba kao leka i postupak za njihovo dobijanje
CA002533433A CA2533433A1 (en) 2003-07-25 2004-07-09 Novel n-substituted indolyl-3-glyoxylic acid amides, use thereof as a medicament, and method for the production thereof
MXPA06000995A MXPA06000995A (es) 2003-07-25 2004-07-09 Amidas novedosas de acido indolil-3-glioxilico sustituidas en el atomo de n, uso de las mismas como medicamento y metodo para la produccion de las mismas.
BRPI0412898-2A BRPI0412898A (pt) 2003-07-25 2004-07-09 amidas de ácido indolil-3-glioxìlico n-substituìdas, seu uso como um medicamento, e processo para sua produção
TW093121509A TW200524863A (en) 2003-07-25 2004-07-19 Novel N-substituted indolyl-3-glyoxylamides, their use as medicaments and process for their preparation
ARP040102632A AR045928A1 (es) 2003-07-25 2004-07-23 Amidas n-sustituidas de acido indolil-3-glioxilico, su uso como medicamentos y procedimiento para su preparacion
UAA200601216A UA83498C2 (uk) 2003-07-25 2004-09-07 N-заміщені аміди індоліл-3-гліоксилової кислоти, їх застосування як лікарського засобу і спосіб їх одержання
IL173335A IL173335A0 (en) 2003-07-25 2006-01-24 Novel n-substituted indolyl-3-glyoxylic acid amides, use thereof as a medicament, and method for the production thereof
ZA200601300A ZA200601300B (en) 2003-07-25 2006-02-13 Novel n-substituted indolyl-3-glyoxylic acid amides, use thereof as a medicament, and method for the production thereof
NO20060697A NO20060697L (no) 2003-07-25 2006-02-14 Nye N-substituerte indolyl-3-glyoksylsyreamider, anvendelse derav som medikament og fremgangsmate for fremstilling derav

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10334040A DE10334040A1 (de) 2003-07-25 2003-07-25 Neue N-substituierte Indolyl-3-glyoxylsäureamide, deren Verwendung als Arzneimittel und Verfahren zu deren Herstellung

Publications (1)

Publication Number Publication Date
DE10334040A1 true DE10334040A1 (de) 2005-03-10

Family

ID=34129467

Family Applications (1)

Application Number Title Priority Date Filing Date
DE10334040A Withdrawn DE10334040A1 (de) 2003-07-25 2003-07-25 Neue N-substituierte Indolyl-3-glyoxylsäureamide, deren Verwendung als Arzneimittel und Verfahren zu deren Herstellung

Country Status (18)

Country Link
EP (1) EP1651600A2 (xx)
JP (1) JP2007503376A (xx)
KR (1) KR20060037398A (xx)
CN (1) CN1839129A (xx)
AR (1) AR045928A1 (xx)
AU (1) AU2004263238A1 (xx)
BR (1) BRPI0412898A (xx)
CA (1) CA2533433A1 (xx)
DE (1) DE10334040A1 (xx)
IL (1) IL173335A0 (xx)
MX (1) MXPA06000995A (xx)
NO (1) NO20060697L (xx)
RS (1) RS20060049A (xx)
RU (1) RU2317293C9 (xx)
TW (1) TW200524863A (xx)
UA (1) UA83498C2 (xx)
WO (1) WO2005014542A2 (xx)
ZA (1) ZA200601300B (xx)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5406716B2 (ja) 2006-08-07 2014-02-05 アイアンウッド ファーマシューティカルズ インコーポレイテッド インドール化合物
AR084433A1 (es) 2010-12-22 2013-05-15 Ironwood Pharmaceuticals Inc Inhibidores de la faah y composiciones farmaceuticas que los contienen

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003022280A2 (en) * 2001-09-13 2003-03-20 Synta Pharmaceuticals Corp. 3-glyoxlylamideindoles for treating cancer

Also Published As

Publication number Publication date
IL173335A0 (en) 2006-06-11
ZA200601300B (en) 2007-03-28
EP1651600A2 (de) 2006-05-03
RU2317293C2 (ru) 2008-02-20
RU2006105708A (ru) 2006-06-27
JP2007503376A (ja) 2007-02-22
RU2317293C9 (ru) 2008-05-10
NO20060697L (no) 2006-02-14
RS20060049A (xx) 2008-08-07
TW200524863A (en) 2005-08-01
WO2005014542A3 (de) 2006-10-19
CN1839129A (zh) 2006-09-27
KR20060037398A (ko) 2006-05-03
AU2004263238A1 (en) 2005-02-17
BRPI0412898A (pt) 2006-10-03
MXPA06000995A (es) 2006-04-11
WO2005014542A2 (de) 2005-02-17
UA83498C2 (uk) 2008-07-25
AR045928A1 (es) 2005-11-16
CA2533433A1 (en) 2005-02-17

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Legal Events

Date Code Title Description
OR8 Request for search as to paragraph 43 lit. 1 sentence 1 patent law
8105 Search report available
8127 New person/name/address of the applicant

Owner name: AETERNA ZENTARIS GMBH, 60314 FRANKFURT, DE

8139 Disposal/non-payment of the annual fee